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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Journal of the Iranian Chemical Research
- نوع مقاله: Journal Article
- کلمات کلیدی: Microwave Irradiation,Oxidation,Coupling,Thiol,Tripropylammonium fluorochromate,Disulfide
- چکیده:
- چکیده انگلیسی: Tripropylammonium fluorochromate(VI) (TPAFC), is an efficient and new reagent, which is
prepared easily and oxidizes thiols to the corresponding disulfides, quickly. The reactions are
performed cleanly and are controlled to stop at the disulfide stage, without over-oxidation and
side products. Coupling of thiols to their corresponding disulfides, are studied in solution at
room temperature and in solution under microwave radiation. The easy procedure, simple workup,
short reaction times, and excellent yields, are another advantages of this reagent.- انتشار مقاله: 11-05-1389
- نویسندگان: Mohammad Kazem Mohammadi,Neda Hasanzadeh,Shahriare Ghammamy
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Pharmaceutical and Health Sciences (JPHS)
- نوع مقاله: Journal Article
- کلمات کلیدی: Stroke,Ischemia-reperfusion,edema,Infarction,Keywords: Fullerene
- چکیده:
- چکیده انگلیسی: Aim: Oxidative stress plays a crucial role in the pathophysiology of ischemic stroke. Since water-soluble
fullerene derivatives act as the potent scavenger of oxygen free radicals in biological systems, we aimed
to investigate the possible protective effects of fullerol nanoparticles on brain infarction and edema in
transient model of focal cerebral ischemia in rat.
Materials & Methods: Experiment was performed by three groups of rats (each group; n=8): sham,
control ischemia (IR) and ischemia treated rats with fullerol. Brain ischemia was induced by 90 min
middle cerebral artery occlusion (MCAO) followed by 24 hours reperfusion. Treated rats received
fullerol at dose of 1 mg/kg 30 min before induction of MCAO. The brains were processed for histochemical
triphenyltetrazolium chloride (TTC) staining and quantitation of the ischemic infarct. Finally, the
brain hemispheres were weighed as an index of brain edema.
Results: MCAO induced brain infarction in large areas of cortex (261± 23 mm3) and subcortex (138±
23 mm3). Treatment with fullerol significantly reduced the infarct volume both in cortex and subcortex
by 64.75% and 52.17%, respectively. Induction of MCAO significantly increased the weights of right
hemispheres in IR group (0.77± 0.01 g) compared with sham rats (0.59± 0.01 g). Treatment with
fullerol decreased the weights of ischemic hemispheres in IR treated group (0.69± 0.03 g) compared to
IR non-treated rats.
Conclusion: Our findings indicate that fullerol nanoparticles are able to reduce the ischemia-induced
brain injury and edema possibly through their scavenging properties.- انتشار مقاله: 03-11-1394
- نویسندگان: Mahsa Sarami Foroshani,Mohammad Taghi Mohammadi
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Oral Health and Oral Epidemiology
- نوع مقاله: Journal Article
- کلمات کلیدی: Tissue engineering,Scaffold,Gingiva,Blood Platelet
- چکیده:
- چکیده انگلیسی: BACKGROUND AND AIM: An important goal of periodontal plastic surgery is the creation of attached gingiva around the teeth. In this study, the aims were to culture gingival fibroblasts in a biodegradable scaffold and measure the width of attached gingiva after the clinical procedure.METHODS: This study was carried out on 4 patients (8 sites), with inadequate attached gingiva next to at least two teeth in contralateral quadrants of the same jaw. A biopsy of attached gingiva (epithelial + connective tissue) was taken using a surgical blade. Following culture of gingival fibroblasts, 250 × 103 cells in 250 µl nutritional medium were mixed with platelet-rich in growth factor (PRGF). Periosteal fenestration technique was done on one side (control) and tissue-engineered mucosal graft (test) was carried out on the contralateral side in each patient. The width of keratinized tissue, probing depth (PD) and width of attached gingiva were recorded at baseline and 3 months after the operation.RESULTS: An increased width of keratinized and attached tissue on all operated sites after 3 months was observed. These results showed the increased mean of the width of keratinized and attached gingiva to be 4.17 mm and 4.14 mm in test and 1.10 mm and 1.10 mm in control sites, respectively. The difference of keratinized and attached gingiva width between test and control sites was significant (P = 0.030, and P = 0.010 respectively).CONCLUSION: According to the results of this study, PRGF can be used as a scaffold to transfer gingival fibroblasts to recipient sites with significant clinical results.
- انتشار مقاله: 07-09-1396
- نویسندگان: Moien Aramoon,Saeed Rajabalian,Mohammad Mohammadi,Neda Khodarahmi,Maryam Farzadmoghadam
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Oral Health and Oral Epidemiology
- نوع مقاله: Journal Article
- کلمات کلیدی: Surgery,Gingiva,Denudation
- چکیده:
- چکیده انگلیسی: BACKGROUND AND AIM: The present study was performed in order to assess the effect of gingival thickness on amount of gingival augmentation with and without preserving periosteum.METHODS: The study was conducted on 8 ecotype dogs aged 1-5 years. At the beginning, clinical probing depth and keratinized and attached gingiva width were measured. Totally, 64 sites were operated in this study. Periosteal fenestration and denuded beds were randomly created on opposite sides of upper and lower jaws (4 sites each side). The thickness of gingiva was measured in mucogingival junction after preparation of the beds. The clinical parameters were evaluated 2 months after the surgery. The data were analyzed by Mann-Whitney U, Wilcoxon, and Pearson correlation tests.RESULTS: The results showed the average increased width of keratinized and attached gingiva was 1.8 mm and 2 mm in periosteal fenestration sites and 1.9 mm and 2.3 mm in denudation sites, respectively at 2 months post-surgery. The difference between the width of keratinized gingiva and attached gingiva before and 2 months after operation was significant in both groups (P < 0.001). However, no significant difference was shown between the two groups in terms of attached and keratinized gingival width (P = 0.100 and P = 0.720, respectively). There was no correlation between the thickness of gingiva and the amount of increased width of keratinized and attached gingiva.CONCLUSION: A gingival thickness of 0.8 to 2 mm does not affect the increment of the attached and keratinized gingival width with and without preserving periosteum.
- انتشار مقاله: 16-03-1396
- نویسندگان: Saeedeh Ebrahimi,Jalil Abshenas,Mohammad Mehdi Molaei,Mohammad Mohammadi,Nastaran Karimi
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Oral Health and Oral Epidemiology
- نوع مقاله: Journal Article
- کلمات کلیدی: Periodontitis,Immunoglobulin A,Major thalassemia
- چکیده:
- چکیده انگلیسی: BACKGROUND AND AIM: This study was conducted to evaluate salivary immunoglobulin A (IgA) level in thalassemic patients with periodontitis in comparison to thalassemic patients with healthy periodontium.METHODS: Seventy-five patients were included in this study and were divided into three groups, group A: 25 major thalassemic patients with mild to moderate periodontitis, group B: 25 thalassemic patients with healthy periodontium, and group C: 25 systemically healthy people with normal periodontium. To measure salivary IgA levels, stimulated saliva was collected and analyzed by enzyme-linked immunosorbent assay (ELISA). The data were analyzed by t-test, ANOVA, and chi-square.RESULTS: Salivary IgA was significantly different in major thalassemia patients with periodontitis (69 µm/ml) in comparison to major thalassemia patients with healthy periodontium (81 µm/ml) (P < 0.05). The highest level of salivary IgA was observed in the systemically healthy people with normal periodontium (88 µm/ml).CONCLUSION: The levels of salivary IgA were decreased in major thalassemia patients with periodontitis and healthy periodontium in comparison to systemically healthy people with normal periodontium.
- انتشار مقاله: 07-10-1395
- نویسندگان: Mohadeseh Arabsolghar,Parvin Arbabi,Mohammad Mohammadi,Alireza Farsineja
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Oral Health and Oral Epidemiology
- نوع مقاله: Journal Article
- کلمات کلیدی: Tooth Brushing,Dental Plaque Index,Bleeding Point Index
- چکیده:
- چکیده انگلیسی: BACKGROUND AND AIM: The mechanical removal of plaque by tooth brushing is the most effective way for prevention of caries and periodontal diseases. Some studies indicate that the design and shape of toothbrush could be the effective for this point. The aim of this study was to compare the efficacy of a Classic toothbrush with a Superbrush toothbrush in controlling plaque and gingival bleeding over a 2-week period of brushing.METHODS: This study was a crossover clinical trial, involving 30 healthy individuals who were dental students of both sexes, randomly divided equally into two groups with simple method: group A (Classic Toothbrush; Soft, Tepe, Sweden) and group B (Superbrush Toothbrush; Soft, Dentaco AS, Haukeland, Norway). After taking an informed consent, the baseline O’Leary plaque index (PI) and bleeding point index (BPI) was recorded, and the subjects were given common toothpaste (Crest). A prophylaxis was performed to achieve the PI of zero and then the demonstration of Bass technique was given to each subject. Each group started the experiment with a different type of toothbrush for 1 week which followed by 1 week of wash-out. After that, each group switched to the next type of toothbrush for 1 week. All subjects had to refrain from other oral hygiene procedures for the duration of the study. The results were analyzed statistically by independent t-test and paired t-test. A statistical significance was set at the 95% confidence level (P < 0.050).RESULTS: Superbrush showed a significant reduction of both PI (P = 0.050, P < 0.050) and BPI (P = 0.001) at 7 and 14th days with respect to the baseline. The analysis revealed that the Superbrush was significantly a more effective in removing plaque as compared to the Classic toothbrush (P < 0.010), while according to the BPI, there were no statistically significant differences between the two brushes (P = 0.185, P > 0.050).CONCLUSION: The results showed the efficacy of Superbrush toothbrush in a significant reduction of PI and BPI, so it can be suggested to patients as an alternative to the Classic toothbrush.
- انتشار مقاله: 10-08-1394
- نویسندگان: Sasan Salahi,Fereshteh Moosaali,Mohammad Moradian-Mohammadieh
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Oral Health and Oral Epidemiology
- نوع مقاله: Journal Article
- کلمات کلیدی: Phenytoin,gingival recession,Creeping Attachment
- چکیده:
- چکیده انگلیسی: BACKGROUND AND AIM: The aim of this study was to evaluate the effect of topical phenytoin on creeping attachment. METHODS: In this pilot quasi-experimental study, 8 patients referring to Kerman School of Dentistry, Kerman, Iran with Miller class I or II gingival recessions were selected using convenient non-random sampling if they needed root coverage and met the study's inclusion criteria. The patients applied phenytoin mucoadhesive paste 1% on the surface of the deepithelialized gingiva of the tooth with gingival recession, twice a day for two months. Data was analyzed with paired t-test using SPSS version 17. RESULTS: According to our findings, the width of keratinized gingiva at the baseline was 3 mm, and after 2 months it increased to 3.1 mm. The mean baseline height and width of gingival recession were 1.9 mm and 3 mm, respectively, and after 2 months they decreased to 1.8 mm and 2.9 mm accordingly. There was no significant difference in any of the aforementioned parameters before and after treatment (P > 0.05). CONCLUSIONS: The results of this study showed that topical application of phenytoin mucoadhesive paste can not initiate and promote creeping attachment.
- انتشار مقاله: 09-11-1391
- نویسندگان: Gholam Ali Najafi-Parizi,Mohammad Mohammadi,Mohammad Seifsafari
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Oral Health and Oral Epidemiology
- نوع مقاله: Journal Article
- کلمات کلیدی: menstrual cycle,Halitosis,ß-estradiol,volatile sulfur compound
- چکیده:
- چکیده انگلیسی: BACKGROUND: ß -estradiol is a steroid sex hormone that plays important role in oral physiology. The aim of this study was to determin the association of the menstrual cycle and salivary ß-estradiol with the production of volatile sulfur compounds (VSC).METHODS: In this cross-sectional study, twenty female dental students in good oral and general health were recruited for evaluation of VSC, salivary flow, ß-estradiol concentration, oral dryness feeling and dysmenorrhea. Data were analyzed by marginal homogeneity test and xtgee model.RESULTS: The only covariates that significantly related to VSC were being at the follicular phase (B = -0.21, P = 0.02), being at the pre-menstrual phase (B = -0.25, P = 0.01), stressfulness (B = 0.02, P = 0.01) and oral dryness feeling (B = 0.34, P = 0.02). Salivary ß-estradiol was at the level of 59.7 ± 31.2 in those having halitosis (VSC ≥ 75) while in the others (VSC < 75) it was about 40.8 ± 18.0 (P < 0.009). This difference was not statistically significant in multivariate analysis.CONCLUSIONS: The menstrual cycle, stress and oral dryness were the most important determinants of halitosis. The salivary ß-estradiol level could not explain such relationship as its effect was eliminated considering the other factors.
- انتشار مقاله: 13-04-1391
- نویسندگان: Shahla Kakoei,Fahimeh Barkhori,Ali Mirzazadeh,Mohammad Mohammadi,Ahmad Gholamhoseinian
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Oral Health and Oral Epidemiology
- نوع مقاله: Journal Article
- کلمات کلیدی: Graft materials,Dental implants,Guided bone regeneration,alveolar ridge augmentation
- چکیده:
- چکیده انگلیسی: Guided bone regeneration (GBR) is a reconstructive procedure of alveolar ridge using membranes. This procedure is indicated when there is no sufficient bone for implantation, or in the case of optimal implant installation for esthetic or functional needs. GBR can be performed before implant placement, when there is not enough bone for initial stability of implants and less predictable outcomes (staged approach), or performed simultaneously with implantation (combined approach). GBR techniques have been used for vertical and horizontal ridge augmentations with acceptable results. This literature review discusses the background, principles of GBR, the materials used in GBR (types of membranes and bone grafts), success criteria and long term results of GBR.
- انتشار مقاله: 13-04-1391
- نویسندگان: Maryam Farzad,Mohammad Mohammadi
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Optimization in Industrial Engineering
- نوع مقاله: Journal Article
- کلمات کلیدی: Water Cycle Algorithm,Linearization,Lot sizing,Distributed permutation flow shops,Monarch butterfly optimization
- چکیده:
- چکیده انگلیسی: This paper addresses a new mixed integer nonlinear and linear mathematical programming economic lot sizing and scheduling problem in distributed permutation flow shop problem with number of identical factories and machines. Different products must be distributed between the factories and then assignment of products to factories and sequencing of the products assigned to each factory has to be derived. The objective is to minimize the sum of setup costs, work-in-process inventory costs and finished products inventory costs per unit of time. Since the proposed model is NP-hard, an efficient Water Cycle Algorithm is proposed to solve the model. To justify proposed WCA, Monarch Butterfly Optimization (MBO), Genetic Algorithm (GA) and combination of GA and simplex are utilized. In order to determine the best value of algorithms parameters that result in a better solution, a fine-tuning procedure according to Response Surface Methodology is executed.
- انتشار مقاله: 03-06-1396
- نویسندگان: Mohammad Alaghebandha,Bahman Naderi,Mohammad Mohammadi
- مشاهده