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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Gas Processing Journal
- نوع مقاله: Journal Article
- کلمات کلیدی: Gas cyclone,tangential velocity,axialvelocity,numerical study,cyclone geometry
- چکیده:
- چکیده انگلیسی: Air and gas pollution has become a critical problem endangering species life worldwide. Among all technologies proposed to solve this problem, separators including cyclones have attracted tremendous attention towards separation of airborne and solid particles from air and gases due to their simplicity of construction, low operating costs and flexibility in tolerating hard conditions. In this study, a numerical investigation of solid particle separation in gas-particle cyclones is presented. The Reynolds stress turbulence model (RSM) is employed to simulate a strongly swirling turbulent air flow along with the discrete phase model (DPM) to trace the particles. A wide range of geometrical parameters is studied to find out how they affect the flow field pattern and particle separation in cyclones, hence the cyclone performance. It is shown that the pressure drop and the tangential velocity decrease with inlet angle increment. In addition, the static pressure increases due to a small diameter reduction originating from the reduction in cone angle. The static pressure is significantly reduced in the cyclone with higher cone height when the axial velocity changes are not noticeable. This parametric study developed based on a numerical model, can have a great potential for design and fabrication of cyclones used in gas-solid separation industries.
- انتشار مقاله: 10-05-1397
- نویسندگان: Mehdi Miansari ,Ghasem Najarian Darounkolaie,Behnam Amini
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Kerman University of Medical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: Diphenhydramine,Quince seed mucilage,Aluminum magnesium,Topical anesthesia
- چکیده:
- چکیده انگلیسی: Background & Aims: The topical anesthetic effects of diphenhydramine combined with ingredients such as aluminum and magnesium hydroxide have been used for many years in modern medicine. Due to the limited durability of anesthetic mouthwashes due to saliva secretion and the spreading use of herbal and natural medicines in pharmacotherapy, this study was designed to formulate diphenhydramine in the mucilage of quince seed and evaluate its in-vitro properties and clinical anesthetic effect. Methods: This research was a descriptive laboratory and double-blind clinical study on 4 formulations. Diphenhydramine in quince seed mucilage, diphenhydramine and aluminum magnesium hydroxide combination, diphenhydramine solution, and diphenhydramine elixir and aluminum magnesium hydroxide combination were administered to 12 healthy male volunteers. The age range of the participants was 20 to 30 years. All subjects signed informed consent forms. Diphenhydramine release from the formulations was assessed through cellulosic membrane in Franz diffusion cell. The clinical evaluation of the formulations on healthy volunteers was conducted through prescribing mouthwash use for 2 minutes and controlling the duration its effect in 10, 20, and 30 minutes after administration using a questionnaire. Data analysis was performed using Kruskal-Wallis and Mann-Whitney tests. Results: The duration of effect of diphenhydramine in quince seed mucilage base was at least 3 times longer than diphenhydramine solution and aluminum Mg and the diphenhydramine elixir and aluminum Mg combination. Clinical evaluation showed that the diffusion coefficient of diphenhydramine in the quince seed mucilage base was significantly different from that of the diphenhydramine solution and diphenhydramine and aluminum Mg combination (P < 0.010). However, it was not significantly different from the diphenhydramine elixir and aluminum Mg combination (P = 0.204). Conclusion: The results of in-vitro and clinical studies showed that diphenhydramine in mucilage of quince seed can sustain and control the release of diphenhydramine and can be administered instead of the diphenhydramine elixir and aluminum Mg combination.
- انتشار مقاله: 22-04-1395
- نویسندگان: Zahra Ataee,Ghorban Abedini,Razieh Sadat Rezvaninejad,Mehdi Ansari
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Dentistry, Shiraz University of Medical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی:
- چکیده:
- چکیده انگلیسی: Statement of the Problem: Use of traditional medicine to relieve human sufferings has a very long history. The effects of these plants in wound curing and subsequently making the best mucosa patch for treatment of oral ulcers is still under investigation.Purpose: The main goal of present research work is to assess the efficacy of Myrtus communis L., Camellia sinensis L. and Zataria multiflora Boiss. on oral ulcer recovery process in rats.Materials and Method: In this study, 60 healthy adult male rats in 5 groups were investigated. A wound with 2 mm diameter was punched into the hard palate of each rat. For topical application, a mucosa patch of materials or blank was packed into the wound. Histological samples were harvested on post injury days 2, 4, 6, and 8.Results: This study showed that there were no significant differences between groups in the reduction of weight. Comparison of clinical wound size showed that group Myrtus communis L had the greatest reduction in wound size on days 4, 6 and 8, which was significantly different from the other groups. The highest thickness of epithelium was observed in groups Myrtus communis L and Camellia sinensis L on days 6 and 8. Group Myrtus communis L showed the highest values on days 6 and 8. This study showed a lower mononuclear cell counts in group Myrtus communis L on days 6 and 8 compared to other groups which was statistically significant.Conclusion: The results of the present study showed that Myrtus communis L. has significant effects on oral wound healing processes. These favorable results might introduce a new group of material or medicine derived from this plant.
- انتشار مقاله: 14-09-1394
- نویسندگان: Maryam Alsadat Hashemipour,Sodabeh Lotfi,Molok Torabi,Fariba Sharifi,Mehdi Ansari,Amirreza Ghassemi,Saied Sheikhshoaie
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Biotechnology
- نوع مقاله: Journal Article
- کلمات کلیدی: Antibacterial activities,Fe3O4,Magnetic nanoparticles,Gentamicin
- چکیده:
- چکیده انگلیسی: Background: Magnetic nanoparticles (MNPs) loaded by various active compounds can be used for targeted drug delivery.
Objectives: In the present study, the Fe3O4 magnetic nanoparticles that contained gentamicin were prepared and their antibacterial activities were studied.
Materials and Methods: MNPs containing gentamicin (G@SA-MNPs) were prepared using sodium alginate (SA) as a surface modifier. After and before coating, the prepared MNPs were characterized using transmission electron microscopy (TEM), X-ray diffraction spectroscopy (XRD), Fourier transform infrared spectroscopy (FTIR), and vibrating sample magnetometer (VSM). Finally, the antibacterial effect of the MNPs was investigated by a conventional serial agar dilution method.
Results: Particle size distribution analysis showed that the size of MNPs, before and after coating, was in the range of 1-18 nm and 12-40 nm, respectively. The magnetization curve of G@SA-MNPs (with saturation magnetization of 27.9 emu.g-1) confirmed ferromagnetic property. Loading gentamicin on the surface of MNPs was qualitatively verified by FTIR spectrum. Quantitative analysis measurements indicated the gentamicin loading on SA-MNPs as 56.7 ± 5.4%. The measured MICs of G@SA-MNPs for Pseudomonas aeruginosa (PTTC 1574) was 1.28 μg.mL-1. The sub-MIC (0.64 μg.mL-1) concentration of G@SA-MNPs in nutrient broth could successfully inhibit the growth of P. aeruginosa for 14 hours.
Conclusions: Loading gentamicin on the SA-MNPs exhibited reasonable antibacterial effects against P. aeruginosa.
- انتشار مقاله: 06-02-1395
- نویسندگان: Banafsheh Douzandeh-Mobarrez,Mehdi Ansari-Dogaheh,Touba Eslaminejad,Maryam Kazemipour,Mojtaba Shakibaie
- مشاهده
- جایگاه : پژوهشی
- مجله: Gas Processing Journal
- نوع مقاله: Journal Article
- کلمات کلیدی: Gas cyclone,tangential velocity,axialvelocity,numerical study,cyclone geometry
- چکیده:
- چکیده انگلیسی: Air and gas pollution has become a critical problem endangering species life worldwide. Among all technologies proposed to solve this problem, separators including cyclones have attracted tremendous attention towards separation of airborne and solid particles from air and gases due to their simplicity of construction, low operating costs and flexibility in tolerating hard conditions. In this study, a numerical investigation of solid particle separation in gas-particle cyclones is presented. The Reynolds stress turbulence model (RSM) is employed to simulate a strongly swirling turbulent air flow along with the discrete phase model (DPM) to trace the particles. A wide range of geometrical parameters is studied to find out how they affect the flow field pattern and particle separation in cyclones, hence the cyclone performance. It is shown that the pressure drop and the tangential velocity decrease with inlet angle increment. In addition, the static pressure increases due to a small diameter reduction originating from the reduction in cone angle. The static pressure is significantly reduced in the cyclone with higher cone height when the axial velocity changes are not noticeable. This parametric study developed based on a numerical model, can have a great potential for design and fabrication of cyclones used in gas-solid separation industries.
- انتشار مقاله: 10-05-1397
- نویسندگان: Mehdi Miansari ,Ghasem Najarian Darounkolaie,Behnam Amini
- مشاهده
- جایگاه : پژوهشی
- مجله: Addiction and Health
- نوع مقاله: Journal Article
- کلمات کلیدی:
- چکیده:
- چکیده انگلیسی: Abstract Backgrond: Drug abuse, especially opium abuse, is a major public health problem in Iran. Recent reports suggest that opium sellers cheat their customers by adding lead to the opium. Contaminated opium can threaten the health of consumers. The present study aimed to compare the serum level of lead between opium dependents and a control group. Methods: This was a cross-sectional study in which 50 opium dependents aged 20 to 60 years old were compared with a control group of 43 non-dependents who were matched with the case group in terms of sex and age. The serum level of lead and liver function tests including serum total bilirubin, AST, ALT, Alkaline-phosphatase and hemoglobin were measured for all subjects. Findings: The mean level of serum lead concentration in opium dependents and controls was 3929.358 ± 147.67 and 3532.721 ± 1141.53, respectively and the difference was not statistically significant. There was no significant correlation between serum level of lead and age, duration of opium dependency, serum total bilirubin, hemoglobin, AST, ALT, and Alkaline-phosphate. Conclusion: Although there was no significant relationship between opium consumption and serum level of lead, the concentration of lead in dependents' serum was higher than controls. Further studies are needed to approve this relationship to be used for screening and on time diagnosis of opium dependents. Keywords: Opium, Addiction, Lead poisoning, Serum level.
- انتشار مقاله: 18-08-1389
- نویسندگان: Mohammad Mehdi Hayatbakhsh Abbasi,Mehdi Ansari,Armita Shahesmaeili,Ali Qaraie
- مشاهده
- جایگاه : پژوهشی
- مجله: Addiction and Health
- نوع مقاله: Journal Article
- کلمات کلیدی:
- چکیده:
- چکیده انگلیسی: Abstract Backgrond: Drug abuse, especially opium abuse, is a major public health problem in Iran. Recent reports suggest that opium sellers cheat their customers by adding lead to the opium. Contaminated opium can threaten the health of consumers. The present study aimed to compare the serum level of lead between opium dependents and a control group. Methods: This was a cross-sectional study in which 50 opium dependents aged 20 to 60 years old were compared with a control group of 43 non-dependents who were matched with the case group in terms of sex and age. The serum level of lead and liver function tests including serum total bilirubin, AST, ALT, Alkaline-phosphatase and hemoglobin were measured for all subjects. Findings: The mean level of serum lead concentration in opium dependents and controls was 3929.358 ± 147.67 and 3532.721 ± 1141.53, respectively and the difference was not statistically significant. There was no significant correlation between serum level of lead and age, duration of opium dependency, serum total bilirubin, hemoglobin, AST, ALT, and Alkaline-phosphate. Conclusion: Although there was no significant relationship between opium consumption and serum level of lead, the concentration of lead in dependents' serum was higher than controls. Further studies are needed to approve this relationship to be used for screening and on time diagnosis of opium dependents. Keywords: Opium, Addiction, Lead poisoning, Serum level.
- انتشار مقاله: 18-08-1389
- نویسندگان: Mohammad Mehdi Hayatbakhsh Abbasi,Mehdi Ansari,Armita Shahesmaeili,Ali Qaraie
- مشاهده