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- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: risk factors,Lung cancer,Coffee,cohort
- چکیده:
- چکیده انگلیسی: Background: Lung cancer is a major cause of cancer death worldwide. The incidence of lung cancer in Thailand increasing, but risk factors are rarely reported. Objective: To investigate the effect of coffee consumption on lung cancer in Thai population. Methods: Between 1990 and 2001, lifestyle and demographic data were collected from 24,528 participants in the Khon Kaen Cohort Study (KKCS), who were followed through 2016, by linking to the Khon Kaen Population-based Cancer Registry. A total of 12,668 eligible participants (68.8% females, mean age 51.0 years at baseline) having complete datasets (239,488 person-years of follow up with 138 incident cases of lung cancer observed) were analyzed using a multi-variable adjusted Cox proportional hazard models. Results: Coffee consumption was associated with reduced risk for lung cancer (adj. HR = 0.54; 95% CI: 0.35-0.84) after adjusting for age and gender. Cigarette smoking (adj. HR = 2.76; 95% CI: 1.32-5.78) and family history of cancer (adj. HR = 1.65; 95% CI: 1.10-2.48) were associated with higher risk. Conclusion: This study suggests coffee consumption may be a protective factor for lung cancer in among this cohort.
- انتشار مقاله: 29-02-1399
- نویسندگان: Wongklang Kudwongsa,Supannee Promthet,Krittika Suwanrungruang,Anakapong Phunmanee,Patravoot Vatanasapt
- مشاهده
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: Colorectal cancer,Health Insurance,relative survival
- چکیده:
- چکیده انگلیسی: Background: Evidence from healthcare studies demonstrates that patients’ health insurance affects service
accessibility and the outcome of treatment. However, assessment on how colorectal cancer survival relates to health
insurance is limited. Objective: The study examined the association between health insurance and colorectal cancer
survival in Khon Kaen, Thailand. Methods: The retrospective cohort study was conducted with 1,931 colorectal cancer
patients from Khon Kaen cancer registry between January 1, 2003 and December 31, 2012, and was followed-up until
December 31, 2015. Relative survival was used to estimate the survival rate. Cox proportional hazard regression was
used to estimate the relationship between health insurance and colorectal cancer survival, represented with the hazard
ratio. Result: Most of the participants were males, and the median age was 62 years. The median survival time was
2.25 years (95% CI: 2.00-2.51). The five-year observed survival rate and relative survival rate were 36.87 (95% CI:
34.66-39.08) and, 42.28 (95% CI: 39.75-44.81), respectively. The factors that showed significant associations with
poorer survival after adjustment for gender and age were non-surgical treatments (HRadj=1.88;95%CI=1.45-2.45),
advanced stage (III+IV) (HRadj=2.50; 95%CI=2.00-3.12), histological grading in poorly differentiated (HRadj=1.84;
95%CI=1.32-2.56), and Universal Coverage Scheme (HRadj=1.37;95%CI=1.09-1.72). Conclusion: The survival of
colorectal cancer patients in the Universal Coverage Scheme was likely to be poorer than in the Civil Servant Medical
Benefit Scheme. This indicates an urgent need for a national program for colorectal cancer screening in the general
population and access to health insurance.- انتشار مقاله: 26-09-1397
- نویسندگان: Surachai Phimha,Supannee Promthet,Krittika Suwanrungruang,Jarin Chindaprasirt,Prachak Bouphan,Chalongpon Santong,Patravoot Vatanasapt
- مشاهده
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: Breast cancer,Breast cancer awareness,B-CAS,Thai women
- چکیده:
- چکیده انگلیسی: Background: Breast cancer is the most common cancer in women worldwide. In south-east Asia, both the incidence
and mortality rates of breast cancer are on the rise, and the latter is likely due to the limited access to large-scale
community screening program in these resource-limited countries. Breast cancer awareness is an important tool which
may, through increasing breast self-examination and the seeking of clinical examination, reduce breast cancer mortality.
Investigating factors associated with breast cancer awareness of women is likely to help identify those at risk, and
provide insights into developing effective health promotion interventions. Objective: To investigate factors associated
with breast cancer awareness in Thai women. Methods: A cross-sectional sample of Thai women aged 20-64 years
was collected during August to October, 2015 from two provinces of southern Thailand (Surat Thani and Songkla). A
questionnaire including the Breast Cancer Awareness Scale along with demographic characteristics was administered
and Proportional Odds Logistic regression was then used to investigate factors associated with breast cancer awareness.
Results: In total, 660 Thai women participated in this study. Factors most often associated with the various breast
cancer awareness domains were age and rurality. While rural women had poorer knowledge of breast cancer signs and
symptoms, they also had lower levels of perceived barriers and considerably better breast cancer awareness behaviors.
Conclusion: Despite lower knowledge of breast cancer risk factors and no evidence of better knowledge of signs and
symptoms, we found rural Thai women had considerably better breast cancer awareness behavior. This may be due to
these women’s lower levels of perceived barriers to breast cancer screening services. Indeed this suggests, at least in
Thai women, that interventions aimed at lowering perceived barriers rather than enhancing disease knowledge may
be more successful in engaging women with breast cancer screening services and increasing breast self-examination.- انتشار مقاله: 03-11-1397
- نویسندگان: Cameron Paul Hurst,Supannee Promthet,Nitchamon Rakkapao
- مشاهده
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: Breast cancer,Breast Cancer Screening,Indonesian Women
- چکیده:
- چکیده انگلیسی: Background: Globally, breast cancer is the second most common cancer in women and is a leading cause of mortality
in Indonesia. Raising awareness of breast cancer is particularly important to help at risk women seek medical treatment
for this disease. This study aimed to comprehensively investigate the Indonesian women’s level of knowledge about
breast cancer risk factors, barriers, attitude and breast cancer screening. Methods: This population-based cross-sectional
study administered the breast cancer awareness Indonesian scale (BCAS-I) to 856 Indonesian women. Samples were
selected in rural and urban combinations from three provinces by stratified random sampling. The ordinal logistic
model was used to investigate the clustering effect of the participant’s characteristics in this study. Results: Of the
women, 62% lived in rural areas and 38% lived in urban areas. Living in an urban area was significantly associated
with a lower knowledge of the risk factors. However, living in an urban area was significantly associated with better
attitudes and healthier behaviours related to breast cancer awareness. Women with higher education levels had 70%
worse attitudes toward breast cancer awareness. Women living South of Sumatera, women living in Yogyakarta, and
unmarried women were 5.03, 3.84, and 1.56 times as likely to have higher perceived barriers, respectively. Conclusion:
Urban women had a poorer level of knowledge of breast cancer risk factors compared to women living in more rural
areas. The result of this study may reflect inadequate breast cancer awareness campaigns or a lack of breast cancer
awareness campaigns. These findings suggest that additional education programs aiming to increase awareness and
educate the public are needed.- انتشار مقاله: 03-07-1397
- نویسندگان: Solikhah Solikhah,Supannee Promthet,Cameron Hurst
- مشاهده
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: Validation,Colorectal cancer screening literacy,Instrument development,Thai people
- چکیده:
- چکیده انگلیسی: Background: Colorectal cancer is an important public health problem worldwide. Although progress in screening
and treatment has considerably improved the prognosis in the developed world, in developing countries colorectal cancer
mortality rate remains relatively high. Colorectal cancer screening literacy is an important initial step in overcoming this
problem. Development of a validated assessment instrument is therefore important for implementation of appropriate
health education programs to facilitate early detection. Objectives: This study focused on generation and validation of
a colorectal cancer screening literacy scale for Thai people in northeastern Thailand. Methods: This methodological
study was carried out in two phases: (1) literature reviews and semi-structured interviews were used to select items,
then the content and face validity were checked; and (2) a confirmatory factor analysis (CFA) was conducted to test
construct validity and reliability. A self-administered questionnaire was used to collect data from Thai people aged 50-
65 in June 2017. Results: For the total of 400 participants who responded (response rate 100 %), the age ranged from
50 to 65 years old (mean = 57.3, SD = 4.616). The colorectal cancer screening literacy scale was designed to include
6 domains and it was shown to have good internal consistency, and CFA demonstrated the model to fit data adequately
(Chi-squared/degree of freedom = 1.079, p = 0.061, CFI = 1.00, GFI = 0.93, AGFI = 0.91, RMSEA = 0.014 and SRMR
= 0.036). The final version of its, consisting of 57 items across the 6 domains covering key aspects of colorectal cancer
screening literacy, demonstrated good psychometric properties for this population. Conclusions: Use of the colorectal
cancer screening literacy scale in Thai people could lead to improved educational programs for optimizing colorectal
cancer screening.- انتشار مقاله: 01-08-1397
- نویسندگان: Chontira Kawthaisong,Supannee Promthet,Supot Kamsa-Ard,Rujira Duangsong
- مشاهده
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: cervical cancer,time trend,population-based cancer registry data
- چکیده:
- چکیده انگلیسی: Background: Cervical cancer is the second most common cancer of women in Thailand. There have been no reports
of incidence and future in Khon Kaen, a province in northeastern Thailand, where the relatively high prevalence gives
evaluation of cervical cancer screening a high priority. Objectives: To determine cervical cancer incidence rates in
Khon Kaen for 1990–2014 and predict future trends until 2029. Methods: Cancer incidence data from the Khon Kaen
population-based cancer registry were analyzed and age-standardized incidence rates (ASR) were estimated. Joinpoint
analysis and age-period-cohort modeling were applied for data from 1990 to 2014 and the Nordpred package was
employed to project trends from 2015 to 2029. Results: Between 1990 and 2014, a total of 3,258 cases were diagnosed
with ICD-O code C53 (invasive cervical cancer). Before 2005, an annual percentage change (APC) varied widely, with
outliers in 1993 and 1999. The APC computed with the Joinpoint software decreased at -2.8% (95% CI;-4.5 to -1.1)
per year on average. After 2005, a rise was noted until 2008, after which a drop became apparent with an APC of
-8.0% (95% CI; -14.5 to -1.1) per year on average. Both period and cohort effects played a role in shaping the decrease
in incidence. The three projection method suggested that incidence rates would continue to decrease in the future.
Conclusions: A decreasing trend in incidence of cervical cancer in Khon Kaen was noted from 1990 to 2014 with a
prediction of continuous decrease until 2029. Maintenance and improvement of the screening program is advised.- انتشار مقاله: 25-07-1397
- نویسندگان: Thitima Saenrueang,Supannee Promthet,Supot Kamsa-Ard,Prasit Pengsaa
- مشاهده
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: Survival,Prognostic factors,menopausal status,Invasive breast cancer
- چکیده:
- چکیده انگلیسی: Background and Purpose: This study focused on molecular subtypes and prognostic factors for survival of preand
post-menopausal breast cancer patients. Methods: A retrospective cohort study was performed on 523 patients
with invasive carcinoma of the breast treated at Ubon Ratchathani Cancer Hospital,Thailand from 2002 to 2016.
Patient characteristics were collected based on a systematic chart audit from medical records. Prognostic factors were
performed by observe survival analysis. A Cox regression model was used to calculate hazard ratios of death, taking
into account the age and menopause status, molecular subtype, stage of disease, histological grade, lymphatic and
vascular invasion, resection margin, hormone receptor expression, and treatment modality. Results: The median time
from the diagnosis of invasive breast cancer to the last follow-up or death was 10.2 [95% CI = 9.28-11.95] years in
premenopausal women, and 7.4 [95% CI = 6.48-8.44] years in postmenopausal cases. The overall survival estimates
at 5 and 10 years for younger woman of 71.2% and 51.8% respectively, appeared slightly better than the 68.3% and
40.9% for postmenopausal women [HRadj = 1.27, 95% CI =0.99-1.63]. In the multivariate analysis, 3 prognostic
indicators significantly predicted a worse overall survival in premenopausal patients, triple negative subtype [HRadj =
6.03, 95% CI = 1.94-18.74], HER2-enriched status [HRadj = 4.11, 95% CI = 1.59-10.65] and stage III [HRadj = 2.73,
95% CI = 1.10-6.79]. Statistically significant increased risk of death in postmenopausal patients was noted for only
chemotherapy after mastectomy [HRadj = 8.76, 95% CI = 2.88-26.61], and for a Luminal B status [HRadj = 3.55, 95%
CI = 1.47-8.53]. Conclusion: Postmenopausal women with invasive breast cancer experience a significantly shorter
survival than do their premenopausal counterparts. The predictors of worse overall survival were molecular subtype,
stage of disease and type of treatment administered.- انتشار مقاله: 24-12-1396
- نویسندگان: Sopit Tubtimhin,Supannee Promthet,Krittika Suwanrungruang,Pongsatorn Supaattagorn
- مشاهده
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: Colorectal cancer,Red meat consumption,fecal immunochemical test
- چکیده:
- چکیده انگلیسی:
Background: There is convincing evidence from epidemiological studies that meat consumption increases colorectal cancer (CRC) risk. However, assessment of any association with a positive fecal immunochemical test (FIT) in CRC screening has been limited. If a link could be shown this might be helpful for establishing a risk group for colonoscopy. Objective: This study aimed to assess any association between meat consumption and other lifestyle factors and a positive FIT result in a Thai population. Methods: A cross-sectional analytical study was conducted with 1,167 participants in a population-based randomized controlled trial. CRC was screened from May 2016 - February 2017. Subjects aged 45-74 years who met the eligibility criteria were randomly allocated to the study arm. A positive FIT was determined with cut-off 100 ng/mL. Multiple logistic regression was used to analyze any relationship between lifestyle factors and a positive FIT. Result: The total number of subjects was 1,060 (90.8% return rate of FIT). With FIT100, FIT150, and FIT200, positive tests were found in 92 (8.68%), 74 (6.98%), and 60 (5.66%), respectively. No significant associations were noted with any of the variables, except for being aged 60-74 years (ORadj = 1.62, 95% CI: 1.03-2.54) Borderline significance was observed for high consumption of vegetables (ORadj = 0.62, 95% CI: 0.36-1.07) and being male (ORadj = 1.39, 95% CI: 0.87-2.22). Conclusion: Despite the evidence from the literature, no association was here found between a positive FIT result and meat consumption or other well-established lifestyle parameters. Being aged 60-74 years was a risk factor which should be taken into account in CRC screening strategy in countries like Thailand with limited access to endoscopy.- انتشار مقاله: 16-08-1396
- نویسندگان: Putthikrai Pramual,Pongdech Sarakarn,Siriporn Kamsa-ard,Chananya Jirapornkul,Naowarat Maneenin,Prasert Thavondunstid,Prachak Juntarach,Supannee Promthet
- مشاهده