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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Trends in Pharmaceutical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: Staphylococcus aureus,enterotoxin genes,pathogenicity,Multiplex-PCR
- چکیده:
- چکیده انگلیسی: Staphylococcus aureus (S. aureus) is a pathogen in community-acquired or hospital infections. Hence, the identification of this pathogen in clinical samples is a health concern and demands continued surveillance and close monitoring. In the current study, S. aureus strains were isolated from various clinical specimens in the Shariati Hospital, Tehran, Iran. Samples were studied to discover S. aureus enterotoxin-coding genes A (sea), B (seb), C (sec), and D (sed). It was found that 21% enterotoxigenic S. aureus harbored sea gene, 39% were carried seb gene, 37% were positive for sec-gene, and 3% were carried sed gene. None of all S. aureus strains harbored more than one of the enterotoxigenic genes. Based on the data obtained from the current study, it could be suggested that seb and sec genes are good candidates for the identification of S. aureus in clinical specimens. Further investigations are required to discover the association between these genes and the pathogenicity of this bacteria, and finally using these data in clinical settings.
- انتشار مقاله: 15-08-1398
- نویسندگان: Vahid Ghanbarinejad,Aboozar Kazemi,Mina Zareei,Reza Heidari,Hossein Hassanian-Moghaddam
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Dentistry, Shiraz University of Medical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: Flare-up,Nano sealer,AH-26 Sealer
- چکیده:
- چکیده انگلیسی: Statement of the Problem: Some patients may report moderate-to-severe pain and/or swelling following root canal treatment that is undesirable for both the patient and dentist and may requires an unscheduled emergency visit by patients to relieve the symptoms.
Purpose: The aim of this study was to evaluate the post-treatment flare-up incidence following application of nano zinc oxide-eugenol (NZOE) sealer in mandibular first molars with irreversible pulpitis.
Materials and Method: This single-blinded study was performed on 60 patients having mandibular first molars with irreversible pulpitis. After signing the written consent form, the patients were randomly divided into two groups considering their age range (20-34 and 35-50 years). Individuals without systemic diseases and with a first mandibular molar diagnosed with irreversible pulpitis due to caries, no sinus track and abscess, normal periapical radiographic appearance, no spontaneous pre-treatment pain, not having taken any medication for at least 8 h before the treatment visit were included in this study. Patients of both sexes ranging from 20 to 50 years of age were selected.
In order to obturate the root canal space, AH26 sealer was used in the one group and synthesized NZOE was applied in another group. The patients were then given questionnaires to report the severity of pain and presence of swelling during 6, 18, 24 and 48 hours of follow-up. The data was analyzed using SPSS v.19 software applying repeated measures ANOVA. The significance level was set at 0.05.
Results: The severity of pain was significantly lower in NZOE group at 24 hours post-treatment (p = 0.003) Patients reported no symptoms of swelling in any group.
Conclusion: NZOE sealer manifested satisfactory results and could be regarded as a promising substitute to routine sealers due to the fact that patients may experience less pain during the first hours after receiving root canal therapy.- انتشار مقاله: 01-08-1398
- نویسندگان: Maryam Javidi,Mina Zareei,Ehsan Ashrafpour,Maryam Gharechahi,Hossein Bagheri
- مشاهده