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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: International Journal of Molecular and Clinical Microbiology
- نوع مقاله: Journal Article
- کلمات کلیدی: Antibiotic resistance,Damghan,Dysentery,Shigella,Baradaran Rezaei
- چکیده:
- چکیده انگلیسی: Shigella is a major cause of dysentery across the world. Appropriate antibiotic treatment of shigellosis depends on resistance patterns. The present study was conducted to identify Shigella species and their antibiotic resistance patterns among dysenteric patients in Rezaei Hospital of Damghan. Isolation of Shigella species was conducted by specific culture medium and biochemical tests. The Shigella species were determined by specific antiserum with agglutination on slide. Then, susceptibility to different antibiotics, i. e. nalidixic acid, ciprofloxacin, ampicillin, tetracycline, co-trimoxazole and ceftriaxone, was tested. The antibiotic susceptibility tests were carried out using the Kirby-Bauer standard method on Mueller-Hinton agar.In this study, 29 Shigella species were found in 91 stool samples of the patients. Determination of Shigella spp. by specific antiserum showed S. flexneri (group B) in 13 cases, S. dysenteriae (group A) in 10 cases, and S. sonnei (group D) in 6 cases, while no case of S. boydii (group C) was found. The antibiotic resistance tests indicated that resistance to co-trimoxazole, tetracycline, ampicillin, nalidixic acid, ciprofloxacin and ceftriaxone was 75.8%, 65.5%, 55.1%, 6.8%, 3.4% and 0% respectively. According to lower resistance to ciprofloxacin and ceftriaxone, it seems that the fluoroquinolone antibiotic, as the first choice, and the third-generation cephalosporin, as the second choice, were suitable for treatment of shigellosis, but regarding the multidrug-resistance likelihood and antibiotic resistance patterns variation in Shigella strains, it is recommended to perform the organism susceptibility test to the antibiotic before treatment.
- انتشار مقاله: 26-07-1395
- نویسندگان: Mansoor Khaledi,Reza Heidari Soureshjani,Hanieh Asaadi,Abdollah Ardebili,Sajjad Yazdansetad
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: anxiety,children,Mindfulness,self-efficacy,Mother,Happiness
- چکیده:
- چکیده انگلیسی:
Background
Children's anxiety disorders not only lead to problems related to themselves but also cause problems and confusion in the family. The present study aimed to investigate the effectiveness of happiness and mindfulness training in promoting the parental self-efficacy in mothers of anxious preschool children.
Materials and Methods: This is an experimental research in terms of method with a pretest-posttest-follow-up design and a control group. The study population included all mothers of preschool anxious children in Shahrekord, Iran in 2018. Using the multistage sampling method, a sample of 45 individuals were selected and assigned randomly to a control and two experimental groups (n=15 per group). The research tools included Spence Children's Anxiety Scale (SCAS), and Parenting Self-Agency Measure (PSAM). Mindfulness (eight 90-minute sessions), and happiness (ten 90-minute sessions) training were conducted on the experimental groups. The control group did not receive any intervention. SPSS (version 24) was further used for data analysis.
Results: The mean age of the participants in the mindfulness training, happiness training and control groups were 34.36±2.59, 36.08±2.63 and 34.20±2.29, respectively. The results indicated that the mean of post-test and follow-up scores were significantly different in the experimental and control groups. Furthermore, the happiness training for the mothers of anxious children was effective in their parenting self-efficacy (P=0.000); and a one-month follow-up in the experimental group indicated that the therapeutic intervention could maintain its intervention effect over time (P=0.000).
Conclusion
Based on the results, mindfulness and happiness training methods could have lasting effects on the parent-child relationship and change the anxious relationship between parent and child, leading to parental self-efficacy.
- انتشار مقاله: 16-02-1399
- نویسندگان: Arjang Fereydooni,Alireza Heidari,Zahra Eftekhar Saadi,Parvin Ehteshamzadeh,Reza Pasha
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Psychology (IPA)
- نوع مقاله: Journal Article
- کلمات کلیدی: anxiety,depression,Breast cancer,relaxation,Mental Imagery,Hopefulness
- چکیده: The aim of this research was to determine the effectiveness of mental imagery and relaxation on the rate of anxiety, depression and hopefulness in women suffering from breast cancer in Ahvaz Golestan Hospital. The subjects were 40 women suffering from breast cancer. The patients were selected through random sampling and were divided into two groups of 20 persons. One group was taken as the experimental and the other as the control group. The measurement instruments were Cattel Anxiety Questionnaire (CAQ), Beck Depression Inventory (BDI), and Miller Hopefulness scale (MHS), and a pretest was administered to both groups. Then, the experimental group underwent training ways and techniques of mental imagery and relaxation for one month (4 weeks), and 4 sessions per week for 45 minutes in the moarings and afternoons. After applying intervention, the two groups were tested again. For the analysis of the data the indices of mean, standard deviation and the multivariate analysis of variance (MANOVA) were used. The results indicated that mental imagery and relaxation were effective mitigators of anxiety and depression, and enhancers of hopefulness in women suffering from breast cancer
- چکیده انگلیسی: The aim of this research was to determine the effectiveness of mental imagery and relaxation on the rate of anxiety, depression and hopefulness in women suffering from breast cancer in Ahvaz Golestan Hospital. The subjects were 40 women suffering from breast cancer. The patients were selected through random sampling and were divided into two groups of 20 persons. One group was taken as the experimental and the other as the control group. The measurement instruments were Cattel Anxiety Questionnaire (CAQ), Beck Depression Inventory (BDI), and Miller Hopefulness scale (MHS), and a pretest was administered to both groups. Then, the experimental group underwent training ways and techniques of mental imagery and relaxation for one month (4 weeks), and 4 sessions per week for 45 minutes in the moarings and afternoons. After applying intervention, the two groups were tested again. For the analysis of the data the indices of mean, standard deviation and the multivariate analysis of variance (MANOVA) were used. The results indicated that mental imagery and relaxation were effective mitigators of anxiety and depression, and enhancers of hopefulness in women suffering from breast cancer
- انتشار مقاله: 27-02-1394
- نویسندگان: Ali Reza Heidari,Parviz Asgari,Heshmatollah Darvishi
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of School Health
- نوع مقاله: Journal Article
- کلمات کلیدی: Resilience,Students,Education,Spiritual intelligence,responsibility
- چکیده:
- چکیده انگلیسی: Background: Spiritual intelligence is one of the important and influential variables in many psychological characteristics including resilience and responsibility. Objectives: Based thereon, the present study was conducted with the objective of determining the effectiveness of spiritual intelligence training in responsibility and resilience of secondary high school students in the city of Baghmalek.
Methods: The present study was a semi-experimental study with pretest-posttest design and experimental/control groups. The research population included all secondary high school students from Baghmalek city during 2017 - 2018. Finally, 60 students were selected by the multistage cluster sampling method and randomly assigned to experimental and control groups. Data collection was done using the Connor-Davidson resilience scale (CD-RISC) and Kordlou’s responsibility questionnaire. The experimental group participated in eight 90-min sessions for spiritual intelligence instruction while the control group was placed in a waiting list and did not receive any instructions. After the termination of the sessions, both of the groups were subjected to posttest.
Results: The results indicated that there was a linear significant relationship between the pretest and posttest scores of resilience (F = 56.32, P < 0.001) and the pretest and posttest scores of responsibility (F = 12.98, P = 0.004) in the experimental and control groups. The results of univariate analysis for resilience (F = 15.55, P < 0.001) and responsibility (F = 7.14, P = 0.016) as dependent variables were found significant. Thus, spiritual intelligence instruction increased resilience and responsibility in students.
Conclusions: Spiritual intelligence training could be an appropriate interventional method for enhancing the students’ responsibility and resilience considering the society’s need for committed and flexible students who can resist problems and challenges.- انتشار مقاله: 02-09-1397
- نویسندگان: Ali Javadi Nejad,Alireza Heidari,Farah Naderi,Saeed Bakhtiyar Pour,Fariba Haffezi
- مشاهده
- جایگاه : پژوهشی
- مجله: Geopersia
- نوع مقاله: Journal Article
- کلمات کلیدی: Pillow lava,radiolarian biostratigraphy,Early Middle Jurassic,Central Iran,Ghaleh-Rigi
- چکیده:
- چکیده انگلیسی: The Ghaleh-Rigi complex is located in northern margin of the Sanandaj–Sirjan Zone (western Iran) and the southern part of the Central Iran Micro-continent block. The study area is covered by pillow and massive lava flows associated with micro gabbro and pelagic sediments including mudstone and radiolarian ribbon chert. Geochemical analysis indicates similar mantle source for magmatic rocks. These rocks show tholeiitic affinity with depletion in high-field strength elements (HFSEs) and light rare-earth elements (LREEs). They also show enrichment in large-ion lithophile elements (LILEs) in primitive mantle normalized multi-element diagrams. All samples show variable depletion in Th followed by depletion of HFSE and trace element concentrations and negative Nb anomaly (Th/Nb=0.23-035), which is a typical characteristic from magmas related to subduction zone. In addition, ratio of Y/Nb against Zr/Nb and Ce/Y against Zr/Nb and also REE flat patterns are similar to N-MORB-like source. These features suggest generation of magma in the back-arc basin. According to geochemical and petrogenesis studies, these rocks shows around 10% partial melting of a mixed spinel–garnet-bearing source composed of 50% PM and 50% MORB source. Based on bio-chronological investigation, the radiolarian cherts associated with volcanic rocks show Early Bajocian to Berriasian; Callovian- Valanginian; and Oxfordian- Valanginian ages.
- انتشار مقاله: 28-12-1397
- نویسندگان: Saeed Saadat,Ahmad Mazaheri,Mohamad Reza Heidarian,Hojat Jahangiri,Mohammad Foudazi,Seyed Jafar Omrani
- مشاهده
- جایگاه : پژوهشی
- مجله: Environmental Energy and Economic Research
- نوع مقاله: Journal Article
- کلمات کلیدی: reliability,Bayes networks,Fault Tree Analysis,Automatic systems,Fire extinguishing system
- چکیده:
- چکیده انگلیسی: In this study, the application of Bayes networks and fault tree analysis in reliability estimation have been investigated. Fault tree analysis is one of the most widely used methods for estimating reliability. In recent years, a method called "Bayes Network" has been used, which is a dynamic method, and information about the probable failure of the system components will be updated according to the components data. In other words, the Bayes network is generally distributed with primary values and relations between variables. In this research, the reliability of the automatic Environmental detection and fire extinguisher system by water sprinkler system has been estimated by FTA and BAYES NETWORKS, also their comparison has been investigated. The probabilistic calculation and the graphical drawing required for this research has been completed by MATLAB and MICROSOFT BAYES NETWORK software. Finally, the reliability of an automatic water sprinkler system was calculated 0.93 by FTA. By updating the probability of failure and success, this value was changed to 0.89. The reason for the difference can be interpreted by taking into account the third state of the system, i.e., functioning with lower efficiency. The lowest level of reliability relates to a diesel generator that acts as a standby member in the event of a power failure. At the end, suggestions for improving the reliability of the automatic fire sprinkler system provided.
- انتشار مقاله: 18-09-1397
- نویسندگان: Saeed Givehchi,Alireza Heidari
- مشاهده
- جایگاه : پژوهشی
- مجله: Avicenna Journal of Phytomedicine
- نوع مقاله: Journal Article
- کلمات کلیدی: Insulin,Diabetes Mellitus,glibenclamide,Capparis spinosa
- چکیده:
- چکیده انگلیسی: Objective: Diabetes mellitus is the most common metabolic disorders with severe impact on quality of life. Reducing serum glucose levels and normalization of serum lipid is of great clinical importance for treating diabetes. To our knowledge, there are not any evidences about the anti-diabetic action of capparis spinosa root. In the present study the effects of the C. spinosa root extract on diabetic metabolic disorders have been studied in experimental diabetes.
Materials and Methods: Rats were divided into six groups: normal control (NC), diabetic control (DC), diabetic rats receiving 0.2, 0.4 g/kg of plant extract or 0.6 mg/kg glibenclamide (groups D0.2, D0.4 or DG respectively). A normal group of rats was also designed to receive 0.2 g/kg of plant extract (N0.2). Rats were rendered diabetic (streptozotocin 60 mg/kg, i.p.) and treated with 0.2, 0.4 g/ kg of plant extract or glibenclamide for four weeks. At the end of the experiment, blood was drawn through heart puncture under deep anesthesia. Weight was measured weekly, glucose levels were measured at the first and fourth week and lipid profiles, insulin and liver enzymes at the end of the study.
Results: Glucose levels significantly decreased after treating with plant extract (p=0.003). However, insulin levels did not increase in any treating groups. Plant extract could significantly raise HDL and reduce levels of LDL and liver enzymes (ALT and ALP).
Conclusion: These results showed that C. spinosa rootextract could improve diabetic related metabolic derangement such as hyperglycemia, dyslipidemia, and elevated liver markers in an insulin-independent manner.- انتشار مقاله: 26-07-1393
- نویسندگان: Mostafa Kazemian Mansur Abad,Mohammad Reza Haeri,Mansoor Ebrahimi,Reza Heidari
- مشاهده
- جایگاه : پژوهشی
- مجله: Avicenna Journal of Phytomedicine
- نوع مقاله: Journal Article
- کلمات کلیدی: Rat,Liver,Epilepsy,Lamotrigine,Zingiber officinale
- چکیده:
- چکیده انگلیسی: Objective: Lamotrigine is an antiepileptic drug, widely used in the treatment of epilepsy; long-term use of this drug can cause hepatotoxicity. Zingiber officinale Roscoe (ginger) possesses antioxidant properties. In present research, the effect ofhydroalcoholic extract of ginger (HEG) on the liver of lamotrigine-treated epileptic rats was investigated
Material and Methods: Forty-eight female Wistar rats were selected and allocated to 8 groups of 6 each. Group 1: Negative controls were treated with normal saline. Group 2: Positive controls were treated with lamotrigine (LTG) (10 mg/kg) daily by gavages for 4 consecutive weeks. Epilepsy was induced in treatment groups by i.p. injection of pentylenetetrazol (PTZ) (40 mg/kg). Group 3: Epileptic group received normal saline (10 ml/kg). Group 4: Epileptic group was treated with LTG (10 mg/kg). Groups 5 and 6: Epileptic groups received HEG (50 and 100 mg/kg). Groups 7 and 8: Epileptic groups received LTG and HEG (50 and 100 mg/kg). At the end of 28 days, blood samples were drawn and their livers were processed for light microscopy.
Results: The mean values of TG, CHOL, AST, and ALT activity significantly rose (p<0.01) in groups 2, 3, and 4, while in rats treated with HEG (groups 5, 6, 7, and 8), the levels of liver enzymes significantly decreased (p<0.05) compared with epileptic group treated with lamotrigine (group 4). Histopathological changes of liver samples were comparable with respective control.
Conclusion: These results suggest that hydroalcoholic extract of ginger improves liver function in lamotrigine-induced hepatotoxicity.- انتشار مقاله: 17-04-1392
- نویسندگان: Ameneh Poorrostami,Farah Farokhi Farokhi,Reza Heidari
- مشاهده
- جایگاه : پژوهشی
- مجله: Avicenna Journal of Phytomedicine
- نوع مقاله: Journal Article
- کلمات کلیدی: Mice,Sperm,Oxymetholone,Royal jelly
- چکیده:
- چکیده انگلیسی: Objectives: The aim of the present study was to evaluate protective effect of royal jelly on sperm parameters, testosterone level, and malondialdehyde (MDA) production in mice.
Materials and Methods: Thirty-two adult male NMRI mice weighing 30±2 g were used. All the animals were divided into 4 groups. Control group: received saline 0.1 ml/mouse/day orally for 30 days. Royal Jelly group (RJ): received royal jelly at dose of 100 mg/kg daily for 30 days orally. Oxymetholone group: the received Oxymetholone (OX) at dose of 5 mg/kg daily for 30 days orally. Royal Jelly+Oxymetholone group: received royal jelly at dose of 100 mg/kg/day orally concomitant with OX administration.
Sperm count, sperm motility, viability, maturity, and DNA integrity were analyzed. Furthermore, serum testosterone and MDA concentrations were determined.
Results: In Oxymetholone group, sperm count, motility as well as testosterone concentration reduced significantly (p<0.05), while significant (p<0.05) increases in immature sperm, sperm with DNA damaged, and MDA concentration were announced in Oxymetholone group in comparison with control group and Royal Jelly+Oxymetholone group. RJ caused partially amelioration in all of the above- mentioned parameters in Royal Jelly+Oxymetholone group.
Conclusion: In conclusion, RJ may be used in combination with OX to improve OX-induced oxidative stress and male infertility.- انتشار مقاله: 09-12-1391
- نویسندگان: Ensieh Zahmatkesh,Gholamreza Najafi,Vahid Nejati,Reza Heidari
- مشاهده
- جایگاه : پژوهشی
- مجله: Avicenna Journal of Phytomedicine
- نوع مقاله: Journal Article
- کلمات کلیدی: Diabetes Mellitus,Streptozotocin,Berberis integerrima,Renal protective
- چکیده:
- چکیده انگلیسی: Objective: Barberry root extract contains various alkaloids that are considered as antioxidants. Beneficial effect of aqueous extract of Berberis integerrima root (AEBIR) was evaluated for renal function in diabetic rats induced by STZ.
Material and Methods: Diabetes was induced by i.p. injection of streptozotocin (65 mg/kg bw) to rats, after 15 h of fasting. Diabetic rats were randomly grouped and treateddaily with AEBIR and glibenclamide by gavage for 42 days. After 6 weeks of study, all the rats were sacrificed and some biochemical parameters of serum and urine were measured and their kidneys tissues were processed for light microscopy.
Results: Streptozotocin induced a significant rise in fasting blood glucose, serum creatinine, blood urea nitrogen, urine glucose, urine protein, urine albumin, and water intake and a significant decrease in body weight, serum protein, urine urea, and urine creatinine. There was a significant restoration of these parameters to near normal after administration of the AEBIR and also by glibenclamide (0.6 mg/kg bw). The activity of the extract at dose of 500 mg/kg in all parameters except blood glucose and urine glucose was more than that of the standard drug, glibenclamide (0.6 mg/kg, p.o.). Histopathological changes of kidney samples were comparable with respective control.
Conclusion: These results suggested that aqueous extract of Berberis Integerrima root improves renal dysfunction in streptozotocin-induced diabetic rats through controlling blood glucose and renal protective effects.- انتشار مقاله: 04-05-1391
- نویسندگان: Hossein Ashraf,Reza Heidari,Vahid Nejati,Minoo Ilkhanipoor
- مشاهده