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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: Overall Survival,Risk Factor,Recurrence-free survival,Endometrial cancer,adenomyosis
- چکیده:
- چکیده انگلیسی: Objective: To determine the effects of uterine adenomyosis on endometrial cancerrecurrence rates. Methods: This
retrospective cohort study reviewed all consecutive patients diagnosed with endometrial cancerwho underwent total
hysterectomy-based surgical staging at Srinagarind Hospital between January, 2010 and January, 2016. The patientswere
divided into two groups:a uterine adenomyosisgroup and a non-adenomyosis group. Patient demographics, type of
surgery, histopathology, stage of endometrial cancer, adjuvant treatment, and survival outcomes were compared.
Results: A total 350 patients were enrolled, with 132 (37.71%) in the adenomyosis group and 218 (62.29%) in the nonadenomyosis group. Deep myometrial invasion and lymphovascular space invasion (LVSI) were more commonly found
among patients who had no adenomyosis compared to those with adenomyosis(52.8% vs 39.4%, P=0.02 and 53.2%
vs. 38.6%, P=0.01). There were no significant differences in terms of five-year recurrence-free survival (HR=1.47;
95%CI 0.88-2.44) and five-year overall survival (HR=0.81; 95%CI 0.43-1.53) between the two comparison groups.
Conclusion: Coexisting uterine adenomyosis in endometrial cancer wasassociated withdeep myometrial invasion and
LVSI but did not have significant impact on survival.- انتشار مقاله: 18-07-1397
- نویسندگان: Sarana Boonlak,Apiwat Aue-Aungkul,Chumnan Kietpeerakool,Pilaiwan Kleebkaow,Bandit Chumworathayi,Sanguanchoke Luanratanakorn,Amornrat Temtanakitpaisan
- مشاهده