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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Progress in Chemical and Biochemical Research
- نوع مقاله: Journal Article
- کلمات کلیدی: Benzimidazole,Keywords: 2-nitroaniline,One pot reaction,Reductive cyclisation reaction
- چکیده:
- چکیده انگلیسی: Small amount of Zn dust and NaHSO3 was utilized to efficiently synthesize benzimidazole derivatives via one pot reductive cyclocondensation process in water medium at 100oC temperature. Very good to excellent yields in reasonably short reaction times, high atom economy and usage of readily available starting material, operational simplicity and easy workup are the fundamental features of this protocol.
- انتشار مقاله: 04-06-1399
- نویسندگان: Hridoydip Ranjan Dasgupta,Suvodip Mukherjee,Pranab Ghosh
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Medicinal and Chemical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: Psidium guajava,phytochemical investigation,triterpenoids,biocidal activity
- چکیده:
- چکیده انگلیسی: Phytochemical investigation of the pet-benzene extract of the leaves of Psidiumguajava was yielded the triterpenoids, olean-12(13), 15(16)-diene, olean-12(13), 15(16)-dien-3β-oland olean-15(16)-en-11α-ol. All the three compounds are reported for the first time from Psidiumguajava. The compounds were established by chemical characterized using IR, NMR, and Mass analysis by comparison with authentic sample. All the three triterpenoids showed moderate to good biocidal activity against some bacterial and fungal pathogens.
- انتشار مقاله: 24-12-1397
- نویسندگان: Pranab Ghosh,Rabindranath Singha,Md Golam Rasul
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Medicinal and Chemical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: Antimicrobial activity,Isolation,Triterpenoid,Taraxerone,Transformative reaction
- چکیده:
- چکیده انگلیسی: Although studies on oxidation of triterpenoid ketones with hydrogen peroxide and selenium dioxide have been reported, literature reports on the effect of theoxidizing agent on the oxime derivative of triterpenoid ketones are scanty. Thus in continuation of our previous studies on the transformative reactions on pentacyclic triterpenoids of lupane and friedelin skeleton and in order to examine the nature of the products formed on the oxidation of oxime derivatives of 3-keto-triterpenoids having gem dimethyl group at C4 and a double bond at ring D (between C14-C15), the oxidation of keto-oximes of taraxerone with hydrogen peroxide and selenium dioxidewas taken up and characterisation of the products (A -D) along with the evaluation of their preliminary biological activitywere studied in this work. The oxime derivative of taraxerone (1a) in tertiary butanol was refluxed with selenium dioxide and hydrogen peroxide. The residue obtained after recovery of solvent by distillation was extracted with ether and separated into neutral and acid parts using usual method.
- انتشار مقاله: 10-02-1398
- نویسندگان: Rabindranath Singha,Pranab Ghosh
- مشاهده
- جایگاه : پژوهشی
- مجله: Asian Journal of Green Chemistry
- نوع مقاله: Journal Article
- کلمات کلیدی: Aldehydes,Nitriles,Hydroxylaminehydrochloride,Silica-gel
- چکیده:
- چکیده انگلیسی: A green and facile methodology for the synthesis of nitrile has been established from the corresponding aldehydes and hydroxylamine hydrochloride on silica-gel in hot condition. The protocol is equally effective for aliphatic as well as aromatic aldehydes, and has wide range of functional group tolerance. In addition, this methodology is solvent-free, inexpensive, environmental friendly and involves simple work-up process.
- انتشار مقاله: 10-01-1397
- نویسندگان: Rakesh Ranjan Chakraborty,Pranab Ghosh
- مشاهده