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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Iranian Journal of Neonatology
- نوع مقاله: Journal Article
- کلمات کلیدی: neonate,Juvenile idiopathic arthritis,Chronic arthritis
- چکیده:
- چکیده انگلیسی: Background: A common type of chronic arthritis in children and adolescents is juvenile idiopathic arthritis (JIA).
According to the International League of Associations for Rheumatology (ILAR) classification, JIA diagnostic criteria include age under 16 years and disease duration of six-weeks. Based on the number of involved joints in the first sixmonths of disease onset, JIA is categorized into oligoarticular or polyarticular subtypes. Age is a characteristic factor in the diagnosis of disease subsets; it is worth mentioning that cases younger than six months of age are seldom found in any of the subtypes. Case report: In this report, we present a rare case of JIA in an infant, presenting at 20 days of age. Effusion of the right hip joint was one of the primary manifestations of the disease. During hospitalization, she went through sepsis workup and a four-week antibiotic therapy for management of lower limb pseudoparalysis. In spite of antibiotic therapy, she developed effusion of a second joint. According to the course and duration of symptoms and ILAR classification for
JIA, oligoarticular JIA was diagnosed and treated.
Conclusion: In this case, infectious diseases, such as tuberculosis and brucellosis, and malignancies were ruled out as a cause of inflammation through bone marrow aspiration, culture, and tests; ultrasound and magnetic resonance imaging showed no lytic and sclerotic lesions or a fracture. Our experience showed a rare case of JIA and suggested that JIA must be considered in children with joint inflammation at any age- انتشار مقاله: 30-03-1396
- نویسندگان: Abdolreza Malek,Mohammad-Saeed Sasan,Narges Afzali,Somayeh Ghahremani,Sara Ghahremani
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: children,Pneumonia,Cyanosis-Tachypnea,Zinc sulfate
- چکیده:
- چکیده انگلیسی:
Background: Acute respiratory infections and especially pneumonia are considered as the most important infection-induced cause of child mortality in developing countries. We aimed to investigate the effect of prescribing zinc sulfate on improving the clinical symptoms of pneumonia in 2-59-month-old children.
Materials and Methods: This clinical trial study was performed on 108 children complaining of fever, coughs, and tachypnea referring to three educational hospitals of Mashhad (Ghaem, Imam Reza, and Dr. Sheikh). The patients were randomly assigned into control (n=54), and intervention (n=54). In the control group placebo was prescribed, while the intervention group received oral zinc sulfate 10 mg (1 ml/ kg in children younger than one year, and 20 mg/kg for children above one year every 12 hours. During hospitalization, every 12 hours the clinical symptoms of both groups including tachypnea, duration of fever, coughs, intercostal retraction, hypoxia, crackles-wheezing, and duration of hospitalization were recorded. At the beginning and end of the treatment, two blood samples were taken for determining the serum level of zinc.
Results: The findings indicated that the serum level of zinc sulfate after the intervention increased significantly in the intervention group (p <0.001). There was a significant difference in the duration of fever between the intervention and control groups 24 hours after hospitalization (p=0.014) and 36 hours post-hospitalization (p=0.02). Comparing the presence or absence of tachypnea in the intervention and control groups, there was a significant difference at 36 hours post-hospitalization (p=0.02).
Conclusion: Based on the results, zinc supplement was effective for patients with pneumonia in reducing the duration of fever and number of breaths, but it had no significant effect on the duration of coughs and hospitalization.- انتشار مقاله: 02-02-1399
- نویسندگان: Farhad Heydarian,Mona Nasiri,Ali Reza Attaei Nakhaie,Hamid Ahanchian,Somayeh Ghahremani,Ali Haghbin,Sarah Ghahremani
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: Pregnancy,Growth,Cell phone,Magnetic Fields,Preterm Labor
- چکیده:
- چکیده انگلیسی: Background
Low birth weight is one of the most important health indicators in evaluating pregnancy care worldwide. We aimed to evaluate the effect of cell phones used in pregnancy on fetal growth and preterm labor.
Materials and Methods
The search process included screening the relevant articles on electronic databases of Scopus, EMBASE, Cochrane, Web of Science, and Medline to analyze the association of maternal exposure to magnetic fields with fetal growth, birth weight, small-for-gestational-age (SGA), and preterm labor.
Results
In the first study, the duration of pregnancy was shorter for mothers using cell phones for more than one hour per day than those use shorter than one hour. In the second study, the intermediate use of cell phones by mothers indicated an increased risk of preterm birth. In the third study, the birth weight were lower in excessive cell phone users than normal status. In the fourth study, low, medium, and high cell phone exposure during the six months before conception had no effect on low birth weight, preterm birth, and SGA.In the fifth study, a negative correlation was observed between magnetic fields expose during pregnancy and the birth week, birth weight, and birth length of the newborn. In the sixth study, the risk of low birth weight, preterm birth, and SGA was close to null. In the seventh study, dental radiography during pregnancy was associated with low birth weight, specifically with term low birth weight.
Conclusion
In general, there are contradictory findings on the impact of cell phone exposure during pregnancy. These results should be interpreted with caution because of the small sample size and recall bias.- انتشار مقاله: 01-02-1399
- نویسندگان: Zahra Khojastehfard,Somayeh Ghahremani,Maryam Sabaghian,Samaneh Ghalebizadeh,Zoleykha Asgarlou,Soheil Mohammadi Yazdi,Mahla Salarfard
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: Factor analysis,Systematic review,Postpartum Bonding Questionnaire
- چکیده:
- چکیده انگلیسی: Background
Postpartum Bonding Questionnaire (PBQ) is a remarkable tool to assess impairments in the mother-infant bonding. The purpose of the present study was to review the factorial structure of the PBQ cross different versions.
Materials and Methods
The search strategy was implemented on databases of Medline (via PubMed), Scopus, Cochran library and Web of Science through electronic databases. The quality assessment was fulfilled by COSMIN checklist.
Results: The four factors were identified in original English version of PBQ. Theses consisted of "impaired bounding", "rejection and anger", "anxiety about care of the baby", and "risk of abuse". Three-factor-solution was confirmed by other English versions. In the Italian version of PBQ, three factors emerged including "annoyance and anger toward the infant", "detachment and rejection" and "anxiety about infant care". In the Spanish version of the PBQ, four factors including "impaired bonding", "anxiety about care", "lack of enjoyment and affection for the baby", and "rejection and risk of abuse". Three studies assessed factorial structure of Japanese version of PBQ. In the first Japanese version, four factors with 14 items were emerged including "impaired bonding ", "rejection and anger" and "anxiety about care", and "lack of affection". In second adapted Japanese version, exploratory factor analysis (EFA) identified a three factor solution: "mother's annoyance with anger toward their baby", "lack of affection" and" rejection and fear". The third version identified one-single solution. In the German version, one single factor emerged that explained 31 of the total variance.
Conclusion
Original English version of PBQ was not confirmed in Japanese, Italian, Spanish and other English versions.- انتشار مقاله: 24-08-1397
- نویسندگان: Sarah Ghahremani,Hossein Aryan,Somayeh Ghahremani,Forough Rakhshanizadeh,Rahele Rahimi,Masumeh Ghazanfarpour
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: children,corticosteroid,Coronary artery lesions,Kawasaki
- چکیده:
- چکیده انگلیسی: Background
Kawasaki Disease (KD) is a vasculitis with multi-organ involvementof unknown etiology; it is the most common cause of pediatric-heart diseases in developed countries. Treatment with Intravenous Immunoglobulin (IVIG) prevents coronary artery lesions; although there are some IVIG-resistant cases, combination therapy with corticosteroids and IVIG is one of the recommendations for treatment of these cases. The aim of this study was to compare these three options for treatment of Kawasaki Disease and to evaluate their ability to deal with coronary artery complication of Kawasaki Disease.
Materials and Methods
A prospective cross- sectional study of hospitalized cases of Kawasaki Disease, conducted in pediatric department of Imam Reza hospital, Mashhad-Iran, during 2013 to 2015 (18 months). Based on demographic and clinical data of these patients, children with high risk of unresponsiveness to IVIG therapy (based on Harada score), were determined and treated with IVIG and corticosteroids- combination initially. Follow-up patients for heart complications were 6 weeks.
Results
Twenty five patients (89.2%) out of total 28 hospitalized patients in this period of time who fulfilled diagnostic criteria were considered as complete Kawasaki Disease. Coronary Artery Lesions (CALs) were shown in 4 patients during the follow-up period, with high risk in patients with incomplete presentation (33.3% versus 12%, P<0.05). None of the children were treated with IVIG and corticosteroids combination therapy at the onset showed coronary artery lesions.
Conclusion
The current study showed that IVIG plus intravenous methylprednisolone (IVMP) combination therapy is a safe and effective treatment regimen in prevention of CALs.- انتشار مقاله: 08-04-1395
- نویسندگان: Abdolkarim Hamedi,Sarah Ghahremani,Abdolreza Malek,Somayeh Ghahremani,Alireza Ataei Nakhaei
- مشاهده
- جایگاه : پژوهشی
- مجله: Asia Pacific Journal of Medical Toxicology
- نوع مقاله: Journal Article
- کلمات کلیدی:
- چکیده:
- چکیده انگلیسی:
- انتشار مقاله: 06-03-1395
- نویسندگان: Abdolkarm Hamedi,Alireza Ataei,Mohammad Reza Balali,Somayeh Ghahremani,Sarah Ghahremani
- مشاهده
- جایگاه : پژوهشی
- مجله: Asia Oceania Journal of Nuclear Medicine and Biology
- نوع مقاله: Journal Article
- کلمات کلیدی: Nuclear Medicine,Meningioma,TRODAT,Parkinsonism
- چکیده:
- چکیده انگلیسی: We reported a 71 years old woman, with history of rest and postural tremor, bradykinesia and memory problems. In her dynamic MRI, a contrastenhanced tumor in the cerebellopontine (CP) angle was found which was compatible with a meningioma. 99mTc-TRODAT SPECT showed decreased activity in the left putamen, indicating idiopathic Parkinson disease. There was also a focus of increased activity on the right side of the skull base, which was compatible with meningioma in MRI.
- انتشار مقاله: 29-11-1396
- نویسندگان: Ramin Sadeghi,Mahsa Sabour,Ali Shoeibi,Somaye Ghahremani
- مشاهده
- جایگاه : پژوهشی
- مجله: Asia Oceania Journal of Nuclear Medicine and Biology
- نوع مقاله: Journal Article
- کلمات کلیدی: Tablet splitting,Differentiated thyroid cancer, TSH, Levothyroxine, suppressive therapy
- چکیده:
- چکیده انگلیسی: Objective(s): TSH suppression by Levothyroxine consumption is a mainstay of thyroid cancer treatment. Tablet-splitting is a worldwide approach in dose adjustment in patients. However, it is highly recommended to evaluate the validity of tablet splitting for each distinctive drug by clinical trials before routinely using tablet halves in clinical practice. In this study we compared the effect of 150 μg dose of Levothyroxine by use of a100 and a 50 μg tablets or one and half 100 μg tablets in Differentiated thyroid cancer (DTC) patients.
Methods: One hundred DTC patients treated with one and half 100 μg Levothyroxine tablets were randomly divided into two groups. The first group continued taking medication as before and the second group received the same daily dose by taking one 100 and one 50 microgram Levothyroxine tablets. The mean changes in TSH and T3 levels and patients weight were compared between the groups.
Results: 91 patients completed the study. Levothyroxine consumption pattern, age, gender distribution, weight and TSH levels were comparable between groups at the beginning of the study. The mean change of body weights, serum levels of T3 and TSH showed no significant difference between groups in different time points during the study (P>0.05).
Conclusion: This study showed similar efficacy of tablet splitting and two tablets administration for Levothyroxine; however, patients preferred two tablets at the end of the study. It can be concluded that tablet splitting can be used as an alternative way when the 50 μg tablet is not available.- انتشار مقاله: 18-07-1396
- نویسندگان: Ramin Ashrafpour,Narjess Ayati,Ramin Sadeghi,Samira Zare Namdar,Nayyereh Ayati,Somaye Ghahremani,Seyed Rasoul Zakavi
- مشاهده