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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Journal of Oral Health and Oral Epidemiology
- نوع مقاله: Journal Article
- کلمات کلیدی: neoplasm,fibrous tumor,solitary tumor
- چکیده:
- چکیده انگلیسی: BACKGROUND AND AIM: Solitary fibrous tumor (SFT) is a quite uncommon tumor that commonly occurs in the pleura but occasionally involves an oral cavity. We are reporting this rare case in the oral cavity. The diagnosis depends on microscopic and immunohistochemical features. Patients with these tumors can be carefully treated with local excision, but tumors with positive margins necessitate close follow-up over several years due to the possible late local recurrence.
CASE REPORT: A 60-year malepatient came in the maxillofacial department in Abbasi Shaheed Hospital, Karachi, Pakistan with swelling for the past 5 years which slowly increased in size with no history of pain. The excisional biopsy was performed under local anesthesia. Histopathological examination showed a well-circumscribed spindle cell tumor with alternating hypo and hypercellular areas with prominent collagenous stroma. Immunohistochemistry (IHC) investigation led to the positive expression of Cluster of Differentiation 34 (CD34) and Signal Transducer and Activator of Transcription-6 (STAT-6) in the spindle cells, and negative expression of Anti-Smooth Muscle Antibody (ASMA). Recurrent or postoperative complications were not observed over some time.
CONCLUSION: SFT in the buccal mucosa of the cheek is a very sporadic condition. It needs to be identified with proper history and clinical examination.- انتشار مقاله: 11-10-1398
- نویسندگان: Sahar Usman,Zahid Ali,Sana Iqbal,Ayesha Aslam,Nasir Ud Din
- مشاهده
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: Lymphoma,Carcinoma,Synchronous,Metachronous,Concomitant
- چکیده:
- چکیده انگلیسی:
Case reports and case series documenting unfortunate patients with more than one malignant neoplasm are rare but well established. While majority of such patients have two malignancies, cases with three or even four malignant neoplasms in the same patient have been published in literature. A number of factors influencing carcinogenesis have been implicated in such cases including exposure to large amounts of radiation, chemotherapy for the original malignancy; prolonged history of heavy smoking and exposure to other environmental carcinogens; aging; and underlying genetic alterations. Concomitant multiple malignant neoplasms may be synchronous-two or more malignant neoplasms histologically distinct from each other, arising in the same site and detected simultaneously (for example during the same hospital admission) or detected one after the other in sequence in a period less than 6 months; or metachronous-two or more malignant neoplasms of similar or distinct histologic type detected at different times (after an interval of greater than 6 months) in different anatomic sites. Any combination of malignant tumors can occur in the same patient for example carcinomas with other carcinomas, carcinomas with Non-Hodgkin or Hodgkin lymphomas, carcinomas with mesotheliomas, carcinomas with sarcomas etc. We have reported several cases with multiple malignancies during our practice, and these cases were composed of the different combinations described above. The aim of the present study is to document 10 such cases of combined carcinoma and Non Hodgkin lymphoma in the same patient which were diagnosed in our section.- انتشار مقاله: 27-10-1395
- نویسندگان: Nasir Ud Din,Zubair Ahmad,Khurram Minhas,Zeeshan Uddin,Arsalan Ahmed
- مشاهده