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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Journal of Patient Safety & Quality Improvement
- نوع مقاله: Journal Article
- کلمات کلیدی: toxicology,Fellowship,likert,heart training
- چکیده:
- چکیده انگلیسی: Introduction: Nowadays, patients referring to emergency department due to poisoning and its complications, make up most of the patients in emergency wards. One of the major complications of these poisonings is heart problems. With this in mind, we decided on training courses to repeat the topics and cardiovascular emergencies for toxicology assistants and other toxicology specialists.
Materials and Methods: For this study invited of clinical toxicology residents and toxicologists and forensic specialists and other specialists in toxicology ward to attend ECG training classes and cardiac emergencies. Ten people attended classes. Pre-test training with eight items was taken before the start of training. It was explained that individuals should score from 1(very poor) to 5(very strong) based on Likert. And after the end of the course, the post- test was done with the same condition.
Results: According to the results obtained from the table and questions, we came to the conclusion that the training courses have improved results in all items and courses are required at least once a year.
Conclusion: It seems that cardiovascular training is repeated annually for toxicology assistants and other toxicology specialists can be helpful in remembering previous material and better treating patients in toxicology emergency.- انتشار مقاله: 20-09-1398
- نویسندگان: Zahra Ataee,Bita Dadpour,Maliheh Ziaee,Majid Jalalyazdi
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Kerman University of Medical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: Diphenhydramine,Quince seed mucilage,Aluminum magnesium,Topical anesthesia
- چکیده:
- چکیده انگلیسی: Background & Aims: The topical anesthetic effects of diphenhydramine combined with ingredients such as aluminum and magnesium hydroxide have been used for many years in modern medicine. Due to the limited durability of anesthetic mouthwashes due to saliva secretion and the spreading use of herbal and natural medicines in pharmacotherapy, this study was designed to formulate diphenhydramine in the mucilage of quince seed and evaluate its in-vitro properties and clinical anesthetic effect. Methods: This research was a descriptive laboratory and double-blind clinical study on 4 formulations. Diphenhydramine in quince seed mucilage, diphenhydramine and aluminum magnesium hydroxide combination, diphenhydramine solution, and diphenhydramine elixir and aluminum magnesium hydroxide combination were administered to 12 healthy male volunteers. The age range of the participants was 20 to 30 years. All subjects signed informed consent forms. Diphenhydramine release from the formulations was assessed through cellulosic membrane in Franz diffusion cell. The clinical evaluation of the formulations on healthy volunteers was conducted through prescribing mouthwash use for 2 minutes and controlling the duration its effect in 10, 20, and 30 minutes after administration using a questionnaire. Data analysis was performed using Kruskal-Wallis and Mann-Whitney tests. Results: The duration of effect of diphenhydramine in quince seed mucilage base was at least 3 times longer than diphenhydramine solution and aluminum Mg and the diphenhydramine elixir and aluminum Mg combination. Clinical evaluation showed that the diffusion coefficient of diphenhydramine in the quince seed mucilage base was significantly different from that of the diphenhydramine solution and diphenhydramine and aluminum Mg combination (P < 0.010). However, it was not significantly different from the diphenhydramine elixir and aluminum Mg combination (P = 0.204). Conclusion: The results of in-vitro and clinical studies showed that diphenhydramine in mucilage of quince seed can sustain and control the release of diphenhydramine and can be administered instead of the diphenhydramine elixir and aluminum Mg combination.
- انتشار مقاله: 22-04-1395
- نویسندگان: Zahra Ataee,Ghorban Abedini,Razieh Sadat Rezvaninejad,Mehdi Ansari
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Emergency Practice and Trauma
- نوع مقاله: Journal Article
- کلمات کلیدی: Tramadol,Hypoxic ischemic encephalopathy,Antiepileptic,Status epilepticus
- چکیده:
- چکیده انگلیسی: Objective: Tramadol is a synthetic analgesic with two mechanisms. The opioid and non-opioid mechanisms are responsible for tramadol side effects. Non-opioid side effects of tramadol are due to the reuptake inhibitions of serotonin and norepinephrine. Some of the side effects include anaphylactoid reactions, CNS depression, hypoglycemia, hypotension, respiratory depression, seizures, and serotonin syndrome. Seizure may happen in therapeutic doses. If the frequency of tramadol seizures increases, ischemic brain injury and hypoxic-ischemic encephalopathy can be induced.
Case Report: We report a young man with a history of tramadol abuse that was admitted with status epilepticus in Imam Reza hospital in Mashhad, Iran. Due to his altered mental status, he was intubated and antiepileptic agents were prescribed. He was transferred to ICU. After regaining consciousness, he was extubated and with the prescription of rehabilitation support he was discharged.
Conclusion: Tramadol is a synthetic analgesic agent with less potential for dependence. It is important to mention that the overdose of this drug is common. This drug has two mechanisms. This paper reports a case that developed generalized tonic clonic seizures due to tramadol and hypoxic ischemic encephalopathy. With adequate treatment and supportive care, patient’s mental status improves and he/she can be discharged.- انتشار مقاله: 01-07-1398
- نویسندگان: Zahra Ataee,Bita Dadpour
- مشاهده
- جایگاه : پژوهشی
- مجله: Future of Medical Education Journal
- نوع مقاله: Journal Article
- کلمات کلیدی: Clinical toxicology,Multidisciplinary,Programmed conferences
- چکیده:
- چکیده انگلیسی: Medical management, is a team work and the nature of clinical toxicology is multidisciplinary. Internal organs problems following intoxications are included in field of internal medicine; similar problems in poisoned children brings pediatric medicine into the arena. The emergency nature of many acute intoxications, the legal problems of poisoned patients, respiratory assist in unconscious cases or need to sedate sever agitation in some intoxicated patients on the contrary, require the expertise of emergency medicine, forensic medicine, and anesthesiology, respectively.
Multidisciplinary nature of clinical toxicology is a valuable point; so that, incorporating various medical specialties, gives great power to clinical toxicology groups. On the other hand, this diversity in specialties leads to a variety of viewpoints on dealing with poisoned patients.
The key point sessions have been held in Mashhad CTD for the past 18 months and considering the wide range of topics, the need to continue these sessions in the coming years is quietly felt.- انتشار مقاله: 14-07-1398
- نویسندگان: Zahra Ataee,Bita Dadpour
- مشاهده
- جایگاه : پژوهشی
- مجله: Asia Pacific Journal of Medical Toxicology
- نوع مقاله: Journal Article
- کلمات کلیدی: Acute liver failure,Liver Function Tests,Icterus,Tribulus terrestris
- چکیده:
- چکیده انگلیسی: Background: Plants have been used for the treatment of a wide range of conditions since ancient times but some have side effects and toxic effects that limit their use. Tribulus terrestris is traditionally used for lowering blood pressure, inhibiting kidney stone formation and inducing weight loss. In this case study, we present an Iranian woman who suffered from liver failure after using this plant.
Case presentation: A 31-year-old Iranian woman was admitted to Emam-Reza hospital due to epigastric pain radiating to back and shoulders, and weakness, Malas,neusia and icterus. Upon admission,, her vital signs were normal. She had been consuming Tribulus terrestris as an herbal tea , several times a day for 2-3 months, in order to lose weight. Upon physical examination, the patient had generalized icterus and laboratory tests showed elevated transaminases, PT, and INR. Various causes of hepatic failure, such as viral hepatitis and autoimmune hepatitis, were ruled out and the only probable diagnosis was toxin-induced liver failure.
Conclusion: Herbal plants may have some beneficial medical effects but they can also cause toxicity. Consistent use and high dose of Tribulus terrestris may cause hepatic failure and death.- انتشار مقاله: 21-07-1396
- نویسندگان: Zahra Ataee,Bita Dadpour
- مشاهده