در هنگام جستجو کلمه در قسمت عنوان میتوانید کلمات مورد جستجو را با کاراکتر (-) جدا کنید.
کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Iranian Journal of Immunology
- نوع مقاله: Journal Article
- کلمات کلیدی: Apoptosis,calprotectin,Severe Early Childhood Caries,α-Defensins,Neutrophil
- چکیده:
- چکیده انگلیسی: Background: The infectious nature of severe early-childhood caries (S-ECC) points to the possible participation of immunologic host responses including neutrophils and their antimicrobial products.
Objectives: The aim of this study was to determine the neutrophil apoptosis, α-defensins (HNP1-3) and calprotectin levels in the saliva of preschool children and the association with S-ECC.
Methods: Oral examinations were performed on 87 children aged 3-5 years and non stimulated whole saliva samples were collected. Thirty of these subjects were considered S-ECC children, 30 with moderate caries (MC) and 27 were caries free (CF). To detect apoptosis, cell staining was done with Annexin-V-Fluos and propidium iodide, and they were analyzed by fluorescent microscopy. The concentration of α-defensins and calprotectin were assessed using ELISA.
Results: There were no statistical differences between groups considering the HNP1-3 or calprotectin salivary levels (p=0.06 and p=0.23, respectively). The HNP1-3 and calprotectin levels were negatively correlated and the correlation was significant in MC group (p=0.03). Lower levels of apoptotic neutrophils were obtained from CF subjects as compared with S-ECC children (p=0.03).
Conclusions: Our findings establish that apoptotic mechanisms could be implicated in the immunity responses associated with S-ECC. We cannot yet- انتشار مقاله: 15-05-1395
- نویسندگان: Lida Toomarian,Mandana Sattari,Nazanin Hashemi,Nikoo Tadayon,Alireza Akbarzadeh Baghban
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Finance
- نوع مقاله: Journal Article
- کلمات کلیدی: volatility,Excess Return,Anomaly,Five Factor model of Fama and French
- چکیده:
- چکیده انگلیسی: Prediction of stock returns is always one of the most important discussions of financial markets, which has led to introducing of various models to pricing financial assets, one of the most important of these models is to measure the surplus returns by Fama & French model was introduced in the form of a 5-factor model which, in spite of its satisfaction with the model, is still in conflict with many anomalies in the market, which the model can not explain, in the same way The purpose of this paper is to examine the strength of Five Factor Model of Fama & French (2015) for explaining volatility as a market anomaly.The sample consists of 168 companies listed in Tehran Stock Exchange. Portfolio Analysis is the approach of this paper for testing explanatory power of the Five Factor Model. Results show that profitability and investment factors couldn’t explain excess returns. This conclusion contradicts the model of Fama and French (2016).
- انتشار مقاله: 11-10-1348
- نویسندگان: Roya Mirzaei,Amir Abbas Sahebgharani,Nazanin Hashemi
- مشاهده