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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Archives of Bone and Joint Surgery
- نوع مقاله: Journal Article
- کلمات کلیدی: Antioxidant,Spinal anesthesia,Diabetic foot,General anesthesia,Lipid peroxide,Foot amputation
- چکیده:
- چکیده انگلیسی: Background: Anesthesia is performed in two major methods including regional and general.
The aim of this study was to compare the effect of anesthesia method (spinal and general) on oxidative stress in
diabetic patients underwent diabetic amputation surgery.
Methods: In this randomized control trial, 40 patients with diabetic foot who were candidate for foot amputation
surgery at our academic hospital in 2013, were selected and divided into two groups based on anesthesia method.
Lipid peroxide level and serum total antioxidant capacity (TAC) were measured before anesthesia induction and one
hour after surgery. As the normal range, the findings obtained from 23 healthy volunteers were utilized.
Results: Mean age was 54.9±11.21 and 52.4±11.23 years in the spinal anesthesia (SA) and the general anesthesia
(GA) group, respectively (P=0.49). Serum TAC in GA group increased from 1.03±0.04 mM to 2.98±0.7 mM. In SA
group, the increase of serum TAC from 1.22±0.11 mM to 3.42±0.5 mM was observed that indicated the increase of
serum TAC in both groups was not significantly different (P=0.21). Serum Malondialdehyde (MDA) in GA and SA
groups did not show a significant difference before surgery (31.14±3.9 mM vs. 29.06±2.49 mM in GA and SA groups,
respectively) (P=0.31), while it was significantly different after surgery (23.14±2.6 mM and 19.24±2.7 mM in GA and SA
groups, respectively) (P=0.03).
Conclusion: lower limb amputation can help to control oxidative stress in diabetic patients; and considering serum
MDA as a marker of oxidative stress, SA seems to be more effective to control this problem.- انتشار مقاله: 07-10-1395
- نویسندگان: Arash Peivandi Yazdi,Alireza Bameshki,Maryam Salehi,Gholamhosein Kazemzadeh,Majid Sharifian Razavi,Shaghayegh Rahmani,Seyed Isaac Hashemy
- مشاهده
- جایگاه : پژوهشی
- مجله: Archives of Bone and Joint Surgery
- نوع مقاله: Journal Article
- کلمات کلیدی: Antioxidant,Spinal anesthesia,Diabetic foot,General anesthesia,Lipid peroxide,Foot amputation
- چکیده:
- چکیده انگلیسی: Background: Anesthesia is performed in two major methods including regional and general.
The aim of this study was to compare the effect of anesthesia method (spinal and general) on oxidative stress in
diabetic patients underwent diabetic amputation surgery.
Methods: In this randomized control trial, 40 patients with diabetic foot who were candidate for foot amputation
surgery at our academic hospital in 2013, were selected and divided into two groups based on anesthesia method.
Lipid peroxide level and serum total antioxidant capacity (TAC) were measured before anesthesia induction and one
hour after surgery. As the normal range, the findings obtained from 23 healthy volunteers were utilized.
Results: Mean age was 54.9±11.21 and 52.4±11.23 years in the spinal anesthesia (SA) and the general anesthesia
(GA) group, respectively (P=0.49). Serum TAC in GA group increased from 1.03±0.04 mM to 2.98±0.7 mM. In SA
group, the increase of serum TAC from 1.22±0.11 mM to 3.42±0.5 mM was observed that indicated the increase of
serum TAC in both groups was not significantly different (P=0.21). Serum Malondialdehyde (MDA) in GA and SA
groups did not show a significant difference before surgery (31.14±3.9 mM vs. 29.06±2.49 mM in GA and SA groups,
respectively) (P=0.31), while it was significantly different after surgery (23.14±2.6 mM and 19.24±2.7 mM in GA and SA
groups, respectively) (P=0.03).
Conclusion: lower limb amputation can help to control oxidative stress in diabetic patients; and considering serum
MDA as a marker of oxidative stress, SA seems to be more effective to control this problem.- انتشار مقاله: 07-10-1395
- نویسندگان: Arash Peivandi Yazdi,Alireza Bameshki,Maryam Salehi,Gholamhosein Kazemzadeh,Majid Sharifian Razavi,Shaghayegh Rahmani,Seyed Isaac Hashemy
- مشاهده
- جایگاه : پژوهشی
- مجله: Archives of Bone and Joint Surgery
- نوع مقاله: Journal Article
- کلمات کلیدی: reliability,Persian,validity,Psychometric,Short from McGill pain questionnaire
- چکیده:
- چکیده انگلیسی:
Background: We aimed to develop and validate the Persian version of Short Form McGill Pain Questionnaire-2 (SF-MPQ-2) in patients with knee osteoarthritis.
Methods: Translation and back translation was performed using Beaton’s guideline. After a consensus has achieved on the Persian version of SF-MPQ-2, it was administered to 30 patients with knee osteoarthritis in a pilot study. Then, we enrolled 100 patients with knee osteoarthritis to fill the final SF-MPQ-2 as well as SF-36 and WOMAC questionnaires. Forty-three patients returned 3 days after the initial visit to fill the Persian SF-MPQ-2 for the second time. Construct validity was tested by Pearson’s correlation coefficient between subscales of SF-MPQ-2 and subscales of SF-36 and WOMAC. Internal consistency for total and subscales was calculated by Cronbach’s alpha and reliability between test retest was performed using Intraclass correlation coefficient (ICC).
Results: ICC for subscales of SF-MPQ-2 ranged from 0.73 to 0.90. The ICC for total SF-MPQ-2 was 0.90. Cronbach’s alpha for subscales was 0.65-0.74 at the first visit and 0.58-0.81 at the second visit. Cronbach’s alpha for the total questionnaire was 0.88 and 0.91 at the first and second visit, respectively. Pearson’s correlation coefficient was highly significant when comparing subscales specifically with WOMAC (r=-0.47 to -0.61; P<0.001). Interscale correlation between subscales of SF-MPQ-2 was significant as well (r: 0.43-0.88, P<0.001).
Conclusions: Persian SF-MPQ-2 showed excellent reliability and good to excellent internal consistency throughout the questionnaire. It is a valid and reliable instrument for measuring the pain intensity and applicable in osteoarthritic pain assessment.- انتشار مقاله: 14-12-1392
- نویسندگان: Amir Reza Kachooei,Mohammad H. Ebrahimzadeh,Reza Erfani-Sayar,Maryam Salehi,Ehsan Salimi,Shiva Razi
- مشاهده
- جایگاه : پژوهشی
- مجله: Archives of Bone and Joint Surgery
- نوع مقاله: Journal Article
- کلمات کلیدی: Epidemiology,Childhood,Hand injury
- چکیده:
- چکیده انگلیسی: Background:
Hand injuries are among the most common childhood injuries. No study has been performed regarding the epidemiology of hand injuries in the pediatric population of Iran. This study aimed to examine the epidemiology of hand injuries among children in southeast of Iran.
Methods:
This cross-sectional study was performed via census sampling on patients, aged 16 years or less, with a final diagnosis of hand injury. Patients presenting to the orthopedic department of Khatam-al-Anbia General Hospitalof Zahedan, Iran, were selected from March 2012 to December 2013. Data were analyzed trospectively, using a chart review.
Results:
Two-hundred patients (136 males and 64 females with the mean age of 13±2.8 years) with 205 hand injuries were included in this study. As the results indicated, door-related injuries were the most common type (25%), accounting for 24% and 28% of injuries in male and female patients, respectively (P=0.016). Most injuries occurred at home (64%) and the lowest number was reported at school(22%) (P=0.012). Compared to boys, girls were more likely to be injured at home (78% vs. 57%) (P=0.13). In addition, the dominant hand was mostly injured by doors (28%). The most common type of injury was laceration(81%) and the least common type was finger amputation (7%); also, children with finger amputation were significantly younger than those with other types of hand injuries (P<0.001).Thumb alone (20%) and index and middle fingers together with anequal percentage (3.5%) were the most commonly injured digits. Also, the mean hospitalization cost was 297± 38 dollars.
Conclusions:
Most hand injuries occurred at home and were door-related; they were also more frequentamong younger children. Prospective studies in order to identify specific protective door devices could potentially decrease the frequency of these injures.- انتشار مقاله: 11-05-1393
- نویسندگان: Maryam Mirzaie,Ali Parsa,Maryam Salehi,Mohammad Hallaj Moghadam,Mostafa Dahmardehei,Neda Mirzaie
- مشاهده
- جایگاه : پژوهشی
- مجله: Archives of Bone and Joint Surgery
- نوع مقاله: Journal Article
- کلمات کلیدی: Postoperative pain,Dexmedetomidine,Knee Surgery,Intra-articular
- چکیده:
- چکیده انگلیسی: knee surgery. The purpose of this study was to assess the analgesic effects of intra-articular injection of a dexmedetomidine
following knee arthroscopy.
Methods:
Forty six patients schadualed for arthroscopic knee surgery under general anaesthesia, were randomly
devided into two groups. Intervention group received 1μg/kg dexmedetomidine (D) and isotonic saline. Control group
received 25ml isotonic saline (P). Analgesic effects were evaluated by measuring pain intensity (VAS scores) and
duration of analgesia.
Results:
There was no significant difference between the two groups in terms of age, sex and weight. The mean of
post-operation pain severity in 1, 3, 6,12, and 24 h was significantly lower in the intervention group (D) in comparison
with the control group (P). the mean of the total dose of tramadol consumption was significantly lower in the interven
tion
group in comparison with the control group (
P<0.001).
Conclusions:
Intra-articular injection of dexmedetomidine at the end of arthroscopic knee surgery, alleviates the
patients’ pain; reducing the postoperative need for narcotics as analgesics, and increase the first analgesic request
after operation.- انتشار مقاله: 19-10-1392
- نویسندگان: Mohammad Alipour,Masoomeh Tabari,Reza Farhadifaz,Hadi Makhmalbaf,Maryam Salehi,Seyed Mostafa Moosavitekye
- مشاهده
- جایگاه : پژوهشی
- مجله: Reviews in Clinical Medicine
- نوع مقاله: Journal Article
- کلمات کلیدی: Quality of Life,Questionnaire,reliability,validity,Aberdeen Varicose Vein
- چکیده:
- چکیده انگلیسی: Introduction: Lower-limb varicose is a common disorder, which is caused in some occupations and is exacerbated over time, imposing direct and indirect costs on individuals and the community. The present study aimed to validate the Persian version of Aberdeen varicose vein questionnaire (AVVQ).
Methods: This cross-sectional study was conducted on 75 patients with varicose veins referring to Imam Reza Hospital in Mashhad, Iran in 2014. The subjects were selected via census sampling. The AVVQ was translated into Persian, and its reliability and validity were assessed using face, content, criterion, and construct validity and Cronbach’s alpha coefficient for reliability. To evaluate content validity, the content validity ratio (CVR) was calculated, and the criterion validity was determined based on Pearson’s correlation-coefficient. In addition, the correlation of the obtained score of each questionnaire item with the total score was verified.
Results: The mean age of the patients was 43±16 years. Content validity was assessed based on Lawshe’s method and CVR index of >0.7. The mean score achieved in the AVVQ was 62.3± 8.8, and significant correlations were observed between the total score of AVVQ and physical domain (P<0.001; r=-0.62), mental domain (P<0.001; r=-0.39), and mean total score of SF-36 (P<0.001; r=-0.56). Moreover, the Cronbach’s alpha for the internal consistency of the questionnaire was estimated at 0.71.
Conclusion: According to the results, assessment of the score of quality of life in varicose patients could be an effective approach to the development of proper interventions to improve their quality of life.- انتشار مقاله: 07-12-1397
- نویسندگان: Mahboubeh Neamatshahi,Maryam Salehi,Masoud Pezeshkirad,Maryam Emadzadeh,Sanam Yaghoubi
- مشاهده
- جایگاه : پژوهشی
- مجله: Reviews in Clinical Medicine
- نوع مقاله: Journal Article
- کلمات کلیدی: treatment,lichen planopilaris,Frontal fibrosing alopecia
- چکیده:
- چکیده انگلیسی: Introduction: Lichen planopilaris (LPP) and frontal fibrosing alopecia (FFA) are skin diseases that affect the quality of life. Although a systematic review on LPP and FFA treatment was published in 2013, further updates are needed. The aim of this study is to review systematically the studies published after the last systematic review.
Methods: We searched Scopus, PubMed, Embase, and ISI Web of Science. All the studies published during March 2012-June 2017 were included in this review. Two reviewers separately selected the studies and extracted the data. The results of studies were categorized as unimproved, stabilized, and improved based on the articles reports.
Result: Among the 38 studies, 20, 17, and one studies assessed LPP, FFA, and both treatments, respectively. The papers were case reports, case series, cohorts, and randomized controlled trials. Antimalarial agents and pioglitazone resulted in enhancement in 73 and 71% of the LPP patients, respectively. Improvement and stabilization were observed in almost one third of the topical steroid users and 6/12 of Tacrolimus/Pimecrolimus users in LPP. Improvement and stabilization in FFA was found in 68% of the individuals using antimalarial agents, 83% of intralesional steroid users, all cases of finasteride users, and 95% of the people utilizing dutasteride.
Conclusion: Contrary to the previous systematic review, we found antimalarial agents more effective than steroids in LPP. Finasteride/dutasteride may have favorable impacts on FFA. Intralesional steroids showed to be more effective than antimalarial agents in FFA. Still further studies are needed in order to define a treatment protocol. Low quality and heterogeneity of the articles were among the limitations for making a conclusion.- انتشار مقاله: 16-11-1396
- نویسندگان: Behnoush Bakhshoudeh,Maryam Salehi,Ramin Sadeghi,Alireza Omranzadeh,Toktam Sahranavard,Soheil Arekhi,Ali Jafarzadeh Esfehani,Naghmeh Zabolinejad
- مشاهده
- جایگاه : پژوهشی
- مجله: Reviews in Clinical Medicine
- نوع مقاله: Journal Article
- کلمات کلیدی: Emergency Department,Central venous line,Rapid fluid therapy,Tip misplace
- چکیده:
- چکیده انگلیسی: Central venous line is one of a creative instrument that saves human’s life in critical medical situation. Central venous line access is frequently involved in the disease management. It is used for rapid fluid therapy, transvenous pacemakers, infusion of some medications, hemodialysis or plasmapheresis and etc. Most of the emergency departments have some staffs that are trained for central venous line insertion but related complications occur during central venous line placement.
Central venous line might have some complications and complication follow-up should be considered. Thromboembolism and infection are two important medical complications. Arterial puncture, hematoma, pneumothorax and hemothorax are mechanical Central venous line complications. Chest X-ray and some other techniques should be used for detecting these complications.
Central venous line tip misplace is a considerable problem for emergency department staffs, previously chest X-ray has been used for central venous line misplace detection. In some recent studies, contrast-enhanced ultrasonography and intravascular electrocardiography have been used for central venous line misplace.
- انتشار مقاله: 25-01-1393
- نویسندگان: Ameneh Rezaee Gheshlaghi,Hamid Zamani Moghadam Dolu,Elham Pishbin,Maryam Salehi
- مشاهده
- جایگاه : پژوهشی
- مجله: Reviews in Clinical Medicine
- نوع مقاله: Journal Article
- کلمات کلیدی: children,Epilepsy,Hippocampus
- چکیده:
- چکیده انگلیسی: Many children with hippocampal sclerosis underwent surgery for treatment. Early childhood convulsion occurs in 2 to 4% of population and its prognosis is good in majority of cases. It seems that hippocampal anomalies are common in patients with neocortical epilepsies. The theory of hippocampal sclerosis association with temporal lobe epilepsy has been proposed 100 years ago. Recent studies demonstrated that there was a correlation between memory impairments and prolonged febrile convulsion (PFC), which might be a result of hippocampal injury. Transient hippocampus swelling might happen in complicated early childhood epilepsy or status epilepticus and result in hippocampal sclerosis.
- انتشار مقاله: 29-11-1392
- نویسندگان: Abolfazl Mahmoudzadeh,Yasamin Davoudi,Hossein Haghir,Maryam Salehi,Farah Ashrafzadeh,Behzad Aminzadeh,Sara Mehrnoosh,Mohammadreza Mehrnoosh
- مشاهده
- جایگاه : پژوهشی
- مجله: Reviews in Clinical Medicine
- نوع مقاله: Journal Article
- کلمات کلیدی: Quality of Life,Questionnaire,reliability,validity,Aberdeen Varicose Vein
- چکیده:
- چکیده انگلیسی: Introduction: Lower-limb varicose is a common disorder, which is caused in some occupations and is exacerbated over time, imposing direct and indirect costs on individuals and the community. The present study aimed to validate the Persian version of Aberdeen varicose vein questionnaire (AVVQ).
Methods: This cross-sectional study was conducted on 75 patients with varicose veins referring to Imam Reza Hospital in Mashhad, Iran in 2014. The subjects were selected via census sampling. The AVVQ was translated into Persian, and its reliability and validity were assessed using face, content, criterion, and construct validity and Cronbach’s alpha coefficient for reliability. To evaluate content validity, the content validity ratio (CVR) was calculated, and the criterion validity was determined based on Pearson’s correlation-coefficient. In addition, the correlation of the obtained score of each questionnaire item with the total score was verified.
Results: The mean age of the patients was 43±16 years. Content validity was assessed based on Lawshe’s method and CVR index of >0.7. The mean score achieved in the AVVQ was 62.3± 8.8, and significant correlations were observed between the total score of AVVQ and physical domain (P<0.001; r=-0.62), mental domain (P<0.001; r=-0.39), and mean total score of SF-36 (P<0.001; r=-0.56). Moreover, the Cronbach’s alpha for the internal consistency of the questionnaire was estimated at 0.71.
Conclusion: According to the results, assessment of the score of quality of life in varicose patients could be an effective approach to the development of proper interventions to improve their quality of life.- انتشار مقاله: 07-12-1397
- نویسندگان: Mahboubeh Neamatshahi,Maryam Salehi,Masoud Pezeshkirad,Maryam Emadzadeh,Sanam Yaghoubi
- مشاهده