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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Reviews in Clinical Medicine
- نوع مقاله: Journal Article
- کلمات کلیدی: children,Toxic substances,Suicide Attempt
- چکیده:
- چکیده انگلیسی: Introduction: Poisoning is the most common method of non-fatal suicide. In recent years, poisoning caused by the use of medications and chemicals has increased. The present study aimed to investigate the rate of suicide using toxic compounds in Iranian children.
Methods: This retrospective study was conducted using the data of 83 children aged 5-16 years who attempted suicide using toxic substances and were admitted to the pediatric and toxicology departments of Imam Reza Hospital in Mashhad, Iran.
Results: Among 500 suicide cases, 83 committed suicide using toxic substances, and 8.4% of the suicides were committed by children aged 5-7 years. In addition, 60% of the suicide cases were aged 14-16 years. In total, 45.5% of the children committed suicide with prior planning (statistically significant). The peak time of referral to the emergency department was between 6-12 PM, and more than 90% of the patients were admitted with stable vital signs. The most commonly used toxic substance was organophosphate. During admission, psychiatric counseling was not provided to 36.1% of the patients, and the clinical outcomes also showed the use of non-lethal doses.
Conclusion: According to the results, it is of utmost importance to assess the underlying causes of suicide attempts in early childhood (e.g., prior planning and antisocial behaviors), especially with the increased age of children to 14-16 years in such incidents.- انتشار مقاله: 04-02-1399
- نویسندگان: Farah Ashrafzadeh,Farideh Sahebkar,Anahita Alizadeh,Majid Sezavar,Babak Karimi,Maryam Naseri,Gholamreza Khademi
- مشاهده
- جایگاه : پژوهشی
- مجله: Reviews in Clinical Medicine
- نوع مقاله: Journal Article
- کلمات کلیدی: children,Toxic substances,Suicide Attempt
- چکیده:
- چکیده انگلیسی: Introduction: Poisoning is the most common method of non-fatal suicide. In recent years, poisoning caused by the use of medications and chemicals has increased. The present study aimed to investigate the rate of suicide using toxic compounds in Iranian children.
Methods: This retrospective study was conducted using the data of 83 children aged 5-16 years who attempted suicide using toxic substances and were admitted to the pediatric and toxicology departments of Imam Reza Hospital in Mashhad, Iran.
Results: Among 500 suicide cases, 83 committed suicide using toxic substances, and 8.4% of the suicides were committed by children aged 5-7 years. In addition, 60% of the suicide cases were aged 14-16 years. In total, 45.5% of the children committed suicide with prior planning (statistically significant). The peak time of referral to the emergency department was between 6-12 PM, and more than 90% of the patients were admitted with stable vital signs. The most commonly used toxic substance was organophosphate. During admission, psychiatric counseling was not provided to 36.1% of the patients, and the clinical outcomes also showed the use of non-lethal doses.
Conclusion: According to the results, it is of utmost importance to assess the underlying causes of suicide attempts in early childhood (e.g., prior planning and antisocial behaviors), especially with the increased age of children to 14-16 years in such incidents.- انتشار مقاله: 04-02-1399
- نویسندگان: Farah Ashrafzadeh,Farideh Sahebkar,Anahita Alizadeh,Majid Sezavar,Babak Karimi,Maryam Naseri,Gholamreza Khademi
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Basic Medical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: DPPH,FRAP,Lamiaceae,Isorhoifolin,Jaranol,Mushroom tyrosinase - inhibition assay,Poliumoside,Teucrium polium var.- gnaphalodes
- چکیده:
- چکیده انگلیسی:
Objective(s): In food industry, the inhibition of tyrosinase is very important, because this enzyme catalyzes the oxidation of phenolic compounds found in fruits and vegetables into quinones, which contribute in undesirable color and taste of fruits and vegetables. Teucrium polium L. var. gnaphalodes (Lamiaceae), a wild-growing flowering plant that has many applications in food preparations and traditional medicine. In Persian language, this medicinal herb is called Kalpoureh.
Materials and Methods: 1D- and 2D-NMR experiments were used to determine the chemical structures of the isolated compounds. Antioxidant and tyrosinase inhibitory activities of the isolated compounds were evaluated using DPPH, FRAP and mushroom tyrosinase inhibition assays.
Results: In this research, we isolated two phenylpropanoid glycosides including verbascoside and poliumoside and two flavonoids including jaranol and isorhoifolin using chromatographic techniques. We found promising antioxidant and anti-tyrosinase compounds from Teucrium polium L. var. gnaphalodes.
Conclusion: To date, different compounds have been isolated and characterized from T. polium including terpenoids and flavonoids. But no phytochemical study has been reported from T. polium var. gnaphalodes. Poliumoside and jaranol showed promising antioxidant and tyrosinase inhibitory activities, respectively.- انتشار مقاله: 10-06-1395
- نویسندگان: Zahra Boghrati,Maryam Naseri,Mitra Rezaie,Ngoc Pham,Ronald J Quinn,Zahra Tayarani-Najaran,Mehrdad Iranshahi
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: children,Parents,Internet,Health Information Sources
- چکیده:
- چکیده انگلیسی: Background
For parents with sick children, the health care team is not the only source of receiving information, they try to use different sources. We aimed to evaluate the information seeking behavior of parents regarding health and medical issues.
Materials and Methods: This cross-sectional study was performed on parents of children referred to Dr. Sheikh Hospital and Hazrat Rasoul Center, Mashhad, Iran, from 2016 to 2018. 550 people filled an indigenous reliable questionnaire (a tool to evaluate information seeking behavior of parents of sick children) with Cronbach's alpha coefficient of 0.934. The exclusion criterion was parental dissatisfaction with participating in the study. The questionnaire is organized in 40 questions and 6 sectionsincluding demographic information, needs and motivations about data search, Internet usage, questions about data resources, obstacles to data search, and impact of data.
Results: Parents searched various resources to obtain information about child health especially regarding the diagnosis of the child's disease, diet, and child growth and more than half of parents spent less than 2 hours per week for getting information. 31.8% of parents searched the Internet 2 to 5 times a week for health information. The most important reasons for parents to search the Internet were to get more information than what the doctor tells those (53.08%), and to look for alternative and traditional treatments (36.9%). According to parents, the most important limitation of the information obtained from the Internet can be its unreliability (63.09%).
Conclusion
The results showed that medical staff and the Internet had priority over other sources in obtaining information about the child's illness, however, health care team was trusted more by the respondents.- انتشار مقاله: 16-06-1399
- نویسندگان: Yalda Ravanshad,Anoush Azarfar,Gholamreza Khademi,Atieh Mohammadzadeh,Majid Sezavar,Maryam Naseri
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: Premature Infants,Quran,Physiological response
- چکیده:
- چکیده انگلیسی: Background: One of the most important methods of complementary medicine is music and phonotherapy and one of the most beautiful sounds is the sound from the recitation of the Quran. We aimed to investigate the effect of the sound of the Quran on physiological responses in preterm infants.
Materials and Methods: All clinical trials evaluating the Effect of the Sound of the Holy Quran on the physiological responses in premature infants were searched in the online databases of Scopus, EMBASE, Cochrane, Web of Science and Medline with no language or time restrictions up to the end of Feb. 2019, using the combination related keywords of Mesh. Two reviewers did study selection.
Results: Five studies with a sample size of 360 were included in this review. In the first study, the mean of respiratory and heart rates significantly decreased and oxygen saturation levels increased in the Quran group compared to the control groups. In the second study, there was a significant difference in the oxygen saturation, respiratory rate, and heart rate between the two groups. In the third study, there was a significant difference in arterial blood oxygen levels and heart rates between the groups. In the fourth study, two groups (Quran recitation and control) were surveyed at minute 10 and 20 of intervention, also at minute10 post intervention; there were significant differences in respiratory rates and oxygen saturation levels at the three time points. In the fifth study, results did not indicate any significant differences in the mean of responses in four groups (Quran recitation, lullaby music, silence, and control groups).
Conclusion
Listening to recitation of the Quran can improve physiological parameters (reduced heart and respiratory rates, and increased oxygen saturation level) in preterm infants.- انتشار مقاله: 20-12-1398
- نویسندگان: Leila Kazemian,Maryam Sabaghian,Ayoub Tavakolian,Mohammad Reza Hadipanah,Maryam Naseri,Elaheh Mansori,Omolbanin Heydari,Mahla Salarfard
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: Cerebral palsy,Preterm infant,Intracerebral Hemorrhage
- چکیده:
- چکیده انگلیسی: Background: Intracerebral hemorrhage (ICH) is a type of intracranial bleed that occurs within the brain tissue or ventricles. The present study aimed to review the association between ICH and cerebral palsy (CP) in the preterm infants.
Materials and Methods: In the systematic review, the electronic databases of Medline, Web of Science, Cochrane, EMBASE, and Scopus were systematically searched to find the relevant studies using the main keywords of (Premature OR Preterm OR Premature Infant OR Premature Birth) AND (Cerebral Palsy) AND (Brain Hemorrhage OR Intracranial Hemorrhages OR Cerebral Hemorrhage OR Putaminal Hemorrhage) up to October 26, 2019.
Results: Finally, three studies with 1,730 participants were enrolled in this study. In the first study, results showed no strong association between early brain lesions with subsequent neurological consequences; in addition, the association between chorioamnionitis in intrauterine life was not substantiated with the incidence of brain lesions. In the second study, results showed progression of brain lesions and neurodevelopmental disorders like other previous studies in the follow-up of very preterm (VPT) infants up to the age of two; overall, the preterm infants are at greater risk of brain damage and neurodevelopmental disorders than term infants, independent of risk factors. In the third study, a neurological assessment was performed in the fourth, 8th, 12th, and 18th months to detect the function of the neuromotor system and CP, with higher degrees of cerebral hemorrhage associated with a higher prevalence of neurodevelopmental defects.
Conclusion: Cerebral hemorrhage is considered a very important pathologic factor in preterm and low birth weight infants, which is associated with irreversible consequences of neurocognitive development.- انتشار مقاله: 16-10-1398
- نویسندگان: Sara Rahafard,Reza Ahmadi,Ayoub Tavakolian,Omolbanin Heydari,Hamed Jafarpour,Morteza Behnamfar,Roozbeh Nasibeh,Farzane Ashrafinia,Maryam Naseri
- مشاهده
- جایگاه : پژوهشی
- مجله: Asia Oceania Journal of Nuclear Medicine and Biology
- نوع مقاله: Journal Article
- کلمات کلیدی: Sentinel Lymph Node Biopsy,Thyroidectomy,Papillary thyroid cancer
- چکیده:
- چکیده انگلیسی: Objective(s): In patients with papillary thyroid cancer (PTC), sentinel lymph node (SLN) radio-guided biopsy is not routinely used for detection of involved neck lymph nodes (NLN); 99mTc- antimony sulfide colloid (99mTc- ASC) has been used for this purpose. In this study, besides 99mTc-ASC another radiotracer, 99mTc-phytate (99mTc-P) with different doses and injection methods were evaluated.
Methods: Twenty-two patients, scheduled to undergo thyroidectomy for PTC, were injected for radio-guided SLN biopsy in the morning of operation in 3 groups: intra tumoral injection of about 1 mCi 99mTc-P (group A; n=5); peritumoral injection of less than 3 mCi 99mTc-ASC (group B; n=6); and peritumoral injection of 3 to 5 mCi 99mTc-ASC with application of massage (group C; n=9). A patient refused to complete the study. A patient with follicular thyroid cancer was also excluded. No NLN was detected in the pre-operative ultra-sonographic examinations of all patients. Central neck dissection was done for all the participants. The presence of radio guided detected NLN and results of pathology were assessed.
Results: In group A and B, no SLN was detected. NLNs were resected in 4 patients in group A and B; 2 of them involved by the tumor. In group C, 6 out of 9 patients (66.7%) had between 1 to 6 SLNs; the procedure failed to detect NLN in a patient in group C with surgically resected reactive NLN (failure rate 1 out of 7). Conclusion: The results underscored the significance of SLN radio guided biopsy in patients with PTC; the radiotracer, dose and method of injection may affect the detection rate.- انتشار مقاله: 04-05-1399
- نویسندگان: Abbas Alibakhshi,Saeed Farzanehfar,Mahya Zarei,Mohammad Eftekhari,Maziar Motiee,Maryam Naseri,Mehrshad Abbasi
- مشاهده