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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Archives of Bone and Joint Surgery
- نوع مقاله: Journal Article
- کلمات کلیدی: intertrochanteric fracture,Bipolar hemiarthroplasty,Dynamic hip screw
- چکیده:
- چکیده انگلیسی: Background: At present, there is no consensus on an appropriate treatment modality for intertrochanteric fractures in the elderly with background diseases. The aim of the present study was to compare treatment outcomes of intertrochanteric fractures reduced with dynamic hip screws (DHS) and bipolar hemiarthroplasty in elderly patients with background medical conditions.
Methods: In this randomized clinical trial, 60 patients with intertrochanteric fractures, who were 45-60 years old, were randomly divided into DHS and bipolar groups. After treatment, the two groups were compared in relation to complications and mortality rates, functional status using the Harris Hip Score (HHS), range of movement and severity of pain using the visual analogue score (VAS). Results: HHS (86±9 vs. 75±7.6), range of flexion (105±11 degrees vs. 90±17 degrees) and external rotation (35±7 degrees vs. 20±7 degrees) were significantly higher in the bipolar group compared to the DHS group (P<0.05). However, there were no significant differences in pain severity between the two groups.
Conclusion: Reduction of intertrochanteric fractures in elderly patients with background medical conditions is more effective and less problematic with the bipolar technique compared to DHS and is better tolerated by patients, because this technique is associated with improvements in functional status and hip joint movement range.- انتشار مقاله: 25-04-1392
- نویسندگان: Mohammad Emami,Ali Reza Manafi,Behroz Hashemi,Ali Nemati,Saeed Safari
- مشاهده
- جایگاه : پژوهشی
- مجله: Research Journal of Pharmacognosy
- نوع مقاله: Journal Article
- کلمات کلیدی: Rats,Crocus sativus,Saffron,Retina,genetic association studies
- چکیده:
- چکیده انگلیسی: Background and objectives: Crocus sativus L. (Iridaceae) commonly known as saffron, is a popular spice which is used for its pleasant aroma and favored color. Regarding the previous reports about the neuroprotective behavior of saffron or its constituents, in the present work, the neuroprotective property of saffron in rat retina was investigated against light damage in a system biology study. Methods: Retina gene profiles of 4 groups (each group including 3 samples) of rats (control; C light damage; L, Saffron; S, and saffron-light damage; SL) which are included in GSE22818 were extracted from Gene Expression Omnibus (GEO). The significant differentially expressed genes (DEGs) from C-L groups analysis which are not included in S-SL comparison were screened by pathway analysis to find the critical protected genes against light damage by saffron. Results: Numbers of 46 gene were protected by saffron versus light damage significantly. The findings revealed that Casp3, Myd88, Birc3, Tnfrsf1a, Myc, Nfkb2, Fgf2 were the important protected genes by saffron against light damage. “MAPK signaling pathway” and “apoptosis” were highlighted as important related pathways for 46 DEGs. Conclusion: Saffron protects a part of light damage which is controlled mostly by Casp3, Myd88, Birc3, Tnfrsf1a, Myc, Nfkb2, Fgf2. It seems other parts of damage should be studied in more details to find a complete prospective of molecular mechanism of light damage effect on retina.
- انتشار مقاله: 23-11-1398
- نویسندگان: Nayebali Ahmadi,Mohammadreza Razzaghi,Maryam Hamzeloo-Moghadam,Mohammad Rostami-Nejad,Majid Rezaei-Tavirani,Mohammad Hossein Heidari,Saeed Safari,Mostafa Rezaei-Tavirani*
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Information Technology Management
- نوع مقاله: Journal Article
- کلمات کلیدی: MCDM,E- Marketing Effectiveness,E-Quality,E-Branding
- چکیده:
- چکیده انگلیسی: The main purpose of this study was to propose a model for assessing the effectiveness of web-based marketing in Iran's airline industry. Thence in the first step after identifying the components of the model on the basis of literature review and opinions of experts in the field of marketing and sales related to airline industry, the final components of the model were extracted .In the second step, the Dematel method has been used to determine the existing relations between criteria. In the following, we utilized the ANP to determine the weight of each criterion with regard to the existing dependency and feedback between criteria as the third step. Finally in the last step of this research three reputable Iranian Companies in the airline industry were ranked by the use of VICTOR method. The results obtained by Dematel method indicated the internal and external communications between criteria of the assessing effectiveness of web-based marketing model. Meanwhile, the results of ANP suggested that “Reliability” was in the first place in terms of weight and importance among all criteria of the model. Result of VICOR showed that Mahan Company had the minimum distance to the ideal level.
- انتشار مقاله: 15-09-1394
- نویسندگان: Saeed Safari,Reyhaneh Helali
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Information Technology Management
- نوع مقاله: Journal Article
- کلمات کلیدی: Quality Management,Information Technology,Central Insurance of Iran,Quality Management Process
- چکیده:
- چکیده انگلیسی: In this research we investigate the effects of information technology on quality management processes in the Central Insurance organization of Iran. The research is an applied one, using correlation method. The population of the research includes the personnel of the organization of Central Insurance of Iran which are more involved by using information technology. These personnel are mostly from accounting and finance, research and development, human resources, computer and network units. A sample of 83 employees was randomly selected and a questionnaire was used to gather and measure the answers. Findings showed that all of the elements of quality management in organizations are affected by information technology because the organization’s processes are highly based on information. In this research main hypothesis was significantly accepted and also IT has the most effect on customer satisfaction. For executive managers in Central Insurance organization, the last finding has an important result, because they can make customers satisfied by facilitating information processes and solving problems that may be faced within the organization.
- انتشار مقاله: 11-10-1348
- نویسندگان: Saeed Safari,Safieh Shirzad,Hassan Khalili
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Emergency Practice and Trauma
- نوع مقاله: Journal Article
- کلمات کلیدی: treatment,COVID 19,thromboembolism
- چکیده:
- چکیده انگلیسی: The coronavirus disease 2019 (COVID-19) was first emerged from Wuhan, China, in late 2019, and has since been spreading progressively all around the world. Its prevalence is climbing increasingly and almost all countries worldwide are confronting this pandemic. As of April 11, 2020, reports obtained about the management of COVID-19 patients indicate that the mortality rate of the disease is around 5% with consideration of the active cases and 21% of the closed cases
- انتشار مقاله: 20-02-1399
- نویسندگان: Saeed Safari,Mahmoud Yousefifard
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Emergency Practice and Trauma
- نوع مقاله: Journal Article
- کلمات کلیدی: Hyperkalemia,Complete heart block,External pacing
- چکیده:
- چکیده انگلیسی: Background: Potassium, as an extracellular ion, plays an important role in the electrophysiologic function of the myocardium and any change in extracellular concentration of this ion might have a marked impression upon myocyte electrophysiologic gain. High serum potassium levels are thought to impair pulse conduction in Purkinje fibers and ventricles more than that in the Atrioventricular (AV) node. Therefore, although complete AV block can occur, it is a rare initial presentation.
Case Report: We describe a 62-year-old man with a history of diabetes mellitus, ischemic heart disease and previous Coronary Artery Bypass Graft (CABG), who came to our emergency department due to generalized weakness starting 2 days before admission. The patient also had decreased force in lower limbs, exacerbating from the morning, and was finally diagnosed as a hyperkalemia-induced Complete Heart Block (CHB). It should also be noted that the patient responded dramatically to the administration of 10 mL of 10% calcium gluconate along with external pacing until potassium level correction became effective.
Conclusion: In spite of the fact that Hyperkalemia can be associated with frequent Electrocardiogram (ECG) abnormality, advanced heart blocks (second- and third-degree AV blocks) are usually found only in patients with pre-existing heart failure, conduction abnormalities, or other cardiac diseases. Institution of effective treatment rapidly and forgiveness of traditional non-effective, time consumptive and sometimes risking full-adjustment modalities, such as sodium bicarbonate infusion or exchange resins that prevent their use in the emergent phase, can help minimize patient morbidity and mortality.- انتشار مقاله: 15-01-1394
- نویسندگان: Alireza Baratloo,Pauline Haroutunian,Alaleh Rouhipour,Saeed Safari,Farhad Rahmati
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Emergency Practice and Trauma
- نوع مقاله: Journal Article
- کلمات کلیدی: Neonatal problems,Outcomes of labour,Ethnic differences
- چکیده:
- چکیده انگلیسی: Objective: There are major differences in neonatal and obstetrics outcomes of labour among different ethnicities. The present study compared the neonatal and obstetrics outcomes of labour between the Iranian and Afghan ethnicities.
Methods: Neonatal and obstetrics problems were evaluated in Iranian and Afghan pregnant women, who had referred to Arash Educational/Treatment Center for labour during a year.
Results: 3020 (93.7%) Iranian and 202 (63%) Afghan women were evaluated. There were no significant differences between the two ethnicities in relation to a need for Neonatal Intensive Care Unit (NICU), the rate of live births, infant birth weight, congenital anomalies and premature births (P>0.05). The rate of Caesarian section was higher in Iranian women (P=0.001).
Conclusion: It seems that the differences in neonatal problems and outcomes of labour obstetrics between Iranians and Afghans can be attributed to different cultural, economic, and social conditions in comparison to different ethnicities.- انتشار مقاله: 15-01-1394
- نویسندگان: Aboutaleb Beigi,Alireza Mazinanian,Mansour Ashrafinia,Alireza Baratloo,Saeed Safari
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Advances in Medical Education and Professionalism
- نوع مقاله: Journal Article
- کلمات کلیدی: Medical students,Education,Medical assessment
- چکیده:
- چکیده انگلیسی: Introduction: Clinical reasoning as a critical and high level of clinical competency should be acquired during medical education, and medical educators should attempt to assess this ability in medical students. Nowadays, there are several ways to evaluate medical students’ clinical reasoning ability in different countries worldwide. There are some well-known clinical reasoning tests such as Key Feature (KF), Clinical Reasoning Problem (CRP), Script Concordance Test (SCT), and Comprehensive Integrative Puzzle (CIP). Each of these tests has its advantages and disadvantages. In this study, we evaluated the reliability of combination of clinical reasoning tests SCT, KF, CIP, and CRP in one national exam and the correlation between the subtest scores of these tests together with the total score of the exam.
Methods: A total of 339 high ranked medical students from 60 medical schools in Iran participated in a national exam named “Medical Olympiad”. The ninth Medical Olympiad was held in Shahid Beheshti University of Medical Sciences, Tehran, Iran, under the direct supervision of the Ministry of Health and Medical Education in summer 2017. The expert group designed a combination of four types of clinical reasoning tests to assess both analytical and non-analytical clinical reasoning. Mean scores of SCT, CRP, KF, and CIP were measured using descriptive statistics. Reliability was calculated for each test and the combination of tests using Cronbach’s alpha. Spearman’s correlation coefficient was used to evaluate the correlation between the score of each subtest and the total score. SPSS version 21 was used for data analysis and the level of significance was considered <0.05.
Results: The reliability of the combination of tests was 0.815. The reliability of KF was 0.81 and 0.76, 0.80, and 0.92 for SCT, CRP, and CIP, respectively. The mean total score was 169.921±41.54 from 240. All correlations between each clinical reasoning test and total score were significant (P<0.001). The highest correlation (0.887) was seen between CIP score and total score.
Conclusion: The study showed that combining different clinical reasoning tests can be a reliable way of measuring this ability.- انتشار مقاله: 14-02-1398
- نویسندگان: ANAHITA SADEGHI,ALI ALI ASGARI,NEZARALI MOULAEI,VAHID MOHAMMADKARIMI,SOMAYEH DELAVARI,MITRA AMINI,SETAREH NASIRI,ROGHAYEH AKBARI,MOJGAN SANJARI,IRAJ SEDIGHI,PARISA KHOSHNEVISASL,MANOUCHEHR KHOSHBATEN,SAEED SAFARI,LEILY MOHAJERZADEH,PARISA NABEIEI,BERNARD CHARLIN
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: Emergency Service,Pediatrics,Sensitivity and Specificity,Decision support systems
- چکیده:
- چکیده انگلیسی: Background: The present study assesses independent predictors of clinically important traumatic brain injury (ciTBI) in order to design a prognostic rule for identification of high risk children with mild head injury. Materials and Methods: In a retrospective cross-sectional study, 3,199 children with mild traumatic brain injury (TBI) brought to emergency ward of three hospitals in Tehran, Iran were gathered, from April 2014 to April 2016. The associations between probable predictors of ciTBI in children with mild TBI were assessed and a prediction rule for identification of high risk children in need of computed tomography (CT) scan was designed based on a stepwise multivariate logistic regression. Results: 592 (18.5%) children had ciTBI. History of loss of conciseness (odds ratio [OR]=3.0; p<0.0001), underlying disease (OR=3.6; p=0.002), Glasgow coma scale (GCS) score equal to 14 (OR=40.6; p<0.0001), altered mental status (OR=19.1; p<0.0001), need for intubation (OR=27.4; p<0.0001), presence of vomiting (OR=7.3; p=0.001), and sign of basilar skull fracture (OR=25.9; p=0.007), were the most important prognostic factors of ciTBI in children. Pediatric traumatic brain injury prognostic rule (PTBI prognostic rule) was designed based on these predictors. PTBI prognostic rule had an area under the curve of 0.93, a sensitivity of 100.0%, a specificity of 73.0% and a proper calibration (slope=0.97 and intercept=0.006) in identification of ciTBI. Conclusion: The present study showed that a few of children with mild TBI have ciTBI. Therefore, CT scans are not necessary in all of these children. Using PTBI prognostic rule can reduce the number of unnecessary CT scans.
- انتشار مقاله: 27-09-1395
- نویسندگان: Babak Nakhjavan-Shahraki,Mahmoud Yousefifard,Alireza Oraii,Arash Sarveazad,Mohammad Javad Hajighanbari,Saeed Safari,Alireza Baratloo,Abbas Tafakhori,Mostafa Hosseini
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: Pregnancy,Methotrexate,Beta Subunit,Chorionic Gonadotropin,Ectopic
- چکیده:
- چکیده انگلیسی: Background: No consensus has been reached on prognostic value of serum concentration of β (beta) subunit of human chorionic gonadotropin (β-hCG) in treatment response to methotrexate in management of ectopic pregnancy. Therefore, the present study aimed to evaluate this subject through a systematic review and meta-analysis.
Materials and Methods: An extensive literature search on online databases was performed. All studies performed on ectopic pregnancy patients treated by methotrexate from all age groups were included. After collecting data, random effect models were used to calculate the pooled standardized mean difference (SMD) of β-hCG level in treatment success and treatment failure groups. Finally, pooled performance screening characteristics of serum β-hCG level were assessed in different cut offs.
Results: Finally, 51 articles were included in meta-analysis. Overall treatment success rate of methotrexate was 84% [95% confidence interval (CI): 84-85 percent]. A negative association was found between serum β-hCG level and the treatment response before intervention (SMD= -1.10, 95% CI: -1.39 to -0.88). In addition, pooled sensitivity, specificity, and prognostic odds ratio of β-hCG in the 2000 mIU/mL cut off were: 0.75 (0.65-0.82), 0.68 (0.58-0.82), and 6.0 (5.0-8.0), respectively.
Conclusion: The present meta-analysis showed that serum β-hCG concentration before treatment could predict success of methotrexate in management of ectopic pregnancy.- انتشار مقاله: 01-06-1395
- نویسندگان: Parisa Ghelichkhani,Mahmoud Yousefifard,Lyly Nazemi,Saeed Safari,Mostafa Hosseini,Masoud Baikpour,Samira Salamati Ghamsari,Mehdi Yaseri
- مشاهده