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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: Prostate cancer,Calcium,systematic review and meta-Analysis
- چکیده:
- چکیده انگلیسی: Background: Controversial results have been reported concerning the influence of calcium intake on prostate cancer
risk. The aim of this study was to determine any association between total calcium (in the diet and in supplements) intake
and prostate cancer. Materials and Methods: The present systematic review and meta-analysis study was carried out
following a PRISMA guidelines. Two reviewers independently using MeSH keywords searched international databases
including PubMed, Science Direct, Cochrane, EMBASE, Web of Science, CINAHL, EBSCO and search engines such
as Google Scholar. The searches were performed without any time limit until May 2016. The results were pooled
using a random effects model and homogeneity was confirmed using the Q test and I2 index. Subgroup analyses was
performed according to continents and study designs. The data were analyzed using STATA software version 3.2, with
pfinal meta-analysis. The main age range of the participants was 50 to 70 years. The relative risks (RR) for total calcium
with total prostate cancer, localized prostate cancer, and advance prostate cancer were estimated to be 1.15 (95% CI:
1.04-3.46), 1.05 (95% CI: 0.96-1.14), and 1.15 (95% CI: 0.89-1.50), respectively. Only the relationship between total
calcium and total prostate cancer was significant (P<0.05). Conclusions: High calcium intake can be considered as a
risk factor for total prostate cancer. Therefore, calcium intake might be a target for prevention.- انتشار مقاله: 04-07-1396
- نویسندگان: Shoboo Rahmati,Milad Azami,Ali Delpisheh,Mohammad Reza Hafezi Ahmadi,Koroush Sayehmiri
- مشاهده