در هنگام جستجو کلمه در قسمت عنوان میتوانید کلمات مورد جستجو را با کاراکتر (-) جدا کنید.
کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Journal of Oral Health and Oral Epidemiology
- نوع مقاله: Journal Article
- کلمات کلیدی: Diabetes Mellitus,Oral manifestation,Decayed Missing Filled Teeth,Periodontal Disease Index,Salivary Glucose
- چکیده:
- چکیده انگلیسی: OBJECTIVE: Oral manifestations in diabetic patients can have different causes. Possibly, one of these causes is salivary glucose. The aim of this study was to evaluate salivary glucose concentrations in patients with Type II diabetes mellitus (DM) and their association with oral and dental manifestations and compare them with normal adults. MATERIALS AND METHODS: In this analytical study, 128 patients with Type II DM and 132 non-diabetic healthy individuals were selected. The subjects’ blood and unstimulated salivary samples were collected. Salivary glucose concentrations were measured by glucose oxidase method. Then, the oral cavity and teeth were examined for oral manifestations such as ulcers, white and red plaques, lichenoid reaction, candidiasis and decayed missing filled teeth (DMFT) and periodontal disease index (PDI) indices. Data were analyzed by independent t-test and Pearson’s correlation test. RESULTS: The results of the present study showed that, in general, individuals with higher concentrations of salivary glucose had significantly higher DMFT and PDI, irrespective of belonging to the diabetic or the control group (P < 0.050). However, there was no significant correlation between salivary glucose concentrations and oral manifestations. Meanwhile, there was a significant correlation between salivary glucose concentration and glycated hemoglobin in diabetic patients compared with the control group (P < 0.001). CONCLUSION: The present study showed that the salivary glucose concentration had a positive association with DMFT and PDI in diabetic and non-diabetic patients. In this study, we found an association between salivary and blood glucose in diabetic patients.
- انتشار مقاله: 16-07-1393
- نویسندگان: Shahla Kakoei,Bahareh Hosseini,Ali Akbar Haghdoost,Mojgan Sanjari,Maryam Alsadat Hashemipour,Ahmad Gholamhosseinian
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Kerman University of Medical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: Efficacy,safety,Rosa damascene,Acarbose
- چکیده:
- چکیده انگلیسی: Background: Diabetes is a global health problem that its prevalence is increasing rapidly. Rosa damascena extract has shown to have an intensive non-competitive inhibitory effect on α-glucosidase in an animal study. The aim of this study was to assess the safety and efficacy of Rosa damascena (RD) Mill in diabetic patients and healthy subjects. Methods: In a triple-blind, placebo and Acarbose-controlled randomized trial in Kerman in the south-east of Iran, we randomly allocated diabetic patients (n=32) and healthy volunteers (n=28) to 100mg Acarbose, 200 mg RD-methanolic extract, 400mg RD-methanolic extract and placebo groups. Over 15 days, the participants were followed up to monitor the changes in blood biochemical parameters and apparent symptoms. Analyses were carried out by intention to treat. Results:RD extract decreased postprandial blood glucose levels comparable to the effects of Acarbose, demonstrating its α-glucosidase inhibitory activity. Besides, fasting plasma glucose levels significantly decreased in patients treated with 400 mg/day RD-methanolic extract compared to the 200 mg RD-methanolic extract (127.6±26.8vs. 165.5±27.1, p=0.041), suggesting that Rosa damascena Mill is effective in a dose dependent manner. No major or minor hypoglycemic event was observed. NO adverse event was observed in the RD treatment groups in comparison with Acarbose or placebo groups. Serum levels of biochemical parameters did not fluctuate significantly in RD treatment groups compared to Acarbose and placebo controls. Conclusion:Rosa damascena not only decreases blood glucose levels, but also is safe to be used for the purpose of controlling blood glucose levels in drug naïve patients with type II diabetes.
- انتشار مقاله: 19-10-1397
- نویسندگان: Mojgan Sanjari,Ahmad Gholamhoseinian Najar,Gholamreza Asadikaram,Mahboubeh Mashayekhi,Amirfarhad Ghaseminejad Tafreshi
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Advances in Medical Education and Professionalism
- نوع مقاله: Journal Article
- کلمات کلیدی: Medical students,Education,Medical assessment
- چکیده:
- چکیده انگلیسی: Introduction: Clinical reasoning as a critical and high level of clinical competency should be acquired during medical education, and medical educators should attempt to assess this ability in medical students. Nowadays, there are several ways to evaluate medical students’ clinical reasoning ability in different countries worldwide. There are some well-known clinical reasoning tests such as Key Feature (KF), Clinical Reasoning Problem (CRP), Script Concordance Test (SCT), and Comprehensive Integrative Puzzle (CIP). Each of these tests has its advantages and disadvantages. In this study, we evaluated the reliability of combination of clinical reasoning tests SCT, KF, CIP, and CRP in one national exam and the correlation between the subtest scores of these tests together with the total score of the exam.
Methods: A total of 339 high ranked medical students from 60 medical schools in Iran participated in a national exam named “Medical Olympiad”. The ninth Medical Olympiad was held in Shahid Beheshti University of Medical Sciences, Tehran, Iran, under the direct supervision of the Ministry of Health and Medical Education in summer 2017. The expert group designed a combination of four types of clinical reasoning tests to assess both analytical and non-analytical clinical reasoning. Mean scores of SCT, CRP, KF, and CIP were measured using descriptive statistics. Reliability was calculated for each test and the combination of tests using Cronbach’s alpha. Spearman’s correlation coefficient was used to evaluate the correlation between the score of each subtest and the total score. SPSS version 21 was used for data analysis and the level of significance was considered <0.05.
Results: The reliability of the combination of tests was 0.815. The reliability of KF was 0.81 and 0.76, 0.80, and 0.92 for SCT, CRP, and CIP, respectively. The mean total score was 169.921±41.54 from 240. All correlations between each clinical reasoning test and total score were significant (P<0.001). The highest correlation (0.887) was seen between CIP score and total score.
Conclusion: The study showed that combining different clinical reasoning tests can be a reliable way of measuring this ability.- انتشار مقاله: 14-02-1398
- نویسندگان: ANAHITA SADEGHI,ALI ALI ASGARI,NEZARALI MOULAEI,VAHID MOHAMMADKARIMI,SOMAYEH DELAVARI,MITRA AMINI,SETAREH NASIRI,ROGHAYEH AKBARI,MOJGAN SANJARI,IRAJ SEDIGHI,PARISA KHOSHNEVISASL,MANOUCHEHR KHOSHBATEN,SAEED SAFARI,LEILY MOHAJERZADEH,PARISA NABEIEI,BERNARD CHARLIN
- مشاهده