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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Annals of Colorectal Research
- نوع مقاله: Journal Article
- کلمات کلیدی: essential oil,Zataria multiflora,Hematological parameters,Biochemical parameters,Clinical study
- چکیده:
- چکیده انگلیسی: Abstract
Background: Zataria multiflora Boiss is a well-known medicinal plant and its’ essential oil (EO) is traditionally used for treatment of respiratory and digestive disorders and/or bacterial, viral, fungal, and parasitic infections.
Objective: This study was undertaken to evaluate the effect of long-term consumption of Z. multiflora EO on hematological and biochemical parameters in patients infected with liver hydatid disease.
Materials and Methods: Fifteen patients were administered orally with Z. multiflora EO (60 mg daily) for six months. Hematological and biochemical analysis were performed on the blood samples of patients before the start of treatment and after completion of the treatment course. In hematological analysis, WBC, RBC, Hb, hematocrit, MCV, MCH, MCHC and platelets were measured. In biochemical analysis, FBS, BUN, creatinine, cholesterol, triglycerides, HDL, LDL, Na, K, Cl, AST, ALT, and ALK were assessed.
Results: No apparent changes were observed in the values of hematological parameters of the patients after treatment. No significant changes also occurred in the values of FBS, BUN, creatinine, cholesterol, triglycerides, HDL, LDL, Na, and K. The mean values of AST, ALT and ALK enzymes decreased significantly after treatment (P ˂ 0.05). No adverse clinical event was noticed in the patients during the course of study.
Conclusions: Long-term consumption of Z. multiflora EO induced no adverse effect on the hematological and biochemical parameters of patients infected with liver hydatid disease. Since Z. multiflora EO reduced the level of liver transaminases (AST, ALT and ALK), this herbal product may be considered as a hepatoprotective agent in human beings.- انتشار مقاله: 07-11-1398
- نویسندگان: Arash Jafari,Mohammad Moazeni,Seyed Vahid Hosseini,Hajar Khazraei,Samane Nematolahi,Seyed Mohammad Kazem Tadayon
- مشاهده
- جایگاه : پژوهشی
- مجله: Annals of Colorectal Research
- نوع مقاله: Journal Article
- کلمات کلیدی: Anal sphincter,Healing,Platelet-Rich plasma,sphincterotomy,Sphincteroplasty
- چکیده:
- چکیده انگلیسی: Background: Inability to manage of stool release, fecal incontinence, is a condition with sever negative effects on the patients’ quality of life. Use of platelet-rich plasma in healing of anal sphincter might improve outcomes. The current study investigated the healing effects of PRP application after surgical repair of sphincter in rabbits as an animal model for human studies.
Methods: Twenty-four New Zealand rabbits were randomly allocated into 4 groups based on the time of healing at one and three weeks after sphincteroplasty and using of PRP. Sphincterotomy and then sphincteroplasty were performed in all animals and autologous PRP was prepared and used as dose as 0.5 ml per animal. The healing scores of sphincter were compared between four groups using histological scoring system.
Results: The histological healing score in PRP used group was significantly higher than not PRP used group after one week (18.6 ± 0.8 vs. 13.0 ± 1.8 respectively, P = 0.01) but no significant difference was detected between healing score of PRP used and not PRP used groups after three weeks (19.0 ± 0.0 vs. 18.5 ± 0.8 respectively, P = 0.17).
Conclusion: Our findings indicated that although PRP had an accelerator role in wound healing of sphincter repair, but it has not significant effects over time especially after 3 weeks.- انتشار مقاله: 20-08-1398
- نویسندگان: Ahmad Izadpanah,Habibollah Nikzad Jamnani,Alireza Safarpour,Ahad Izadpanah,Seyed Mohammad Kazem Tadayon
- مشاهده