در هنگام جستجو کلمه در قسمت عنوان میتوانید کلمات مورد جستجو را با کاراکتر (-) جدا کنید.
کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Research Journal of Pharmacognosy
- نوع مقاله: Journal Article
- کلمات کلیدی: Iranian Traditional Medicine,dry skin,qeirooti,skin fissure
- چکیده:
- چکیده انگلیسی: Dry skin is a common problem which affects wound healing, severity of other skin diseases and quality of life of people. One of its undesirable effects is fissure that is a cutaneous condition in which there is a linear loss of epidermis and dermis with sharply defined, nearly vertical walls. In the present study, we have investigated the etiology of the disease and its treatments in conventional medicine and Iranian Traditional Medicine (ITM). Two traditional medicine references, current scientific data bases and medicinal texts were explored with the selected keywords such as "sheqaq-e-poosti", "skin fissure" and "dry skin" to find the etiology and treatment of skin fissure. From the view point of both conventional medicine and ITM, dry skin is the cause of skin fissure and some causes of dry skin are similar. In conventional medicine, moisturizers are mainly used for treatment of dry skin; while in ITM some herbs, oils and other natural remedies have been used. A topical dosage form which was called "qeirooti", a mixture of wax and oil, was used to treat skin fissure in ITM. It comprised of oily ingredients that acted as occlusives and also some herbal components that directly improved dry skin (similar to moisturizers). Components efficacy of traditional dosage forms for treatment of dry skin lead us to study about formulation of “qeirooti” for treatment of dry skin.
- انتشار مقاله: 18-11-1393
- نویسندگان: A. Jedkareh,S. Esmaeili,A. Alembagheri,S.A. Mortazavi
- مشاهده
- جایگاه : پژوهشی
- مجله: Research Journal of Pharmacognosy
- نوع مقاله: Journal Article
- کلمات کلیدی: Antioxidant,Anti-inflammatory,Anti-bacterial,Iranian Traditional Medicine,burn healing
- چکیده:
- چکیده انگلیسی: Burns are known as one of the most common forms of injury with devastating consequences. Despite the discovery of several antiseptics, burn wound healing has still remained a challenge to modern medicine. Herbal products seem to possess moderate efficacy with no or less toxicity and are less expensive compared to synthetic drugs. Burn is a well-known disorder in Iranian Traditional Medicine (ITM). Iranian physicians have divided burns into various types based on the cause and recommended treatment for each type. According to ITM references, herbal therapy was the major treatment prescribed by Iranian physicians for burns. In the present study, seven ancient Iranian medical texts were screened for the herbs with burn healing effects along with their applied dosage forms. The medicinal herbs were listed and scored based on the frequency of their repetition. Moreover, the best scientific name that was suitable for each plant as well as surveying modern studies about their biological effects has been carried out. In our investigation eighteen plants with seven topical application categories have been obtained as the most frequent herbs for burn healing in ITM. Modern studies have revealed that these plants have shown some biological activities such as anti-inflammatory, antimicrobial and antioxidant effects which might establish the relationship between the mentioned activities and burn wound healing property. This list can provide a suitable resource for future researches in the field of burn treatment.
- انتشار مقاله: 07-06-1393
- نویسندگان: Sh. Fahimi,H. Hajimehdipoor,M. Abdollahi,S.A. Mortazavi
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Kerman University of Medical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: Sodium alginate,Carrageenan,Carbopol 934P,mucoadhesive strength,Sodium carboxymethyl cellulose,polythylene oxide,Karaya
- چکیده:
- چکیده انگلیسی: Mucoadhesive durg delivery systems are among novel drug delivery systems that due to their ability to adhere and remain on the mucosal surfaces and a show and sustained release of their drug contect have attracted special attention in recent years.the aim of this study was to evaluate the effect of four different important factors on the mucoadhesive strength of a few mucoadhesive polymers.among the polymers investigated apart from the known polymers such as Carbopol 934P(C934) and sodium carboxymethyl cellulose(CMC) which have high mucoadhesive strengths,the effectiveness nof a few other polymers were also studied.these were polyethylene oxide(PEO),karaya(Kar),carrageenan(Carr) and sodium alginate(Na alg).for this purpose polymer containing discs were prepared and their mucoadhesive strength in rat intestine (as a mucose model) was assessed by using a home made apparatus.the mucoadhesive strength of prepared polymeric discs in the presence and obsence of phosphate buffer PH=6.0 at 37C and at various PH values from 2.2-8.0 and under the condition of hydrating the polymeric discs for 2 and 5 minutes in phosphate buffer PH=6.0 before placing them in contact with mucosa,was evaluated .also the effect of uera (as the hydrogen bond breaker) on the mucoadhesive strength of discs contatining C934 and PEO was evaluated.the results showed that among the polymers studied,PEO and Carr like C934 and CMC have desirable mucoadhesive strengths ,and could be used for the preparation of mucoadhesive drug delivery systems.it was also found that the extent od hydration of polymer containing discs has an important effect on their mucoadhesive strength.strength in case of insufficient polymer hydration or its overhydration,the mucoadhesive strength will be greatly reduced.also,the environmental PH has an important effect on the mucoadhesive strength of discs and therefore in the desing of a mucoadhesive system,a polymer whit a high mucoadhesive strength in the specific area of the boys should be used.Furthermore it was found that the formation of hydrogen bonds between the mucoadhesive polymer and mucose,plays a very important role min the fprmation of a strong mucoadhesive bond.
- انتشار مقاله: 18-07-1395
- نویسندگان: S.A.R Mortazavi,S.A.R Mortazavi,S.A.R Mortazavi
- مشاهده