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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Transactions on Combinatorics
- نوع مقاله: Journal Article
- کلمات کلیدی: topological index,degree,extremal graph theory
- چکیده:
- چکیده انگلیسی: Cruz, Monsalve and Rada [Extremal values of vertex-degree-based topological indices of chemical trees, Appl. Math. Comput. 380 (2020) 125281] posed an open problem to find the maximum value of the exponential second Zagreb index for chemical trees of given order. In this paper, we solve the open problem completely.
- انتشار مقاله: 01-07-1399
- نویسندگان: Selvaraj Balachandran,Tomas Vetrik
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Basic Medical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: Anti-inflammatory,Anti-antipruritic,Aristolochia indica,Mast cell stabilizing activity
- چکیده:
- چکیده انگلیسی: Objective(s) Aristolochia indica has been widely used in the traditional medicine for the treatment of a variety of diseases. In the present study different extracts of roots of A. indica were evaluated for their antiinflammatory, antipruritic and mast cell stabilizing activity. Materials and Methods Anti-inflammatory activity was performed by compound 48/80 induced rat paw edema model and antipruritic activity by examining the incidence of scratching behavior. Mast cell stabilizing activity was performed by compound 48/80 and sheep serum induced mast cell degranulation methods. Results The ethanol extract (300 mg/kg) and petroleum ether extract (100 mg/kg) were found to inhibit mast cell degranulation significantly equivalent to that of standard drug ketotifen (69%) by compound 48/80 model. In sheep serum model the ethanol extracts (150 and 300 mg/kg) and petroleum ether extract (100 mg/kg) showed good mast cell stabilizing activity (66-67%). Ethanol extract at 150 mg/kg showed 70% reduction of rat paw oedema and also significantly reduced the scratching response. Conclusion Results suggest A. indica has good mast cell stabilizing, anti-inflammatory and antipruritic activity.
- انتشار مقاله: 04-07-1394
- نویسندگان: Jessy Elizabeth Mathew,Srinivasan Keloth Kaitheri,Seekarajapuram DinakaranVachala,Magi Jose
- مشاهده
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: Diagnosis,Prevention,precancerous lesion
- چکیده:
- چکیده انگلیسی: Objective: Oral submucous fibrosis (OSMF) is a chronic precancerous condition affecting the oral cavity, which is progressive and characterised by burning sensation and fibrotic change leading to restriction of mouth opening. This study evaluated the morphology of soft palate in different stages of OSMF patients using digital lateral cephalogram and compare it with healthy individuals. Methods: The study included 60 subjects, who were grouped as 30 OSMF and 30 healthy subjects from the same geographic population. Digital lateral cephalograms were taken with Planmeca Proline XC (Oy, Helsinki, Finland). Soft palate morphology was evaluated using Lateral Cephalogram, and the results were analysed statistically. Results: Leaf-shaped (Type 1) soft palate was commonly seen in the control group and stage I and II OSMF. Stage III OSMF patients presented with a butt-shaped (Type 3) soft palate. As the disease progressed, there was a conversion of Type 1 variety of soft palate to Type 3 variety. There was a gradual reduction in the length of the soft palate in the anteroposterior direction in OSMF patients compared to the control group. Conclusion: Early cephalometric diagnosis of soft palate changes may play a pivotal role in the overall management of OSMF.
- انتشار مقاله: 24-02-1399
- نویسندگان: Manaswita Tripathy,Jayaprasad Anekar,Raj AC,Sandeepa N C,Deepika Napplli,Priya Lokanath,Abdulrahman Nahi Alharbi,Fahad Mohammed A Alsobil,Darshan Devang Divakar,Aftab Ahmed Khan,Chitra Jhugroo,Sanjeev Balappa Khanagar,Sachin Naik
- مشاهده