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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Iranian Journal of Immunology
- نوع مقاله: Journal Article
- کلمات کلیدی: Single Nucleotide Polymorphism,Basal cell carcinoma,Interkulein-17
- چکیده:
- چکیده انگلیسی:
- انتشار مقاله: 23-12-1397
- نویسندگان: Kasra Mohammadipour,Reza Mansouri,Rahmatollah Salmanpour,Mohammad Reza Haghshenas,Nasrollah Erfani
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Immunology
- نوع مقاله: Journal Article
- کلمات کلیدی: Cytokines,ELISA,Preeclampsia
- چکیده:
- چکیده انگلیسی: Background: Preeclampsia is a major cause of mortality and morbidity and is also a leading cause of preterm birth and intrauterine growth retardation. Several studies have reported abnormal levels of cytokines in women with preeclampsia.
Objectives: To detect serum levels of various cytokines in pregnant women with and without preeclampsia in the third trimester of pregnancy.
Methods: Thirty patients with preeclampsia and thirty normal pregnant women were enrolled in the study. Blood samples were taken and serum levels of IFN γ, IL-12p70, IL-18, IL-15, IL-4 and IL-10 were measured by enzyme-linked immunosorbent assay (ELISA).
Results: Preeclamptic women had significantly increased levels of circulating IL-12p70 (p < 0.05), IL-18 (p < 0.001), IL-4 (p < 0.001), IL-15 (p < 0.05) and IFN γ (p < 0.001). By contrast, circulating levels of IL-10 were not significantly different between the two groups.
Conclusions: The present study supports the hypothesis of altered immune response in preeclampsia and suggests that dysregulation of cytokine expression occurs in preeclampsia with increased levels of IFN γ, IL-12p70, IL-15, IL-18 and IL-4.- انتشار مقاله: 17-05-1395
- نویسندگان: Reza Mansouri,Firoozeh Akbari,Mohammad Vodjgani,Fereidoun Mahboudi,Fathollah Kalantar,Mahroo Mirahmadian
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Web Research
- نوع مقاله: Journal Article
- کلمات کلیدی: Social network,Segregation,Opinion Formation,Opinion Dynamics,Social Impact Model, Agent-Based Modeling
- چکیده:
- چکیده انگلیسی: Knowing the current public opinion and predicting its trend using opinion formation models is very applicable. The social impact model of opinion formation is a discrete binary opinion model. It describes how interactions among individuals and sharing their opinions about a specific topic in a social network affect the dynamics of their opinions and form the opinion of society. The society could be an online social network. In this research, we considered the effect of segregation on opinion formation. Segregation is a phenomenon that happens due to homophily and is measured based upon network topology. Homophily is the tendency of individuals to interact with others who share similar traits. We used scale-free networks to model interactions between individuals. The social impact model includes a noise parameter, which is the stochastic part of the model, dealing with the inexplicable behavior of individuals and the effects of other influentials, e.g., mass media. Since this noise is a white noise with no bias toward any possible opinion, for simplicity, we assumed a noise-free social impact model, which is valid in equilibrium analysis we considered. The results reveal that with the same attributes for the individuals, the more segregated opinion group dominates the less segregated opinion group on average. Therefore, with the same population size and individual characteristics of both opinion groups, segregation is an overall influential factor for opinion formation. A more segregated opinion group attracts some individuals from the other group and becomes the majority opinion group of society in equilibrium.
- انتشار مقاله: 21-01-1399
- نویسندگان: Alireza Mansouri,Fattaneh Taghiyareh
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: anxiety,Infant,Mother,Neonatal Intensive Care Unit,Preterm
- چکیده:
- چکیده انگلیسی: Background: Preterm birth and subsequent admission of the infant to neonatal intensive care unit (NICU) can be distressing for parents and lead to their anxiety. The aim of this study was to evaluate maternal anxiety in mothers of infants admitted to the NICU and determine the characteristics associated with maternal anxiety.
Materials and Methods: This study is a descriptive, cross-sectional study with participation of 100 mothers with infant that was born premature and hospitalized in NICU (mothers were selected through convenient sampling method) of Al-Zahra hospital, affiliated to Tabriz University of Medical Sciences, Tabriz, Iran. Data collection tools included baseline characteristics (21 items), and Spielberger State-Trait Anxiety Inventory (STAI). Data were analyzed using SPSS software (version 23.0).
Results: The results of study showed that 62% (n=100) of mothers had moderate level of state anxiety and (54% (n=100) had moderate level of trait anxiety, mean (SD) state anxiety score was 48.62(6.00) and mean (SD) trait anxiety was 32.45(3.63. There was statistically significant difference regarding state anxiety mean scores and number of delivery, education level, gestational age at birth weeks and child order (P<0.05).
Conclusion: Based on the results, mother of premature infants had moderate level of state anxiety. Having university degree, the mothers whose premature infants were at 33 weeks gestational age and mothers who had third or more delivery number and their child order was third and over had experienced state anxiety.- انتشار مقاله: 20-03-1398
- نویسندگان: Zhilla Heydarpoor Damanabad,Leila Valizadeh,Mohamadreza Mansouri Arani,Mohammadbager Hosseini,Mohammad Asgari Jafarabadi,Morteza Mansourian,Arash Ziapour,Omid Safari,Amin Mirzaei,Babk Rastegarimehr
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: risk factors,Pregnancy,Infant,fetus,Prenatal care,Premature
- چکیده:
- چکیده انگلیسی: Background: Preterm birth is one of the most remarkable reasons for neonatal and infant mortality and morbidity across the world. This study aimed to determine risk factors of premature infants in the rural area of Azadshahr city, Iran. Materials and Methods: Acase-control study was conducted on all premature and low birth neonates (less than 37 weeks and weight less than 2500 grams). Data were collected by records in 30 health houses located in the rural areas of Azadshahr city durring 2013 to 2016. Two groups (case and control) were matched by gender and health houses. A trained midwife was collected data by using of a researcher-made checklist. To describe mean and standard deviation of the demographic characteristics, descriptive methods were used.To analyze, inferential statistic tests such as Chi- square, and independent t-test were implemented through SPSS (version,16). Significant level was also taken <0.05. Results: In total, 112 girl infant and 101 boy infant were explored. The mean age of mother in the case and control groups was 26.14+ 8.4 and 25.67+ 9.1 years old respectively.There was a significant difference between the two groups in terms of prenatal care and pregnancy complications. In addition, a remarkable relations was found between polytocous and delivery time (P<0.05). Conclusion: Providing mothers with necessary information in terms of interval between births, and the importance of prenatal cares in the pregnancy period to prevent complication seems to be likely useful.
- انتشار مقاله: 30-03-1395
- نویسندگان: Marzieh Gorzin,Morteza Mansourian,Abdurrahman Charkazi,Hassan Rahimzadeh,Aref Rezaee Node,Mostafa Qorbani,Omid Safari,Babak Rastgari Mehr,Hamid Asayesh,Mohammadreza Mansouri Arani,Hossein Ansari,Tahereh Pashaei,Hesamedin Hesamedin Askari Majdabadi,Kamal Mirkarimi
- مشاهده
- جایگاه : پژوهشی
- مجله: Advanced Herbal Medicine
- نوع مقاله: Journal Article
- کلمات کلیدی: fennel,Asafetida,Ginseng,4T1 Cell line,Breast cancer
- چکیده:
- چکیده انگلیسی: Background: The 4T1 cells tumor growth and metastatic pattern in BALB/c mice very closely mimic human breast cancer. These herbal remedies used in traditional folk medicine have been the source of many medically beneficial drugs. The aim of the current study was to evaluate the anti-proliferative activity of the asafoetida, ginseng and fennel ethanolic extracts on mouse breast cancer 4T1 cell-line invitro.Method: in this experimental study, Asafoetida, gensing and fennel were extracted; 4T1 mouse mammary tumor cell line were cultured in 48-well flat bottom plate in density of 50x103 per well in 100 µl RPMI1640 medium then different dilutions of each extract (25 , 50, 100, 200, 500, and 2000 μg/ml) were added to cell culture. Cells then were incubated at 37 oC for 24 hours. After 24 h, cell Proliferation was determined by the BRDU assay . dataset of experiments were collected and analysed with SPSS19 software. Significant level of Data was Examined with one-way ANOVA method and P
- انتشار مقاله: 13-11-1393
- نویسندگان: Amir Hossein Mansourabadi,Ali Shams,Reza Mansouri,Ahmad Najafi,Maryam Ajami
- مشاهده