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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Asian Journal of Green Chemistry
- نوع مقاله: Journal Article
- کلمات کلیدی: Antifungal activity,Antibacterial activity,Aldehyde,Azomethines,Aminomethyl phenol
- چکیده:
- چکیده انگلیسی: A series of azomethine and aminomethyl phenol derivatives has been synthesized and characterized by mass, IR, and NMR spectral techniques.In vitro antimicrobial activities of all these compounds were evaluated against different gram-positive and gram-negative bacterial and fungal strains by measuring zone of inhibition using agar diffusion method. Results of antimicrobial screening indicated that the compound 4a was the most active antimicrobial agent (100 µg/mL). The compounds 3a, 4e, 4f were exhibited best in vitro anti-microbial activity against the gram positive bacterial strains such as Bacillus subtilis, Micrococcus luteus and gram negativebacterialstrain Salmonella typhi andfungalstrain Candida albicans.
- انتشار مقاله: 03-07-1397
- نویسندگان: Sivakumar Matam,Prabakaran Kaliyan,Padmavathy Sethuramasamy,Seenivasa Perumal Muthu
- مشاهده
- جایگاه : پژوهشی
- مجله: Asian Journal of Green Chemistry
- نوع مقاله: Journal Article
- کلمات کلیدی: Aldehydes,Malononitrile,Knoevenagel product,Water extract of onion
- چکیده:
- چکیده انگلیسی: A useful method for Knoevenagel condensation has been developed from the reaction between active methylene compound 1 and aldehyde 2 using the water extract of onion as a green catalyst. This method is suitable for variety of aldehydes including, substituted aromatic, aliphatic, α, β-unsaturated, and heterocyclic with malononitrile or ethyl cyanoacetate, and affords the α-cyanoacrylonitriles and α-cyanoacrylatesin excellent yields (Up to 98%). The products are isolated without column chromatography. The use of water extract of onion has several advantages such as low price, easy handling, simple work up procedure and environmentally benign.
- انتشار مقاله: 07-04-1397
- نویسندگان: Prabakaran Kaliyan,Sivakumar Matam,Seenivasa Perumal Muthu
- مشاهده