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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: International Journal of Travel Medicine and Global Health
- نوع مقاله: Journal Article
- کلمات کلیدی: anxiety,Iran,depression,Stress,Psychological distress,coronavirus disease 2019
- چکیده:
- چکیده انگلیسی: Introduction: As the coronavirus disease 2019 (COVID-19) pandemic rapidly sweeps across the world, it is inducing a considerable degree of psychological problems, which can affect everyone in the community. This study aimed to compare the severity of the psychological distress in the general population and patients during the COVID-19 epidemic in an Iranian population.
Methods: In this cross-sectional study, the mental health status of 221 COVID-19 infected patients and 241 participants from general population were investigated by the self-report questionnaire of Depression, Anxiety, and Stress Scale (DASS). The DASS-21 questionnaire and sociodemographic data sheet were filled out by the participants. All statistical analyses were performed using SPSS software version 21.
Results: The results indicated higher scores of DASS in patients than the population simultaneously (Wilks Lambda = 0.934, F (3, 440) = 10.44, p <0.001) and individually (Mean difference [MD] = 2.55, 95% CI = 1.48 to 3.62 for depression, MD = 1.48, 95% CI = 0.39 to 2.57 for anxiety, and MD = 1.41, 95% CI = 0.32 to 2.49 for depression score).
Conclusion: The present study revealed a high prevalence of mental health problems among patients with COVID-19 and gaps in providing them with mental health services. We call for systematic screening of mental health status for all patients and developing specific psychological interventions for this vulnerable population. Psychosocial assessment and monitoring should be developed in the community to support aspects of COVID-19.- انتشار مقاله: 15-08-1399
- نویسندگان: Seyede Momeneh Mohammadi,Sara Ashtari,Masoum Khosh Fetrat
- مشاهده
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: Diagnosis,Prognosis,Survival,long non-coding RNA,PCAT-1
- چکیده:
- چکیده انگلیسی: Long non-coding RNA (lncRNA) prostate cancer associated transcript 1 (PCAT-1) has been identified as a potential
biomarker for the diagnosis and prognosis of various cancers. We performed this systematic review and meta-analysis
to evaluate the role of dysregulation as well as the biological and clinical significance of lnc-PCAT-1 for predicting the
malignancy status in several cancers. Two independent reviewers conducted an extensive search in electronic databases
of Medline, Embase, Scopus, Web of Science and PubMed until the December of 2017. Five articles investigating the
clinical significance of lncRNA PCAT-1, including 996 patients, were analyzed. Our results revealed that the increased
PCAT-1 expression was related to overall survival (OS) (HR = 1.9, 95%CI: 1.13-3.18, P=0.015). Also, pooled results
of the diagnostic data analysis demonstrated that PCAT-1 has a sensitivity of 0.59 and specificity of 0.66 for cancer
diagnosis. Moreover, pooled area under curve was 0.62 (95% CI: 058–0.69). This meta-analysis revealed that lncRNA
PCAT-1 could be served as a potential diagnostic and prognostic biomarker in various solid tumors.- انتشار مقاله: 13-12-1396
- نویسندگان: Atefeh Talebi,Abolfazl Akbari,Gholam Reza Mobini,Sara Ashtari,Mohamad Amin Pourhoseingholi
- مشاهده