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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: Iran,Poisoning,Women,Pregnancy,Suicide
- چکیده:
- چکیده انگلیسی: Background
Suicidal attempt is an important phenomenon among pregnant women in Iran. This study was designed to determine the epidemiological status and risk factors of suicidal attempts by poisoning in pregnant women.
Materials and Methods
All pregnant women who were referred to the poisoning department of Imam Reza Hospital (Mashhad, Iran) from November 2016 to November 2017, were evaluated in terms of suicidal attempts. Cases of poisoning with a suicidal intent were included in the study after obtaining informed consent. A checklist, including the baseline characteristics, risk factors, and underlying causes of suicide, was completed for every participant anonymously.After regaining consciousness, the participants were interviewed by a psychiatrist in the consultation room for 20 minutes, and the underlying psychiatric disorders, mood disorders, stressors, and suicidal thoughts were evaluated.Finally, the collected data were analyzed using SPSS software (version 16.0).
Results
Among 40 pregnant women evaluated in this study, 87.5% did not have a stable job or income,55% had difficult living conditions, 45% suffered from sleep disorders, 45% had suicidal thoughts, and 42.5% reported addiction in husband. In addition, 32.5% of women had a history of depression, 32.5% had previous suicidal attempts, 32.5% had abortion thoughts, 20% had a family history of suicide attempt,17.5% were addicts, and 17.5% had a history of self-injury.
Conclusion
This study indicated that the most important factors associated with suicidal attempts by poisoning in pregnant women include lack of job and income, difficult living conditions, and history of psychiatric problems and addiction.- انتشار مقاله: 07-12-1397
- نویسندگان: Anahita Alizadeh,Fatemeh Said Afkhamoshoara,Mohammad Hussein Kamaloddini,Forough Rakhshanizadeh,Mehdi Talebi
- مشاهده
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: Acute Lymphoblastic Leukemia,Protein expression,Resveratrol,Prednisolone,MDR1 gene
- چکیده:
- چکیده انگلیسی: Objective: Chemotherapy is the most widely recognized technique to regard leukemia and also different sorts of
human tumors. In any case, tranquilize protection has stayed as the primary test against the adequacy of medications.
Besides, having different unfriendly impacts, chemotherapy drugs are getting to be traded by characteristic modalities for
growth treatment. In such manner, natural segments, for example, resveratrol and prednisolone have been recognized to
sharpen the leukemic cells to modified cell demise through an arrangement of complex procedures. In this investigation,
we have analyzed effect of 15, 50 and 100μM of resveratrol and 700μM of prednisolone on the human multidrug
protection quality 1 (MDR1) as a notable marker for cell sedate protection. We assessed the impact of resveratrol and
prednisolone on MDR1 protein expression in the CCRF-CEM cell line as an agent for intense lymphoblastic leukemia.
The investigation was planned to clear up whether. Materials and methods: CCRF-CEM cells linage get under
drug treatment with use of resveratrol and prednisolone. Western blot use at 24 and 48 hours with different doses of
resveratrol and prednisolone to analysis of MDR1 expression changes. Results: Effect of 15, 50, and 100 micro molar
of resveratrol and 700 micro molars of prednisolone on CCRF-CEM cells led to the MDR1 decrease. Western blot use
for evaluation of MDR1 protein expression changes. Conclusion: In the present study, we observed that resveratrol
and prednisolone, with a dose-dependent effect, can reduce the expression of the MDR1 protein. This reduction of
expression demonstrates that resveratrol and prednisolone can overcome to drug resistance created by MDR1.- انتشار مقاله: 14-07-1397
- نویسندگان: Mehdi Talebi,Sina Bahar Aghdam,Ako Azimi,Hamed Mohammadi,Somayyeh Karimi Yonjali,Maryam Asariha,Milad Zadi Heydarabad
- مشاهده