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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Archives of Bone and Joint Surgery
- نوع مقاله: Journal Article
- کلمات کلیدی: Osteoporosis,osteopenia,Bone mineral densitometry,Peri-menopause
- چکیده:
- چکیده انگلیسی: Background: The menopausal transition called perimenopause, happens after the reproductive years, and is
specified with irregular menstrual cycles, perimenopause symptoms and hormonal changes. Women going through
peri menopausal period are vulnerable to bone loss.
Osteoporosis is one of the most common debilitating metabolic bone diseases ,especially in the women almost
around 50 years .This study was intended to evaluate the prevalence of osteopenia/osteoporosis amongst
asymptomatic individuals during the menopause transition period.
Methods: A total of 714 asymptomatic peri-menopausal female volunteers were recruited through a billboard invitation
for participation in the study. The subjects were selected based on already defined inclusion and exclusion criteria.
The project, which was conducted between 2010 and 2014 was affiliated to the Educational and Therapeutic Center,
Imam Reza Hospital, Mashhad, Iran. Bone Mineral Densitometry (BMD) measured by DEXA (dual-energy X-ray
absorptiometry) was carried out on two distinct sites, the proximal femur and the lumbar vertebrae from L1 to L4.
Pertained data were analyzed.
Results: The mean age of the subjects was 49.7±2.years. The overall prevalence of osteopenia and osteoporosis
in these peri-menopausal individuals were 37.6 % and 10% respectively. Thirty five point two percent of 714 women
presented with osteopenia and eight percent of them have osteoporosis in the femoral neck, respectively. Nonetheless,
BMD values at the lumbar spine indicated 41.6% and 12% of individual participants being affected by osteopenia and
osteoporosis.
Conclusion: In general osteopenia or osteoporosis, occurred in 48% of this study population, implying that special
attention is required for the bone health status of Iranian women who undergo menopause.- انتشار مقاله: 15-08-1395
- نویسندگان: Zhaleh Shariati-Sarabi,Hamid Etemad Rezaie,Nasrin Milani,Farnaz Etemadrezaee,Ali Etemad Rezaie
- مشاهده
- جایگاه : پژوهشی
- مجله: Reviews in Clinical Medicine
- نوع مقاله: Journal Article
- کلمات کلیدی: hypertension,Risk Factor,Vitamin D
- چکیده:
- چکیده انگلیسی: Introduction: Hypertension (HTN) is one of the most life-threatening disorders worldwide. Although some examinations have demonstrated an incidental relationship between blood pressure and serum level of 25-hydroxyvitamin D, there have been new exchanges of views with respect to the influence of low vitamin D levels in hypertension. This study aims to find out the relationship between hypertension and regular consumption of vitamin D.
Methods: A case-control study was conducted with regard to secondary data (SINA system) among people, aged 30 years old or older, registered in 2017-2018. A sample size of 1,500 patients was used comprising of 500 patients with hypertension as the case group and 1,000 people without history of hypertension as the control group. The population was selected randomly. High blood pressure diagnostic criteria were considered in the same manner with the clinical guidelines of the 7th National Joint Committee. Data were analyzed using SPSS 22 software.
Results: Regular consumption of vitamin D had a protective role on hypertension (P value <0.05) and [OR= 0.421 (0.353- 0.505)].
Conclusion: By identifying hypertension risk factors, taking measures to prevent it would be more practical and the risk of hypertension can be reduced. An enormous volume of epidemiological and empirical proof is indicative of the fact that vitamin D deficiency can lead to high blood pressure. The present investigation proves that vitamin D supplementary may serve as a convenient method to diminish the risk of progression of increased blood pressure due to its protective effect on blood pressure.- انتشار مقاله: 11-12-1398
- نویسندگان: Nasrin Milani,Mohamad Sajjadi-Manesh,Ehsan Mousa-Farkhani,Ali Taghipour
- مشاهده
- جایگاه : پژوهشی
- مجله: Reviews in Clinical Medicine
- نوع مقاله: Journal Article
- کلمات کلیدی: Prevalence,Risk Factor,Gestational Diabetes Mellitus
- چکیده:
- چکیده انگلیسی: Introduction: Diabetes is the most common metabolic disorder during pregnancy. Given the importance of the screening and treatment of gestational diabetes for the prevention of maternal and fetal complications, the present study aimed to evaluate the prevalence of gestational diabetes mellitus in the pregnant women covered by Mashhad University of Medical Sciences, Iran.
Methods: This study was conducted on the women with pregnancy intention or confirmed pregnancy, referring to the health centers affiliated to Mashhad University of Medical Sciences during March 2017-September 2018. The patients with gestational diabetes mellitus were identified based on the latest WHO criteria in 2013. Data were collected on the conducted experiments and recorded in the integrated health information system (SINA). Data analysis was performed in SPSS version 25 using Chi-square and logistic regression.
Results: During the study period, 2,710 women (4.3%) were diagnosed gestational diabetes mellitus. The mean age of the patients was 28.5656.379 years. In terms of the influential factors, significant correlations were observed between gestational diabetes mellitus and family history of diabetes (OR=4.278; P<0.0001), history of gestational diabetes mellitus (OR=3.880; P<0.0001), body mass index (OR=2.302; P<0.0001), history of macrosomia (OR=1.656; P<0.003), history of recurrent miscarriage (OR=1.759; P<0.007), and preeclampsia (OR=1.914; P<0.045).
Conclusion: According to the results, the prevalence of diabetes in Mashhad city (4.3%) seems to be slightly lower than other areas. Special attention must be paid to the pregnant women with the influential factors of gestational diabetes mellitus through selective screening based on the risk factors of the disease.- انتشار مقاله: 12-12-1398
- نویسندگان: Kazem Saeedi,Ali Taghipour,Ehsan Mousa-Farkhani,Nasrin Milani
- مشاهده
- جایگاه : پژوهشی
- مجله: Reviews in Clinical Medicine
- نوع مقاله: Journal Article
- کلمات کلیدی: hypertension,Risk Factor,Vitamin D
- چکیده:
- چکیده انگلیسی: Introduction: Hypertension (HTN) is one of the most life-threatening disorders worldwide. Although some examinations have demonstrated an incidental relationship between blood pressure and serum level of 25-hydroxyvitamin D, there have been new exchanges of views with respect to the influence of low vitamin D levels in hypertension. This study aims to find out the relationship between hypertension and regular consumption of vitamin D.
Methods: A case-control study was conducted with regard to secondary data (SINA system) among people, aged 30 years old or older, registered in 2017-2018. A sample size of 1,500 patients was used comprising of 500 patients with hypertension as the case group and 1,000 people without history of hypertension as the control group. The population was selected randomly. High blood pressure diagnostic criteria were considered in the same manner with the clinical guidelines of the 7th National Joint Committee. Data were analyzed using SPSS 22 software.
Results: Regular consumption of vitamin D had a protective role on hypertension (P value <0.05) and [OR= 0.421 (0.353- 0.505)].
Conclusion: By identifying hypertension risk factors, taking measures to prevent it would be more practical and the risk of hypertension can be reduced. An enormous volume of epidemiological and empirical proof is indicative of the fact that vitamin D deficiency can lead to high blood pressure. The present investigation proves that vitamin D supplementary may serve as a convenient method to diminish the risk of progression of increased blood pressure due to its protective effect on blood pressure.- انتشار مقاله: 11-12-1398
- نویسندگان: Nasrin Milani,Mohamad Sajjadi-Manesh,Ehsan Mousa-Farkhani,Ali Taghipour
- مشاهده
- جایگاه : پژوهشی
- مجله: Reviews in Clinical Medicine
- نوع مقاله: Journal Article
- کلمات کلیدی: Prevalence,Risk Factor,Gestational Diabetes Mellitus
- چکیده:
- چکیده انگلیسی: Introduction: Diabetes is the most common metabolic disorder during pregnancy. Given the importance of the screening and treatment of gestational diabetes for the prevention of maternal and fetal complications, the present study aimed to evaluate the prevalence of gestational diabetes mellitus in the pregnant women covered by Mashhad University of Medical Sciences, Iran.
Methods: This study was conducted on the women with pregnancy intention or confirmed pregnancy, referring to the health centers affiliated to Mashhad University of Medical Sciences during March 2017-September 2018. The patients with gestational diabetes mellitus were identified based on the latest WHO criteria in 2013. Data were collected on the conducted experiments and recorded in the integrated health information system (SINA). Data analysis was performed in SPSS version 25 using Chi-square and logistic regression.
Results: During the study period, 2,710 women (4.3%) were diagnosed gestational diabetes mellitus. The mean age of the patients was 28.5656.379 years. In terms of the influential factors, significant correlations were observed between gestational diabetes mellitus and family history of diabetes (OR=4.278; P<0.0001), history of gestational diabetes mellitus (OR=3.880; P<0.0001), body mass index (OR=2.302; P<0.0001), history of macrosomia (OR=1.656; P<0.003), history of recurrent miscarriage (OR=1.759; P<0.007), and preeclampsia (OR=1.914; P<0.045).
Conclusion: According to the results, the prevalence of diabetes in Mashhad city (4.3%) seems to be slightly lower than other areas. Special attention must be paid to the pregnant women with the influential factors of gestational diabetes mellitus through selective screening based on the risk factors of the disease.- انتشار مقاله: 12-12-1398
- نویسندگان: Kazem Saeedi,Ali Taghipour,Ehsan Mousa-Farkhani,Nasrin Milani
- مشاهده
- جایگاه : پژوهشی
- مجله: Asia Pacific Journal of Medical Toxicology
- نوع مقاله: Journal Article
- کلمات کلیدی: Acetaminophen,rhabdomyolysis,Kidney Injury
- چکیده:
- چکیده انگلیسی: Background: Rhabdomyolysis is a clinical syndrome that results in releasing myoglobin content from damaged muscle cells into circulation and often causes acute kidney injury (1). Different mechanisms are considered to be responsible in rhabdomyolysis and renal failure. However, free radical generation is the most important mechanism resulting in kidney injury. Thus, the effect of various antioxidants has been investigated. Acetaminophen, with antioxidant ability in therapeutic dose, has shown a considerable protective effect on kidney after muscle injury. The investigations have shown that acetaminophen enhances renal function, decreases renal damage and reduces oxidant injury. The aim of this review was to summarize proven evidences for etiology to renal injury and abilities of acetaminophen in reducing it.
Methods: Articles published from 2010 to 2017 in PubMed and Google Scholar were covered in this review. The articles investigating the role of free radical in renal injury following Rhabdomylosis were searched using the keywords Rhabdomyolysis, kidney and oxidative stress. The keywords used to find articles regarding antioxidant ability of acetaminophen were antioxidant and acetaminophen.
Conclusion: With assessment of evidences form antioxidant capacity of acetaminophen and mechanism of renal failure in Rhabdomyolysis, this drug can be useful for prevention and treatment of kidney injury especially following rhabdomyolysis.- انتشار مقاله: 26-09-1397
- نویسندگان: Marjan Emzhik,Pouran Makhdoumi,Nasrin Milani,Bita Dadpour
- مشاهده