• جایگاه : پژوهشی
• مجله: Asia Oceania Journal of Nuclear Medicine and Biology
• نوع مقاله: Journal Article
• کلمات کلیدی: Thyroid Volume,Single-photon Emission Computed Tomography,Software,Ultrasonography
• چکیده:
• چکیده انگلیسی: Objective(s): In this study, we aimed to evaluate the efficacy of thyroid volume measurement using 99mTc pertechnetate single-photon emission computed tomography (SPECT) images, acquired by the standardized uptake value (SUV)-shape scheme designed by our expert team.
  Methods: A total of 18 consecutive patients with Graves’ disease (GD) were subjected to both ultrasonographic and 99mTc pertechnetate SPECT examinations of thyroid within a five-day interval. The volume of thyroid lobes and isthmus was measured by ultrasonography (US) according to the ellipsoid volume equation. The total thyroid volume, determined as the sum of the volume of both lobes and isthmus, was recorded as TV-US (i.e., thyroid volume measured by US) and set as the reference. The thyroid volume was defined according to our SUV-shape scheme and was recorded as TV-SS (i.e., thyroid volume determined by the SUV-shape scheme). The data were analyzed using the Bland-Altman plot, linear regression analysis, Spearman’s rank correlation, and paired t-test, if necessary.
  Results: The values of TV-SS (40.2±29.4 mL) and TV-US (43.0±34.7 mL) were not significantly different (t=0.813; P=0.43). The linear regression equation of the two values was determined as TV-US= 1.072 × TV-SS − 0.29(r=0.906; P<0.01).
  Conclusion: The new scheme, i.e., SUV-shape scheme, exhibited potential for the measurement of thyroid volume in patients with GD.
• انتشار مقاله: 06-11-1394
• نویسندگان: Yangchun Chen,SiPei Xie,Fang He,JianWei Chen
• مشاهده

• جایگاه : پژوهشی
• مجله: Asia Oceania Journal of Nuclear Medicine and Biology
• نوع مقاله: Journal Article
• کلمات کلیدی: Positron Emission Tomography,Gross tumor volume,internal tumor volume,standardized uptake value
• چکیده:
• چکیده انگلیسی:
  Objective(s): Considering the fact that the standardized uptake value (SUV) of a normal lung tissue is expressed as x±SD, x+3×SD could be considered as the threshold value to outline the internal tumor volume (ITV) of a lung neoplasm.
  Methods: Three hollow models were filled with 55.0 kBq/mL fluorine18- fluorodeoxyglucose (18F-FDG) to represent tumors. The models were fixed to a barrel filled with 5.9 kBq/mL 18F-FDG to characterize normal lung tissues as a phantom. The PET/CT images of the phantom were acquired at rest. Then, the barrel was moved periodically to simulate breathing while acquiring PET/CT data. Volume recovery coefficient (VRC) was applied to evaluate the accuracy of ITVs. For statistical analysis, paired t-test and analysis of variance were applied.
  Results: The VRCs ranged from 0.74 to 0.98 and significantly varied among gross tumor volumes for delineating ITV (P<0.01). In two-dimensional PET scans, the motion distance did not affect VRC (P>0.05), whereas VRC decreased with increasing distance in three-dimensional PET scans (P<0.05).
  Conclusion: The threshold value (x+3×SD) had the potential to delineate the ITV of cancerous tissues, surrounded by lung tissues, particularly in two-dimensional PET images.    
   
• انتشار مقاله: 14-03-1394
• نویسندگان: Yangchun Chen,Xiangrong Chen,Ji-an Liu,Fanyong Li
• مشاهده