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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Women’s Health Bulletin
- نوع مقاله: Journal Article
- کلمات کلیدی: Pregnancy,Luteinizing hormone,Chorionic Gonadotropin,Insemination,Clomiphene Citrate,Artificial
- چکیده:
- چکیده انگلیسی: Background: Infertility is becoming a world-wide concern in developed and developing countries. Multiple causes are responsible for the situations and various therapies have been developed to overcome this problem in infertile couples, as in the case of intrauterine insemination (IUI), with considerable variations between pregnancy rates in relation to the method employed. Objectives: To compare pregnancy rate, by human chorionic gonadotropin (HCG) administration and urinary luteinizing hormone (LH) surge method, for insemination in patients undergoing IUI. Patients and Methods: The present study included 309 infertile women, candidate for IUI, randomly divided into LH surge and HCG groups (each participant was assigned a number from 1 to 309, of which odd numbers were for LH and even numbers for HCG groups, respectively). All patients were subjected to baseline ultrasound and received clomiphene citrate before undergoing serial transvaginal sonography. The LH was measured using LH kit, when 2 - 5 follicles (18 - 20 mm) appeared in LH surge group, and, if positive, IUI was performed after 24 hours. In HCG group, the patients received HCG 1000 units and underwent IUI after 36 hours. The pregnancy rate was then compared in LH and HCG groups. Results: We found no significant differences in pregnancy rates between the two groups. Also, we compared pregnancy rates between the two groups based on age, infertility cause, number of follicles, number of previous IUI and previous abortions. We found no significant differences between the subgroups, in terms of pregnancy rate. Conclusions: The urinary LH surge and HCG administration methods for IUI timing are similar and none had any considerable advantages over the other. However, the use of the urinary LH surge has no side effects or injection pain, in relation to HCG administration methods
- انتشار مقاله: 11-10-1348
- نویسندگان: Seyedeh Houra Vahedolain,Seyedeh Azam Pourhosaini,Nayere Khadem,Seyed Mostafa Pashang,Ali Akbary,Seyed Taghi Heydari
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Otorhinolaryngology
- نوع مقاله: Journal Article
- کلمات کلیدی: Adenoidectomy,Adenoids,Tonsillectomy,Palatine tonsil,Insulin-Like Growth Factor I,Insulin-Like Growth Factor-Binding Protein 3
- چکیده:
- چکیده انگلیسی: Introduction:
Adenotonsillar hypertrophy (ATH) may present with growth retardation. Insulin-like growth factor 1 (IGF-1) mediates the anabolic effects of growth hormone (GH) on tissues. Most of the circulating IGF-1 molecules are bound to insulin-like growth factor-binding protein 3 (IGFBP-3). IGF-1 and IGFBP-3 serum levels reflect the levels of daily mean serum GH and are used as indices for evaluating the serum level of GH. This study aimed to determine the effect of adenotonsillectomy on IGF-1 and IGFBP-3 serum levels in patients with ATH or recurrent tonsillitis. Furthermore, we aimed to investigate the effect of adenotonsillectomy on growth indices such as weight and height.
Materials and Methods:
A total of 100 randomly selected children with a diagnosis of ATH or recurrent tonsillitis with a mean age of 10.2 ± 1.4 years (range, 3-17 years) were enrolled in the intervention group. Of those, 53 were boys and 47 were girls. The control group included 100 healthy children (62 boys and 38 girls) with a mean age of 8.5 ± 1.5 years (range, 4-15 years). Growth indices such as weight and height were measured and documented at the time of surgery and 6 months after the operation. Blood samples were taken preoperatively and repeated 6 months after adenotonsillectomy. The coated-tube immunoradiometric (IRMA) method was used to measure IGF-1 and IGFBP-3 levels.
Results:
Postoperative IGF-1 and IGFBP-3 serum levels as well as weight and height showed were significantly greater in comparison with preoperative measurements in both the intervention and control groups (P<0.001). At the end of study, the intervention group showed significantly greater changes from baseline in IGF-1 and IGFBP-3 serum levels, weight, and height in comparison with the control group (P< 0.001).
Conclusions:
This study shows that adenotonsillectomy in children with ATH or recurrent tonsillitis increases IGF-1 and IGFBP-3 serum levels in comparison with preoperative levels by affecting the GH-IGF-1 axis, and subsequently leads to a faster increase in growth indices compared with healthy peers during the same period.- انتشار مقاله: 06-10-1394
- نویسندگان: Mohammad Faramarzi,Mahmood Shishegar,Seyed Taghi Heydari,Arash Haghighi,Hadi Sharouny
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Medical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: Iran,Meta-Analysis,Vitamin D deficiency
- چکیده:
- چکیده انگلیسی: Background: The prevention and correction of vitamin D deficiency requires a precise depiction of the current situation and identification of risk factors in each region. The present study attempted to determine these entities using a systematic review and meta-analysis in Iran.Methods: Articles published online in Persian and English between 2000 and November 1, 2016, were reviewed. This was carried out using national databases such as SID, IranMedex, Magiran, and IranDoc and international databases such as PubMed, Google Scholar, and Scopus. The heterogeneity index among the studies was determined using the Cochran (Q) and I2 test. Based on the heterogeneity results, the random-effect model was applied to estimate the prevalence of vitamin D deficiency. In addition, meta-regression analysis was used to determine heterogeneity-suspected factors, and the Egger test was applied to identify publication bias.Results: The meta-analysis of 48 studies identified 18531 individuals with vitamin D deficiency. According to the random-effect model, the prevalence of vitamin D deficiency among male, female, and pregnant women was estimated to be 45.64% (95% CI: 29.63 to 61.65), 61.90% (95% CI: 48.85 to 74.96), and 60.45% (95% CI: 23.73 to 97.16), respectively. The results of the meta-regression analysis indicated that the prevalence of vitamin D deficiency was significantly different in various geographical regions (β=4.4; P=0.023).Conclusion: The results obtained showed a significant prevalence of vitamin D deficiency among the Iranian population, a condition to be addressed by appropriate planning.
- انتشار مقاله: 03-05-1395
- نویسندگان: Reza Tabrizi,Mahmood Moosazadeh,Maryam Akbari,Mohammad Hossein Dabbaghmanesh,Minoo Mohamadkhani,Zatollah Asemi,Seyed Taghi Heydari,Mojtaba Akbari,Kamran B Lankarani
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Medical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: mortality,Stroke,sex,Cerebrovascular disease,Cerebrovascular accident
- چکیده:
- چکیده انگلیسی: Background: Unlike the western hemisphere, information about stroke epidemiology in southern Iran is scarce. The aim of this study was to determine the main epidemiological characteristics of patients with stroke and its mortality rate in southern Iran.Methods: A retrospective, single-center, hospital-based longitudinal study was performed at Nemazee Hospital in Shiraz, Southern Iran. Patients with a diagnosis of hemorrhagic and ischemic strokes were identified based on the International Classification of Diseases, 9th and 10th editions, for the period between 2001 and 2010. Demographics including age, sex, area of residence, socioeconomic status, length of hospital stay, and discharge destinations were analyzed in association with mortality. Results: 16351 patients with a mean age of 63.4 years (95% CI: 63.1, 63.6) were included in this analysis. Men were slightly predominant (53.6% vs. 46.4%). Forty-seven percent of the total sample was older than 65,17% were younger than 45, and 2.6% were children younger than 18. The mean hospital stay was 6.3 days (95% CI: 6.2, 6.4). Among all types of strokes, the overall hospital mortality was 20.5%. Multiple logistic regression revealed significantly higher in-hospital mortality in women and children (P<0.001) but not in patients with low socioeconomic status or from rural areas. During the study period, the mortality proportions increased from 17.8% to 22.2%. Conclusion: In comparison to western countries, a larger proportion of our patients were young adults and the mortality rate was higher.
- انتشار مقاله: 06-07-1392
- نویسندگان: Afshin Borhani-Haghighi,Rasool Safari,Seyed Taghi Heydari,Faroq Soleimani,Maryam Sharifian,Sara Yektaparast Kashkuli,Mahsa Nayebi Khayatghuchani,Mahbube Azadi,Abdolhamid Shariat,Anahid Safari,Kamran Bagheri Lankarani,Amer Alshekhlee,Salvador Cruz-Flores
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Community Based Nursing and Midwifery
- نوع مقاله: Journal Article
- کلمات کلیدی: Health care,Mother-child relation,Disabled persons,Attachment theory
- چکیده:
- چکیده انگلیسی: Background: Families with disabled children need more psycho-social considerations. Motherhood care of the children with multiple disabilities is difficult. Due to its importance, the aim of this study was to investigate the causal factors affecting loving care of mothers of children with multiple disabilities.Methods: The study used a cross-sectional method in which 75 mothers of exceptional children with multiple disabilities (physical and mental) in elementary schools in Shiraz, Iran. The data were collected through questionnaires which, besides demographical factors, evaluated the relationship between mothers’ loving care of children with multiple disabilities and four other variables including purpose in life, life satisfaction, religious attitude, and sense of coherence. Mann-Whitney U was used for comparison between mothers’ loving care and other variables.Results: Results revealed that demographic variables did not have a significant relationship with loving care. In the case of social variables, there was a significant relationship between mothers’ loving care and purpose in life (P<0.001), religious attitude (P<0.001), and life satisfaction (P=0.01).Conclusion: Motherhood care of disabled children is a unique phenomenon which is due to attachment of mother-child situation. Nevertheless, these mothers are vulnerable and marginalized people who need more attention and social supports provided by related governmental institutions and also NGOs actors.
- انتشار مقاله: 15-11-1393
- نویسندگان: Ahmad Kalateh Sadati,Hamze Salehzade,Soroor Hemmati,Manijeh Darvish,Seyed Taghi Heydari,Reza Tabrizi
- مشاهده
- جایگاه : پژوهشی
- مجله: Bulletin of Emergency and Trauma
- نوع مقاله: Journal Article
- کلمات کلیدی: Iran,Attention-Deficit/Hyperactivity Disorder,Driving behavior,Motorcycle
- چکیده:
- چکیده انگلیسی: Objective: To investigate the association between attention-deficit/hyperactivity disorder (ADHD) score and driving behaviors among motorcycle drivers in Iran.
Methods: This multi-center cross-sectional study was conducted on 1747 motorcyclists in three cities of Iran. We used a random sampling method in this study and gathered data using two standard questionnaires. Data were presented using descriptive statistics, also t-test, and ANOVA used for analysis.
Results: The mean age of participants was 27.41±8.80 years. ADHD scores of the participants ranged from 0 to 87, with a mean score 31±15.86. All risky driving behaviors (RDBs) were significantly associated with a higher mean of ADHD score. For example, driving with illegal speed (p<0.001), not wearing a crash helmet (p=0.016), driving while exhausting (p<0.001), talking with other passengers (p<0.001), being fined by the police in the past year (p=0.028), and maneuvering while driving (p<0.001) were related to a higher mean of ADHD score.
Conclusion: All RDBs were significantly associated with the ADHD score among motorcyclists in Iran. In this regard, health care providers should inform people with ADHD about the negative consequences associated with driving and ADHD. Public health policymakers should consider management of ADHD through a comprehensive approach to improve driving performance and competencies among motorcyclists in order to decrease RDBs and traffic accidents.- انتشار مقاله: 24-10-1398
- نویسندگان: Ali Akbary,Seyed Taghi Heydari,Yaser Sarikhani,Mehrdad Vossoughi,Reza Tabrizi,Maryam Akbari,Najmeh Movahhedian,Arash Mani,Homayoun Sadeghi-Bazargani,Tahereh Ostovar,Kamran Bagheri Lankarani
- مشاهده
- جایگاه : پژوهشی
- مجله: Canon Journal of Medicine
- نوع مقاله: Journal Article
- کلمات کلیدی: Quality of Life,Free Tissue Flaps,Surgical Flaps,head and neck neoplasms
- چکیده:
- چکیده انگلیسی: Introduction: Reconstruction surgeryfor head and neck cancers restore patients’ function and appearance. Careful selection of flap for reconstruction of a defect after an ablative surgery can be a complex process and may affect on quality of life (QOL) of the patients. This study aimed to compare the quality of life between free and pedicle flap reconstruction groups in head and neck neoplasm patients.
Methods: This was a cross-sectional study of QOL in patients withhead and neck neoplasm that attend follow-up clinics from July to September 2019. All patients that underwent reconstructive surgery with either pedicle or free flaps were included in the study. At least 6 month-time was elapsed from the reconstructive surgery. QOL of the patients was evaluated using Medical Outcomes Study Short Form (MOS SF-36) questionnaire. The patients’ demographic data and medical history were collected using electronic patients’ records.
Results: Seventy patients completed the questionnaire. Forty one (58.57%) patients underwent pedicle and 29 (41.43%) patients free flap reconstructive surgery. There was no significant difference between pedicle and free flap groups with regard to age, gender, radiotherapy or chemotherapy (P>0.05).
The present study indicates that there was no statistically significant difference between pedicle and free flap groups with regard to 8 domains of SF-36 questionnaire (P>0.05), neither was significant difference between two groups with regard to the physical or mental component summaries (P>0.05).
Conclusion: The present study on quality of life of head and neck neoplasm patients that had undergone pedicle or free flaps showed no significant difference between two groups.- انتشار مقاله: 14-06-1398
- نویسندگان: Mehrdad Jafari,Maziar Motiee Langrudi,Seyed Taghi Heydari,Ebrahim Karimi,Hadi Sharouny
- مشاهده
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: Breast cancer,Support,Perceived Priority
- چکیده:
- چکیده انگلیسی: Objective: Cancer is a stressful event in life, and the dreadful impact and problems created for patients and families
by cancer negatively affect their quality of life. Therefore, regarding the increasing number of cancer patients and the
nature of this disease, the need to recognize and understand the priorities and problems of patients after the diagnosis of
cancer is of high importance. This study was designed and implemented with the aim of identifying the perceived
priorities of women with breast cancer. Methods: This study is a qualitative research of content analysis type. To collect
data, purposeful sampling and deep semi-structured individual interviews were used. The subjects were women with
breast cancer who visited the Breast Disease Research Center of Shahid Motahari Clinic in Shiraz, and the data were
saturated after 15 interviews. The four criteria presented by Lincken and Guba were used to evaluate the validity and
reliability. To analyze the qualitative data, conventional qualitative data analysis and MAXQDA10 software were used.
Two themes were obtained in the assessment of interviews and analysis of data: 1) Supportive relief; 2) Therapeutic
support. Results: Some of the participants highlighted the role of social and family support in coping with the disease,
and considered social communication and continued support in the form of empathic relationship as a turning point
in their lives. The absence of a fertility specialist in the cancer treatment system was the main complaint of most
participants. The results showed that receiving support from family and the healthcare system is the most important
perceived priorities in breast cancer patients. Conclusion: The results of this study show the importance of social support
as a perceived priority in breast cancer patients to improve their quality of life. Development and reinforcement of the
supportive network seem to be essential to provide the best possible help to these patients.- انتشار مقاله: 27-05-1397
- نویسندگان: Seyede Zahra Ghaemi,Zohreh Keshavarz,Sedigheh Tahmasebi,Majid Akrami,Seyed Taghi Heydari
- مشاهده