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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: Iran,Prevalence,Meta-Analysis,Systematic review,neonate,Macrosomia
- چکیده:
- چکیده انگلیسی: Background: Macrosomia is a risk factor for adverse maternal and neonatal outcomes and previous studies have reported different prevalence of macrosomia in Iran. We conducted a meta-analysis to estimate the overall prevalence of macrosomia in Iran.
Materials and Methods: A systematic review and meta-analysis was conducted of all published literature pertaining to prevalence rates of macrosomia using international and national electronic databases ISI Web of Knowledge, PubMed, Scopus, SID, Magiran and Google Scholar from their inception until June 2017 with standard keywords. Egger test and Funnel plot were used to evaluate the publication bias and Cochran test and I2 statistics were used to examine the statistical heterogeneity. Pooled estimate of the prevalence of macrosomia were calculated using random effects meta-analysis.
Results: A total of 40 studies were included in this meta-analysis. The publication bias assumption was rejected Egger test (P=0.719) and Funnel plot. The results of Cochran test and I2 statistics revealed substantial heterogeneity (Q=1040.5.00, df = 39, P2=96.3%). The overall prevalence of macrosomia using the random effect model in Iran was 5.2% (95% confidence interval [CI]: 4.4-5.9). Moreover, the macrosomia prevalence in Tehran and other cities were 3.9% (95% CI: 3.2-4.7) and 6.0% (95% CI: 5.0-7.1), respectively.
Conclusion:The macrosomia rate in Iran is high. There is a critical need to improve the education and the gestational care and identifying at risk neonates to reduce the macrosomia rate and its adverse outcomes.
- انتشار مقاله: 27-03-1396
- نویسندگان: Saman Maroufizadeh,Amir Almasi-Hashiani,Arezoo Esmaeilzadeh,Maryam Mohammadi,Payam Amini,Reza Omani Samani
- مشاهده
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: Survival analysis,Stomach Neoplasm,Esophageal Neoplasm
- چکیده:
- چکیده انگلیسی: Background: Esophageal cancer (EC) and Gastric cancer (GC) have been identified as two of the most common
cancers in the northeastern regions of Iran. The increasing rates of these types of cancers requires attention. This study
aims to assess the potential risk factors for these two cancers and then determine shared risk factors between them
in a population of Iranian patients using parametric survival models. Methods: This retrospective cohort study was
conducted using 127 patients with EC and 184 patients with GC in East Azarbaijan, Iran who were diagnosed and
registered during the years 2009-2010 in Iran’s National Cancer Control Registration Program and were followed for
five years. Parametric survival models were used to find the risk factors of the patients. Akaike Information Criteria was
used to identify the best parametric model in this study. Interaction analysis was used to determine shared risk factors
between EC and GC. Results: The mean (±standard deviation) age of diagnoses for EC and GC were 66.92(±11.95) and
66.5(±11.5) respectively. The survival time ranges of GC patients was (0.07-70.33) and the survival time ranges were
from 0.10 to 69.03 months for EC patients. Multivariable Log- logistic model showed that being married (OR=2.25, 95%
CI: 1.33 - 3.81) for EC patients and Esophagectomy surgery for EC (OR: 1.62, 95% CI: 1.04 – 2.55) and GC (OR: 1.60,
95% CI: 1.02 – 2.53) had significant effects on survival. Age at the time of diagnosis, job status, and Esophagectomy
surgery were statistically comparable regarding their magnitude of effect on survival of two cancers (all Ps>0.05).
Conclusion: Esophagectomy surgery and being married were important risk factors in EC and GC. The log-logistic
model was the most appropriate statistical approach to identify significant risk factors on survival of both cancers.- انتشار مقاله: 17-01-1397
- نویسندگان: Elaheh Zarean,Payam Amini,Mehdi Yaseri,Morteza Hajihosseini,Tara Azimi,Mahmood Mahmoudi
- مشاهده
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: Survival analysis,Risk Factor,Esophageal Cancer
- چکیده:
- چکیده انگلیسی: Background: Esophageal cancer is one of the leading causes of death worldwide. The global increasing rate of this
type of cancer requires more attention. The purpose of this study was to determine the overall survival probability of
esophageal cancer after diagnosis and to assess the potential risk factors in a population of Iranian patients. Materials
and Methods: This retrospective cohort study was conducted on 127 cases with esophageal cancer in the Azarbaijan
province, East of Iran. Participants in the study were diagnosed during 2009-2010 and were followed up for 5 years. The
event was considered death due to esophageal cancer and those who survived until the end of the study were assumed as
right censored. Censored quntile regression was fitted to find the overall survival of the patients using adjusted effects of
variables and was compared with Cox regression model. Results: Patients’ mean and median survival time were 16.99
and 10.06 months respectively and 89% off cases died by the end of the study. The 1, 3, 6, 12 and 36-month survival
probabilities were 0.95, 0.76, 0.60, 0.43, and 0.18. The median survival time for females and males without surgery
were 21.79 and 14.76 month respectively. The accuracy of predictions were 0.99 and 0.74 for the censored quantile
regression and Cox, respectively. Conclusion: We concluded that being male, not having surgery, longer wait time
between having symptoms and being diagnosed, low socioeconomic status and old age to be significant risk factors in
reducing the probability of survival from esophageal cancer.- انتشار مقاله: 24-08-1396
- نویسندگان: Elaheh Zarean,Mahmoud Mahmoudi,Tara Azimi,Payam Amini
- مشاهده
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: Survival analysis,Esophageal Neoplasms,Non-mixture Cure fraction models
- چکیده:
- چکیده انگلیسی: Objective: Esophageal cancer (EC) is one of the gastrointestinal malignancies with a very high morbidity and
mortality rate due to poor prognosis. This study aims to assess the effects of risk factors on survival and cure fraction of
patients with EC in a population of Iranian patients using a non-mixture cure fraction model. Methods: This retrospective
cohort study was conducted on 127 patients with EC who were diagnosed during 2009-2010 and were followed
up for 5 years in East-Azarbaijan, Iran. Stepwise selection and non-mixture cure fraction model were used to find
the risk factors of EC survival patients. Results: The mean (±standard deviation) diagnosis age of the EC was
66.92(±11.95). One, three and five-year survival probabilities were 0.44 (95% confidence interval (CI): 0.36-0.54),
0.2 (95% CI: 0.14-0.28) and 0.13 (95% CI: 0.08-0.2) respectively. Female sex (Estimate=-0.99; 95% confidence interval
(CI): -1.41,-0.58; p-value<0.001), low level socioeconomic status (Estimate=0.39; 95%CI: 0.12,0.66; p-value=0.043),
the group who did not do esophagectomy surgery (Estimate=0.58; 95%CI: 0.17,0.99; p-value=0.005) and unmarried
group (Estimate=0.58; 95%CI: 0.11-1.05; p-value=0.015) were found as the significant predictor of survival and
cure fraction of the EC patients. Population cure rate was 0.11 (95%CI: 0.07-0.19) and Cure fraction was estimated
5.11 percent. Conclusion: This study found gender, socioeconomic status, Esophagectomy surgery and marital status
as the potential risk factors for survival and cure fraction of Iranian EC patients. Moreover, non- mixture cure fraction
provides more accurate and more reliable insight into long-term advantages of EC therapy compared to standard classic
survival analysis alternatives.- انتشار مقاله: 24-10-1396
- نویسندگان: Elaheh Zarean,Mehdi Azizmohammad Looha,Payam Amini,Mahmood Mahmoudi,Tara Azimi
- مشاهده