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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: International Journal of Engineering, Transactions A: Basics
- نوع مقاله: Journal Article
- کلمات کلیدی: Genetic programming,Asphalt Mixture,Creep,Visco,elastic Model,Generalized Model
- چکیده:
- چکیده انگلیسی: The analysis of pavements and their ingredients has always been important due to a good understanding of their behavior under different conditions; that leads to more accurate relations. Due to the extent of asphalt mixture application in the world, the assessment of different behaviors of this mix is very important from various aspects of performance and safety. Given that the asphalt mixtures are inherently very sensitive to temperature changes due to bitumen content, identification and analysis of the viscoelastic and visco-elasto-plastic behavior of the mixture is of particular importance. The scope of present research is to provide new model of viscoelastic behavior of asphalt concrete pavements with a combined effect of stress and temperature using genetic programming techniques. For this purpose, a number of dynamic creep tests under various temperatures and different stress levels were done. Beside, in this study a comparison is made between the generalized model and proposed model in estimating the visco elastic response of asphalt samples. Performance of the genetic programming model is quite satisfactory. The new proposed model will also help further researchers willing to perform similar studies, without carrying out destructive tests.
- انتشار مقاله: 11-10-1348
- نویسندگان: S. M. Mirabdolazimi,G. A. Shafabakhsh
- مشاهده
- جایگاه : پژوهشی
- مجله: Archives of Razi Institute
- نوع مقاله: Journal Article
- کلمات کلیدی: genotyping,Foot and Mouth Disease virus,serotype A,phylogenetic
- چکیده:
- چکیده انگلیسی: The foot-and-mouth disease virus (FMDV) with a wide variety of genomes and complicated biology is one of the infectious agents that put the lives of animals at risk. Therefore, to introduce suitable strains for vaccine production, it is essential to constantly evaluate genetic changes of circulating viruses in field. Within 2014-2015, a total of 126 clinical specimens consisting of epithelial tissue and vesicular fluid from tongue, dental pad, and hoofs suspected of FMD virus were submitted to the Reference Laboratory for FMD in Razi Vaccine and Serum Research Institute, and 86 of them were identified as FMD virus type A using sandwich Enzyme-Linked Immunosorbent Assay (ELISA). This virus was isolated from 42 samples from 16 provinces using cell culture. Firstly, the coding region that produces the main part of viral capsid was amplified by Polymerase chain reaction (PCR). This part of the genome by 800 bp length was related to the 1D gene that synthesizes the VP1 protein. The phylogenetic analysis of VP1 coding region determined two distinct genotypes with more than 15% nucleotide differences. The first cluster consisted of closely related viruses registered in the GeneBank of neighboring countries, including Afghanistan, Pakistan, and Turkey. All samples in Cluster1 were determined as relative viruses with genotype Iran-05. In-vitro serological examination indicated an antigenic relationship between Cluster 1 viruses and routine vaccine strain (A-IRN-2013). The second cluster with only two members was genetically far from earlier ones and could be considered a separate genotype. Furthermore, it was revealed that cluster 2 has not been previously reported in Iran. Genetic tracing indicated that these viruses might have been originated from circulating viruses from India. Antigenic evaluation exhibited that this group could not be cross-protected by the routine vaccinal strain (A-IRN-2013) used during the research period.
- انتشار مقاله: 09-10-1397
- نویسندگان: S. M. Azimi,H. Mahravani,M. Lotfi
- مشاهده