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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Asia Pacific Journal of Medical Toxicology
- نوع مقاله: Journal Article
- کلمات کلیدی:
- چکیده:
- چکیده انگلیسی:
- انتشار مقاله: 20-08-1396
- نویسندگان: Reza Afshari,Reza Afshari,Reza Afshari
- مشاهده
- جایگاه : پژوهشی
- مجله: Asia Pacific Journal of Medical Toxicology
- نوع مقاله: Journal Article
- کلمات کلیدی: Allergy,Food,Intolerance,Non-Food,Nut
- چکیده:
- چکیده انگلیسی: Background: The prevalence of reported allergic diseases is higher in North-America than in other countries around the world. Further, certain types of allergies are more common in some geographic regions or amongst different ethnic populations. This phenomenon has not been well studied amongst the Persian population in the Canadian context; therefore, the current study aimed to compare the prevalence of perceived and diagnosed non-food and food allergies, and food intolerance between Canadians of Persian descent (CPD) and Canadians of European descent (CED), within a sample population of British Columbia residents, their family members and close friends.
Methods: Participants were recruited via convenience and snowball sampling, and information about allergy history was collected through in-person and telephone interviews. The prevalence of perceived and diagnosed allergies and food intolerances were compared between CPD and CED. In total, data was reported about 4,404 individuals.
Results: The prevalence of all perceived allergies was significantly higher amongst CED compared to CPD [RR (95%CI) = 2.33 (1.6, 3.3)]. A similar pattern was observed for diagnosed food and nut allergy. As well, no cases of perceived or diagnosed food intolerance were reported amongst Persians in the study population.
Conclusion: In conclusion, these findings have clinical implications for the treatment and prevention of allergies and food intolerance in BC and Canada. The disproportionate effect of allergies and food intolerance on Canadians of European descent warrants the implementation of targeted public health prevention measures. The genitival and environmental reasons for lack of food intolerance in Canadians of Persian descent should also be investigated.- انتشار مقاله: 19-01-1396
- نویسندگان: Angela Randall,Jane A Buxton,Reza Afshari
- مشاهده
- جایگاه : پژوهشی
- مجله: Asia Pacific Journal of Medical Toxicology
- نوع مقاله: Journal Article
- کلمات کلیدی: Poisoning,History,Datura Stramonium
- چکیده:
- چکیده انگلیسی: Background: Datura stramonium is a poisonous and common flowering plant that is a member of the Solanacae family. Datura poisonings are a rare occurrence in the 21st century, making toxicological information on this plant sparse. Historical information on Datura provides useful information on the clinical symptoms and characteristics of poisonings. This review looks at the state of knowledge on Datura’s chemical properties and clinical characteristics in the 18th and 19th century.
Methods: A literature review was conducted, and an online database search identified 197 articles. Ultimately 42 articles met the search criteria and were included for review.
Results: Medical literature on Datura focused predominantly on clinical poisonings, medical treatments, and identifying its chemical properties. Clinical poisonings included cases of accidental and intentional poisonings, and provided information on the age of patients, their symptoms, and treatments. Datura was also used to treat a variety of conditions, including asthma, inflammatory diseases, epileptic seizures, and hallucinations. Chemical experimentation on Datura commonly looked at isolating alkaloids and assaying their concentrations in various plant organs.
Conclusion: Historical literature on Datura shows that cases of poisoning were a common occurrence. These historical sources provide useful information on Datura poisoning’s clinical findings, and preliminary uses of Datura in medical treatments. Early chemical exploration of Datura also set the groundwork for future research.- انتشار مقاله: 20-08-1395
- نویسندگان: Michael Jonasson,Reza Afshari
- مشاهده
- جایگاه : پژوهشی
- مجله: Asia Pacific Journal of Medical Toxicology
- نوع مقاله: Journal Article
- کلمات کلیدی:
- چکیده:
- چکیده انگلیسی:
- انتشار مقاله: 18-04-1395
- نویسندگان: Farshad Palad,Karen Bartlett,Reza Afshari
- مشاهده
- جایگاه : پژوهشی
- مجله: Asia Pacific Journal of Medical Toxicology
- نوع مقاله: Journal Article
- کلمات کلیدی:
- چکیده:
- چکیده انگلیسی:
- انتشار مقاله: 09-02-1395
- نویسندگان: Reza Afshari,Reza Afshari,Reza Afshari
- مشاهده
- جایگاه : پژوهشی
- مجله: Asia Pacific Journal of Medical Toxicology
- نوع مقاله: Journal Article
- کلمات کلیدی: Aflatoxins,Chemical Hazard Release,Dioxins,Disease Burden,Foodborne Diseases
- چکیده:
- چکیده انگلیسی: All people need food. Unsafe foods; however, may cause diseases ranging from diarrhea to cancer. Chemicals in food are a worldwide health concern. In 2006, the World Health Organization (WHO) organized a consultation on the global burden of foodborne diseases. Work to estimate this burden began in 2007 and was carried out by the WHO Foodborne Disease Burden Epidemiology Reference Group (FERG), which included a Chemical and Toxins Disease Task Force. The results of 8 years of work were released in December 2015.
- انتشار مقاله: 26-08-1394
- نویسندگان: Herman Gibb,Brecht Devleesschauwer,P. Michael Bolger,Felicia Wu,Janine Ezendam,Julie Cliff,Marco Zeilmaker,Philippe Jean-Paul Verger,John Pitt,Janis Baines,Gabriel Adegoke,Reza Afshari,Yan Liu,Bas Bokkers,Henk Van Loveren,Marcel Mengelers,Esther Brandon,Arie Hendrik Havelaar,David C. Bellinger
- مشاهده
- جایگاه : پژوهشی
- مجله: Asia Pacific Journal of Medical Toxicology
- نوع مقاله: Journal Article
- کلمات کلیدی: Iran,Epidemiology,Bites and Stings,Indian Ocean,Marine Toxins
- چکیده:
- چکیده انگلیسی: Background: The Persian Gulf is a suitable habitat for various types of marine species. This study was conducted with the aim of determining the epidemiology and clinical findings of injuries inflicted by marine creatures in the Persian Gulf, south Iran. Methods: In this retrospective cross-sectional study, medical records of patients with diagnosis of marine animal exposures treated at 6 referral clinics in Bushehr province, south Iran, during 2009-2014 were studied. Results: Ninety-eight patients were studied whose mean (SD, Min - Max) age was 23.6 (7.0, 14-57) years. The majority of patients (91, 92.9%) were men. Scorpionfish stings were the most common cause of injuries (56.1%) followed by jellyfish stings (22.4%), stingray stings (13.3%) and sea urchin stings (8.2%). In most cases (60.2%), the location of injury was on lower limbs. The most common symptom was pain. Marked local swelling was detected in 69.1% of scorpionfish stings and 100% of stingray stings. Itching and hives were seen in 100% and 36.3% of jellyfish stung patients. Gastrointestinal manifestations were the most common systemic effects. Muscle cramps and transient local paralysis were reported in 38.7 % and 23 % of stingray patients, respectively. Serious systemic effects were rare except for symptomatic hypotension in a scorpionfish sting patient and syncope in a stingray sting patient. The vast majority of patients (93.9%) recovered without notable sequels. Secondary dermal infections were only observed in 1 stingray inflicted victim and 4 sea urchin stung victim. No death occurred. Conclusion: Scorpionfish attacks are the common cause of marine animal exposures in south Iran and should be taken seriously. Men at young ages are the victims of this environmental and occupational hazard.
- انتشار مقاله: 26-01-1394
- نویسندگان: Iraj Nabipour,Ali Reza Khoshdel,Ali Reza Golaghaei,Ahmad Tashakori Beheshti,Reza Afshari
- مشاهده
- جایگاه : پژوهشی
- مجله: Asia Pacific Journal of Medical Toxicology
- نوع مقاله: Journal Article
- کلمات کلیدی: Glasgow Coma Scale,Psychomotor agitation,Sedation,Unconsciousness,Weights and Measures
- چکیده:
- چکیده انگلیسی: Background: Few methods have been introduced to assess the level of consciousness in critically-ill patients. This study was designed to evaluate how the AlertVerbalPainfulUnresponsive (AVPU) responsive scale corresponds with the Glasgow Coma Scale (GCS) and Richmond Agitation-Sedation Scale (RASS) scores in drug-poisoned patients and to devise an augmented AVPU scale.
Methods: In this prospective study, patients with diagnosis of acute drug poisoning were included and their level of consciousness was assessed using GCS, RASS and AVPU scales.
Results: Overall, 165 poisoned patients (59% female) were studied. According to AVPU scale, 123 patients (74.5%) were graded as “alert”, 26 patients (15.8%) as “responsive to verbal stimulation”, 10 patients (6.1%) as “responsive to painful stimulation”, and 6 patients as “unresponsive” (3.6%). AVPU grades of "alert", "responsive to verbal stimulation", "responsive to painful stimulation" and "unresponsive" corresponded with median [IQR] GCS scores of 15 [15–15], 13 [12–13], 8 [7–10] and 6 [5–6], and median [IQR] RASS scores of -1 [-1 – +1], -2 [-3 – -1], -3 [-4 – -1], -5 [-5 – -5], respectively. By taking the median of RASS scores corresponding with each AVPU grade, an augmented AVPU scale for the assessment of consciousness was devised. The first proposed version of AVPU plus includes 14 qualitative grades of consciousness. By application of this scale, clinicians can evaluate both the alertness/attentiveness and arousal/excitability of poisoned and critical patients.
Conclusion: The AVPU plus is a new scale designed for more detailed assessment of neurologic status of poisoned and critical patients. The prognostic-ability, reliability and validity of the scale should be investigated in future studies.- انتشار مقاله: 16-01-1394
- نویسندگان: Ali Rajabi Kheirabadi,Jamshid Tabeshpour,Reza Afshari
- مشاهده
- جایگاه : پژوهشی
- مجله: Asia Pacific Journal of Medical Toxicology
- نوع مقاله: Journal Article
- کلمات کلیدی: Cost-benefit analysis,Comparative Effectiveness Research,Employee Performance Appraisal,Journal Impact Factor,Social Change
- چکیده:
- چکیده انگلیسی: Evaluation of scientists working in a specific area of science is necessary, as they may strive for same limited resources, grants and academic promotions. One of the most common and accepted methods of assessing the performance and impact of a scientist is calculating the number of citations for their publications. However, such method suffer from certain shortcomings. It has become more and more obvious that evaluation of scientists should be qualitative in addition to quantitative. Moreover, the evaluation process should be pragmatic and reflective of the priorities of an institution, a country or an intended population. In this context, a scoring scale called "360-degree researcher evaluation score" is proposed in this paper. Accordingly, scientists are evaluated in 5 independent domains including (I) science development, (II) economic impact, (III) policy impact, (IV) societal impact and (V) stewardship of research. This scale is designed for evaluation of impacts resulted from research activities and thus it excludes the educational programs done by a scientist. In general, it seems necessary that the evaluation process of a scientist’s impact moves from only scintometric indices to a combination of quantitative and qualitative indices.
- انتشار مقاله: 15-08-1393
- نویسندگان: Reza Afshari,Seyed Mostafa Monzavi
- مشاهده
- جایگاه : پژوهشی
- مجله: Asia Pacific Journal of Medical Toxicology
- نوع مقاله: Journal Article
- کلمات کلیدی: Poisoning,Carbon Monoxide,Brain,magnetic resonance imaging
- چکیده:
- چکیده انگلیسی: Background: Carbon monoxide (CO) poisoning may lead to hypoxic/anoxic injury and eventually ischemic encephalopathy. Magnetic resonance imaging (MRI) has a well-recognized role in assessment of the severity of brain damage caused by CO poisoning. In this study, we aimed to present and analyze the structural abnormalities in the brain MRI and especially in diffusion weighted MRI (DWI) images in a series of patients with acute CO poisoning.
Methods: This cross-sectional observational study was performed on patients with moderate to severe CO poisoning admitted to Mashhad Medical Toxicology Center of Imam Reza Hospital, Mashhad, Iran, during autumn and winter 2013. After stabilization, patients underwent brain MRI. T1 weighted, T2 weighted and FLAIR images in sagittal, axial and coronal sections, and DWI in axial sections were performed for each patient.
Results: Eighteen patients (77.8% men) were enrolled in this study with median age of 29.5 years. Eleven patients (61.1%) had abnormal MRI signals and in 7 cases no abnormality or nonspecific abnormalities were detected. The most common involved region in brain MRI was white matter (38.9%) followed by globus pallidus (33.3%). Patients with signal abnormality in brain MRI had significantly longer duration of exposure to CO compared to those without signal changes (10.6 ± 6.2 h vs. 3.4 ± 2.8 h, P = 0.011). Nine patients had restricted diffusion in DWI. Patients with restricted diffusion in DWI had also longer duration of exposure to CO compared to patients with normal DWI (12.1 ± 5.5 h vs. 3.5 ± 2.9 h, P = 0.001).
Conclusion: The white matter and globus pallidus were the most common affected regions in brain following acute CO poisoning. Signal abnormalities and restricted diffusion in MRI were correlated with duration of exposure to CO but not with the carboxyhemoglobin levels.- انتشار مقاله: 25-03-1393
- نویسندگان: Yasmin Davoudi,Bita Dadpour,Reza Afshari,Naser Hasaniyeh,Nassim Matin,Mahboobeh Rahimi-Doab
- مشاهده