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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: children,Pneumonia,Cyanosis-Tachypnea,Zinc sulfate
- چکیده:
- چکیده انگلیسی:
Background: Acute respiratory infections and especially pneumonia are considered as the most important infection-induced cause of child mortality in developing countries. We aimed to investigate the effect of prescribing zinc sulfate on improving the clinical symptoms of pneumonia in 2-59-month-old children.
Materials and Methods: This clinical trial study was performed on 108 children complaining of fever, coughs, and tachypnea referring to three educational hospitals of Mashhad (Ghaem, Imam Reza, and Dr. Sheikh). The patients were randomly assigned into control (n=54), and intervention (n=54). In the control group placebo was prescribed, while the intervention group received oral zinc sulfate 10 mg (1 ml/ kg in children younger than one year, and 20 mg/kg for children above one year every 12 hours. During hospitalization, every 12 hours the clinical symptoms of both groups including tachypnea, duration of fever, coughs, intercostal retraction, hypoxia, crackles-wheezing, and duration of hospitalization were recorded. At the beginning and end of the treatment, two blood samples were taken for determining the serum level of zinc.
Results: The findings indicated that the serum level of zinc sulfate after the intervention increased significantly in the intervention group (p <0.001). There was a significant difference in the duration of fever between the intervention and control groups 24 hours after hospitalization (p=0.014) and 36 hours post-hospitalization (p=0.02). Comparing the presence or absence of tachypnea in the intervention and control groups, there was a significant difference at 36 hours post-hospitalization (p=0.02).
Conclusion: Based on the results, zinc supplement was effective for patients with pneumonia in reducing the duration of fever and number of breaths, but it had no significant effect on the duration of coughs and hospitalization.- انتشار مقاله: 02-02-1399
- نویسندگان: Farhad Heydarian,Mona Nasiri,Ali Reza Attaei Nakhaie,Hamid Ahanchian,Somayeh Ghahremani,Ali Haghbin,Sarah Ghahremani
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: children,Clinical symptoms,Laboratory results,Systemic Lupus Erythematous
- چکیده:
- چکیده انگلیسی: Background: Systemic lupus erythematous (SLE) is a multisystemic and autoimmune inflammatory disease characterized by production of autoantibodies against different cellular components. We aimed to investigate children with SLE in terms of clinical symptoms and laboratory findings who referred to Lupus clinic.
Materials and Methods: In this cross-sectional study, 36 children with SLE referring to lupus clinic of Dr. Sheikh hospital, Mashhad-Iran, were enrolled for one year. Clinical symptoms and involvement of different organs were completely checked and recorded at the time of diagnosis of lupus disease based on questionnaire information. The patients with nephritic manifestations of lupus underwent needle biopsies of kidneys, with the samples being examined by light microscope and immunofluorescence to investigate the extent of renal involvement. The main course of treatment included steroid- cyclophosphamide (injection and oral), hydroxychloroquine - mycophenolate (Cellcept) and Azathioprine. Then, response or lack of treatment response as well as the extent and severity of relapse were recorded based on questionnaire.
Results: In this study, out of 36 lupus patients, 30 were female (83.3%). The mean age was 9.15±4.28 years. Lupus nephritis, musculoskeletal manifestations, hematological manifestations, cutaneous manifestations, and neurological manifestations existed in 20 (55.6%), 11 (30.6%), 9 (25.0%), 7 (19.4%), and 4 (11.1%), respectively. There was no significant relationship between the age plus gender and lupus clinical manifestations. However, there was a significant relationship between relapse of disease and lupus nephritis (p- انتشار مقاله: 25-04-1398
- نویسندگان: Zahra Chaichi,Mohammad Esmaeili,Abdolreza Malek,Fatemeh Ghane Sharbaf,Anoush Azarfar,Nafiseh Ghaffarian Eidgahi Moghaddam,Gholamreza Sarvari,Sarah Ghahremani
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: Factor analysis,Systematic review,Postpartum Bonding Questionnaire
- چکیده:
- چکیده انگلیسی: Background
Postpartum Bonding Questionnaire (PBQ) is a remarkable tool to assess impairments in the mother-infant bonding. The purpose of the present study was to review the factorial structure of the PBQ cross different versions.
Materials and Methods
The search strategy was implemented on databases of Medline (via PubMed), Scopus, Cochran library and Web of Science through electronic databases. The quality assessment was fulfilled by COSMIN checklist.
Results: The four factors were identified in original English version of PBQ. Theses consisted of "impaired bounding", "rejection and anger", "anxiety about care of the baby", and "risk of abuse". Three-factor-solution was confirmed by other English versions. In the Italian version of PBQ, three factors emerged including "annoyance and anger toward the infant", "detachment and rejection" and "anxiety about infant care". In the Spanish version of the PBQ, four factors including "impaired bonding", "anxiety about care", "lack of enjoyment and affection for the baby", and "rejection and risk of abuse". Three studies assessed factorial structure of Japanese version of PBQ. In the first Japanese version, four factors with 14 items were emerged including "impaired bonding ", "rejection and anger" and "anxiety about care", and "lack of affection". In second adapted Japanese version, exploratory factor analysis (EFA) identified a three factor solution: "mother's annoyance with anger toward their baby", "lack of affection" and" rejection and fear". The third version identified one-single solution. In the German version, one single factor emerged that explained 31 of the total variance.
Conclusion
Original English version of PBQ was not confirmed in Japanese, Italian, Spanish and other English versions.- انتشار مقاله: 24-08-1397
- نویسندگان: Sarah Ghahremani,Hossein Aryan,Somayeh Ghahremani,Forough Rakhshanizadeh,Rahele Rahimi,Masumeh Ghazanfarpour
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: children,corticosteroid,Coronary artery lesions,Kawasaki
- چکیده:
- چکیده انگلیسی: Background
Kawasaki Disease (KD) is a vasculitis with multi-organ involvementof unknown etiology; it is the most common cause of pediatric-heart diseases in developed countries. Treatment with Intravenous Immunoglobulin (IVIG) prevents coronary artery lesions; although there are some IVIG-resistant cases, combination therapy with corticosteroids and IVIG is one of the recommendations for treatment of these cases. The aim of this study was to compare these three options for treatment of Kawasaki Disease and to evaluate their ability to deal with coronary artery complication of Kawasaki Disease.
Materials and Methods
A prospective cross- sectional study of hospitalized cases of Kawasaki Disease, conducted in pediatric department of Imam Reza hospital, Mashhad-Iran, during 2013 to 2015 (18 months). Based on demographic and clinical data of these patients, children with high risk of unresponsiveness to IVIG therapy (based on Harada score), were determined and treated with IVIG and corticosteroids- combination initially. Follow-up patients for heart complications were 6 weeks.
Results
Twenty five patients (89.2%) out of total 28 hospitalized patients in this period of time who fulfilled diagnostic criteria were considered as complete Kawasaki Disease. Coronary Artery Lesions (CALs) were shown in 4 patients during the follow-up period, with high risk in patients with incomplete presentation (33.3% versus 12%, P<0.05). None of the children were treated with IVIG and corticosteroids combination therapy at the onset showed coronary artery lesions.
Conclusion
The current study showed that IVIG plus intravenous methylprednisolone (IVMP) combination therapy is a safe and effective treatment regimen in prevention of CALs.- انتشار مقاله: 08-04-1395
- نویسندگان: Abdolkarim Hamedi,Sarah Ghahremani,Abdolreza Malek,Somayeh Ghahremani,Alireza Ataei Nakhaei
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: fennel,Animal,Prolactin,Anthropometric Index,Black seed
- چکیده:
- چکیده انگلیسی: Background: Breastfeeding is the best food for infants. Prolactin is combined with the corresponding receptors on the alveoli that produce milk, and milk production begins. We aimed to review the effect of fennel and black seed on breast milk, prolactin levels and anthropometric index in human and animal samples.
Materials and Methods: After selecting the keywords related to the research question, searching of the online databases (Medline, EMBASE, Scopus, Web of Science, SID and Magiran) were done. After reviewing the retrieved studies based on the title, abstract and full text, and related articles were selected according to the inclusion criteria.
Results: Ten studies were included into review. One study indicated the arousal serum levels of prolactin in lactating mothers using fennel. Four studies showed the fennel as alone or embodied in the herbal tea can increase breast milk. In contrast to the above four studies, a combination of fennel, anise, cumin, dill, parsley and fennel flower had no effect on breast milk volume and neonate weight gain.Two studies inspected the effects of fennel in animal studies. Although 140 and 280 μL doses of fennel have significantly increased prolactin in comparison with 35 and 70 μL g doses, this increment is not sufficient to increase breast milk and, subsequently, to elevate neonates weight with fennel to dairy goats have enhancement and reduction effect, respectively on performance and negative energy balance in early lactation. In another study, black seed improved milk production in cows, while it did not change composition of milk and prolactin.
Conclusion: Based on the results, fennel is recommended to increase breast milk, prolactin levels in lactating women.- انتشار مقاله: 03-12-1398
- نویسندگان: Farzaneh Barkhordari Ahmadi,Amir Pourghorban,Sara Kharghani,Arash Rezaei Shahmirzadi,Seyed Masoud Haghjoyan,Omolbanin Heydari,Fatemeh Babakhanian,Sarah Ghahremani
- مشاهده
- جایگاه : پژوهشی
- مجله: Asia Pacific Journal of Medical Toxicology
- نوع مقاله: Journal Article
- کلمات کلیدی:
- چکیده:
- چکیده انگلیسی:
- انتشار مقاله: 06-03-1395
- نویسندگان: Abdolkarm Hamedi,Alireza Ataei,Mohammad Reza Balali,Somayeh Ghahremani,Sarah Ghahremani
- مشاهده