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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Asia Pacific Journal of Medical Toxicology
- نوع مقاله: Journal Article
- کلمات کلیدی: drugs,Poisoning,Epidemiology,Traditional Drugs,Synthetic Drugs
- چکیده:
- چکیده انگلیسی: Background: Drug abuse is a global problem in most countries and poisoning caused by them has involved the emergency department (ED). This paper aims to investigate the changes in the epidemiological pattern of poisoned cases due to drugs in Hamadan province of Iran.
Methods: In this five year cross - sectional study, we assessed the epidemiologic pattern of poisoned cases due to drugs hospitalized in Farshchian - Sina Hospital of Hamadan, west Iran from March 2015 to March 2019.
Results: During this period, 7199 poisoned patients referred to hospital and 1773 of them hospitalized due to any kind of drugs.81% were male and 19% were female (p <0.001). The mean age in male cases was 40.85 ± 16.85 and in female cases was 42.37 ± 18.36. 86.4% of the cases lived in urban areas and 13.6% of them lived in rural areas. The most common drugs were opium (33%), methadone (22.7%) and methamphetamine (20.9%). In 35.1% male cases and in 45.8% female cases the most common drugs were opium and methamphetamine, respectively (p <0.001). In 79.2% of cases, overdose and in 20.5% of them, suicide attempt was the most common causes of use. Most cases were alive and only 1.7% were deceased.
Conclusions: Although, poisoning by traditional drugs was still the most common cause of poisoning at the time of the study in this province, poisoning by synthetic drugs are on the rise.
- انتشار مقاله: 09-05-1399
- نویسندگان: Saeed Afzali,Abass Moradi,Hasti Alinaghizadeh
- مشاهده
- جایگاه : پژوهشی
- مجله: Asia Pacific Journal of Medical Toxicology
- نوع مقاله: Journal Article
- کلمات کلیدی: drugs,Poisoning,Epidemiology,Traditional Drugs,Synthetic Drugs
- چکیده:
- چکیده انگلیسی: Background: Drug abuse is a global problem in most countries and poisoning caused by them has involved the emergency department (ED). This paper aims to investigate the changes in the epidemiological pattern of poisoned cases due to drugs in Hamadan province of Iran.
Methods: In this five year cross - sectional study, we assessed the epidemiologic pattern of poisoned cases due to drugs hospitalized in Farshchian - Sina Hospital of Hamadan, west Iran from March 2015 to March 2019.
Results: During this period, 7199 poisoned patients referred to hospital and 1773 of them hospitalized due to any kind of drugs.81% were male and 19% were female (p <0.001). The mean age in male cases was 40.85 ± 16.85 and in female cases was 42.37 ± 18.36. 86.4% of the cases lived in urban areas and 13.6% of them lived in rural areas. The most common drugs were opium (33%), methadone (22.7%) and methamphetamine (20.9%). In 35.1% male cases and in 45.8% female cases the most common drugs were opium and methamphetamine, respectively (p <0.001). In 79.2% of cases, overdose and in 20.5% of them, suicide attempt was the most common causes of use. Most cases were alive and only 1.7% were deceased.
Conclusions: Although, poisoning by traditional drugs was still the most common cause of poisoning at the time of the study in this province, poisoning by synthetic drugs are on the rise.
- انتشار مقاله: 09-05-1399
- نویسندگان: Saeed Afzali,Abass Moradi,Hasti Alinaghizadeh
- مشاهده
- جایگاه : پژوهشی
- مجله: Asia Pacific Journal of Medical Toxicology
- نوع مقاله: Journal Article
- کلمات کلیدی: Addiction,Opium,Blood Lead level
- چکیده:
- چکیده انگلیسی: Background:Raw opium is a kind of drug, abused a lot in Iran. In a vast majority of cases, various impurities including lead are added to raw opium. This study aimed to evaluate Blood Lead Level (BLL) and probable clinical symptoms triggered by it among opium abusers.
Methods:This study was case control and conducted on 40 patients addicted to raw opium (case group) and 40 patients without any kind of addiction (control group) who were hospitalized in the poisoning ward of Farshchian hospital, Hamadan, Iran. BLL was measured by Atomic Absorption Spectroscopy (AAS) and compared between the two groups. Para clinical tests and peripheral blood smear were also assessed to check basophilic erythrocytes.
Results: The patients’ mean age was 51.9±15.8 years in the control group and 53.2±15 years in the case group. Besides, the mean of BLL was 4.02±3.16 µg/dl in the control group and 22.41±21.14 µg/dl in the case group, and the difference was statistically significant (p<0.001). Moreover, routes of exposure included inhalation (72.5%), oral (12.5%), and both (15%). The results indicated no significant associations between the route of exposure and BLL (p<0.281).Furthermore, no special clinical symptoms were observed in most patients in both groups. Nonetheless, anemia and basophilic erythrocytes were detected in 3 patients who had high BLL.
Conclusion:With regard to the high BLL in raw opium abuser, it seems that poisoning with lead should be considered if patients with a history of raw opium addiction refer to physicians.- انتشار مقاله: 02-01-1396
- نویسندگان: Saeed Afzali,Saadat Torabian,Seyed Kazem Taheri
- مشاهده
- جایگاه : پژوهشی
- مجله: Asia Pacific Journal of Medical Toxicology
- نوع مقاله: Journal Article
- کلمات کلیدی: Methadone,Iran,Poisoning,Aged,Opioid-Related Disorders
- چکیده:
- چکیده انگلیسی: Background: A good proportion of poisoned patients treated at poisoning wards are elderly. This study was designed to evaluate the epidemiologic pattern of acute poisoning in elderly in Hamadan, western Iran. Methods: In this retrospective cross-sectional study, poisoned patients aged 60 years and older treated at department of poisoning of Farshchian Hospital from March 2008 to March 2013 were included. Results: In this 5-year period, 7951 poisoned patients were treated at Farshchian Hospital in Hamadan, Iran. Among them, 418 (5.3%) patients were 60 years old or older, with mean age of 71.6 ± 5.1 years. Narcotics and recreational substances were the most common type of poisons responsible for poisoning (46.4%), which among them, methadone was the most commonly used drug (20.3%). Neurologic medicines were the most commonly used pharmaceutical products (16%), among which, benzodiazepines (8.9%) were responsible for the highest number of poisonings due to pharmaceuticals. Fifteen patients (3.6%) including 13 men and 2 women died. The toxic agents used by cases with fatal outcome were opioids (8 patients), organophosphates (5 patients) and aluminum phosphide (2 patients). Men were found to be significantly more affected with recreational substances (P < 0.001) and pesticides (P < 0.001), while poisoning with pharmaceutical products (P = 0.017) was significantly more common in women. Regarding the intention of poisoning, accidental poisoning (P = 0.025) and overdose (P < 0.001) were significantly more common in men while deliberate self-poisoning was significantly more frequent in women (P < 0.001). Conclusion: Deliberate self-harm and poisoning with opioids especially methadone showed a high prevalence in elderly poisoned patients in Hamadan, Iran. It seems that drug trafficking control, addiction rehabilitation therapies and suicide prevention programs for elderly can be helpful in poisoning reduction in this age group in this part of the country.
- انتشار مقاله: 04-08-1394
- نویسندگان: Saeed Afzali,Mohammad Ali Seifrabiei,Seyed Kazem Taheri,Jahangir Pourabdollah
- مشاهده