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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Evidence Based Care Journal
- نوع مقاله: Journal Article
- کلمات کلیدی: Echocardiography,Pulmonary hypertension,Thalassemia Major
- چکیده:
- چکیده انگلیسی: Pulmonary arterial hypertension (PAH) is a progressive disease with high morbidity and mortality rates. Research has shown that PAH has a prevalence rate of 10-79% in thalassemia major patients. This cross-sectional study was carried out in 2014 to determine the prevalence and risk factors of PAH in all thalassemia major patients of over 18 years of age in Ilam, Iran. A cardiologist measured systolic pulmonary artery pressure (SPAP) by using Doppler echocardiography. SPAP of higher than 25 mm Hg was defined as PAH criterion. The obtained data was analyzed using SPSS, version 17. Of the 36 studied patients, 17 (47.2%) were male and 19 (52.8%) were female. The mean age of the patients was 26.0±5.6 years. The prevalence of PAH in the thalassemia major patients was estimated to be 47.2% and the mean SPAP was determined to be 26.2±14.6 mm Hg. Among the examined PAH risk factors, only the history of pulmonary disease (0.02) and transfusion (0.03) was found to be significant.
- انتشار مقاله: 11-08-1395
- نویسندگان: Milad Azami,Askar Sufi Nia,Mohammad Hossein YektaKooshali,Sasan Nikpay,Yaeghoob Madmoli,Mohammad Malekshahi,Esmaiil Ghasemi Pashaklaee
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Neonatology
- نوع مقاله: Journal Article
- کلمات کلیدی: Iran,mortality,Meta-Analysis,Intensive Care Unit,Neonatal
- چکیده:
- چکیده انگلیسی: Background: Neonatal mortality rate is an important health index. The present study was conducted to determine the mortality rate and its causes in neonatal intensive care units (NICUS) in Iran.
Methods: Online search was done without time limit until June 2018 in several databases, such as PubMed, Web of Science (ISI), Scopus, Magiran, Barakat Knowledge Network System, SID, Iranian National Library, Regional Information Center for Science and Technology (RICST), Google Scholar search engine, and Iranian journals. The articles were qualitatively assessed after evaluating the inclusion and exclusion criteria. The Cochran's Q test and I2 index were used to determine the heterogeneity between studies. Meta-analysis was done based on a random effects model using Comprehensive Meta-Analysis Software (version 2).
Results: Thirty-one eligible studies were analyzed. The mortality rate in 24,995 neonates admitted to NICUs in Iran was estimated to be 11.40% (95% CI: 9.10-14.20). The lowest mortality rate reported as 7.70% (95% CI: 6.01-9.82) was related to the Center of Iran, and the highest mortality rate was reported as 19.26% (95% CI: 15.82-23.24) in the west of Iran. In this regard, the difference was statistically significant (P<0.001). The most common causes of mortality in NICUs in Iran were prematurity (44.14% [95% CI: 31.95-57.08]), respiratory distress syndrome (RDS) (31.93% [95% CI: 22.83-42.66]), congenital malformation (16.09% [95% CI: 12.85-19.95]), septicemia (12.66% [95% CI: 8.87-17.75]), and asphyxia (7.58% [95% CI: 4.63-12.19]).
Conclusion: The most common causes of mortality in Iranian neonates were prematurity, RDS, and congenital anomalies. We also found the mortality rate to be acceptable (11.4%). To reduce the mortality rate, we recommend performing prenatal screening tests and genetic counseling. In addition, maternal care during pregnancy should be improved to reduce premature delivery.- انتشار مقاله: 11-09-1397
- نویسندگان: Parviz Karimi,Leily Mahmudi,Milad Azami,Gholamreza Badfar
- مشاهده
- جایگاه : پژوهشی
- مجله: Evidence Based Care Journal
- نوع مقاله: Journal Article
- کلمات کلیدی: Echocardiography,Pulmonary hypertension,Thalassemia Major
- چکیده:
- چکیده انگلیسی: Pulmonary arterial hypertension (PAH) is a progressive disease with high morbidity and mortality rates. Research has shown that PAH has a prevalence rate of 10-79% in thalassemia major patients. This cross-sectional study was carried out in 2014 to determine the prevalence and risk factors of PAH in all thalassemia major patients of over 18 years of age in Ilam, Iran. A cardiologist measured systolic pulmonary artery pressure (SPAP) by using Doppler echocardiography. SPAP of higher than 25 mm Hg was defined as PAH criterion. The obtained data was analyzed using SPSS, version 17. Of the 36 studied patients, 17 (47.2%) were male and 19 (52.8%) were female. The mean age of the patients was 26.0±5.6 years. The prevalence of PAH in the thalassemia major patients was estimated to be 47.2% and the mean SPAP was determined to be 26.2±14.6 mm Hg. Among the examined PAH risk factors, only the history of pulmonary disease (0.02) and transfusion (0.03) was found to be significant.
- انتشار مقاله: 11-08-1395
- نویسندگان: Milad Azami,Askar Sufi Nia,Mohammad Hossein YektaKooshali,Sasan Nikpay,Yaeghoob Madmoli,Mohammad Malekshahi,Esmaiil Ghasemi Pashaklaee
- مشاهده
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: Prostate cancer,Meta-Analysis,selenium
- چکیده:
- چکیده انگلیسی: Background: Evidence of relationship between selenium and prostate cancer has been inconsistent. The present metaanalysis was conducted to determine relationship between selenium and prostate cancer. Methods: A systematic review and meta-analysis was carried out using preferred reporting items for systematic reviews and meta-analysis (PRISMA). We searched PubMed, Scopus, Web of Science, ScienceDirect, Embase, CINAHL, Cochrane Library, EBSCO and
Google scholar search engines and the reference lists of the retrieved papers for relevant data, without any limitation
regarding language or time until 2016. Heterogeneity among studies was evaluated using Q test and I2 Index. Finally,
a random effects model was used for combining results using STATA software version 11.1. Psignificant. Results: Thirty-eight studies including 36,419 cases and 105,293 controls were included in the final analysis. The pooled relative risk (RR) of relation between selenium and prostate cancer was 0.86 (95% Confidence Interval [CI]:0.78-0.94). Sub-group analyses based on case-control, cohort, and RCT studies gave values of 0.89 (95% CI:0.80-1.00), 0.77 (95% CI: 0.52-1.14) and 0.90 (95% CI: 0.74-1.09), respectively. RRs based on serum, plasma and nail samples were 0.69 (95% CI: 0.51-0.95), 0.85 (95% CI: 0.61-1.17), 0.66 (95% CI: 0.41-1.05), respectively. According to 10 studies, investigated the relation between advanced prostate cancer and selenium in which the RR was 0.67 (95% CI: 0.52-0.87). Conclusions: This meta-analysis indicated that selenium most probably has a protective role against development of prostate cancer and its progression to advanced stages. Therefore, selenium supplementation can be proposed for prevention of prostate cancer.- انتشار مقاله: 10-11-1395
- نویسندگان: Koroush Sayehmiri,Milad Azami,Younes Mohammadi,Ali Soleymani,Zeinab Tardeh
- مشاهده
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: Prostate cancer,Calcium,systematic review and meta-Analysis
- چکیده:
- چکیده انگلیسی: Background: Controversial results have been reported concerning the influence of calcium intake on prostate cancer
risk. The aim of this study was to determine any association between total calcium (in the diet and in supplements) intake
and prostate cancer. Materials and Methods: The present systematic review and meta-analysis study was carried out
following a PRISMA guidelines. Two reviewers independently using MeSH keywords searched international databases
including PubMed, Science Direct, Cochrane, EMBASE, Web of Science, CINAHL, EBSCO and search engines such
as Google Scholar. The searches were performed without any time limit until May 2016. The results were pooled
using a random effects model and homogeneity was confirmed using the Q test and I2 index. Subgroup analyses was
performed according to continents and study designs. The data were analyzed using STATA software version 3.2, with
pfinal meta-analysis. The main age range of the participants was 50 to 70 years. The relative risks (RR) for total calcium
with total prostate cancer, localized prostate cancer, and advance prostate cancer were estimated to be 1.15 (95% CI:
1.04-3.46), 1.05 (95% CI: 0.96-1.14), and 1.15 (95% CI: 0.89-1.50), respectively. Only the relationship between total
calcium and total prostate cancer was significant (P<0.05). Conclusions: High calcium intake can be considered as a
risk factor for total prostate cancer. Therefore, calcium intake might be a target for prevention.- انتشار مقاله: 04-07-1396
- نویسندگان: Shoboo Rahmati,Milad Azami,Ali Delpisheh,Mohammad Reza Hafezi Ahmadi,Koroush Sayehmiri
- مشاهده