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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Archives of Bone and Joint Surgery
- نوع مقاله: Journal Article
- کلمات کلیدی: Methylene blue,Fibrosis,Anterior Cruciate Ligament,Arthrofibrosis,Stifle
- چکیده:
- چکیده انگلیسی: Background: One of the major challenges in orthopedic surgery is the prevention of arthrofibrosis, which can be
successfully alleviated in its early stages. Many studies suggest the administration of methylene blue (MB) as an
accessible and effective agent for the prevention of post-operation adhesions. The purpose of this study was to evaluate
the efficacy of MB in the prevention of arthrofibrosis.
Methods: This study was conducted on 18 New Zealand white female mature rabbits. The anterior cruciate ligament
of the left stifle joint of each animal was cut during aseptic surgery. In the next step, the rabbits were divided into three
groups based on their treatments. The rabbits in the first, second, and third groups were subjected to the injection of
normal saline, 1% MB solution, and 2% MB solution into their synovial space, respectively. The postoperative stifle
range of motion was measured every week. After 4 weeks, the animals were euthanized and all joints were dissected
for histopathology.
Results: The histopathological evaluation of tissues indicated the presence of fibrotic connective tissue as a sign of
fibrosis in all groups. The fibrosis rate, inflammatory rate, tissue disarrangement, fibroblastic cellularity, and granulation
tissue formation were at their highest levels in the 1% MB group. The integrity of articular cartilage in the 2% MB group
was lower than the other groups. The level of bone degeneration was similar in both MB groups; however, it was more
than the control saline group. The range of motion was reduced during the first week, then increased in the second and
third weeks, and finally decreased in the fourth week.
Conclusion: The MB was not an effective method regarding the prevention or treatment of arthofibrosis and the
subsequent osteoarthritis. In contrast with previous studies, fibrosis was lower in the high dose MB group, compared
to the low dose MB group. The alterations in the range of motion were related to the reduced movement caused by the
pain and stiffness of the operated joints. The current study can be considered as the first report addressing the adverse
effect of MB on synovial components.- انتشار مقاله: 21-05-1396
- نویسندگان: Hamid Namazi,Mohammad J. Emami,Fatemeh Dehghani Nazhvani,Ali Dehghani Nazhvani,Zeinab Kargarshouroki
- مشاهده
- جایگاه : پژوهشی
- مجله: Archives of Bone and Joint Surgery
- نوع مقاله: Journal Article
- کلمات کلیدی: Methylene blue,Fibrosis,Anterior Cruciate Ligament,Arthrofibrosis,Stifle
- چکیده:
- چکیده انگلیسی: Background: One of the major challenges in orthopedic surgery is the prevention of arthrofibrosis, which can be
successfully alleviated in its early stages. Many studies suggest the administration of methylene blue (MB) as an
accessible and effective agent for the prevention of post-operation adhesions. The purpose of this study was to evaluate
the efficacy of MB in the prevention of arthrofibrosis.
Methods: This study was conducted on 18 New Zealand white female mature rabbits. The anterior cruciate ligament
of the left stifle joint of each animal was cut during aseptic surgery. In the next step, the rabbits were divided into three
groups based on their treatments. The rabbits in the first, second, and third groups were subjected to the injection of
normal saline, 1% MB solution, and 2% MB solution into their synovial space, respectively. The postoperative stifle
range of motion was measured every week. After 4 weeks, the animals were euthanized and all joints were dissected
for histopathology.
Results: The histopathological evaluation of tissues indicated the presence of fibrotic connective tissue as a sign of
fibrosis in all groups. The fibrosis rate, inflammatory rate, tissue disarrangement, fibroblastic cellularity, and granulation
tissue formation were at their highest levels in the 1% MB group. The integrity of articular cartilage in the 2% MB group
was lower than the other groups. The level of bone degeneration was similar in both MB groups; however, it was more
than the control saline group. The range of motion was reduced during the first week, then increased in the second and
third weeks, and finally decreased in the fourth week.
Conclusion: The MB was not an effective method regarding the prevention or treatment of arthofibrosis and the
subsequent osteoarthritis. In contrast with previous studies, fibrosis was lower in the high dose MB group, compared
to the low dose MB group. The alterations in the range of motion were related to the reduced movement caused by the
pain and stiffness of the operated joints. The current study can be considered as the first report addressing the adverse
effect of MB on synovial components.- انتشار مقاله: 21-05-1396
- نویسندگان: Hamid Namazi,Mohammad J. Emami,Fatemeh Dehghani Nazhvani,Ali Dehghani Nazhvani,Zeinab Kargarshouroki
- مشاهده
- جایگاه : پژوهشی
- مجله: Archives of Bone and Joint Surgery
- نوع مقاله: Journal Article
- کلمات کلیدی: Achilles tendon,Wound complication,Open repair
- چکیده:
- چکیده انگلیسی:
Background: Wound complications following open repair for acute Achilles tendon ruptures (AATR) remain the subject of
significant debate. The aim of this study is to investigate the effects of covering repaired AATR using well-nourished connective tissues (paratenon and deep fascia) to avoid complications after open repair.
Methods:
In this case series study, open repair was performed for 32 active young patients with AATR. After the tendon was repaired, the deep fascia and paratenon was used to cover the Achilles tendon. Patients were followed for two years and any wound complication was recorded. During the last visit, the American Orthopedic Foot and Ankle Society (AOFAS) ankle-hind foot score was completed for all patients. Calf circumference and ankle range of motion were measured and compared with the contralateral side. Patients were asked about returning to previous sports activities and limitations with footwear.
Results:
Only, one patient developed deep wound infection (3%). None of the patients had any discomfort around the operation area, limitation with footwear, sural nerve injury, re-rupture, and skin adhesion. The AOFAS score averaged 92.5±6. Two patients (7%) were unable to return to previous sports activities because of moderate pain in heavy physical exercises. The calf circumference and ankle ROM were similar between healthy and operated sides.
Conclusion:
The present study showed that fascial envelope for full covering of the repaired Achilles tendon may help to prevent the occurrence of wound complications.- انتشار مقاله: 12-06-1392
- نویسندگان: Sohrab Keyhani,Mohsen Mardani-Kivi,Mohammadreza Abbasian,Mohammad Emami Moghaddam Tehrani,Farivar Abdollahzadeh Lahiji
- مشاهده
- جایگاه : پژوهشی
- مجله: Archives of Bone and Joint Surgery
- نوع مقاله: Journal Article
- کلمات کلیدی: intertrochanteric fracture,Bipolar hemiarthroplasty,Dynamic hip screw
- چکیده:
- چکیده انگلیسی: Background: At present, there is no consensus on an appropriate treatment modality for intertrochanteric fractures in the elderly with background diseases. The aim of the present study was to compare treatment outcomes of intertrochanteric fractures reduced with dynamic hip screws (DHS) and bipolar hemiarthroplasty in elderly patients with background medical conditions.
Methods: In this randomized clinical trial, 60 patients with intertrochanteric fractures, who were 45-60 years old, were randomly divided into DHS and bipolar groups. After treatment, the two groups were compared in relation to complications and mortality rates, functional status using the Harris Hip Score (HHS), range of movement and severity of pain using the visual analogue score (VAS). Results: HHS (86±9 vs. 75±7.6), range of flexion (105±11 degrees vs. 90±17 degrees) and external rotation (35±7 degrees vs. 20±7 degrees) were significantly higher in the bipolar group compared to the DHS group (P<0.05). However, there were no significant differences in pain severity between the two groups.
Conclusion: Reduction of intertrochanteric fractures in elderly patients with background medical conditions is more effective and less problematic with the bipolar technique compared to DHS and is better tolerated by patients, because this technique is associated with improvements in functional status and hip joint movement range.- انتشار مقاله: 25-04-1392
- نویسندگان: Mohammad Emami,Ali Reza Manafi,Behroz Hashemi,Ali Nemati,Saeed Safari
- مشاهده
- جایگاه : پژوهشی
- مجله: Archives of Bone and Joint Surgery
- نوع مقاله: Journal Article
- کلمات کلیدی: Iran,knee,Hip,Arthroplasty,Registry national
- چکیده:
- چکیده انگلیسی:
Periodic evaluation and monitoring the health and economic outcome of joint replacement surgery is a common and popular process under the territory of joint registries in many countries. In this article we introduce the methodology used for the foundation of the National Iranian Joint Registry (IJR) with a joint collaboration of the Social Security Organization (SSO) and academic research departments considering the requirements of the Iran’s Ministry of Health and Education.
- انتشار مقاله: 14-11-1394
- نویسندگان: Hamidreza Aslani,Seyed Taghi Nourbakhsh,Farivar A Lahiji,Keykavoos Heydarian,Mahmood Jabalameli,Mohammad Taghi Ghazavi,Mahmoud Reza Fayyaz,Mohammad Ali Sazegari,Maziar Mohaddes,Mojtaba Rajabpour,Mohammad Emami,Seyyed Mohammad Jazayeri,Firooz Madadi,Hossein Farahini,Fardin Mirzatoloee,Mohammad Gharahdaghi,Mohammad Hossein Ebrahimzadeh,Mohammadreza Ebrahimian,Hossein Mirvakili,Kaveh Bashti,Mohtasham Almasizadeh,Mansour Abolghasemian,Afshin Taheriazam,Mehdi Motififard,Hamidreza Yazdi,Mahmood Karimi Mobarakeh,Masoud Shayestehazar,Mehdi Moghtadae,Babak Siavashi,Mohammadreza M Sajjadi,Alireza Manafi Rasi,Seyyed Kazem Chabok,Zohreh Zafarani,Shahin Salehi,Monireh Ahmadi,Amin Mohammadi,Mohammad Ebrahim Shahsavand
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Renewable Energy and Environment
- نوع مقاله: Journal Article
- کلمات کلیدی: Photovoltaics,Technical Analysis,Economic Analysis,Solar Energy,Energy Payback Time,BIPV
- چکیده:
- چکیده انگلیسی: The renewable energy can be utilized to satisfy the energy demand. Moreover, the solar energy as the most abundant energy resource among renewable energies plays a crucial role to provide the energy demand. The BIPV (building integrated photovoltaics) systems can be considered to supply the required energy demand from renewable sources. The essential advantage of BIPV systems is that they can be utilized as building component such as roof, window, shading systems and building façade and they can generate electricity simultaneously. Even though the photovoltaic technologies have been improved within past few years, however the utilization of the BIPV systems will be considered expensive. For this reason, the payback period calculation is considered a vital parameter in evaluating the BIPV systems. In this study, the overall energy consumption for producing one m2 of a mono-crystalline photovoltaic module is calculated 1334 kWh. Additionally, the photovoltaic module data for three companies were investigated and the annual energy productions for one m2 of each company’s product were obtained. The results showed that the average energy payback time for 270 and 280 watt modules are 5.565 and 5.254 respectively. Moreover, the energy payback time for 290, 325 and 340 watt modules were calculated 4.903, 5.437 and 4.965 respectively.
- انتشار مقاله: 19-05-1398
- نویسندگان: Seyed Mohammad Emami Razavi,Mohammad Hossein Jahangir,Soroush Mousavi
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Nutrition,Fasting and Health
- نوع مقاله: Journal Article
- کلمات کلیدی: ALT,fasting,Ramadan
- چکیده:
- چکیده انگلیسی: Introduction: The effects of Ramadan fasting on NAFLD are unknown and there are very limited studies have done in this area. Some nutritional and behavioral changes of fasting people in Ramadan can affect NAFLD. These include nutrition with high fat and calories, altering in weight and sleep and low physical activity. We decided to evaluate the effects of these changes on one of the important indicators of deterioration of NAFLD, ALT. Methods: Sixty patients with fatty liver disease performed two consecutive ALT exams before and after Ramadan month of whom finally 34 were fasting and 26 nonfasting. After collecting data they were divided in two groups of fasting and nonfasting and compared using SPSS software. Results: Mean ALT change from before to after Ramadan was higher and positive in fasting (+7.38±8.47 IU/L) compared to nonfastng patients that was negative (-0.12±10.15 IU/L) (P=0.002) and this change was mainly in patients who had fasted 21-30 days. Conclusion: Ramadan fasting may increase ALT. It is needed to perform more studies in patients with NAFLD during Ramadan fasting with larger sample size and in various conditions especially weight loss with patients’ education for observing dietary regimen.
- انتشار مقاله: 06-04-1396
- نویسندگان: Hojjatolah Rahimi,Mohammad Emad Habibi,Ali Gharavinia,Mohammad Hasan Emami,Abdolmahdi Baghaei,Najmeh Tavakol
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Veterinary Surgery
- نوع مقاله: Journal Article
- کلمات کلیدی: Dog,Amniotic membrane,corneal alkali burn,Dermabond®,2-Octyl cyanoacrylate
- چکیده:
- چکیده انگلیسی: Objective- This study was performed to evaluate and compare grossly and pathologically two surgical techniques of amniotic membrane patching on experimental corneal alkali burn in dogs. Design- Experimental study. Animals- Fifteen healthy dogs Procedures- The central corneas of the dogs were inflicted by applying a round filter paper, 6.0 mm in diameter, soaked in 1 N NaOH for 60 sec. A corneal alkali burn was made unilaterally in each dog's eye. A total of fifteen dogs were divided into three groups of five each: (A) uncovered as a control group; (B) covered by amniotic membrane (AM) patching with the amnion cell side down sutured around the corneal wound area with 10/0 nylon as AM+suture group; (C) covered by sutureless amniotic membrane patch adhered by 2-Octyl cyanoacrylate (Dermabond®) as AM+glue group. Time of surgery and AM persistence were recorded. After 3 weeks eyes enucleated and Samples were monitored by evaluating of most important pathological features. Results- The mean time of surgery in group B was significantly longer than group C. AM persistence in group C was significantly more than group B. Corneal thickness measurements and numbers of epithelial rows showed no significant statistical differences between different groups. Group C has had significant lower degree of corneal vascularization than group A. Stromal edema was most prominent in group A, but statistical analysis revealed no significant statistical differences between groups. Stromal collagen arrangement showed no significant differences. AM patched corneas (group B, C) show lower inflammation, compared with the uncovered one (group A). Among the AM patching groups, the group C revealed the best result. Conclusion and Clinical Relevance- use of the sutureless amniotic membrane patching with 2-Octyl cyanoacrylate as a dressing on a corneal alkali burn could induce rapid epithelial healing with less inflammatory response as well as reduce the time of operation in dogs.
- انتشار مقاله: 20-05-1392
- نویسندگان: Mohammad Abbaszadeh,Seyed Javid Aldavood,Alireza Foroutan,Seyed Hossein Mardjanmehr,Mohammad Azizzadeh,Mohammad Reza Emami,Sadra Izadi
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Veterinary Surgery
- نوع مقاله: Journal Article
- کلمات کلیدی: Dog,Ketamine,Anesthesia,Romifidin,Xylazin
- چکیده:
- چکیده انگلیسی: Objective: To compare romifidine and xylazine premedication in ketamine anesthesia of the dog. Design: Experimental design. Animals: Fifteen cross-breed dogs. Procedures: Animals randomly allocated into three groups of five. Group G1 premedicated by xylazine 1 mg/kg, G2 romifidine 40 µg/ kg and G3 romifidine 80 µg/ kg intramuscularly. All animals premedicated with atropine 0.02 mg/kg subcutaneously ten minutes before induction of anesthesia. Anesthesia was induced by 15 mg/kg ketamine IM. Heart rate, respiratory rate, mean arterial blood pressure and eclectrocardiac activity beside quality of anesthesia were evaluated. Results: No significant differences were found between three groups around all recorded parameters. Conclusions and Clinical relevance: Usage of different doses of romifidine in canine species is possible without any unexpected outcome, 80 µg/ kg of romifidine make better onset of anesthesia.
- انتشار مقاله: 28-05-1392
- نویسندگان: Mohammad Reza Emami,Mohammad Reza Sedighi,Shamsedin Sarhaddi
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Immunology
- نوع مقاله: Journal Article
- کلمات کلیدی: Celiac disease,Diagnosis, Gut, Intraepithelial Lymphocytes
- چکیده:
- چکیده انگلیسی: Background: Increased number of intestinal intraepithelial lymphocytes (IELs) is a key histological finding in the diagnosis of celiac disease (CD); however, the number of IELs in celiac patients and healthy subjects may vary from one region to another. Additionally, there are some seronegative celiac patients with a borderline histology. Objective: To determine the number of the CD3+ and CD8+ IELs T-cells in the celiac patients and healthy subjects (controls) in Isfahan. Methods: The duodenal biopsies were obtained from the celiac patients (n=15) and the controls (n=19). The total number of IELs/100 epithelial cells (ECs) were counted using the hematoxylin-eosin (H&E) staining method, and that of CD3+ and CD8+ IELs/100 ECs were counted using the immunohistochemistry (IHC) staining method. Results: This study defined the upper normal limit for each variable as mean + 2SD. Accordingly, the upper normal limits of the total IELs, CD3+ IELs, and CD8+ IELs/100 ECs were calculated as 37 (95% confidence intervals, CI: 33–41), 22 (95% CI: 19–25) and 12 (95% CI: 10–14), respectively. In 3 clinically CD diagnoses, the total IELs counts/100 ECs were below the upper normal limit, and the histopathological and serologic assays were negative. Nevertheless, the CD8+ IELs T-cells counts/100 ECs showed borderline values. Interestingly, these patients responded to a gluten-free diet (GFD). Conclusions: The study findings suggest that in the clinically diagnosed celiac disease, IELs count/100 ECs below the upper normal limit as well as negative histopathological and serologic assays and the cell density counts of the CD8+ IELs T-cells/100 ECs could be a useful parameter for CD diagnosis and make a decision to put them on a GFD.
- انتشار مقاله: 17-02-1397
- نویسندگان: Hadi Hossein-Nataj,Mohsen Masjedi,Mohammad Hassan Emami,Mojgan Mokhtari,Fereshteh Alsahebfosoul
- مشاهده