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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Reviews in Clinical Medicine
- نوع مقاله: Journal Article
- کلمات کلیدی: Child,Gastroenteritis,Convulsion
- چکیده:
- چکیده انگلیسی: Convulsion with mild gastroenteritis is an afebrile seizure associated with viral gastroenteritis in a healthy child without fever, dehydration, electrolyte imbalance, meningitis, or encephalitis. Convulsion with mild gastroenteritis is more common in children aged 1 to 2 years. Usually, Convulsions are brief generalized tonic colonic type. Most convulsions occur within first 24 hours of illness onset. Rotaviral gastroenteritis is known as the most common type of gastroenteritis associated with Convulsion. Laboratory investigations are normal. Also EEG and neuroimaging are usually normal. Long term antiepileptic treatment is not necessary. It is usually a benign condition with good prognosis and no risk for developing epilepsy in future. Considering this etiology of seizure could prevent supernumerary evaluations and long-term antiepileptic treatment.
- انتشار مقاله: 17-06-1395
- نویسندگان: Maryam Khalesi,Farhad Heydarian,Seyed Javad Sayedi,Shima Badzai,Elahe Heidari
- مشاهده
- جایگاه : پژوهشی
- مجله: Reviews in Clinical Medicine
- نوع مقاله: Journal Article
- کلمات کلیدی: Child,Gastroenteritis,Convulsion
- چکیده:
- چکیده انگلیسی: Convulsion with mild gastroenteritis is an afebrile seizure associated with viral gastroenteritis in a healthy child without fever, dehydration, electrolyte imbalance, meningitis, or encephalitis. Convulsion with mild gastroenteritis is more common in children aged 1 to 2 years. Usually, Convulsions are brief generalized tonic colonic type. Most convulsions occur within first 24 hours of illness onset. Rotaviral gastroenteritis is known as the most common type of gastroenteritis associated with Convulsion. Laboratory investigations are normal. Also EEG and neuroimaging are usually normal. Long term antiepileptic treatment is not necessary. It is usually a benign condition with good prognosis and no risk for developing epilepsy in future. Considering this etiology of seizure could prevent supernumerary evaluations and long-term antiepileptic treatment.
- انتشار مقاله: 17-06-1395
- نویسندگان: Maryam Khalesi,Farhad Heydarian,Seyed Javad Sayedi,Shima Badzai,Elahe Heidari
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Otorhinolaryngology
- نوع مقاله: Journal Article
- کلمات کلیدی: Surgery,Anesthesia,Congenital abnormality
- چکیده:
- چکیده انگلیسی: Introduction:
Intraoral synechia is a rare congenital condition, generally associated with other maxillo-facial malformations. We present a neonate with congenital intraoral bilateral synechia without any other facial anomalies.
Case Report:
In this paper, we present a 19-day-old male neonate with congenital intraoral bilateral synechia without any other facial anomalies. We review the literature to discuss the surgical andanesthesia management of this rare congenital disease.
Conclusion:
The disease manifested with a wide spectrum of symptoms. Most cases need surgery and airway management. In patients with a low risk of bleeding or a compromised airway, it is possible to manage them withfacemask-inhalation anesthesia and maintain spontaneous breathing.- انتشار مقاله: 26-08-1396
- نویسندگان: Mohammad Gharavifard,Iman Kashani,Marjan Joodi,Majid Sharifian,Seyed Javad Sayedi,Behrouz Mohammadipanah,Farideh Jamali- Behnam
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: Pregnancy,COVID-19,neonate
- چکیده:
- چکیده انگلیسی: Background
The COVID-19 infection, which has been a pandemic since early 2020, can occur in pregnant women and can be transmitted to the baby after birth. There are few reports of this transmission in newborns. Because there are several causes for respiratory symptoms in a neonate, it is difficult to diagnose COVID-19 infection in the newborn. Evaluation of antibody in the blood umbilical cord may be an option in the future. We studied the COVID-19 infection in newborns.
Materials and Methods
In this longitudinal follow-up study, pregnant mothers who had suspicious symptomsof coronavirus infection before or after childbirth were consulted by the medical team for neonatal infection. Newborns were evaluated for respiratory symptoms. PCR test for corona virus was performed on pharyngeal swab or tracheal tube sample of the newborns.
Results
Twenty-five pregnant women with symptoms suspicious coronavirus infections were consulted by the team of specialists from March 15 to April 15, 2020. After delivery their babies were carefully examined and followed up. Four neonates had coronavirus confirmed by PCR test.
Conclusion
Our study showed that neonates can become infected with Covid-19 and it should be considered amongst various differential diagnosis of neonatal respiratory diseases.- انتشار مقاله: 30-01-1399
- نویسندگان: Ahmad Shah Farhat,Seyed Javad Sayedi,Farideh Akhlaghi,Abdolkarim Hamedi,Alireza Ghodsi
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: children,Iran,Symptoms,Cystic fibrosis,Growth pattern
- چکیده:
- چکیده انگلیسی: Background
Cystic fibrosis (CF) is the most prevalent lethal chronic genetic and multivariate disease, widespread in Iranian population. The aim of this study was to evaluate the condition of patients with CF from various dimensions in the last decades in Iran.
Materials and Methods
In this cross-sectional study the data were collected from disease registrydatabase of CF patients in Pediatric Respiratory Disease Research Center in Masih Daneshvari, Tehran, Iran. The patients were divided into female and male.The data were collected based on province, birthplace province, marital status, and degree of education, parental consanguinity ratio, age, and age of onset of symptoms, age of onset of diagnosis and body mass index (BMI).
Results
Majority of patients (n=169, 59.3%) were male, born in Tehran province (n=81, 28.4%), and live in Tehran province (n=102, 35.8%). Majority of parents (61.1%, n=174) had consanguineous relation and the rest (n=94, 33%) did not have any consanguineous relation. Results show that mean of age, age of diagnosis, mean for expression of first symptoms and mean of time interval between the onset of symptoms and the diagnosis of the disease were 14.52, 2.51, 6.57, and 4.07 years, respectively. Results showed that high percentage of patients (n=191, 67%) had lower BMI (<18.50), and low percentage (n=3, 1.1%) showed higher BMI (>25). Correlation coefficient also showed positive relation between start age of symptoms and diagnosis age of disease.
Conclusion
In Iran, CF is a multisystem disease and age for its expression is different. Since mean for time interval between the onset of symptoms and the diagnosis of the disease- انتشار مقاله: 22-02-1398
- نویسندگان: Maryam Hassanzad,Masoumeh Ansari,Ali Valinejadi,Seyed Javad Sayedi,Ali Akbar Velayati
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: Vitamin D,Cystic fibrosis,Low Bone Mineral Density,Genetic Factors
- چکیده:
- چکیده انگلیسی: Cystic fibrosis (CF) is a common progressive genetic disorder among children which involves lungs, kidneys, intestine and liver. Apart from the significance of genetic factors, various environmental factors particularly bone mineral density are directly associated with CF. Remarkably, bone disease is appeared as a routine and common trait in long term CF survivors which implies that environmental parameters including calcium and vitamin D intake as well as drug inducement are the most important risk factors causing low bone mineral density. Conspicuously, absolute and notable treatment of cystic fibrosis associated to bone disorder must involve investigating the risk factors including the reduced intake of certain vitamins and minerals due to pancreatic inadequacy, modified hormone production, severe and chronic lung infection with increased ranges of bone function cytokines for a weak bone health situation. In this review, focus is on these considerable factors alongside the genetic factors in cystic fibrosis.
- انتشار مقاله: 21-12-1397
- نویسندگان: Maryam Hassanzad,Poopak Farnia,Ali Akbar Samadani,Seyed Javad Sayedi,Ali Akbar Velayati
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: children,Bronchoscopy,Cough,Foreign body aspiration
- چکیده:
- چکیده انگلیسی: Foreign body aspiration is a potentially life-threatening event especially in those who are younger than 5 years old. Aspiration could be presented as a spectrum, ranging from absolutely asymptomatic event to more sever events including choking, respiratory distress and cyanosis or even death. Although foreign bodies in lung may not be visualized on X-ray, X-ray radiography is considered as a first step in localizing aspirated foreign bodies. Bronchoscope as rigid or flexible optic fiber is the main device used in removing aspirated foreign bodies.
However, in some cases, as the present case report, previous foreign bodies which were localized in lung could travel back to the mouth and be ingested. In this report, we discussed a case of foreign body aspiration in a 10 year-old girl referred to Dr. Sheikh Hospital, Mashhad, Iran, whose foreign body located in the lower lobe of the left lung returned and was ingested before bronchoscopy after some episodes of sever coughing.- انتشار مقاله: 22-08-1397
- نویسندگان: Seyed Javad Sayedi,Mohammad Gharavi Fard,Ali Khakshour,Mahboubeh Davoudi Kang,Iman Kashani,Reza Jafarzadeh Esfehani
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: children,Prevalence,mutations,Cystic fibrosis,sweat test
- چکیده:
- چکیده انگلیسی: Background: Cystic fibrosis (CF) is the most common lethal genetic disorder of Cystic Fibrosis Trans-membrane Conductance (CFTR) Regulator gene mutations. We aimed to investigate common mutations in CF patients and to assess its possible relationship with clinical presentations.
Materials and Methods: This cross sectional study was conducted on 36 CF patients who were referred to a tertiary pediatric hospital in Isfahan, Iran. They were evaluated for 34 common mutations in CFTR gene by using reverse dot blot strip assay. Other parameters such as the age of diagnosis, the sweat chloride level, and clinical manifestations due to lung involvement and pancreatic insufficiency were also assessed. According to genotype mutations, children were divided in three groups: ΔF508 mutation (group 1), non-ΔF508 mutation (group 2), without current mutations (group 3). Finally, genotype, and phenotype relationship were reported.
Results: The mean age of patients was 8.1+2.3 months, and 23 of them (63%) were male. CFTR mutations were found in fourteen patients (38.8%). ΔF508 mutation has the highest prevalence in the studied samples with allele frequency of 15.27%, and c. 2183 AA>G was in the second standing. Furthermore, p.R553X, p.G542X, C.1766+1, p.N1303K mutated alleles also were obtained in lower level. Mean age at the diagnosis time of CF, sweat chloride level and pancreatic insufficiency were not different between groups but lung complications were significant in children with common mutations.
Conclusion: Our findings showed that commercial kit designed to identify 34 common CFTR mutations failed to detect 61.2% of alleles of our patients. This necessitates designing local diagnostic kits for proper diagnosis of CF in Iranian children.- انتشار مقاله: 27-08-1397
- نویسندگان: Mohsen Reisi,Mahdiyeh Behnam,Seyed Javad Sayedi,Farzaneh Salimi,Pegah Kargar,Mansoor Salehi,Hossein Saneian,Iman Kashani,Roya Kelishadi
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: Coenzyme Q10,Anthropometry,Cystic fibrosis,Respiratory System
- چکیده:
- چکیده انگلیسی: Background: Cystic Fibrosis (CF) is a hereditary autosomal recessive genetic disorder that can affect many organs including the lungs and the digestive system. We aimed to assess the effects of coenzyme Q10 level on clinical parameters in cystic fibrosis patients.
Materials and Methods
This cross-sectional study was performed on 40 patients (13 females and 19 males) with cystic fibrosis who were admitted in Masih Daneshvari Hospital in Tehran- Iran, in 2017. A researcher-made questionnaire was distributed among them, and then the height, weight and arm circumference of the patients were measured and also their serum Q10 levels were evaluated. Then, the pulmonary function was evaluated using a 6-minute respiration test and a spirometry test. Finally, their total scores were calculated based on Shwachman score.
Results: The age range of participants was from 6 to 27 years old. Anthropometric indices such as weight (p=0.02, r=-0.408), age (p=0.016, r=-0.422), height (p=0.002, r=-0.520), birth weight (p=0.0113, R=-0.286), and height at birth (p=0.037, r=-0.37) had a significant negative relationship with coenzyme Q10. There was relationship between anthropometric indices and spirometry tests, including the association of FEV1 (act) with weight (p=0.00), and arm circumference (p=0.00) which were determined.
Conclusion: According to the results, there was no direct relationship between muscle mass and Q10. Besides, the mean age of Q10 was greater than that of in age group of 9-16 years old, which can be considered for nutrition or childhood reserves for coenzyme Q10 production, which is decreased due to increasing age and lack of intake or loss of body power for the production of coenzyme Q10.- انتشار مقاله: 15-08-1397
- نویسندگان: Hassan Mozaffari Khosravi,Mohammad Ali Hojjati Kermani,Maryam Hassanzad,Mansour Rezaie,Sabereh Tashayoie-Nejad,Seyed Javad Sayedi,Ali Akbar Velayati
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: children,lead,Blood,Failure to Thrive
- چکیده:
- چکیده انگلیسی: Background
Lead is a strong and stable toxin, harmful especially to children, pregnant women, and the elderly. Nearly 27% of children aged under 5 years suffer from failure to thrive (FTT). Due to the probable harmful effects of lead poisoning on children’s growth, in this study we aimed to assess the blood lead level in children with unexplained failure to thrive.
Methods
This analytic cross-sectional study was performed on 200 children under 2 years of age who were referred to Ghaem hospital, a referral hospital in Mashhad city-Iran. The participants were divided into two equal groups, one with unexplained FTT (group A), and children with normal weight (group B). Baseline characteristics were obtained by a research-made questionnaire. Blood samples were taken by the hospital nurses who were blind to the study groups. Blood lead level was measured by atomic absorption spectrophotometric method (Perkin Elmer 3030).
Results
The mean ± standard deviation (SD) of blood lead level in FTT group and control group were 7.3±3.32 µg/dL and 6.37±5.93 µg/dL, respectively. Blood lead level was significantly higher in FTT group than control group (P=0.001). Baseline Charactistics (such as hgender, parental educational level, gestational age, and socio-economic status of the family) were not significantly different between the two groups (P>0.05).
Conclusion
The results of our study revealed that blood lead level was higher in children with FTT. So Lead poisoning may be a potential cause of unexplained FTT. So, measuring blood lead level can be useful in diagnostic workup of patients with FTT.- انتشار مقاله: 16-09-1397
- نویسندگان: Simin Torabian,Mohammad Ali Kiani,Alizadeh Ghamsari Anahita,Seyed Ali Jafari,Masumeh Saeidi,Ali Khakshour,Seyed Javad Sayedi,Hamidreza Kianifar
- مشاهده