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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Journal of Oral Health and Oral Epidemiology
- نوع مقاله: Journal Article
- کلمات کلیدی: head and neck cancer,Short Form-36 (SF-36),Oral Health Impact Profile-14 (OHIP-14)
- چکیده:
- چکیده انگلیسی: BACKGROUND: Head and neck cancer is one of the six most prevalent neoplasms worldwide. Regardless of tumor site, deterioration of basic functions affecting head and neck areas are perceived and affect patients' lives. The aim of this study was to evaluate quality of life (Short Form) and oral health related quality of life (OHIP-14) in patients with head and neck cancer. METHODS: This study was conducted on 42 patients being treated for head and neck cancer. Data collected from the survey included demographic (sex, age, and educational level), quality of life (QoL), and Oral Health Related Quality of Life (OHRQoL), which were, respectively, measured by short form-36 and OHIP-14 questionnaire. Cancer measurements were collected from the patient’s hospital records. ANOVA and t-tests were used to determine the association between QoL scores and the variables. RESULTS: 83.3% of the participants were men and 16.7% were women. Their mean age was 59.39 ± 12.5 years. 33.3% of the participants had oral cancer. 54.8% of patients had stage III cancer. The mean score of OHIP-14 was 21.4 ± 10.11. There was a significant correlation between OHIP-14 and site of cancer, and dose of radiation (P = 0.02 and P = 0.009, respectively). The best score of SF-36 was in social function (55.11 ± 30.9) and the worst score of SF-36 was in vitality domain (29.76 ± 9.67). There was a significant correlation between physical function, vitality and social activity with OHIP-14 (P = 0.02, P = 0.011, P = 0.009, respectively). CONCLUSIONS: The QoL scores in Kerman like the other studies were low. Head and neck cancer can have a negative impact on QoL. Further research is recommended.
- انتشار مقاله: 25-10-1391
- نویسندگان: Molouk Torabi,Mohammad Hasan Larizadeh,Hossein Safizadeh,Marzieh Karimi Afshar,Nader Modares Ahmadi
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Kerman University of Medical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: Iran,Radiotherapy,Larynx cancer,Survival rate SCC
- چکیده:
- چکیده انگلیسی: Background:The incidence rate of head and neck cancer in the world is about 560,000 new cases a year. Larynx cancer is the most common malignancy in head and neck in Iran. The most common head and neck carcinoma is the malignancy of squamous epithelial cells. This study was conducted to determine the survival rate of patients undergoing nonsurgical treatment methods for laryngeal squamous cell carcinoma in Kerman, Iran. Methods:This retrospective study was conducted on patients with squamous cell carcinoma of larynx following nonsurgical treatment, who were referred to a radiation therapy center in Kerman, Iran, from 2003 to 2015.The likelihood of survival of patients based on the age, sex, stage of disease, non-surgical treatment, laryngeal preservation, as well as survival without progression and recurrence of the disease was determined. Results:Mean age of the studied patients was 56.56 years. The patients had a mean survival rate of 52.92 months, mean disease free survival rate of 47.60 months and mean progression free survival rate of 11.29 months. The survival rate was higher in patients undergoing RT, followed by those undergoing CCRT and CT-RT (P<0.001). The patients had a one-year disease free survival rate of 69%, a three-year disease-free survival rate of 57% and a five-year disease-free survival rate of 44% and had a one-year progression free survival rate of 13% as well as a three- and a five-year progression free survival rate of 18%. Conclusion: Overall survival rate was significantly different based on the type of non-surgical treatment, gender and the stage of cancer.
- انتشار مقاله: 27-06-1398
- نویسندگان: Mohammad Hasan Larizadeh,Maryam Bahador,Reza Daneshfar,Mehdi Borhani Zarandi
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Kerman University of Medical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: Radiotherapy,Lung,Heart,Tangential Breast Technique,Dose-volume Histograms
- چکیده:
- چکیده انگلیسی: Background: Breast cancer is becoming more frequently diagnosed at early stages with improved long term outcomes. Radiation-related heart disease and lung cancer can occur following radiotherapy for breast cancer. The aim of this study was to evaluate some dosimetric parameters of heart and lung during whole breast radiotherapy. Methods:Twenty five consecutive patients with breast cancer who underwent radiotherapy were included in this study. Plans that employed the 3D conventional radiotherapy technique (Tangential Technique) were generated for each patient. Dose-volume histograms (DVHs) were calculated and dosimetric parameters such as, mean dose/volume receiving a dose 30 Gy (V30), mean dose/ volume receiving a dose 20 Gy (V20) for heart and lung were assessed, respectively. Results:The average of mean dose of heart on left and right side irradiation was 9.68±5.10 Gy and 1.23±1.51 Gy, respectively. The average of mean dose of ipsilateral lung on left and right side irradiation was 14.49±4.07 Gy and 11.69±3.37 Gy, respectively. The percentage of heart volume that received at least 30 Gy was 16.32±9.56% for the left-sided treatment. The percentage of lung volume that received at least 20 Gy was 23.47±11.05% and 24.12±7.77% respectively on the left and right-sided breast irradiation. Conclusion: Tangential beam conventional radiotherapy of the chest wall of postmastectomy breast cancer patients provides the potential to significantly keep the DVH parameters of heart and lung as low as the QUANTEC constrains.
- انتشار مقاله: 26-08-1396
- نویسندگان: Ali Jomehzadeh,Mohammad Hasan Larizadeh,Zahra Jomehzadeh
- مشاهده
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: Opium,Iran,Risk Factor,Case-control,head & neck neoplasms
- چکیده:
- چکیده انگلیسی: Background: Head and Neck (H and N) cancers include malignant tumors of the nasal cavity, pharynx, paranasal sinuses, oral cavity, larynx and salivary glands. Opium use might be related to these cancers. The aim of this study was to investigate the relation between Opium and its Derivatives (O and D) use and the incidence of H and N cancers. Methods: In this case-control study conducted in Kerman, 140 patients with H and N cancers and 280 healthy controls (matched for age, gender, and place of residence) were included. Information about their use of O and D, cigarette smoking, alcohol and diet were collected using a structured questionnaire. Conditional logistic regression was used to investigate the relation between variables. Results: The use of opioids was associated with an increased risk of HandN cancers (Adjusted OR: 8.13; CI: 4.08-16.2). A significant dose-response relation between O and D use was observed, with high use Adjusted OR=8.91; 95% CI: 4.03-19.65 and low use Adjusted OR=6.52; 95% CI: 3.18- 13.36. This dose-response association was stronger in patients with laryngeal cancer and opioids use, with high use Adjusted OR = 11.17; 95% CI=4.48-28.09 and low use Adjusted OR = 9.46; 95% CI= 3.97- 22.52. Conclusion: The results show that opium use can be considered as an important risk factor for H and N cancers. Also in Iran, opium seems to play a more important role than cigarette smoking.
- انتشار مقاله: 13-09-1398
- نویسندگان: Hosniyeh Alizadeh,Ahmad Naghibzadeh Tahami,Narges Khanjani,Vahid Yazdi-Feyzabadi,Hadi Eslami,Vahidreza Borhaninejad,Mohammad Hasan Larizadeh,Ahmad Enhesari,Reza Abbasi-Rayeni,Vahid Moazed,Aliasghar Arabi Mianroodi
- مشاهده