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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Journal of Nutrition,Fasting and Health
- نوع مقاله: Journal Article
- کلمات کلیدی: Non-Alcoholic fatty liver disease,Anthropometric,FibroScan,Hepatic steatosis,transient elastography
- چکیده:
- چکیده انگلیسی: Introduction: Non-alcoholic fatty liver disease (NAFLD) is an important health problem globally that characterized as a disease spectrum which includes simple steatosis, non-alcoholic steatohepatitis and liver fibrosis and cirrhosis. The prevalence of NAFLD has significantly increased recently. The aim of this study was to investigate the relationship between anthropometric parameters and hepatic steatosis.Methods: This cross-sectional study was performed on 415 eligible participants. Anthropometric parameters were evaluated by standard methods and fat mass was measured with bioelectrical impedance analysis. Hepatic steatosis was diagnosed using FibroScan.Results: Of the 415 participants, 308 (74.2%) had hepatic steatosis. Body mass index and waist circumference were significantly higher in patients with hepatic steatosis. Hepatic steatosis had a significant and positive association with WC, body fat mass, and trunk fat mass. The trunk fat mass had the highest association with hepatic steatosis. Conclusion: The present study demonstrated that anthropometric measurements are related to increase hepatic steatosis even after adjustment for age and weight.
- انتشار مقاله: 08-04-1398
- نویسندگان: Maryam Ghandehari,Zahra Dehnavi,Farkhondeh Razmpour,Mahsa Miryan,Davood Soleimani,Seyed Mostafa Parizadeh,Reza Jafarzadeh Esfehani,Majid Sedaghat,Habibollah Esmaily,Mohsen Nematy
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Nutrition,Fasting and Health
- نوع مقاله: Journal Article
- کلمات کلیدی: Iran,Stomach neoplasms,Cardia, Pathology
- چکیده:
- چکیده انگلیسی: Introduction: The global incidence of gastric cancer (GC) has been decreased dramatically in recent decades and characteristics of this cancer has been changed. Most of these changes can be resulted from changes in dietary and nutritional habits. This cancer is the most common cancer in north and northeast of Iran. In present report we will briefly summaries the gastric tumor location in a population from north east of Iran. Methods: We have evaluated the stomach tumors location according to patient’s gender and age. Among 212 Iranian patients who were lived in Mashhad, Iran, the cardia was the most common involved anatomic location. There wasn’t any significant relation between patient gender and tumor location as well as patient age and tumor location. Results: According to our results, the incidence of gastric cancer in patients who are aged between 60 to 69 years is decreasing in our population while the most common anatomic site of tumor remains the same. Conclusion: By knowing the most prevalent tumor site and related risk factors, more precise diagnostic and preventing programs can be established. Increasing global awareness about the risk factors of GC seems to be the main reason and efforts should be made to speed up this issue.
- انتشار مقاله: 09-08-1397
- نویسندگان: Seyed Mostafa Parizadeh,Reza Jafarzadeh Esfehani,Maryam Ghandehari,Afsaneh Rezaei Kalat,Anahita Masoom,Mohammad Reza Farzaneh Far
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Midwifery and Reproductive Health
- نوع مقاله: Journal Article
- کلمات کلیدی: Ileus,Chewing gum,Caesarean section
- چکیده:
- چکیده انگلیسی: Background & aim: Cesarean section (CS) accounts for 35% of all surgical operations in Iran. Post cesarean ileus is a complication of CS. There are various pharmaceutical and non-pharmaceutical ways for the treatment of this condition. Given the fact that the non-pharmaceutical approaches are better tolerated and often inexpensive, the present study was conducted to evaluate the effect of chewing gum on post cesarean ileus.
Methods: This clinical trial was conducted on 93 patients undergoing CS (i.e., elective or urgent CS) at Sabzevar Mobini Hospital, Savzevar, Iran, between July 2013 and September 2014. The study population was selected using convenience sampling technique and assigned into two groups of chewing gum (n=35) and control (n=58) groups. The subjects in the chewing gum group were encouraged to chew gum at defined intervals. Both groups were evaluated for pain, bowel sounds, first defecations, gas passage, and feeling bowel movements. Data analysis was performed in SPSS software, version 21.
Results: There was no significant difference between the two groups in terms of the auscultation of first bowel sound, first record of gas passing, and first defecation. The logistic regression models showed that chewing gum was significantly associated with reduced post-operative pain while controlling for surgery duration as a confounding factor (OR: 0.79, 95% CI for OR=0.63, 0.99). However, chewing gum showed no significant relationship with bowel sounds, first defecations, gas passage, and feeling bowel movements.
Conclusion: As the findings indicated, the use of chewing gum after CS was ineffective in the reduction of ileus. However, this practice was only capable of mitigating post-operative pain, and therefore can be used as an adjuvant technique for the management of post-operative pain.- انتشار مقاله: 22-09-1395
- نویسندگان: Reza Jafarzadeh Esfehani,Marzyeh Moosavi Yazd,Ali Jafarzadeh Rsfehani,Samira Foji,Batool Kamalimanesh
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Midwifery and Reproductive Health
- نوع مقاله: Journal Article
- کلمات کلیدی: Pregnancy,Cesarean section,Bicornuate Uterus
- چکیده:
- چکیده انگلیسی: Complete bicornuate uterus is a type of Mullerian duct deformity, resulting from abnormal duct fusion. Similar to other Mullerian anomalies, bicornuate uterus is associated with specific complications during possible pregnancies. While various studies have reported successful deliveries in a bicornuate uterus, it might be accompanied with various complications, ranging from preterm labor to more catastrophic outcomes such as uterine rupture. One of the current approaches to diagnose this abnormality is ultrasound monitoring. In the present report, we presented a 25-years-old multiparous women with a history of abortion. The patient was not diagnosed with a complete bicornuate uterus in her first unsuccessful pregnancy. However, she was suspected with a complete bicornuate uterus based on the findings of ultrasound in the present pregnancy. A successful cesarean section was performed on the subject in the 39th week of gestation. According to the results, successful delivery could be achieved in patients with bicornuate uterous. Considering factors such as recurrent miscarriage, suspicious findings, and unreliable results of ultrasound, other diagnostic evaluations, including magnetic resonance imaging and hysterosalpingography, are recommended.
- انتشار مقاله: 10-04-1395
- نویسندگان: Behnaz Souvizi,Reza Jafarzadeh Esfehani
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Midwifery and Reproductive Health
- نوع مقاله: Journal Article
- کلمات کلیدی: Pregnancy,Postpartum,Convulsion,Eclampsia,Posterior Reversible Ence-phalopathy Syndrome
- چکیده:
- چکیده انگلیسی: Posterior reversible encephalopathy syndrome (PRES) is associated with various clinical manifestations such as headache, blurred vision, confusion and tonic-clonic convulsion. Some of the predisposing factors for PRES include hypertensive encephalopathy, preeclampsia and eclampsia, lupus erythematosus, thrombotic thrombocytopenic purpura and long-term use of immunosuppressive drugs. This condition rarely occurs after normotensive and uneventful pregnancies. Several theories have been proposed on the etiology of PRES. For instance, endothelial injury and brain edema have been reported as possible causes of PRES. Although PRES is a temporary condition, proper and timely management of the disorder in the acute phase is critical for the prevention of permanent neurological complications. During pregnancy, PRES is normally accompanied with hypertension. In this paper, we present a rare case of PRES in a normotensive pregnancy in a 25-year-old parturient woman (Gravida 2, Ab 1). The patient unexpectedly manifested symptoms of tonic-clonic convulsion one hour after an uneventful vaginal delivery, which were successfully managed. According to our observations, PRES has various clinical manifestations with unexpected occurrence in some cases. Therefore, it is recommended that maternity centers be well-equipped with resuscitation tools, emergency drugs and expert staff so as to manage unforeseen PRES efficiently and prevent permanent maternal neurological complications and mortality.
- انتشار مقاله: 09-09-1394
- نویسندگان: Jila Agah,Reza Jafarzadeh Esfehani
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Midwifery and Reproductive Health
- نوع مقاله: Journal Article
- کلمات کلیدی: Sexual dysfunction,Orgasm,Women,Desire
- چکیده:
- چکیده انگلیسی: Background: Female sexual function (FSD) is a multifactorial phenomenon. Sexual function is influenced by different personal and environmental factors. This study aimed to evaluate FSD and its contributing factors using female sexual function index (FSFI).
Methods:This descriptive cross-sectional study was conducted on 264 women referring to 11 health centers of Sabzevar, Iran during October 2012 to January 2013 using a convenience sampling. Data were collected using a validated Persian version of FSFI containing six domains of sexual desire, lubrication, sexual arousal, sexual satisfaction, orgasm and sexual pain as well as demographic questionnaire. Results: The mean age of women enrolled in this study was 32.2±10.27 years . Considering the cut-off point of sexual dysfunction at 28, 62.1% of the study population had FSD. Highest rate of FSD was estimated at 49.2%, Age was associated with a significant decline in total scores of FSFI (P=0.042). Moreover, a significant correlation was observed between duration of marriage and total scores of FSFI (p <0.001).
Conclusion: According to the results, sexual desire was the most frequent contributing factor among FSD domains, and the majority of women ageing 21-26 years had at least one of the risk factors of FSD. In addition, our findings indicated that despite conventional beliefs, issues such as educational level has no significant effect on FSD in young women.- انتشار مقاله: 10-09-1394
- نویسندگان: Reza Jafarzadeh Esfehani,Nasrin Fazel,Sareh Dashti,Sedigheh Moshkani,Faezeh Haghighi Hasanabad,Samira Foji,Batool Kamalimanesh
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Midwifery and Reproductive Health
- نوع مقاله: Journal Article
- کلمات کلیدی: Ovary,Serous Cystadenoma,Ovarian neoplasm
- چکیده:
- چکیده انگلیسی: While ovarian masses are common findings in gynecology, unusually huge masses are quite rare. However, such cases can still be found today. Mismanagement of common complaints in patients can be a leading cause of facing such findings. Herein, we introduce a case of a giant ovarian cyst, which was mismanaged in a young virgin female patient. The patient had received gastrointestinal medications for months before being admitted to our clinic, given the bloating sensation and lack of any gynecologic problems. Ultrasonography disclosed a giant cyst, probably related to the ovary, originating from the pelvis and extending toward the diaphragm. After a successful surgery, the ovarian cyst, measuring 40 centimeters and weighing 8 kilograms, was removed. Pathology report revealed serous cystadenoma. Existence of such cases can be an alarming sign for physicians to manage prevalent complaints more seriously, particularly those non-responsive to treatment.
- انتشار مقاله: 15-09-1393
- نویسندگان: Jila Agah,Reza Jafarzadeh Esfehani,Batool Kamalimanesh,Mojtaba Fattahi Abdizadeh,Amir Reza Jalilian
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Otorhinolaryngology
- نوع مقاله: Journal Article
- کلمات کلیدی: genetic variant,Hearing loss,Gap Junction Protein Beta 2
- چکیده:
- چکیده انگلیسی: Introduction:
Hearing impairment is a complex medical disorder whichhas genetic and non-genetic causes. Gap Junction Protein Beta 2 (GJB2) gene variant is a well-known disease-causing gene among patients with hearing impairment. The frequencies of genetic variants in the GJB2 gene are different in each population. This study aimed to discuss the GJB2 gene status in an Iranian population with hearing impairment who referred for prenatal testing.
Materials and Methods:
This cross-sectional study was conducted in a genetic laboratory affiliated with Mashhad Jahad Daneshgahi, Mashhad, Iran. A total number of 21 bilateral hearing impaired patients were enrolled in this study. The exons for target GJB2 gene were amplified by polymerase chain reaction after the confirmation of the hearing impairment and the exclusion of the acquired causes of hearing loss.
Results:
The c.35delG and c.79G>A variants were the first and second most common variants in the study population, respectively. The mean age of the patients was 27.5 (8.7) years and 12 cases were male. There was no significant association between hearing impairment degree and age and heterozygosity status (P=0.376 and P=.074 respectively).
Conclusion:
The c.35delG and c.79G>A variants were determined as the first and second most common variants in the GJB2 gene, respectively. The mean age of 26 years in this study population indicates the late referral for the evaluation of the hearing difficulty. Furthermore, it highlights the further need to encourage families with a history of hearing impairment to engage in genetic counseling.- انتشار مقاله: 08-03-1397
- نویسندگان: Samane Vojdani,Reza Jafarzadeh Esfehani,Vahid Iranmanesh,Hafezeh Davari,Nasim Amini,Mohammad Ehsan Jaripour,Peyman Zargari,Mahtab Dastpak,Ariane Sadrnabavi
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Neonatology
- نوع مقاله: Journal Article
- کلمات کلیدی: Prevalence,Stillbirth,Neonatal Mortality,Perinatal Mortality
- چکیده:
- چکیده انگلیسی: Background: Perinatal mortality rate is an important indicator of community health status. This study aimed to evaluate perinatal mortality and its determinants in Mobini Hospital of Sabzevar, Iran. Methods: This descriptive, cross-sectional study was performed within a two-year (2011-2012) period at Mobini Hospital of Sabzevar. Our study population included all the cases of stillbirth and live birth after the 22nd week of gestation to full term, died within the first week after delivery. The data including maternal and neonatal/fetal age, parity, mode of delivery, history of stillbirth, gestational age, reason of death, gender, and weight of the fetus or newborn were obtained from patient records as well as interviews with the mothers and treating physicians. To analyze the data, independent sample t-test, and Chi T square/Fisher’s exact test were run using SPSS, version 11.5. Results:Perinatal mortality and stillbirth rates were 16.6 and 9.1 per 1000 births, respectively, while the rate of early neonatal mortality was 7.4 per 1000 live births. The most common reasons for neonatal death were pre-term labor and sepsis, while the most common reason for stillbirth was unknown etiology. There was a significant difference between stillbirth and early neonatal death in term of gestational age (P<0.001). Conclusion: According to our results, perinatal mortality rate in our region was not high compared to other regions of the country, although it was higher than that of European countries. We found that premature labor was the cardinal cause of neonatal mortality, which can be prevented by careful perinatal care and improving hospital equipment, especially those of neonatal intensive care units.
- انتشار مقاله: 01-01-1395
- نویسندگان: Fereshteh Ghorat,Reza Ghafarzadeh,Reza Jafarzadeh Esfehani
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: Karyotype,follicle-stimulating hormone,Turner’s syndrome
- چکیده:
- چکیده انگلیسی: Background
Abnormal pubertal development and fertility are among the frequent complications in Turner’s syndrome. Although elevated level of gonadotropins in Turner’s syndrome patients is well documented, the possible correlation with the karyotype findings and anthropometric features of patients is not clearly addressed. The present report aimed to evaluate the relation between the follicle-stimulating hormone (FSH) serum level and cytogenetic findings in Iranian Turner’s syndrome patients.
Materials and Methods: Abnormal pubertal development and fertility are among the frequent complications in Turner’s syndrome. Although elevated level of gonadotropins in Turner’s syndrome patients is well documented, the possible correlation with the karyotype findings and anthropometric features of patients is not clearly addressed. The present report aimed to evaluate the relation between the follicle-stimulating hormone (FSH) serum level and cytogenetic findings in Iranian Turner’s syndrome patients.
Results: The mean age of the Turner’s syndrome patients was 9.78 years and most of the patients were mosaic for Turner syndrome (54.3%). Although the FSH level increased, there was not any significant different between the FSH level in the initial evaluation and the second evaluation within the entire study population (P=0.605). Among those who were mosaic for Turner’s syndrome and those with 45,XO karyotype, the FSH level increased during the follow up (P=0.476, and P=0.357, respectively).
Conclusion
The present study demonstrated that although Turner’s syndrome patients face abnormal FSH levels, there is not any significant relation between the cytogenetic findings as well as anthropometric characteristics including height, weight and BMI with the serum FSH levels.- انتشار مقاله: 28-09-1399
- نویسندگان: Fatemeh Zarei,Moein Mobini,Reza Jafarzadeh Esfehani,Maryam Khalesi,Rahim Vakili
- مشاهده