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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Journal of Dental Materials and Techniques
- نوع مقاله: Journal Article
- کلمات کلیدی: Quality of Life,Oral health,Oral manifestation,geriatric dentistry
- چکیده:
- چکیده انگلیسی: Introduction: The incidence of oral and dental lesions increases with age, which can negatively affect the quality of life.The aim of this study was to evaluate the oral and dental status, oral health-related quality of life (OHRQoL), and the associated factors in a population of institutionalized elderly in Southeast Iran. Methods: This cross-sectional study was conducted on 90 institutionalized elderly who were 60 years old or older. Oral examinations were carried out using mirror and probe under proper light. In addition to recording oral lesions, the dental status of the elderly was determined according to the WHO’s criteria. The geriatric oral health assessment index (GOHAI) questionnaire was used to determine OHRQoL. Factors such as age, gender, education, smoking, systemic disease, and the use of denture were recorded for each participant. Data were analyzed by appropriate statistical tests using SPSS software. Results: Forty three percent of the participants had oral conditions. Fissured tongue was the most common oral lesion. The prevalence of oral lesions in females was more than twice that of males (p <0.001). The mean DMFT was 25.6±7.3, and no relationship was found between DMFT and age, gender, education, smoking or systemic diseases (P>0.05). The mean GOHAI in the elderly was 42.8±9.7. Smoking and the presence of oral lesions significantly decreased OHRQoL (p <0.05). Conclusion: The oral and dental status and consequently OHRQol of the elderly were relatively poor. The need for planning to promote the oral and dental health care aiming at improving the quality of life should be emphasized in this region.
- انتشار مقاله: 15-10-1398
- نویسندگان: Shirin Saravani,Hamideh Kadeh,Shahram Arbabi
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Dental Materials and Techniques
- نوع مقاله: Journal Article
- کلمات کلیدی: Human Immunodeficiency Virus,Risk Factor,Oral lesions,Acquired immunodeficiency syndrome,Oral manifestation
- چکیده:
- چکیده انگلیسی: Introduction: Oral manifestations can be the first signs of human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) and a useful marker for the progression of this disease. The present study aimed to determine the prevalence of oral manifestations and examine their relationship with socio-demographic factors in HIV-positive patients in the health centers affiliated to Zahedan University of Medical Sciences (Southeast Iran). Methods: In this cross-sectional study in addition to determining oral manifestations based on the classification of EC-clearing house (European Commission clearing house), information such as age, gender, marital status, residence, education, occupation, habits, oral hygiene, loss of weight in the last six months. Body Mass Index (BMI), mode of HIV transmission, stage of disease, anti-retroviral therapy (ART), and duration of HIV were gathered through direct question from the patients or the information contained in their records. Then the relationship between various factors and oral manifestations was analyzed using Chi-square, Fisher’s Exact Test, Student T Test, Mann- Whitney tests and logistic regression. Results: Oral examination was performed on 119 HIV-positive patients who were 69.7% male and 30.3% female and had a mean age of 35.4±12.7 years. Oral manifestations were found in 57.1% of the patients. Pseudomembranous candidiasis (34.1%) and linear gingival erythema (33%) were the most common lesions in these patients. The probability of oral manifestations occurrence increased with age and duration of smoking in smokers with HIV (P=0.036 and P=0.012, respectively). Conclusion: Most oral manifestations were those strongly associated with HIV infection (91%). Timely diagnosis and treatment of oral manifestations in HIV patients should be considered in conjunction with other treatments.
- انتشار مقاله: 06-05-1395
- نویسندگان: Shirin Saravani,Tahereh Nosratzehi,Sarvar Mir
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Dental Materials and Techniques
- نوع مقاله: Journal Article
- کلمات کلیدی: oral pathology,Elderly,Epidemiologic study
- چکیده:
- چکیده انگلیسی: Introduction: As a result of aging process, oral mucosa becomes susceptible to oral diseases. Having knowledge about prevalence and distribution of geriatric oral diseases is essential for prevention and treatment planning. This study aimed to evaluate the prevalence of geriatric patients’ oral biopsies in specimens obtained in medical centers of Zahedan University of Medical Sciences. Methods: This cross-sectional study was conducted on 2496 cases of biopsied oral lesions found in pathology archive of medical centers of Zahedan University of Medical Sciences throughout a 20-year period. Information about age, gender, lesion location and type of oral lesions of patients over 60 years old were collected and analyzed using SPSS software. Results: In this cross-sectional study, 412 (16.5%) biopsy samples were taken from patients over 60 years old. Most subjects were in their seventh decade (59.5%), male (56.1%) and soft tissue (96.6%). Two hundred and sixty (63.1%) cases were neoplastic lesions and 152 (36.9%) were non-neoplastic. There was no significant relationship between the type of lesions (neoplastic and non-neoplastic) and age, gender and their location. The most prevalent lesions were oral squamous cell carcinoma (42.5%), non-specific inflammatory lesions (7.8%), irritation fibroma (3.4%) and oral verrucous carcinoma (3.4%). Conclusion: Since the malignant lesions were the most common oral lesions in the studied geriatric patients, oral health care must be prioritized in the general health policies.
- انتشار مقاله: 02-03-1395
- نویسندگان: Shirin Saravani,Marziyeh Moudi,Hamideh Kadeh,Mahya Tavakoli Amin
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Dental Materials and Techniques
- نوع مقاله: Journal Article
- کلمات کلیدی: Clinical Diagnosis,oral manifestations,Histopathologic Diagnosis
- چکیده:
- چکیده انگلیسی: Introduction: Different oral lesions have clinical characteristics which in some cases are similar. Therefore, in these cases histopathological examination for correct diagnosis is necessary. The aim of this study was to evaluate the compatibility rate of clinical and histopathological diagnosis of oral lesions in Zahedan School of dentistry. Methods: In this retrospective study, determination of the compatibility of clinical and histopathological diagnosis was done using 631 available records in department of pathology, Zahedan School of dentistry, during 1999- 2015. Type of the lesions (neoplastic and non-neoplastic), and demographic data including age, gender, location of lesions (intraosseous or soft tissue), and clinician’s specialty was extracted from patients records and data were analyzed using SPSS (V.21) software and Chi- Square test. Results: Total compatibility rate between clinical and histopathological diagnosis was 70.1%. The most accurate clinical diagnosis was related to lichenoid lesions (100%) and leukoplakia (100%) and verrucous carcinoma had the least diagnostic compatibility (20%). There was no significant relationship between compatibility of histopathological and clinical diagnosis with age range, gender, location, and clinician’s specialty. Also non-neoplastic lesions with compatible histopathological and clinical diagnoses were three times more than neoplastic lesions. (P=0.03). Conclusion: Although there was a great compatibility between clinical and histopathological diagnosis, many records had no clinical diagnosis and the inconsistency was also significant. Therefore, more attention to clinical signs and effective cooperation between the clinician and pathologist for correct and more accurate diagnosis and treatment is recommended
- انتشار مقاله: 29-11-1394
- نویسندگان: Shirin Saravani,Mahya Tavakoli Amin,Hamideh Kadeh
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Otorhinolaryngology
- نوع مقاله: Journal Article
- کلمات کلیدی: oral cavity,Soft tissue,Pyogenic Granuloma,Fibroma
- چکیده:
- چکیده انگلیسی: Introduction:
Peripheral reactive lesions of soft tissue are common oral lesions that dentists face during routine examinations. Diagnosis and development of a treatment plan is difficult if dentists are not aware of the prevalence and clinical symptoms of these lesions. The frequency of these lesions differs across various populations. The aim of this study was to determine the frequency and distribution of oral reactive lesions over a period of 7 years (2006–2012).
Materials and Methods:
In this retrospective study, available records from the archives of the Department of Pathology, Dental School and the two main hospitals in southeast of Iran (Zahedan) over a period of 7 years (2006–2012) were reviewed. Information relating to the type of reactive lesion, age, gender and location was extracted and recorded on data forms. Data were analyzed using SPSS statistical software (V.18) using the chi-square and Fisher’s exact test.
Results:
Of 451 oral lesions, 91 cases (20.2%) were reactive hyperplastic lesions. The most common lesions were pyogenic granuloma and irritation fibroma, respectively. These lesions were more frequent in women (60%) than men (40%). The most common locations of involvement were the gingiva and alveolar mucosa of the mandible, and lesions were more common in the 21–40-year age group. The relationship between age group and reactive lesions was statistically significant (P=0.01).
Conclusion:
The major findings in this study are broadly similar to the results of previous studies, with differences observed in some cases. However, knowledge of the frequency and distribution of these lesions is beneficial when establishing a diagnosis and treatment plan in clinical practice.- انتشار مقاله: 29-11-1392
- نویسندگان: Hamideh Kadeh,Shirin Saravani,Mohammad Tajik
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: children,Quality of Life,Beta-Thalassemia,dmft index
- چکیده:
- چکیده انگلیسی: Background: b-thalassemia major is a common hereditary blood disease that can affect patients’ oral health and quality of life. The present study aims to determine the relationship between health of deciduous teeth and the Oral Health-Related Quality of Life (OHRQoL) in children diagnosed with β-thalassemia major compared with healthy children.
Materials and Methods
This cross-sectional study was performed on 50 children diagnosed with β-thalassemia major and 50 healthy children aged 3-6 years old. Decayed, missing, and filled teeth (dmft) of the participants were measured according to the World Health Organization (WHO) criteria and the OHRQoL with the Early Childhood Oral Health Impact Scale (ECOHIS). Data were analyzed using SPSS software version 19.0.
Results: The results showed that the dmft index of the patient group with a mean of 5.36 was significantly higher than the healthy group with a mean of 3.36. The mean OHRQoL in the patient group (19.24) was significantly higher than that of the healthy group (11.24). The mean dmft had a significant positive relationship with the ECOHIS score of the children with thalassemia major (r=0.769, p=0.000), and healthy children (r=0.756, p=0.000).
Conclusion: According the results, the positive correlation between the dmft index and the mean OHRQoL indicated that dental problems in most children with β-thalassemia major are associated with a poorer OHRQoL. Since the dmft index and ECOHIS were higher among children diagnosed with β-thalassemia major, the prevention and treatment of dental problems seem necessary for improving their quality of life.- انتشار مقاله: 07-06-1397
- نویسندگان: Foroogh Amirabadi,Shirin Saravani,Ghasem Miri-Aliabad,Mahnaz Khorashadi-Zadeh
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: children,adolescents,Oral biopsy,Oral lesions
- چکیده:
- چکیده انگلیسی: Introduction
The frequency of pediatric and adolescent oral and maxillofacial lesions is various in different societies. The present study aimed at investigating the frequency of oral and maxillofacial pediatric and adolescent biopsies in Zahedan (southeast Iran), and compare the results with other epidemiologic studies.
Methods and Materials
This retrospective study reviewed oral and maxillofacial lesions in patients with 0-18 years old referring to the treatment centers of Zahedan University of Medical Sciences during 12-years period. Patients’ demographic information including age, gender and location of the lesion were collected and statistically analyzed.
Results
In general, among 1112 oral and maxillofacial lesions, 154 (13.9%) cases were related to children and adolescents younger than 18 years old. The average age of patients was 11.4 ± 4.9, 53.2% and 46.8% of them were boys and girls, respectively. The most frequent sites of lesions were the gingiva and lip. The most prevalent lesions included inflammatory/reactive, cystic and neoplastic lesions, respectively. Benign and malignant tumors comprised 12.3% and 4.5% of cases. Moreover, pyogenic granuloma and peripheral giant cell granuloma (PGCG) were the most frequent lesions.
Conclusion
The most prevalent oral and maxillofacial lesions in patients under 18 years old were inflammatory/reactive lesions in gingiva and in the 13-18 age range. Determining the characteristics of these lesions in the children and adolescents population provides a firm groundwork for proper diagnosis and treatment.- انتشار مقاله: 02-10-1393
- نویسندگان: Shirin Saravani,Hamideh Kadeh,Foroogh Amirabadi,Narges Keramati
- مشاهده
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: Squamous Cell Carcinoma,Glutathione S-transferase T1,Glutathione S-transferase M1
- چکیده:
- چکیده انگلیسی: Background: The role of genetic polymorphisms in genes of Glutathione-S-transferases (GST) enzymes in susceptibility
to oral cavity cancers is controversial. Oral Squamous Cell Carcinoma (OSCC) is the most common oral cavity neoplasm.
Aimed to evaluate the potential impacts of two well-known null variants residing in the gene encoding GSTM1 and
GSTT1 enzymes of OSCC patients in the southeast of Iran. Methods: In a case-control design, 113 individuals (50
OSCC patients, and 63 healthy subjects) were included. DNA was extracted using paraffin-embedded tissues. GST
genotyping was carried out using multiplex PCR. Results: In 113 participants, 41 (36.3%) and 72 (63.7%) were males
and females respectively. No significant difference was recognized for distribution of GSTM1 (P=0.11) and GSTT1
(P=0.28) null genotypes between OSCC patients (58%, and 24% respectively) and healthy controls (42.9% and 15.9%
respectively). Also, no significant difference was noted regarding the frequency of GSTM1 null genotype in different
histological grades, however, those patients with more aggressive disease (poorly differentiated or grade III) revealed
with a significantly higher ratio (66.7%) of GSTT1 null genotype (P=0.002). The highest odds ratio for OSCC was related
to combined null genotypes for GSTM1 and GSTT1 (OR=2.5, 95% CI: 0.7-9.2), however, this was not statistically
significant finding (P=0.15). Conclusion: Null genotypes polymorphisms were more common in OSCC than healthy
individuals. GSTT1 null genotype may be an important genetic factor in the progression of OSCC.- انتشار مقاله: 27-02-1397
- نویسندگان: Shirin Saravani,Masoud Miri-Moghaddam,Ali Bazi,Ebrahim Miri-Moghaddam
- مشاهده