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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Trends in Pharmaceutical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی:
- چکیده:
- چکیده انگلیسی: The liver is continuously exposed to a variety of xenobiotics. Several xenobiotics are identified which act as hepatotoxicants. Hence, finding protective agents for ameliorating xenobiotics-included liver injury has a great value. Eisenia foetida, a kind of “earthworm,” is a source of a wide range of bioactive components. Several investigations have been evaluated the E. foetida extract (EFX) for biomedical and nutritional applications. The current study was designed to evaluate the potential hepatoprotective properties of EFX in two experimental models of hepatic damage. Acetaminophen (APAP; 1 g/kg, i.p) was administered as the animal model of acute liver injury in mice. Bile duct ligated (BDL) rats were used as the animal model of chronic hepatic damage. Severe elevation in tissue biomarkers of oxidative stress including lipid peroxidation and hepatic glutathione depletion was evident in both APAP-treated and BDL animals. Moreover, serum biomarkers of liver injury were drastically increased in both acute and chronic animal models of hepatotoxicity. Significant liver tissue histopathological alterations including tissue necrosis, vascular congestion, and inflammatory cells infiltration were detected in APAP-treated and BDL animals. On the other hand, it was found that EFX supplementation (100, 200, 500, and 700 mg/kg, i.p) mitigated oxidative stress markers, decreased serum biomarkers of liver injury, and alleviated liver tissue histopathological changes. The hepatoprotection provided by EFX supplementation in the current study might be mediated through its potential antioxidative mechanisms.
- انتشار مقاله: 10-06-1397
- نویسندگان: Akram Jamshidzadeh,Fatemeh Dabagh,Omid Farshad,Mohammad Mehdi Ommat,Azadeh Mahdavinia,Negar Azarpira,Maryam Shahbazi,Asma Najibi,Reza Heidari
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Energy Management and Technology
- نوع مقاله: Journal Article
- کلمات کلیدی: Energy,Security,Information and Communication Technology,Standards,Smart city
- چکیده:
- چکیده انگلیسی: Nowadays, the negative effects of greenhouse gas emission, air pollution, and global warming have been increased exponentially due to population growth, especially in urban areas. To handle urbanization with minimal environmental pollution, the smart city concept has been introduced and extended significantly. Worldwide concerns on social welfare and lifestyle quality are the other important reasons that motivate cities to become smarter and more intelligent. The smart cities try to promote economic growth and improve the quality of life by providing regional development and technology utilization, especially smart-based technologies by using information and communication technology, and services. In this paper, it is attempted to present the definition, concepts, and standards to make the necessary arrangements and involved challenges in smart cities focusing on the power system requirements. Finally, by reviewing some proposed frameworks regarding the smartization road map, a sample road-map is described, especially in pioneer smart cities around the world.
- انتشار مقاله: 03-08-1398
- نویسندگان: Hamdi Abdi,Maryam Shahbazitabar
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Energy Management and Technology
- نوع مقاله: Journal Article
- کلمات کلیدی: Dynamic programming,Hierarchical combination,Power generation scheduling,Priority list,Unit commitment problem
- چکیده:
- چکیده انگلیسی: Unit commitment problem (UCP) is an essential concept in electricity generation due to various economical and environmental concerns. This paper presents a hierarchical combination algorithm for solving the UCP which is able to minimize the simulation time as well as the operational cost. Furthermore, the binary decision variables, determining the state of unit (on/off), are produced in each hour considering the demand and spinning reserve requirements (SRRs). Minimum up and down time constraints are applied in order to reduce the solution space. Finally, the economic dispatch (ED) is carried out for the feasible commitments obtained in each interval respect to the power generation limitations. In addition, the Priority List (PL) and Exhaustive Enumeration (EE) methods are implemented during the load increases and decreases, respectively. The proposed method has been implemented and applied to the standard power systems and the obtained results verify the relevant acceptable computational time with the optimal cost compared to the other well-known methods in the literature.
- انتشار مقاله: 29-04-1396
- نویسندگان: Maryam Shahbazitabar,Hamdi Abdi
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Pharmaceutical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: Protease,Bacillus sp,Moderately halophilic
- چکیده:
- چکیده انگلیسی: Screening and identification of moderately halophilic protease producing bacteria from different regions of Maharloo, a hypersaline lake in the southern area of Iran, were the objectives of this study. In the preliminary screening, 16 isolates exhibited proteolytic activity on saline skim milk agar. All isolates were able to grow comfortably in the media containing 7-15% of salt. Protease activity was assessed through in vitro colorimetric assays for general proteases and the strains were identified by 16S rDNA molecular marker. In comparison to Gram-negative bacteria, the Gram-positive rods, displayed higher proteolytic activities, and Bacillus sp. BCCS 041 was found as the highest protease producing strain with 0.43 U/ml of supernatant activity.
- انتشار مقاله: 29-11-1389
- نویسندگان: Younes Ghasemi,Sara Rasoul-Amini,Alireza Ebrahiminezhad,Aboozar Kazemi,Maryam Shahbazi,Najme Talebnia
- مشاهده