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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Journal of Health Literacy
- نوع مقاله: Journal Article
- کلمات کلیدی: Quality of Life,effective factors,quality of mental life,quality of objective life
- چکیده:
- چکیده انگلیسی: Background and Objective: The quality-of-life index is like a graph that describes the situation of all people living in a region or country and includes economic, social, and human variables. The results of various studies have shown that quality of life can be affected by various individual, social and environmental factors. This study aims to summarize the results of research conducted in the country with a focus on factors affecting the quality of life in the general population of Iran.
Materials and Methods: This study was a systematic review based on reviewing relevant document. All articles that published in Iranian electronic databases (example Magiran, SID, and Noormags) were examined via keywords related to the quality of life and its effective factors in the general population. Studies that met the inclusion criteria were evaluated in all years.
Results: In this research, 46 studies were reviewed from 2008 to 2018. Based on the results of the studies, some contextual and social variables such as; age, level of education, occupation, income, social capital, marital status, housed hold Size, socio-economic status, and social participation of individuals introduced as factors related to the quality of life. Also, the quality of life in the women studied was not very high.
Conclusion: Since the results of studies confirm that the impact of various individual, environmental and social factors on the individual’s quality of life, the dynamism and continuous changes in the quality of life over time, and the different opinions of different scientific groups about the indicators affecting quality of life. It is suggested that more attention must be paid to research on this structure, individual and social components that affect individual’s quality of life.- انتشار مقاله: 04-09-1399
- نویسندگان: Asieh Namazi,Hassan Rafiey,Mirtaher Mousavi,Ameneh Setareh Forouzan,Gholamreza Ghaed Amini
- مشاهده
- جایگاه : پژوهشی
- مجله: Geopersia
- نوع مقاله: Journal Article
- کلمات کلیدی: sedimentary environment,Intrinsic Compression line,Strength Sensitivity,Stress Sensitivity
- چکیده:
- چکیده انگلیسی: This research was performed to determine the efficiency effect of sedimentary environment of Kerman City area on soil structure by
comparing natural and reconstituted consolidation curves. In this regard, four different criteria such as sensitivity strength, stress
sensitivity, Schmertman criteria and the result of the uniaxial compression test were used. The base of these criteria is to compare the
results of natural and undisturbed soil consolidation tests. The position of undrained shear strength of Kerman City soils in Iv-Su space
was located on the left side of the intrinsic strength line and this confirms that the stress sensitivity of soils is less than the unit.
Therefore, the soils in the city subzone are mostly over consolidated, and cementation and chemical bonds have not developed. The
swelling sensitivity of fine grained soils based on Schmertman criteria are often less than 2 or slightly larger than 2.5 indicating that the
soils of Kerman City subzones have underdeveloped swelling sensitivity due to poor cementation.- انتشار مقاله: 13-12-1392
- نویسندگان: Mohammad Reza Aminizadeh Bazanjani,Iman Aghamolaie,Golamreza Lashkaripour,Mohammad Ghafoori
- مشاهده
- جایگاه : پژوهشی
- مجله: Geotechnical Geology
- نوع مقاله: Journal Article
- کلمات کلیدی: Artificial Neural networks (AAN),Feedforward Backpropagation,Multivariate Linear Regression (MLR),Asmari Formation,Uniaxial Compressive Strength (USC),Modulus of Elasticity (E),Cohesive Strength (C),internal friction angle
- چکیده:
- چکیده انگلیسی: A number of common laboratory rock mechanics tests are carried out in all geotechnical projects such as dams, to determine parameters such as porosity, density, water absorption, sonic velocity, Brazilian tensile strength, uniaxial compressive strength, and triaxial compressive strength. In this paper, data obtained from two dams in Asmari Formation including Khersan 1 and Karun 4 - both located in Chahar-Mahal Va Bakhtiari Province, Iran - have been subjected to a series of statistical analyses. Then, using Multivariate Linear Regression (MLR) and Artificial Neural Networks values of UCS, E, C, and φ were predicted using the input parameters including depth, compression ultrasonic velocity, porosity, density, and Brazilian tensile strength. The designed ANN in this research was a feedforward backpropagation network which is powerful tool to solve prediction problems. Designed network had two hidden layer (hidden layer 1: 18 neurons and hidden layer 2: 20 neurons). Via comparing designed MLR and ANN models, it was revealed that ANNs (R2 UCS= 0.91, R2 = 0.87, R2 =0.78, R2 EC phi = 0.61) are more efficient than MLR models (R2 UCS= 0.69, R = 0.69, R = 0.66, and R2 22 EC phi = 0.50) in predicting strength and shear parameters of the intact rock. Also, to enhance the credibility of this study, some extra tests were carried out to evaluate the efficiency of network designed for prediction of strength parameters. The results obtained from this network were as: R2 UCS= 0.85, R2E = 0.81.
- انتشار مقاله: 05-06-1399
- نویسندگان: Mahdi Razifard,Mashallah Khamechiyan,Mohammad Reza Amin‐Naseri
- مشاهده
- جایگاه : پژوهشی
- مجله: VETERINARY RESEARCH FORUM
- نوع مقاله: Journal Article
- کلمات کلیدی: Proliferation,Mesenchymal Stem Cells,Bio,Mouse,Cartilage differentiation
- چکیده:
- چکیده انگلیسی: In vitro expansion of mesenchymal stem cell (MSCs) into large number is necessary for their application in cell-based treatment of articular cartilage defects. On the other hand, some studies have indicated that BIO (6-Bromoindirubin-3-Oxime) possesses mitogenic effects on cell culture. The objective of the present study was to examine the effect of BIO on in vitro expansion and chondrogenic differentiation of mouse marrow-derived MSCs. The culture was established using bone marrow tissue obtained from 10 NMRI mice. MSC nature of the isolated cells was verified according to the minimal criteria proposed for MSC. Passaged-3 cells were seeded in 24-well culture plates and treated by 0.05, 0.01, 0.1, 1.0 and 1.5 µM BIO for seven days. The culture without BIO was taken as the control. At the end of cultivation period, the cultures were examined for viable cell number which was then used to calculate population doubling time (PDT). The BIO with higher proliferation-promoting effect was investigated for its chondrogenic effect on MSC culture. There was significantly more viable cells at the cultures treated by 0.1 µM BIO. At this culture the cells tended to double their population in rapid rate (each 43.07 hr) than the cells treated with the other BIO concentrations (p < 0.05). Interestingly treatment of MSC chondrogenic culture with 0.1 µM BIO led to the up-regulation of cartilage specific genes including aggrecan, collagen II and sox9. In conclusion BIO at 0.1 µM could enhance mouse MSC in vitro proliferation as well as their chondrogenic differentiation. These findings would be of great importance for the field of regenerative medicine.
- انتشار مقاله: 25-03-1392
- نویسندگان: Mohamadreza Baghaban Eslaminejad,Nasrin Fallah
- مشاهده
- جایگاه : پژوهشی
- مجله: VETERINARY RESEARCH FORUM
- نوع مقاله: Journal Article
- کلمات کلیدی: Proliferation,Culture,Mesenchymal Stem Cells,Differentiation,Rabbit ear blastema
- چکیده:
- چکیده انگلیسی: Rabbits have the capacity to regenerate holes in their ears by forming a blastema, a tissue that is made up of a group of undifferentiated cells. The purpose of the present study was to isolate and characterize blastema progenitor cells and compare them with marrow mesenchymal stem cells (MSCs). Five New Zealand white male rabbits were used in the present study. A 2-mm hole was created in the animal ears. After 4 days, the blastema ring formed in the periphery of the hole was removed and cultivated. The cells were expanded through several subcultures and compared with the MSCs derived from the marrow of same animal in terms of in vitro differentiation capacity, growth kinetics and culture requirements for optimal proliferation. The primary cultures from both cells tended to be heterogeneous. Fibroblastic cells became progressively dominant with advancing passages. Similar to MSCs blastema passaged-3 cells succeeded to differentiate into bone, cartilage and adipose cell lineages. Even lineage specific genes tended to express in higher level in blastema cells compared to MSCs (p < 0.05). Moreover blastema cells appeared more proliferative; producing more colonies (p < 0.05). While blastema cells showed extensive proliferation in 15% fetal bovine serum (FBS), MSCs displayed higher expansion rate at 10% FBS. In conclusion, blastema from rabbit ear contains a population of fibroblastic cells much similar in characteristic to bone marrow mesenchymal stem cells. However, the two cells were different in the level of lineage-specific gene expression, the growth curve characteristics and the culture requirements.
- انتشار مقاله: 08-10-1391
- نویسندگان: Mohamadreza Baghaban Eslaminejad,Sima Bordbar
- مشاهده
- جایگاه : پژوهشی
- مجله: Research Journal of Pharmacognosy
- نوع مقاله: Journal Article
- کلمات کلیدی: plants,Amino acids,minerals,Nutritive value ,medicinal,Eryngium
- چکیده:
- چکیده انگلیسی: Background and objectives: Eryngium caeruleum M.Bieb. (Syn. Eryngium caucasicum Trautv.)belongs to Apiaceae family. It is found abundantly in northern provinces of Iran as an edible plant. Hundreds of years ago, Eryngium genus was known as a medicinal herb in Persian medicine books which was named “Qaracaane” and the plant’s roots were used in traditional medicine. The aim of this study was to evaluate the nutritional parameters in roots, spring and autumn leaves of E. caucasicum for the first time. Methods: The parameters including proximate composition (protein, carbohydrate, fat, fiber, ash, moisture and calorie) were measured by the standard methods of the AOAC, mineral contents (iron, zinc, copper and manganese) were measured by atomic absorption and amino acid contents was measured by RP-HPLC. Results: Regarding the results, it was found that the autumn leaves showed the highest amount of fiber, protein, moisture, zinc, copper and manganese. Also, spring leaves contained the highest levels of calorie, while the roots showed much more ash, carbohydrate and iron content. In terms of amino acids contents, threonine was the dominant among the rest of essential amino acids in all investigated parts of E. caeruleum. The results showed that both the aerial parts and the roots of Eryngium caeruleum could be good sources of nutritional ingredients. Conclusion: According to the obtained results it can be concluded that E. caeruleum has the capacity for prospective production of new natural medicinal supplements in order to improve body health and prevent or treat diseases.
- انتشار مقاله: 20-09-1398
- نویسندگان: Masoumeh Ghajarieh Sepanlou,Fatemeh Salami,Mehran Mirabzadeh Ardakani,Seyedeh Nargess Sadati Lamardi,Sima Sadrai,Gholam-Reza Amin,Naficeh Sadeghi,Mannan Hajimahmoodi*
- مشاهده
- جایگاه : پژوهشی
- مجله: Research Journal of Pharmacognosy
- نوع مقاله: Journal Article
- کلمات کلیدی: Acute,Wistar rats,toxicity test,Arctium lappa L,subchronic
- چکیده:
- چکیده انگلیسی: Background and objectives: Arctium lappa belonging to the Compositae (Asteraceae) family has been used as a medicinal and nutritional supplement in the world. The fruits, leaves and roots of the plant are well-known for their pharmaceutical effects. Toxicity of the fruit’s extract in female rats was investigated in the present study. Methods: To assess the toxicity profile of Arctium lappa fruit extract (ALFE), it was administered to rats by gavage in acute and repeated models. The animals were divided into two groups: control and test groups. In the acute toxicity model, 1000 and 5000 mg/kg ALFE were administered to the animals. Toxic symptoms, body weight, death and abnormal behaviors were observed for 14 days. In the repeated toxicity model, ALFE (300 mg/kg) was daily administered for 4 weeks. Biochemical and histopathological changes were assessed and compared with the control group. Statistical significance was determined by one-way analyses of variance, followed by the Tukey test using GraphPad Prism 6. Results: No mortality was noticed in the acute test; therefore, the oral LD50 value determined in the female rats was greater than 5000 mg/kg. In the repeated test, the animals received ALFE (300 mg/kg) and no mortality was observed. The hematology and serum chemistry parameters showed no statistically significant changes. The histopathological studies revealed evidences of microscopic lesions in two main organs lungs and small intestine. Conclusion: The results indicated that the oral acute toxicity of ALFE in the rats was of a low order with LD50 being more than 5000 mg/kg. Moreover, they revealed slight tissue damage to several organs when sub-chronically administered at a dose of 300 mg/kg.
- انتشار مقاله: 05-03-1397
- نویسندگان: Maedeh Yaghoubi,Zahra Mousavi*,Tayebeh Rastegar,Gholamreza Amin
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Nanoanalysis
- نوع مقاله: Journal Article
- کلمات کلیدی: Avena sativa L,Green Synthesis of Silver Nanoparticles,Aqueous and Hydroalcoholic Extracts
- چکیده:
- چکیده انگلیسی: Nanoparticles bio production, considering their performance in medicine and biological
science, is increasing; also, raising awareness of green chemistry and bioprocesses has
encouraged the use of environmentally friendly methods for the production of non-toxic
nanomaterials.. Also uses of plant extracts are found to be more advantageous over chemical,
physical and microbial (bacterial, fungal, algal) methods for silver nanoparticles (AgNPs)
synthesis. The objectives of this study were the production of silver nanoparticles using aqueous and
hydroalcoholic extracts of Avena sativa L. an investigation of the effect of extracts on the
synthesis of nanoparticles. The morphology and size of the nanoparticles were determined
using Scanning Electron Microscope (SEM) and UV-Vis spectroscopy. SEM images showed that
the synthesized nanoparticles were mainly spherical and round shaped. The results indicated
that synthesized nanoparticles using an aqueous extract were better than the synthesized
nanoparticles using hydro-alcoholic extract in shape and size.
Synthesize silver nanoparticles using Avena sativa L. Extract provides environmentally friendly
option as compared to currently available chemical/ physical methods.- انتشار مقاله: 28-01-1396
- نویسندگان: Nooshin Amini,Gholamreza Amin,Zahra Jafari Azar
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Pharmaceutical and Health Sciences (JPHS)
- نوع مقاله: Journal Article
- کلمات کلیدی: Reproductive,Fertility index ,Spermatozoa,phytoestrogen,Vitex
- چکیده:
- چکیده انگلیسی: Background: Phytoestrogens are some plant compounds with estrogenic biological effects which are found in many nutritional sources as soybean, flaxseed, and sesame. Vitex agnus-castus, also called Vitex, owns phytoestrogen properties. Studies have shown that phytoestrogens have different impacts on the gestation process and reproduction indices. Objective: The present study was aimed to investigate the effects of Vitex extract on the gestation indices in the male rat as well as studying its histological properties in the rat testicles. Materials and Methods: The hydro-alcoholic extract of Vitex (in three doses of 165, 265 and 365 mg/kg), vehicle (normal saline) and the hydro-alcoholic powder of soybean (120 mg/kg) were respectively given to understudy, vehicle and positive control groups for 49 days. After weighing the rats in the 1st and 49th days, the blood samples of all groups were taken and tested for estradiol levels, testosterones, FSH and LH. Moreover, such reproductive indices as sperm count, sperm motion, and prostate and testicle weight were studied and samples were collected for histological studies. Results: Prescription of the hydro-alcoholic extract of Vitex (in three doses of 165, 265 and 365 mg/kg) did not change the rat’s weight, significantly (P-value= 0.06). Hormonal studies reduced the progesterone, LH, and FSH compared to the vehicle group, significantly (P-value<0.05). In addition, the amount of estradiol was significantly more than the vehicle group and the most effect was observed at a dose of 365 mg/kg (P-value=0.02). Histological studies showed a reduction in existing spermatozoa in the seminiferous ducts. Conclusions: This study had shown that the Vitex extract had inhibiting effects on the gestation indices in male rat and due to its destructive effects on the testicle tissues, more studies were required.
- انتشار مقاله: 19-10-1395
- نویسندگان: Fereshteh Ramezanloo,Parvaneh Najafizadeh,Tahereh Naji,Gholamreza Amin,Zahra Mousavi,Gelareh Vahabzadeh
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Pharmaceutical and Health Sciences (JPHS)
- نوع مقاله: Journal Article
- کلمات کلیدی: DPPH,Antioxidant,Polygonatum orientale,12-Hydroxystigmast-4-en 3-one,Methyl oleate
- چکیده:
- چکیده انگلیسی: Polygonatum orientale Desf. (Asparagaceae) is herbaceous and perennial plant grown in northern parts of Iran. The rhizomes of Polygonatum, known as Iranian Shaghagho, is used in Iranian traditional medicine as tonic, aphrodisiac, wound healing, lightening, kidney stone remedy, gynecological and internal wounds healing, anti-gout and rheumatism, and anti-diabetic. The aim of this study was to evaluate 2,2 Diphenyl -1- Picryl Hydrazyl (DPPH) free radical scavenging activity, isolation, purification and identification of secondary metabolites from Polygonatum orientale Desf. rhizome collected from north of Iran. The 80% methanol extract from the rhizomes of P. orientale was partitioned between 80% methanol and hexan, chloroform, ethyl acetate, and n-butanol respectively. The inhibitory concentrations 50% (IC50) for ethyl acetate fraction and BHT were measured from the concentration-inhibition curve and were 315.02 μg/ml and 42.3 μg/ml, respectively. Chloroform fraction was loaded on silica gel chromatography column and eluted with hexane:ethyla cetate (90:10 to 100% ethyl acetate).Two major compounds, 12-Hydroxystigmast 4-en 3-one, a phytosteroid, and methyl oleate, a fatty acid ester, were isolated using TLC plates and identified by spectroscopic methods; H and 13C NMR. These major compounds have been reported for the first time from Polygonatum species. A further phytochemical study to find more compounds from this medicinal plant is recommended.
- انتشار مقاله: 29-10-1395
- نویسندگان: Seyede Nargess Sadati Lamardi,Sepideh Ghambariyan,Mohammad Reza Shams Ardekani,Gholamreza Amin
- مشاهده