در هنگام جستجو کلمه در قسمت عنوان میتوانید کلمات مورد جستجو را با کاراکتر (-) جدا کنید.
کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Evidence Based Care Journal
- نوع مقاله: Journal Article
- کلمات کلیدی: Quality of Life,Obesity,Psychometric,Checklist,Morbid,Review of literature
- چکیده:
- چکیده انگلیسی: Background: Since studies have demonstrated that morbid obesity can exponentially impair quality of life, the measurement of quality of life is paramount to monitoring the effects of treatment and influences the development of clinical pathways, service provision, healthcare expenditures, and public health policy. Accordingly, clinicians, researchers, and policy makers must rely on valid instruments.
Aim: This study aimed to review and critique the psychometric properties of some specific tools by COSMIN checklist and their application among morbidly obese individuals.
Method: We searched PubMed, Web of Science, PsycINFO, Ovid, Elsevier, and ScienceDirect by using the keywords related to the Quality of Life Questionnaire, namely “morbid obesity”, “tool”, and “scale”, to retrieve articles published during 1989-2017. Then, the psychometric properties of the selected tools were assessed using the COSMIN checklist.
Results: Most of the tools had not reported complete and desirable psychometrics properties. Demonstration of responsiveness from independent randomized controlled trials was not available in two of the eight questionnaires. These tools also did not report proper definition of interpretability. However, the data obtained by COSMIN checklist showed that Laval questionnaire is a proper scale for measuring quality of life in obese individuals, which can be recommended to researchers.
Implications for Practice: Although Laval questionnaire was found a proper tool for measuring the
quality of life among morbid obese patients, developing an instrument suitable for different societies with varied cultural and social characteristics is suggested because socio-cultural factors can influence the quality of life.- انتشار مقاله: 20-06-1396
- نویسندگان: Negar Yazdani,Farkhondeh Sharif,Nasrin Elahi,Abbas Ebadi,Seyed Vahid Hosseini
- مشاهده
- جایگاه : پژوهشی
- مجله: Research Journal of Pharmacognosy
- نوع مقاله: Journal Article
- کلمات کلیدی: Phytochemistry,Wallflower,Erysimum cheiri
- چکیده:
- چکیده انگلیسی: Wallflower (Erysimum cheiri (L.) Crantz) is a common medicinal plant in Persian medicine and nowadays some traditional products from wallflower are consumed on global markets. The aim of the present study was to study the phytochemical constituents of wallflower and discuss safety evaluations related to the traditional wallflower preparations. Major Persian scholars (e.g. Avicenna) books, Persian manuscripts (e.g. Makhzan-al-advia) and Arabic medical manuscripts (e.g Alshamel-fi alsanaat altebya) of the medieval Islamic era as well as current search engines including Pubmed, Scopus, Siencedirect, and Google Scholar were included in the study from 1700 up to 2018 A.D. In traditional medicine manuscripts, various topical and oral dosage forms of wallflower were administered in low doses. After renaissance, phytochemical investigations reported cardiac steroids in wallflower and it might be the reason that next medical investigations on the herb have been interrupted. According to in vivo studies, topical indications of cardiac steroids in doses lower than their inhibitory concentration 50 (IC50) should be safe and effective in some cutaneous disorders. Wallflower is reported to have several different classes of compounds including: 11 types of cardenolides (such as strophanthidin, bipindogenin, uzarigenin, cannogenol and digitoxygenin derivatives), two flavonoids, a cyanidin and two glucosinolates. Therefore, for safety guarantee, wallflower products require dose adjustment based on IC50 and probable cardenolide soluble content in that dosage forms.
- انتشار مقاله: 02-04-1397
- نویسندگان: Ghazaleh Mosleh,Parmis Badr,Amir Azadi,Zohreh Abolhassanzadeh,Seyed Vahid Hosseini,Abdolali Mohagheghzadeh*
- مشاهده
- جایگاه : پژوهشی
- مجله: Research Journal of Pharmacognosy
- نوع مقاله: Journal Article
- کلمات کلیدی: Persian Medicine,Wallflower,Erysimum cheiri,fissure in Ano
- چکیده:
- چکیده انگلیسی: Anal fissure is an ischemic ulcer that occurs in anoderm and it has no obvious etiology and pathophysiology in current medicine. Anal fissure has a profound history in Persian and Persian medicine and wallflower (Erysimum cheiri (L.) Crantz) has been a common medication in this case. Traditional oil and/or dilute decoction of wallflower has been introduced as an effective topical medicine for anal fissure in Persian medicine.The aim of this study was to demystify the ancient wisdom in administration of low-dose wallflower for anal fissure, via the view point of modern pharmacological mechanisms. The basic idea and source of information was according to Persian and Arabic medicine manuscripts of the medieval Islamic era. Electronic literature was searched for related phytochemical and pharmacological studies available in Scopus, Google scholar, Pubmed and ScienceDirect databases from 1900 to 2018. The results showed that different parts of wallflower contain several types of cardiotonic steroids, isothiocyanates and flavonoids. Low-dose topical cardiotonic steroids, below their IC50, could have potential effects on the ischemic condition of anal fissure ulcer and collagen synthesis in the local fibroblasts, by stimulation of Na+/K+ ATPase pump. Furthermore, other active compounds in wallflower are isothiocyanates that could be responsible for tissue protective effects by induction of NRf2 expression and activating TRPA1 channels. Also wallflower flavonoids are responsible for anti-inflammatory, analgesic and wound healing properties. To the best of our knowledge, this is the first time that low-dose topical wallflower administration is hypothesized to have anal fissure healing potential in conventional medicine. This study has introduced a novel mechanistic approach for anal fissure treatment.
- انتشار مقاله: 22-12-1396
- نویسندگان: Ghazaleh Mosleh,Parmis Badr,Zohreh Abolhassanzadeh,Seyed Vahid Hosseini,Abdolali Mohagheghzadeh,Amir Azadi*
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Medical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: Recurrence,Rectal Neoplasms,Survival,lymph node ratio,Cure model
- چکیده:
- چکیده انگلیسی: Background: Understanding the prognostic factors affecting the recurrence-free survival (RFS) of patients with rectal cancer (RC) is the mainstay of care. The present study aimed to identify factors affecting both short- and long-term RFS of patients with RC using semiparametric mixture cure models.
Methods: The data were obtained from the database of the Colorectal Research Center of Shiraz University of Medical Sciences, Shiraz, Iran, which was collected during 2007-2017. To determine the factors affecting recurrence, cure models were applied to short-term and long-term RFS of patients with RC separately. The cure rate was calculated using the smcure package in R 3.5.1 (2018-07-02) software. P- انتشار مقاله: 24-09-1397
- نویسندگان: Seyed Vahid Hosseini,Abbas Rezaianzadeh,Salar Rahimikazerooni,Leila Ghahramani,Alimohammad Bananzadeh
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Medical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: Hemorrhoids,Rectal Prolapse,recovery of function,Anorectal,Continent score
- چکیده:
- چکیده انگلیسی: Background: Stapled hemorrhoidopexy is a safe and acceptable alternative to traditional hemorrhoidectomy with shorter hospital stay, better satisfaction, and less postoperative pain. There have, however, been reports on early and late complications. Therefore, the present study was designed to assess the impact of stapled hemorrhoidopexy on anorectal function and continence. Methods: Sixty-one patients with rectal prolapse and/or symptomatic circumferential hemorrhoidal disease, as validated by the Wexner incontinence score, were included. Anal manometric indices were measured. The Wexner scores and anal manometric measures were compared pre- and postoperatively using the Mann–Whitney U test. (A P
- انتشار مقاله: 15-12-1395
- نویسندگان: Seyed Vahid Hosseini,Mehdi Tahamtan,Hajar Khazraei,Alimohammad Bananzadeh,Fahimeh Hajihosseini,Seyedeh Saeedeh Shahidinia
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Medical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: Rectal fistula,Surgical Flaps,Amniotic
- چکیده:
- چکیده انگلیسی: Background: Perianal fistula is a complicated disorder and most difficult to manage. New treatment methods would help surgeons to achieve a better outcome in patients with perianal fistula. Human amniotic membrane (HAM) has positive effects on wound healing in several conditions. The present study aimed to further determine the effect of HAM on wound healing of perianal fistula in rabbits.Methods: In a prospective experimental study, 14 male rabbits (aged 4-6 months and weighing 3-4 kg) were randomly divided into 2 groups. After 12 weeks, the high type perianal fistula was repaired with endorectal flap (ERF) and ERF plus HAM in the control and case groups, respectively. In all rabbits of the case group, a 1×1 cm width wrap of HAM was applied and fixed around the ERF site. Three weeks later, the repaired site of the perianal fistula was sent for pathologic wound healing scoring. The results were analyzed with the SPSS 21.0 software using Mann-Whitney test. Results: Six rabbits of each group survived the study period. There was a statistically significant difference in wound healing between the case and control groups (P<0.001). Wound healing process in the case group occurred better and faster than the control group.Conclusion: HAM has an effective role in enhancing the ERF procedure and considered appropriate. A combination of HAM with other methods is recommended.
- انتشار مقاله: 25-10-1395
- نویسندگان: Mohammad Rafati,Seyed Vahid Hosseini,Farid Moradian,Mozhdeh Zamani,Hajar Khazraei,Maral Mokhtari
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Medical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: Complications,Bariatric surgery,Gastrectomy,Single port
- چکیده:
- چکیده انگلیسی: AbstractBackground: In recent years, laparoscopic sleeve gastrectomy (LSG) has become more acceptable for obese patients. Single-port sleeve gastrectomy (SPSG) is more popular since each abdominal incision carries the risk of bleeding, hernia, and internal organ injury as well as exponentially affecting cosmesis. This cross-sectional study aimed at comparing multi-port sleeve gastrectomy (MPSG) and SPSG in terms of their early results and complications. Methods: Out of129 obese patients candidated for LSG, 102 patients were assigned to 2 groups of SPSG and MPSG. Complications and demographic data such as body mass index (BMI), age, gender, operation time, and hospital stay were measured. All surgeries were carried out between2013 and 2015 in Shiraz, Iran. Data analysis was performed using SPSS, version 16 for Windows (SPSS Inc., Chicago, IL). The continuous and categorical variables were compared using the Student t-test and the Chi-square test or the Fisher exact test, respectively. Results: The patients’ data from both groups were similar in terms of age, intraoperative and postoperative bleeding volume, and length of hospital stay. Mean BMI was 42.8±0.7 in the SPSG group and 45.3±1.2 in the MPSG group. Duration of surgery was significantly lower in the SPSG group (P<0.001). Only 1 patient from the SPSG group and 5 patients from the MPSG group had bleeding as an early complication.Conclusion: The differences in each complication between the groups were not statistically significant. SPSG seems to be safe and is the same as MPSG in terms of major postoperative complications.Trial Registration Number: IRCT201512229936N12
- انتشار مقاله: 10-09-1394
- نویسندگان: Seyed Vahid Hosseini,Seyed Ali Hosseini,Ahmed Mohammed Ali Hussein Al-Hury,Hajar Khazraei,Fatemeh Ganji,Fatemeh Sadeghi
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Medical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: Radiotherapy,Rectal Neoplasms,Human amniotic membrane,Colonic anastomosis,Anastomotic leak
- چکیده:
- چکیده انگلیسی: Background: Radiotherapy is one of the most important factors which results in negative effects on wound healing and increases anastomosis leakage. Diverting loop ileostomy has been usually performed after colorectal anastomosis in cases of colorectal cancer with a history of neoadjuvant radiotherapy to decrease the chance of leakage. Considering the side effects of diverting loop ileostomy, the objective of the present study is to investigate the effect of human amniotic membrane (HAM) on colorectal anastomosis leakage after neo-adjuvant radiotherapy. Methods: In this experimental animal study, 20 crossbreed rabbits were randomly divided into two groups (case group: 13 rabbits, control group: 7 rabbits) after receiving an equal dose of external beam radiation. Four weeks after irradiation, resection of 4 cm of colorectal segment and end-to-end single layer anastomosis were conducted. In the case group, a 2×2 cm wrap of HAM applied around the site of anastomosis. Eight weeks later, all the survived rabbits were sacrificed. A segment of anastomotic sites was resected in all expired and survived rabbits and sent for pathological evaluation. Mann-Whitney U Test (SPSS for Windows, Ver. 16, Chicago, IL) was applied to analyze healing scores between the two groups.Results: Due to anastomosis dehiscence, 5 rabbits expired in the control group, but all the 13 rabbits (case group) survived after 8 weeks and showed no leakage. In addition, pathological evaluation revealed significant epithelialization and neovascularization in the case group. Statistically, healing score was higher in the case group rather than the control group (P<0.001).Conclusion: To prevent post irradiation colorectal anastomosis leakage, the use of HAM might play a significant role and a feasible technical approach.
- انتشار مقاله: 13-04-1394
- نویسندگان: Sam Moslemi,Sajjad Ahmadi Joraghi,Reza Roshanravan,Leila Ghahramani,Mohammad Mohammadianpanah,Masood Hosseinzadeh,Abbas Rezaianzadeh,Ahmed Mohammed Ali Hussein,Neda Najibpour,Seyed Vahid Hosseini
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Medical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: Rectum,Reconstruction,Ileal pouch
- چکیده:
- چکیده انگلیسی: Background: The gold standard of the management of rectal cancer in the middle and lower parts is low anterior resection with coloanal anastomosis. About 50% of the patients undergoing this procedure might experience some complications because of the low capacity of the neorectum. The aim of this study was to evaluate ileal J-pouch interposition as a neorectum between the anal canal and the remaining colon in comparison to coloanal anastomosis and transverse coloplasty. Methods: Twelve dogs, weighing 23-27 kg, were divided into three groups. After laparotomy, the volume of the primary rectum was measured so that it could be compared with that of the neorectum at the end of the study. After rectal resection in Group A, the colon was directly anastomosed to the anus. In Group B, a 5-cm longitudinal incision was made 2 cm proximal to the anastomosis and was sutured transversely (coloplasty). In Group C, a 5-cm ileal J-pouch was interposed between the colon and anus. After 8 weeks, the neorectum was evaluated for volume, radiology, and pathology.Results: All the samples were alive until the end of the study. The healing of the anastomotic lines was acceptable (pathologically) in all. The mean volume expansion was 20.9% in Group A, 21.7% in Group B, and 118.2% in Group C, with the latter being significantly higher than that of the other groups (P=0.03). Colon J-pouch and coloplasty after proctectomy in some situations have not been performable. This study evaluated the performance of ileal J-pouch interposition. Conclusion: This study showed that ileal J-pouch interposition might produce an acceptable reservoir function and that it seems feasible and safe in selected cases.
- انتشار مقاله: 10-12-1392
- نویسندگان: Leila Ghahramani,Saeed Yazdani,Saeed Derakhshani,Abbas Rezaianzadeh,Reza Jalli,Bita Geramizadeh,Ali Reza Safarpour,Salar Rahimikazerooni,Seyed Vahid Hosseini
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Community Based Nursing and Midwifery
- نوع مقاله: Journal Article
- کلمات کلیدی: Iran,Quality of Life,Qualitative study,Morbid obesity
- چکیده:
- چکیده انگلیسی: Background: Morbid obesity (body mass index≥40 kg/m2 or >35 kg/m2 with co-morbidity) is an important factor in reducing the quality of life which is influenced by the characteristics of the individual, his social, cultural, and environmental conditions; also, each disease has unique effects on it. Although most of the studies have been conducted on obesity (25>BMI>40), how to prevent it and improve life quality, there is lack of knowledge about what morbid obese people really experience about their life quality. Thus, this qualitative study aimed to explore the viewpoints of morbid obese people about life quality.Methods: In this conventional content analysis, data were collected using semi-structured interviews with 20 morbid obese patients who were referred to nutrition and obesity clinics of Shiraz and Ahvaz Jundishapur University of Medical Sciences. Purposeful sampling was processed from May 2016 to January 2017. The sampling continued until data saturation. Each interview was recorded by audio recorder and typed in the MAXQDA10 software. Data were analyzed after each interview. The meaning units were encoded and the codes were categorized. This trend continued until the main and sub-categories emerged. Results: Data analysis indicated 1835 codes, 76 sub-subcategories, 26 subcategories and 6 main categories including physical changes, psychological experiences, socio-personal dysfunction, negative body image, financial pressure, and change in the spirituality.Conclusion: Final results indicated that life quality had a special definition in morbid obesity and includes very different dimensions. This study can promote health care providers’ knowledge (nurses) for supporting obese people and improving their quality of life by community-based care approaches.
- انتشار مقاله: 02-09-1397
- نویسندگان: Negar Yazdani,Farkhondeh Sharif,Nasrin Elahi,Seyed Vahid Hosseini,Abbas Ebadi
- مشاهده