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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: Pap smear,cervical cancer screening,LMIC
- چکیده:
- چکیده انگلیسی: Introduction: India fights massive cervical cancer burden. This article highlights an innovative feasible approach
enabling tertiary hospitals to contribute to cancer prevention without compromising their primary mandate to provide
treatment. Methodology: Since 1979, National Institute of Cancer Prevention and Research (NICPR) support a tertiary
hospital in cervical cancer screening through a satellite clinic. Record review of 5328 attendees of this clinic between
January-December 2016 was done. Pap-smear testing and reporting were performed by trained NICPR personnel. Patients’
demographics, reproductive history, Pap-test date, cytology results were recorded and results were communicated to
respective units for further management. Results: Among 5328 women screened, 2% (96/5328) had abnormal cytology,
which included malignancy(33%; 32/96), Atypical Squamous Cells-Undetermined Significance(ASC-US) (20%;
19/96), Atypical Glandular Cells(AGC) (23%; 22/96) with complaints of pain in lower abdomen 65.6%(59/90), white
discharge per vaginum 46.7%(42/90) and backache 23.3%(21/90). In which, Muslims- 67% (65/96), illiterates- 58%
(56/96). Age>35(p<0.001), parity>3(p<0.05), illiteracy (p<0.05), Muslim women (p<0.05) had positive association with
abnormal cytology. Conclusion: Awareness about cervical cancer screening is the immediate need in resource-limited
countries. Government hospitals in such countries should house dedicated preventive oncology unit for cancer screening.- انتشار مقاله: 26-10-1397
- نویسندگان: Kavitha Dhanasekaran,Chandresh Verma,Vipin Kumar,Roopa Hariprasad,Ruchika Gupta,Sanjay Gupta,Ravi Mehrotra
- مشاهده
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: Screening,Vaccination,cervical cancer,low resource settings,HPV
- چکیده:
- چکیده انگلیسی:
Cervical cancer continues to be a major public health problem affecting large numbers of women in many developing countries. Limitations of various screening modalities and the lack of ready availability of a cost-effective point-of-care screening tool have hindered the efficient implementation of population-based screening programs in these settings. It has not proved possible for many countries to adopt cytology as a screening modality due to inadequate infrastructure and trained manpower. However, recent developments, notably design and testing of a low-cost HPV test kit and initiatives by countries like India in developing and putting into operation a framework for large-scale screening of women, have raised hopes that cervical cancer control may be possible even in resource-constrained locations. With the advent of HPV vaccination, primary prevention of cervical cancer also seems a distinct possibility. However, wide availability and acceptability of vaccination is still an unresolved issue for developing countries. The possible future effects of vaccination on test characteristics of various screening strategies also need to be evaluated. This review gathers information on the current status of cervical cancer screening with a special focus on low resource settings. It revisits the strengths and limitations of the available screening modalities for cervical cancer viz. cytology, visual methods and HPV testing, in the context of their applicability in developing countries. In addition, the role of newer HPV-detection methods, for instance DNA, RNA and protein-based techniques, in triage of screen-positive women is discussed. The contemporary issue of impact of HPV vaccination on cervical cancer screening is also addressed briefly. The main highlight of the review is the reference to ‘operational framework guidelines’ for population-based cervical cancer screening, which have recently been formulated and are in the process of being implemented in India. The guidelines may serve as a model for other similar low-resource settings where implementation of cancer screening is desired.- انتشار مقاله: 14-11-1395
- نویسندگان: Ruchika Gupta,Sanjay Gupta,Ravi Mehrotra,Pushpa Sodhani
- مشاهده