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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Iranian Journal of Medical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: Overweight,Coronary Artery Disease,Obesity,adolescents
- چکیده:
- چکیده انگلیسی: Background: Coronary artery disease is considered as the most common cause of death in all societies including Iran. This study seeks to compare the new risk factors of coronary-artery diseases in obese adolescents and control group.Methods: In this cross-sectional study, amongst the obese adolescents registered in the nutrition clinic of Ghaem Hospital, 80 individuals were selected. As the control group, additional 80 adolescent students having the same gender and age as the obese group, but with normal weight were selected. These two groups were selected randomly and their serum level of vitamin D, anti-heat shock protein27 (HSP27), balance of oxidants and antioxidants, and homocysteine were determined and compared. Results: In this study, 42 (53.2%) and 37 (46.8%) of the obese and normal weight groups were male, respectively. The mean value of triglyceride, cholesterol, and LDL in the obese group was higher than the normal group, but the mean value for HDL, vitamin D, homocysteine, PAB (Preoxidant and Antioxidants Balance), and anti-HSP27 was not significantly different between the groups. In the base of homocysteine >15 µmol/l, 26.6% of the obese group had hyperhomocysteinemia, therefore homocysteine may be a new risk factor for coronary artery disease in obese adolescents (χ2=4.072; P value=0.091). Conclusion: The findings of this study showed that despite the presence of obesity in adolescence and adolescents, new risk factors are not present among them more than the control group. This was in contrast to what was seen in adults.
- انتشار مقاله: 17-03-1394
- نویسندگان: Samaneh Kouzehgaran,Rahim Vakili,Mohsen Nematy,Mohamad Safarian,Majid Ghayour-Mobarhan,Mohamad Khajedaluee
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Basic Medical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: Glucose control,Heat shock protein 27,Parenteral Nutrition,Traumatic brain injury
- چکیده:
- چکیده انگلیسی: Objective(s):Hyperglycemia worsens the neuronal death induced by cerebral ischemia. Previous studies demonstrated that diabetic hyperglycemia suppressed the expression of heat shock protein 70 and 60 (HSP70 and 60) in the liver. IgG antibody titres against heat shock protein 27 (anti HSP27) were measured to determine whether hyperglycemia exacerbates ischemic brain damage by suppressing the expression of heat shock protein 27 (HSP27) in the brain. Materials and Methods: A randomized controlled study of traumatic brain injury ICU patients treated either by intensive insulin treatment (IIT) or by conventional glucose control (CGC) was conducted. Patients received at least 50% of their estimated daily energy requirements parenterally. Serum anti HSP27 antibody concentration was assessed at baseline, day 7 and day 14. Results: Twenty-six out of 29 patients (n=13 in each group) completed the study. At baseline, there were no differences between the two groups. On day 14, there was a significant reduction in anti HSP27 titre concentration in the IIT compared to the GCG group (0.47±0.27 mg/dl vs 0.60±0.15 mg/dl, P=0.03). Conclusion: In this study, intensive control of traumatic brain injury patients on parenteral nutrition reduced anti HSP27 titre, possibly suggesting a reduction in stress.
- انتشار مقاله: 29-11-1392
- نویسندگان: Seyedeh Neda Mousavi,Fariborz Samini,Mohsen Nematy,Elena Philippou,Mohammad Safarian,Shima Tavallaiee,Abdolreza Norouzy
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: Obesity,Life style,Pediatric,Traditional,Persian Medicine
- چکیده:
- چکیده انگلیسی: Obesity is a major risk factor for many diseases in children. Considering the widespread pandemic of pediatric obesity, developing more strategies for life style management of this disorder is essential. Therefore it was decided to conduct a more comprehensive study for prevention and treatment children obesity based on Traditional Persian Medicine (TPM). In this review we searched the most important TPM textbooks (such as Al-Havi, Al-qanun fit-tib, Kamel al Sanaeh), Classical Medicine (CM) text book (Krause's Food and the Nutrition Care Process), and scientific databases such as Data sources included (Medline, Scopus, Embase, Google Scholar) the period from 2000 to 2017 in terms of obesity management. The keywords Saman Mofrat, Setteh-e-Zarurieah, lifestyle, pediatric, children and obesity have been used in this search.
Based on TPM the six essential principles (Setteh-e-Zarurieah) must be observed in management of pediatric obesity that these essential factors are as follows: air, food and drink, sleep and wakefulness, evacuation and retention, body movement, mental movement and repose. Unhealthy lifestyle for example irregular sleep, constipation, overeating and wrong nutritional habits, insufficient physical activity, and emotional excitement, such as sadness and anxiety are plays an important role in obesity that confirmed by classical medicine. Moreover, TPM has a particular attention to the type of nutrients and their temperament and the children’s digestion ability. So, further clinical trials should be performed to confirm the long-term efficacy of healthy lifestyle in pediatric obesity management.- انتشار مقاله: 23-11-1396
- نویسندگان: Leily Hamidnia,Mohsen Nematy,Ali Taghipour,Roghayeh Javan,Roshanak Salari,Marjan Mahjour,Malihe Motavasselian
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: Glutaric Academia,Medical Treatment,Neurological Damage
- چکیده:
- چکیده انگلیسی: Introduction:
Glutaric academia type I is a metabolic disorder that is caused due to deficiency of glutaryl-CoA dehydrogenase. Macrocephaly is a common sign in GA1, although many infants usually appear healthy at birth.
Case Report
A 5.5 year old boy with GA1was admitted to NICU. Chief compliance of patient for hospitalization was pneumonia and sepsis and he was intubated and mechanically ventilated. This disease was diagnosed with signs of set developmental delay at 8 months oldand during these years; he was under control for nutritional counseling with a nutritionist and pediatrician. Nutritional support for this patient was in NICU.
Conclusion
Medical treatment combined with nutritional support in GA1 managementsigns of serious illness; also dietary treatment control may are needed to reduce progression of the neurological damage.- انتشار مقاله: 07-09-1392
- نویسندگان: Zarin Banikazemi,Mohsen Mazidi,Mohsen Nematy
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: Glutaric Academia,Medical Treatment,Neurological Damage
- چکیده:
- چکیده انگلیسی: Introduction:
Glutaric academia type I is a metabolic disorder that is caused due to deficiency of glutaryl-CoA dehydrogenase. Macrocephaly is a common sign in GA1, although many infants usually appear healthy at birth.
Case Report
A 5.5 year old boy with GA1was admitted to NICU. Chief compliance of patient for hospitalization was pneumonia and sepsis and he was intubated and mechanically ventilated. This disease was diagnosed with signs of set developmental delay at 8 months oldand during these years; he was under control for nutritional counseling with a nutritionist and pediatrician. Nutritional support for this patient was in NICU.
Conclusion
Medical treatment combined with nutritional support in GA1 managementsigns of serious illness; also dietary treatment control may are needed to reduce progression of the neurological damage.- انتشار مقاله: 07-09-1392
- نویسندگان: Zarin Banikazemi,Mohsen Mazidi,Mohsen Nematy
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: Glutaric Academia,Medical Treatment,Neurological Damage
- چکیده:
- چکیده انگلیسی: Introduction:
Glutaric academia type I is a metabolic disorder that is caused due to deficiency of glutaryl-CoA dehydrogenase. Macrocephaly is a common sign in GA1, although many infants usually appear healthy at birth.
Case Report
A 5.5 year old boy with GA1was admitted to NICU. Chief compliance of patient for hospitalization was pneumonia and sepsis and he was intubated and mechanically ventilated. This disease was diagnosed with signs of set developmental delay at 8 months oldand during these years; he was under control for nutritional counseling with a nutritionist and pediatrician. Nutritional support for this patient was in NICU.
Conclusion
Medical treatment combined with nutritional support in GA1 managementsigns of serious illness; also dietary treatment control may are needed to reduce progression of the neurological damage.- انتشار مقاله: 07-09-1392
- نویسندگان: Zarin Banikazemi,Mohsen Mazidi,Mohsen Nematy
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: Factor analysis,DIETARY PATTERNS,Early menarche,Food frequency questionnaire
- چکیده:
- چکیده انگلیسی: Background: The average age at menarche (AAM) has declined around the world, which is widely attributed to improvements in nutrition. This study was conducted to investigate the association between dietary patterns and early menarche ( Materials and Methods: This case-control study was carried out on 400 elementary school girls (200 early menarche and 200 premenarche) who were aged 12 years old and over, in Kermanshah, Iran, 2015. The participants were selected by cluster sampling from three areas of Kermanshah city. Body mass index (BMI) was calculated, and information on dietary intake was investigated by using a semi-quantitative food frequency questionnaire, which consists of 160 items and were filled by students’ parents. Logistic regression was performed to find a relationship between dietary patterns and risk of early menarche.
Results: The means age for the case and control groups (n=200, n=200) were 12.06±0.1 5 years and 12.0 6±0. 10 years, respectively. Four major dietary patterns of meat, western, vegetarian, and traditional were identified. After adjusting for the confounding factors, vegetarian (OR: 0.01; 95%CI: 0.003-0.02; P<0.001), and traditional (OR: 0.13; 95%CI: 0.06-0.26; P<0.001), dietary patterns were found to be negatively associated with early menarche whereas the highest tertile of meat dietary pattern (OR:1.21; 95%CI: 0.64-2.29; P<0.009), and BMI (OR: 3.36; 95%CI: 1.72-6.54) were positively associated with early menarche. Western diet showed no relationship with early age at menarche (P>0.05).
Conclusion: Based on the results, dietary patterns and body size were found to be related to early menarche among elementary school girls.- انتشار مقاله: 02-07-1398
- نویسندگان: Akram Rahimi,MehrAli Rahimi,Abdolreza Norouzy,Habibollah Esmaily,Peyman Eshraghi,Seyed Amir Reza Mohajeri,Mohsen Nematy
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Community Based Nursing and Midwifery
- نوع مقاله: Journal Article
- کلمات کلیدی: Diet,Fat,Ovarian cyst
- چکیده:
- چکیده انگلیسی: Background: Functional ovarian cysts (FOC) are one of the most common gynecological problems among women of reproductive age. Some studies have shown that diet may affect the function of the ovaries, so this study was performed to determine the association between the amount of dietary fat and functional ovarian cysts.Methods: This case-control study was performed on 264 female patients (132 with cyst in the case group and 132 in the control group) aged 13 to 49. The case group had ovarian cyst with a size of less than 8 cm and the control group didn’t have any ovarian cyst. Data were collected by questionnaires including a demographic questionnaire, and medical and midwifery characteristics questionnaire; the amount of fat in the diet was measured using food frequency questionnaire (FFQ). Data were analyzed using SPSS software. P
- انتشار مقاله: 24-02-1394
- نویسندگان: Mahin Tafazoli,Elham Fazeli,Salameh Dadgar,Mohsen Nematy
- مشاهده
- جایگاه : پژوهشی
- مجله: Avicenna Journal of Phytomedicine
- نوع مقاله: Journal Article
- کلمات کلیدی: Diet,Functional food,Blood rheology,Blood viscosity,Polycythemia
- چکیده:
- چکیده انگلیسی: Objective: Key hemorheological variables are associated with several life-threatening diseases including cardio-cerebro-vascular diseases. A diet can influence the blood rheological variables. To compare the effectiveness of a vegetable soup on blood viscosity (BV), hematocrit (Hct), plasma fibrinogen, lipid profile, fasting blood sugar (FBS), and blood osmolarity in patients with polycythemia in comparison to a control group.
Materials and Methods: This randomized controlled trial study was conducted at Isar health clinics in Mashhad, Iran, during a 7-month period. Forty male participants (35 to 60 years old) with polycythemia, but without underlying diseases, were included. They randomly assigned to two groups and either received diet/phlebotomy or phlebotomy alone, for 6 weeks. The data were analyzed by SPSS version 16 using parametric tests.
Results: A significant reduction in BV at 30s (p 0.001), BV at 40s (p 0.001), BV at 50s (p 0.001), Hct (p 0.001), plasma fibrinogen (p<0.001), total cholesterol (p<0.01), LDL-cholesterol (p<0.01), VLDL-cholesterol (p 0.001), HDL-cholesterol (p<0.01), osmolarity (p<0.001), and FBS (p 0.001) was observed in diet recipients. Following the intervention, there was a significant decrease in triglyceride (intervention group, p<0.05; control group, p<0.05), in both groups.
Conclusion: This trial showed that the plant–based food used in this study could improve blood rheology.- انتشار مقاله: 23-05-1396
- نویسندگان: Hamideh Naghedi Baghdar,Mohsen Nematy,Mohammad-Mahdi Kooshyar,Ali Taghipour,Sayyed Abolghasem Sajadi Tabassi,Sadegh Shokri,Roghayeh Javan,Seyed Mohammad Nazari
- مشاهده
- جایگاه : پژوهشی
- مجله: Avicenna Journal of Phytomedicine
- نوع مقاله: Journal Article
- کلمات کلیدی: Appetite,ghrelin,Food intake,Achillea Millefoliu,Hydroalcoholic extract
- چکیده:
- چکیده انگلیسی:
Objective: Achillea millefolium (A. millefolium) is known as an orexigenic herb in Iranian traditional medicine. In this study, the possible orexigenic effect of hydro-alcoholic extract of A. millefolium was investigated by measuring plasma ghrelin level.
Materials and Methods: Thirty male Wistar rats were divided into five groups. Control group received water. Treatment groups received 50, 100 or 150 mg/kg of A. millefolium extract for 7 days via gavage. Before the intervention, daily amount of the food eaten by each rat was measured for 10 days. During the investigation, the amount of energy intake of each rat was also estimated 1, 2, 4, 6 and 24 hr after each intake, for 7 days. Later, the orexigenic dose of extract and distilled water was fed to two separate groups of 6 male Wistar rats. Plasma ghrelin level was measured 0.5, 1, 2 and 4 hr after extract intake.
Results: The change in energy intake after treatment by 50 and 100 mg/kg of the extract was significantly higher than other groups (p<0.001). Administration of Achillea 100mg/kg significantly (p<0.05) decreased ghrelin level one hr after intervention but there was no significant (p>0.05) difference among control and treated group.
Conclusion: This study indicated that A. millefolium had positive dose-related effects on appetite in rats. It seems that the orexigenic activity of extract was not related to changes in plasma ghrelin levels.- انتشار مقاله: 29-02-1394
- نویسندگان: Mohsen Nematy,Mohsen Mazidi,Atefeh Jafari,Sara Baghban,Hasan Rakhshandeh,Abdolreza Norouzy,Habibollah Esmaily,Leila Etemad,Michael Patterson,Amir Houshang Mohammadpour
- مشاهده