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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Journal of Nutrition,Fasting and Health
- نوع مقاله: Journal Article
- کلمات کلیدی: micronutrients,Ramadan fasting,Anterior chamber depth,Axial length
- چکیده:
- چکیده انگلیسی: Introduction: The present study aimed to assess the effects of Ramadan fasting on micronutrients and their correlations with ocular biometry. Methods: This prospective study was conducted on 89 healthy volunteers (51 males and 38 females) with the mean of 34.98±9.10 years in Mashhad, Iran. Participants received complete ophthalmic and systemic examinations one week before and one week after the holy month of Ramadan in 2015. Subjects with no history of systemic and ophthalmic diseases were enrolled in the study. Blood samples were obtained from all the participants in the morning in both phases of the study. Levels of micronutrients were measured in the blood samples using the Hitachi 717 analyzer (Hitachi, Japan). In addition, IOLMaster (Carl Zeiss Meditec AG, Germany) was applied to determine the ocular axial length (AL) and anterior chamber depth (ACD). Results: No significant differences were observed in the AL and ACD of the subjects before and after Ramadan fasting (P>0.05). Fasting was found to decrease the levels of uric acid, selenium, sodium, and potassium (P<0.05). However, serum phosphor was observed to increase after the fasting period (P=0.032). No changes were reported in the concentrations of the other micronutrients, including urea, calcium, iron, zinc, creatinine, and albumin (P>0.05). Moreover, no significant association was observed between the AL and ACD with the concentrations of the micronutrients during Ramadan (P>0.05). Conclusion: According to the results, fasting had no significant effects on the overall health and ocular biometry of the fasting individuals during Ramadan. Therefore, it seems that Ramadan fasting is a safe for healthy adults.
- انتشار مقاله: 30-09-1396
- نویسندگان: Fatemeh Shahsavan,Sattar Rajabi,Mohammad Reza Sedaghat,Mohsen Nematy,Javad Heravian Shandiz,Maryam Sadat Amirkalali Sijavandi,Zahra Mahmoudi,Nasrin Moghadas Sharif
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Nutrition,Fasting and Health
- نوع مقاله: Journal Article
- کلمات کلیدی: fasting,Ramadan,IOP,Serum electrolyte
- چکیده:
- چکیده انگلیسی: Introduction: Annually, millions of Muslims all over the world observe the fasting rules based on its measures; this highlights the importance of studies in this field as a worthwhile model for intermittent fasting. It is obvious that changes in lifestyle over fasting have outstanding effects on physiological parameters. The current study was carried out to investigate the IOP and serum electrolytes as two important factors that are influenced by human lifestyle. Methods: Eighty-nine fasting and healthy participants including men and women with mean age of 34.97 were included in our study based on the inclusion and exclusion parameters. During this project, Ramadan coincided with the summer (between June and July 2015). All participants were monitored by an expert examiner and blood samples were collected and IOP was measured by tonometer (Topcon, 1-75, Hasunuma-cho, Itabashi-KU, Tokyo, Japan 2014). The participants were examined one week before and one week after Ramadan. Results: There was a significant reduction in physiological IOP in healthy people after Ramadan. In line with this, the serum electrolytes were altered by fasting so that Na, K, Se experienced a significant decrease while serum phosphorous increased (P<0.05). Conclusion: Prolonged intermittent fasting in Ramadan changed IOP and serum electrolytes in healthy people within a normal range.
- انتشار مقاله: 21-03-1396
- نویسندگان: Rahil Karimi Rad,Mohsen Nematy,Mohamad-Reza Sedaghat,Farshad Askarizade,Tahereh Rakhshandadi,Zahra Mahmoudi,Mehrane Mehramiz,Javad Heravian
- مشاهده
- جایگاه : پژوهشی
- مجله: Avicenna Journal of Phytomedicine
- نوع مقاله: Journal Article
- کلمات کلیدی: Proliferation,Alkaline phosphatase,Foeniculum vulgare,Osteogenesis
- چکیده:
- چکیده انگلیسی: Objective: Osteoporosis or silent disease is a major bone disorder in elderly women in current century. Estrogen has an important role in osteogenesis and prevention of bone fractures. Hormone replacement therapy (HRT) is usually accompanied by such effects as breast and ovary cancers. Thus, there is an increasing demand for replacement with plant phytoestrogens. This study is focused on determining the effects of Foeniculum vulgare extract on proliferation and osteogenesis progress in human mesenchymal stem cells.
Material and Methods: Human mesenchymal stem cells were isolated and treated with different amount of plant extracts (0.5 to 100 µg/ml). Extract cytotoxicity was measured using MTT assay. The alkaline phosphatase enzyme activity was measured to evaluate the differentiation progress.
Results: Results of MTT assay and alkaline phosphatase activity showed that Foeniculum vulgare extract, at range of 5 to 50 µg/ml, may positively affect cell proliferation and mineralization. The most proliferation and enzyme activity were seen with dose of 5 µg/ml.
Conclusions: Foeniculum vulgare has been used in Iranian folk medicine for many years. Our in vitro study showed that Foeniculum vulgare extract has osteoprotective effects.- انتشار مقاله: 21-03-1391
- نویسندگان: Zahra Mahmoudi,Masoud Soleimani,Abbas Saidi,Gholamreza Khamisipour,Arezoo Azizsoltani
- مشاهده