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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Journal of Kerman University of Medical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: Biofilm,antimicrobial effect,Drug Resistant,Eucalyptus camaldulensis
- چکیده:
- چکیده انگلیسی: Background & Aims: Microorganisms are protected from antimicrobial agents when placed in biofilm structure. Biofilm-producing microorganisms are responsible for many problems in industry and medicine; therefore, it is essential to find new techniques for removing and inhibiting biofilms. This study aimed to examine the antimicrobial effect of Eucalyptus camaldulensis alcoholic extracts against planktonic form and biofilm of six bacteria including Staphylococcusaureus aureus, Bacillus cereus, Streptococcus pneumoniae, Pseudomonas aeruginosa, Escherichia coli, and Klebsiella pneumoniae. Methods: Antimicrobial activities of the plant extracts against the planktonic form of bacteria were evaluated using disc diffusion method. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values were determined using a macrobroth dilution technique. Anti-biofilm effects were assessed using microtiter plate method. Results: The results of this study confirmed the strong ability of E. camaldulensis extracts against the biofilm of tested bacteria and their free-living forms. Ethanolic extracts were more effective in inhibiting planktonic bacterial growth than methanolic extracts. Anti-biofilm effects of plant extracts were associated with the solvent and extract concentration. Eucalyptus camaldulensis methanol extract of 20 mg/ml concentration was the most efficient in the inhibition of biofilm formation of Staphylococcus aureus (84.42%). These extracts had the ability to remove more than 50% of stabilized biofilms. In Klebsiella pneumonia, however, only a 29.20% eradication of biofilms was observed. The highest decrease in methabolic activity was observed in Streptococcus pneumoniae biofilms (82.13%) treated with 20 mg/ml ethanolic extract. Conclusion: In this study, the antimicrobial activity of Eucalyptus camaldulensis extracts against the selected microorganisms was demonstrated. Thus, these extracts are recommended as a suitable option against the selected isolates
- انتشار مقاله: 24-04-1395
- نویسندگان: Zeynab Mohsenipour,Mehdi Hassanshahian,Mohammad Moradi
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Energy Management and Technology
- نوع مقاله: Journal Article
- کلمات کلیدی: Combined Heat and Power System,non-convex optimization,intelligent search algorithm
- چکیده:
- چکیده انگلیسی: Combined heat and power (CHP) systems have been utilized more and more in power systems, recently. With the increasing penetration of CHP-based co-generation of electricity
and heat, determination of economic dispatch of power and heat becomes a more complex
and challenging task. In this paper, the optimal operation of CHP-based system is studied and an algorithm is proposed for solution of it. The optimal operation of CHP-based
systems or CHP economic dispatch is inherently a nonlinear and non-convex optimization
problem with a lot of local optimal solutions. In this paper, frog leaping algorithm is used
for solution of the problem. This heuristic algorithm is well capable to attain the optimal
solutions even in the case of non-convex optimization problems. The proposed method is
implemented on several standard test systems. The obtained results have been compared
with other intelligent search algorithms. The numerical simulations verify that optimal
operation of CHP systems can result in a large economic annual saving.- انتشار مقاله: 17-03-1396
- نویسندگان: Abbas Rabiee,Mohammad Moradi-dalvand
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Herbal Drugs
- نوع مقاله: Journal Article
- کلمات کلیدی: WOUND HEALING,Biarum straussii,Phytomedicine,Rhizome extract
- چکیده: Background & Aim:Phytomedicine or herbal medicine, refers to the use of plants to treat diseases and promote good health. Anti-oxidative and anti-inflammatory characteristics of the medicinal herbs make them logical adjuvant to improve wound healing. The aim of this study was to evaluate the wound healing potential of Biarum straussiis’ (B. straussii) rhizome extract on cutaneous wounds in rats.
Experimental: Adult male rats (n=18) were divided into three groups (n=6), as group A, B and C. Then, full-thickness, square shape cutaneous wounds were created on the skin. In group A, as negative control, the wound area was only washed using normal saline solution; in group B as positive control, the wound was treated using phenytoin and the wound treatment using B. straussii rhizome extract was done in group C, as experimental subject. The progressive changes in wounds of each group were evaluated for the contraction degree on days 4,7,10 and 14. The tissue samples of the wound area were removed from each group on day 14, fixed in 10% formalin and finally stained with H&E for histological examination. Data analysis was carried out using one-way ANOVA test, followed by Tukey-Kramer test (p < /em><0.05).
Results: The wound contraction was higher in group treated with B. straussii extractthan in control group at 7th, 10th and 14th days (p < /em><0.0001). The histological analysis showed a significant accelerated wound contraction, complete re-epithelialization, and tissue recovery due to the topical application of B. straussii rhizome extract.
Recommended applications/ industries: It can be concluded that the rhizome extract of B. straussii is favorable for cutaneous wound healing in rats and would be considered as a medicinal plant, but further studies are required to reach more definitive results.- چکیده انگلیسی: Background & Aim:Phytomedicine or herbal medicine, refers to the use of plants to treat diseases and promote good health. Anti-oxidative and anti-inflammatory characteristics of the medicinal herbs make them logical adjuvant to improve wound healing. The aim of this study was to evaluate the wound healing potential of Biarum straussiis’ (B. straussii) rhizome extract on cutaneous wounds in rats.
Experimental: Adult male rats (n=18) were divided into three groups (n=6), as group A, B and C. Then, full-thickness, square shape cutaneous wounds were created on the skin. In group A, as negative control, the wound area was only washed using normal saline solution; in group B as positive control, the wound was treated using phenytoin and the wound treatment using B. straussii rhizome extract was done in group C, as experimental subject. The progressive changes in wounds of each group were evaluated for the contraction degree on days 4,7,10 and 14. The tissue samples of the wound area were removed from each group on day 14, fixed in 10% formalin and finally stained with H&E for histological examination. Data analysis was carried out using one-way ANOVA test, followed by Tukey-Kramer test (p <0.05).
Results: The wound contraction was higher in group treated with B. straussii extractthan in control group at 7th, 10th and 14th days (p <0.0001). The histological analysis showed a significant accelerated wound contraction, complete re-epithelialization, and tissue recovery due to the topical application of B. straussii rhizome extract.
Recommended applications/ industries: It can be concluded that the rhizome extract of B. straussii is favorable for cutaneous wound healing in rats and would be considered as a medicinal plant, but further studies are required to reach more definitive results.- انتشار مقاله: 08-04-1399
- نویسندگان: Sahar Ekradi,Tahereh Momeni- Isfahani,Mohammad Alimoradi,Masoumeh Khanahmadi
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Chemical Health Risks
- نوع مقاله: Journal Article
- کلمات کلیدی: Biocontrol,Aflatoxin,Competitiveness,Thin layer chromatography,Cultural methods,Ammonium hydrox-ide
- چکیده:
- چکیده انگلیسی: Application of atoxigenic strains of Aspergillus flavus to reduce aflatoxin levels is the most successful strategy applied in some agricultural crops. The role of ammonium hydroxide for preliminary screening of the competitiveness of atoxigenic A. flavus isolates to interfere with aflatoxin production by highly toxigenic isolates were evaluated. Out of 270 A. flavus isolates, 17 were detected as true atoxigenic using cultural methods and confirmed by analytical assays from different pistachio agro-ecological zones during 2013. For assessment competitive ability among atoxigenic isolates of A. flavus with highly toxigenic one, rice flour, coconut agar and coconut broth medium substrates were inoculated with mixtures including combinations of toxigenic and atoxigenic isolates, simultaneously. The rice flour substrate was used to quantify the content of aflatoxin in either co-inoculations or toxigenic isolate alone on thin layer chromatography plates with a scanning densitometer. While the culture media were used to determine the intensity of color change on exposing to ammonium hydroxide vapor. The reduction rates of aflatoxin B1 in co-inoculations were varied and ranged from 2%-82%. Based on the intensity of colony color changes, the competitiveness of the isolates was classified into five groups. Atoxigenic isolates with high competitiveness have shown low color changes in culture media and high aflatoxin reduction in TLC assays with a ratio of higher than 78%. The method will facilitate preliminary screening of efficient atoxigenic isolates for mitigation of aflatoxins in food and feed as a cheap, simple and quick method.
- انتشار مقاله: 06-02-1396
- نویسندگان: Mohammad Moradi,Seyed Reza Fani,Rosa Dargahi,Mehdi Mohammadi Moghadam,Abdolhamid Sherafati
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Advances in Environmental Health Research
- نوع مقاله: Journal Article
- کلمات کلیدی: Phenol,Photocatalytic process,aqueous solution,aluminum oxide,Persulfateoxidation
- چکیده:
- چکیده انگلیسی: The combination process of UV/ S2O82-/Al2O3 leads to the production of radicals and radical hydroxyls, which could decompose and remove various pollutants, such as phenol. The present study aimed to investigate the photocatalytic efficiency of aluminum oxide nanoparticles and persulfate compilative processes in the removal of phenol. This experimental study was conducted in a discontinuous reaction chamber with a useful volume of one liter. In this process, we assessed the effects of the initial pH parameters (3, 5, 7, and 9), initial concentration of phenol (10, 20, 30, 50, and 100 mg/l), concentration of persulfate anions (20, 30, 40, 50, and 60 mg/l), reaction time (5 and 120 minutes), and dose of Al2O3 nanoparticles (10, 20, 30, and 40 mg/l). The applied pilot was composed of a low-pressure mercury lamp (55 Watt), which was inside the steel chamber. The obtained data were fitted to the pseudo-first- and pseudo-second-order reaction kinetics. According to the findings, the process had high efficiency in the removal of phenol. In optimal conditions (pH:5, persulfate concentration: 50 mg/l, nanoparticle dose: 40 mg/l, reaction time: 60 minutes), the efficiency of the process was determined to be 95% at the initial phenol concentration of 10 mg/l, which was fitted with first-rate kinetics (R2=0.98). Furthermore, the highest efficiency was observed in the photocatalytic process of aluminum oxide nanoparticles and persulfates in the optimal conditions of exploitation. Therefore, persulfate could be used as an appropriate oxidizer with aluminum oxide nanoparticles for the removal of phenol.
- انتشار مقاله: 26-04-1397
- نویسندگان: Reza Shokoohi,Abdollah Dargahi,Ghobad Ahmadidoost,Mohammad Jamil Moradi
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Advances in Environmental Health Research
- نوع مقاله: Journal Article
- کلمات کلیدی: Phenol,Photocatalytic process,aqueous solution,aluminum oxide,Persulfateoxidation
- چکیده:
- چکیده انگلیسی: The combination process of UV/ S2O82-/Al2O3 leads to the production of radicals and radical hydroxyls, which could decompose and remove various pollutants, such as phenol. The present study aimed to investigate the photocatalytic efficiency of aluminum oxide nanoparticles and persulfate compilative processes in the removal of phenol. This experimental study was conducted in a discontinuous reaction chamber with a useful volume of one liter. In this process, we assessed the effects of the initial pH parameters (3, 5, 7, and 9), initial concentration of phenol (10, 20, 30, 50, and 100 mg/l), concentration of persulfate anions (20, 30, 40, 50, and 60 mg/l), reaction time (5 and 120 minutes), and dose of Al2O3 nanoparticles (10, 20, 30, and 40 mg/l). The applied pilot was composed of a low-pressure mercury lamp (55 Watt), which was inside the steel chamber. The obtained data were fitted to the pseudo-first- and pseudo-second-order reaction kinetics. According to the findings, the process had high efficiency in the removal of phenol. In optimal conditions (pH:5, persulfate concentration: 50 mg/l, nanoparticle dose: 40 mg/l, reaction time: 60 minutes), the efficiency of the process was determined to be 95% at the initial phenol concentration of 10 mg/l, which was fitted with first-rate kinetics (R2=0.98). Furthermore, the highest efficiency was observed in the photocatalytic process of aluminum oxide nanoparticles and persulfates in the optimal conditions of exploitation. Therefore, persulfate could be used as an appropriate oxidizer with aluminum oxide nanoparticles for the removal of phenol.
- انتشار مقاله: 26-04-1397
- نویسندگان: Reza Shokoohi,Abdollah Dargahi,Ghobad Ahmadidoost,Mohammad Jamil Moradi
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Basic and Clinical Pathophysiology
- نوع مقاله: Journal Article
- کلمات کلیدی: NICU,Newborn,Murmur,Congenital Heart Disease Echocardiography
- چکیده:
- چکیده انگلیسی: Background and Objective: Congenital heart disease (CHD) is the most form of cardiovascular disease in children. CHD have different presentations, from defects that progress asymptomatically to those with significant symptoms and high mortality. This study was performed to highlight the importance of signs and symptoms to diagnosis of CHD neonates. Materials & Methods: This descriptive analytic study was performed on 113 newborns in NICU ward of Mostafa Khomeini hospital from March 2010 to March 2011, referred for cardiac evaluation by echocardiography. Data and echocardiography results were extracted from patients’ documents. PDA in preterm newborns was excluded. Results: Echocardiographic findings were normal in 20 newborns and abnormal in 93 cases. Murmur and cyanosis were reasons for referral to cardiologist in 45 (39.82%) newborns, of which 42 (93.33%) newborns had CHD. DM in mothers was the reason for referral in 21 (18.85%) newborns, of which 17 (80.95%) newborns had CHD. Asphyxia was the reason for referral in 17 (15.04%) newborns, of which 14 (82.35%) newborns had CHD. Bradycardia was the reason for referral in 13 (11.50%) newborns, of which 11 (84.62%) newborns had CHD. Arrhythmia, associated congenital malformation, chromosome disorders, tachycardia, RDS and CHF were uncommon reasons for referral. Conclusion: The main reasons for referral were heart murmur and cyanosis. Although other reasons were uncommon, their presence indicated a high probability of diagnosis of heart disease.
- انتشار مقاله: 26-03-1393
- نویسندگان: Fatemeh Haji Ebrahim Tehrani,Hajieh Borna,Masoume Bazzaz,Shiva Rafati,Mohammad Moradi
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Artificial Intelligence in Electrical Engineering
- نوع مقاله: Journal Article
- کلمات کلیدی: PSO,PID,single-arm robot,reduction of coefficients
- چکیده:
- چکیده انگلیسی: This study on the design of PID controllers for flexible single-arm robot system optimization
PSO method is focused so that the coefficients of the PID controller are reduced. In this study,
PID controller and PSO algorithm have been described and then by using MATLAB, PID
control was simulated. Then by PSO algorithm, attempts to reduce the PID coefficients are given
by simulation. Finally PID coefficients' values were compared with and without the PSO
algorithm. The results showed that by using the number of birds and birds number steps, both
equal to 30 (the sixth), the lowest values of the coefficients p K , d K , i K are 0.741, 0.1491and
0, respectively.- انتشار مقاله: 07-09-1394
- نویسندگان: Mohammad Mehdi Moradi,Mohammad Mehdi Moradi,
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Pathology
- نوع مقاله: Journal Article
- کلمات کلیدی: Breast cancer,Metastasis,Polymorphism,thymidylate synthase,Methionine synthase,Methionine synthase reductase
- چکیده:
- چکیده انگلیسی: Background & Objective: Breast cancer (BC) is known to be the most prevalent cancer among women. One-carbon metabolism (OCM) disturbance might play an important role in the etiology of BC. The present study aimed to investigate the thymidylate synthase (TYMS), 5-methyltetrahydrofolate-homocysteine methyltransferase (MTR), and methionine synthase reductase (MTRR) variants as good candidates for studying the role of genetic variants of folate metabolizing enzymes in the risk of BC.
Methods: The present case-control study consisted of 100 BC patients and 141 healthy females. The TYMS 2R/3R (rs34743033), MTR c.2756A>G (rs1805087), and MTRR c.66A>G (rs1801394) variants were detected by polymerase chain reaction (PCR), PCR-restriction fragment length polymorphism (RFLP), and a designed amplification-refractory mutation system (ARMS) method, respectively.
Results: The 3R allele of TYMS enhanced the risk of BC by 2.84-fold (p <0.001). In the presence of TYMS 3R/3R, compared to TYMS 2R/3R, there was a trend toward enhancing the risk of metastasis by 4.15-fold (95% CI: 0.96-17.85, p =0.055). The frequencies of MTR c.2756A>G and MTRR c.66A>G variants were not significantly different among patients and controls.
Conclusion: We observed that the TYMS 3R is a risk allele for susceptibility to BC and this allele tends to increase the BC metastasis.- انتشار مقاله: 11-09-1398
- نویسندگان: Zohreh Rahimi,Maryam Bozorgi Zarini Bozorgi Zarini,Ziba Rahimi,Ebrahim Shakiba,Asad Vaisi-Raygani,Mohammad Taher Moradi,Kheirolah Yari
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Pathology
- نوع مقاله: Journal Article
- کلمات کلیدی: Antibiotics,Antibiogram,Resistance,Neonatal sepsis
- چکیده:
- چکیده انگلیسی: Background & Objective: Neonatal sepsis is one of the leading causes of mortality in neonatology wards. The aim of this study was to assess sepsis pathogens and antibacterial resistance patterns in a teaching hospital during seven years in Tehran, Iran.
Methods: In this retrospective study, all neonates suspected to sepsis and fulfilling the sepsis criteria admitted to NICU ward of Mustafa Khomeini Hospital, Tehran, Iran during 2007 to 2014 were included. Demographic information, blood test results, blood culture results of neonates and antibiogram findings were extracted from their documents. Data was analyzed using SPSS 15.
Results:Ninety neonates with positive culture test were included. Fifty-three were male (58.9%). Thirty neonates were delivered vaginally (33.3%) and 60 caesarean section (66.7%). Most bacterial growths in culture were Staphylococcus aureus and E. coli. The rates of resistance for antibiotics like ceftriaxone, cefotaxim and gentamycin were 5%, 30% and 15%, correspondingly. There were 15 cases (16.7%) with resistance to imipenem.
Conclusion: Antibacterial resistance patterns vary in different parts of the world and even within a country, therefore assessing resistance patterns in a region is of great importance for proper management and treatment. Our findings might help physicians for proper selection of antibiotics for treatment of neonatal sepsis.- انتشار مقاله: 21-05-1394
- نویسندگان: Fatemeh Haj Ebrahim Tehrani,Mohammad Moradi,Narjes Ghorbani
- مشاهده