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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Iranian Journal of Veterinary Medicine
- نوع مقاله: Journal Article
- کلمات کلیدی: Growth performance,Broilers,Coccidiosis,Diclazuril,Clopidol
- چکیده: زمینه مطالعه: کوکسیدیوز به عنوان یک بیماری انگلی که بیشترین تأثیر اقتصادی را بر تولید طیور دارد، شناخته شده است. صنعت مدرن پرورش طیور به میزان زیادی وابسته به ترکیبات ضد کوکسیدیوز است. هدف: مطالعه حاضر جهت تعیین و مقایسه کارایی دو ضد کوکسیدیوز شیمیایی (کلوپیدول و دیکلازوریل) بر دفع اووسیست و همچنین اثرات احتمالی آنها بر عملکرد پرورشی و کارایی تغذیهای طیور گوشتی در کوکسیدیوز تجربی انجام شده است. روش کار: تعداد 120 قطعه جوجه یک روزه نژاد Ross 308 بطور تصادفی گروهبندی شدند: کنترل مثبت؛ آلوده به کوکسیدیوز بدون درمان، گروه کنترل منفی؛ بدون آلودگی و بدون درمان، گروه CLO؛ آلوده و درمان شده باکلوپیدول، گروه DIC؛ آلوده و درمان شده با دیکلازوریل. برای ایجاد کوکسیدیوز تمامی گروهها بجز کنترل منفی با اووسیست اسپوروله عفونی در انتهای هفته سوم تلقیح شدند. میزان دفع اووسیست با استفاده از لام مک مستر شمارش گردید. وزن بدن، وزنگیری و ضریب تبدیل غذایی هر هفته اندازهگیری و محاسبه گردید. نتایج: شمارش اووسیست نشان داد که دیکلازوریل در کاهش تعداد اووسیست کارآمدتر از کلوپیدول بود. میانگین وزن بدن در گروه کنترل مثبت از سایر گروهها پایینتر بود. ولی در انتهای مطالعه میانگین وزن در گروههای درمان شده با کلوپیدول و دیکلازوریل با گروه کنترل مثبت تفاوت معنیداری را نشان نداد. در مقایسه وزنگیری میان گروههای مختلف بجز در هفته چهارم و پنجم در سایر هفتهها تفاوت معنیداری مشاهده نشد. بر پایه نتایج بدست آمده از FCR اضافه نمودن ترکیبات آنتی کوکسیدیال اثر معنیداری بر بهبود آن نداشت. نتیجهگیرینهایی: گزارش شده است که برخی از ترکیبات ضدکوکسیدیوز منجر به کاهش مصرف خوراک و ضریب تبدیل غذایی میشوند. به نظر میرسد هیچکدام از ضدکوکسیدیوزهای شیمیایی مورد استفاده در مطالعه حاضر در کنترل زیانهای اقتصادی کوکسیدیوز به طور کامل مؤثر نمیباشند و ارائه استراتژیهای جدید مورد نیاز میباشد.
- چکیده انگلیسی: Background: Coccidiosis is recognized as the parasitic disease that has the greatest economic impact on poultry production. Modern poultry production is largely dependent upon anticoccidials. Objectives: The aim of the present study was to determine and compare the efficacy of two chemical anticoccidials (Clopidol and Diclazuril) on oocyst shedding and their probable effects on growth performance and feed efficiency of broilers in experimental coccidiosis. Methods: One hundred and twenty Ross 308 one day old broilers were randomly assigned into 4 groups: CON+, infected with Eimeria mixed oocysts but not medicated; CON-, not infected and not medicated; CLO, infected and medicated with Clopidol; DIC, infected and medicated with Diclazuril. Chickens in all groups except negative control were inoculated by mixed sporulated oocysts of pathogenic Eimeria at the end of the 3rd week of age. Oocyst shedding was counted using a Mc Master counting chamber. Body weights, body weight gains, and feed conversion ratio were determined on weekly basis. Results: Obtained results showed that Diclazuril was more effective in reducing oocyst shedding than Clopidol. As expected, mean body weight in the positive control group was lower than other groups. But surprisingly, no significant difference was found between Diclazuril or Clopidol treated birds and positive control group, at the end of the experiment. In comparison of weight gain in different treatment groups except for the 4 and 5th week, no significant difference was found in different groups. In the last week of the experiment, difference in weight gain between groups was not significant. According to feed conversion ratio (FCR) results, anticoccidial supplementation did not have any significant effect on improving FCR. ConclusionS: It is reported that some anticoccidials reduce feed consumption and feed conversion. It seems that neither of the present synthetic anticoccidials is completely satisfactory in controlling coccidiosis economic losses and new strategies are urgently required.
- انتشار مقاله: 20-12-1393
- نویسندگان: Hamed Asadi Iraee,Mohammad Asadi Iraee,Mohammad Reza Youssefi,Mohaddeseh Abouhosseini Tabari
- مشاهده
- جایگاه : پژوهشی
- مجله: Avicenna Journal of Phytomedicine
- نوع مقاله: Journal Article
- کلمات کلیدی: Pelargonium roseum,pigeon,Metronidazole,Avian trichomoniasis,Trichomonas gallinae
- چکیده:
- چکیده انگلیسی: Objective: Pelargonium roseum Willd.(Geraniaceae) is widely grown as an ornamental plant due to its strong pleasant rose-like odor. The present study evaluates the antitrichomonal effect of P. roseum essential oil (EO) against Trichomonas gallinae both in vitro and in vivo and compares it to that of metronidazole (MTZ) as a standard antitrichomonal drug.
Materials and Methods: In vitro assays were accomplished in multi-well plates containing MTZ and EO at final concentrations of 2.5, 5, 10, 20, 50, and 100 μg/mL. In vivo assay was carried out on 40 experimentally infected pigeons receiving MTZ and EO at doses of 25 and 50 mg/kg.
Results: The 24-hr MIC of MTZ was 10 µg/mL, while for EO it was 20 µg/mL. Treatment with MTZ 50 mg/kg after 4 days led to full recovery of infected pigeons however EO 50 mg/kg resulted in the same outcome after 5 days. No mortality or clinical side effects were seen in treated birds.
Conclusion: The present study introduced P. roseum EO as a potent natural antitrichomonal agent effective against T. gallinae. Bioactive components of P. roseum can be used as potential therapeutic compounds in development of novel antitrichomonal drugs.- انتشار مقاله: 25-09-1395
- نویسندگان: Mohaddeseh Abouhosseini Tabari,Mohammad Reza Youssefi
- مشاهده
- جایگاه : پژوهشی
- مجله: Advanced Herbal Medicine
- نوع مقاله: Journal Article
- کلمات کلیدی: Zataria multiflora,Growth performance,Serum Biochemical Parameters,Immunity,Broilers
- چکیده:
- چکیده انگلیسی: Background and aims: Zataria multiflora Boiss (ZM) is a thyme-like plant reported to have immunomodulatory properties. This study was aimed to examine effects of ZM essential oil on performance, biochemical and immunological parameters in broilers.
Methods: Two hundred and forty, broiler chickens were divided into 4 groups. CON considered as control group received basal diet, T100, T200 and T400 treated by basal diet supplemented with ZM 100, 200 and 400 mg/kg feed, respectively. Body weight and feed intake were recorded at 14, 28, and 42 days of age. At the end of experiment, eight broilers per group were slaughtered and carcass portion yield was calculated. Humoral immune response efficacy by injection of 5% sheep red blood cell into the pectoral muscle of birds was evaluated.
Results: This study showed that supplementation of ZM promoted the weight gain in T200 as compared to other groups (P<0.05). Also, the best food conversion ratio was achieved in the same group. On the other hand, ZM supplementation in all of the doses used, did not cause significant increase in carcass portion yield (P<0.05), except for liver weight, which was significantly increased in T400. Serum biochemical analysis showed that levels of total protein, albumin and globulin were highest in T200 while the lowest were in T400; addition of ZM especially at the dose of 200 mg/kg improved immune responses in broilers (P<0.05).
Conclusion: According to the results of present study, supplementing broilers diet with ZM could have favorable impact on performance and immunity.- انتشار مقاله: 17-10-1395
- نویسندگان: Khosrow Ghazvinian,Atefeh Araghi,Mohaddeseh Abouhosseini Tabari
- مشاهده
- جایگاه : پژوهشی
- مجله: Advanced Herbal Medicine
- نوع مقاله: Journal Article
- کلمات کلیدی: Leishmania infantum,Pelargonium roseum,Promastigote,Glucantime
- چکیده:
- چکیده انگلیسی: Background and aims: Visceral leishmaniasis so called Kala-azar is one of the important health care problems in the world. Some herbal drugs are noticed because of toxicity and drug resistance against pentavalent antimonials as used in treatment of Kala-azar. In this study, anti-leishmanial activity of Pelargonium roseum Essential oil on the in vitro growth of Leishmania infantum promastigotes in comparison to Glucantime was studied.
Methods: Different concentrations of Pelargonium roseum essential oil on culture of Leishmania infantum promastigote were surveyed with Anti-leishmania activity assays at 24 hr and 48 hr at 570 nm wavelength. All the data were analyzed by using SPSS version and anti-leishmanial potency of the oil extract of Geranium in different concentration were compared with standard dose of Glucantime.
Results: All concentration in 24 hr showed no remarkable difference. 25, 50 and 100 µL/ml efficacy was same as Glucantime on the growth of promastigotes in 24 hr MTT. All concentrations except 1µL/ml in 48hr MTT had resemble impact on the growth of promastigotes. 5 µL/ml concentration of Pelargonium roseum essential oil was significant difference effect on the parasite (P= 0.043) in 48hr.
Conclusion: Pelargonium roseum essential oil doesn’t treat Leishmania infantum promastigote quickly. After 48 hr, 5 µL/ml concentration can be a suitable candidate in clinical trials.- انتشار مقاله: 04-07-1395
- نویسندگان: Mohaddeseh Abouhosseini Tabari,Elham Moghaddas,Bibi Razieh Hosseini Farash,Mohammad Amin Ebrahimi,Nilofar Nabavi Mousavi,Mohammad Reza Youssefi
- مشاهده