در هنگام جستجو کلمه در قسمت عنوان میتوانید کلمات مورد جستجو را با کاراکتر (-) جدا کنید.
کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: Diagnosis,treatment,Thyroid cancer,lncRNA,genetic alterations
- چکیده:
- چکیده انگلیسی: Thyroid cancer (TC) is the most common cancer of endocrine system. TC can be subdivided into 4 different entities, papillary, follicular, medullary and anaplastic thyroid cancer. Among them, anaplastic thyroid cancer has the poorest prognosis. Exploring new therapeutic approach may entail favorable prediction as well as increasing overall survival rate of patients. Long non-coding RNAs (lncRNAs), have vast implications in different cancer types. Although they are not transcribed into proteins, they can act as a harness in regulating a plethora of biological functions. They have been implicated in a decisive role in gene expression via modulation of both coding and non-coding RNAs. This article discuss the multi-facet role of lncRNA in thyroid cancer biology.
- انتشار مقاله: 28-10-1397
- نویسندگان: Zeeshan Javed,Faiez Ahmed Shah,Sadegh Rajabi,Qamar Raza,Zaheer Iqbal,Mukhtar Ullah,Touqeer Ahmad,Bahare Salehi,Mehdi Sharifi-Rad,Raffaele Pezzani,Farooq Yaqoob,Haleema Sadia,Marcello Iriti,Javad Sharifi-Rad,William C Cho
- مشاهده