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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: breast reconstruction pain,analgesia,muscle relaxants,spasmolytic,thiocochlicoside
- چکیده:
- چکیده انگلیسی: Purpose: Post-operative pain after breast cancer surgery is a major problem and women undergoing mastectomy
and breast reconstruction experience post-operative pain syndromes in approximately one-half of all cases. Patients
who have undergone breast reconstruction after mastectomy can suffer from acute postoperative pain with moderate
or strong tension. In some cases, chronic neuropathic pain syndromes may occur after surgery. Opioids are used to
treat pain, with serious side effects. The systemic postoperative analgesic regimen as thiocochlicoside P.O. along
with paracetamol and NSAIDs I.V., which may limit the administration of opioids without reducing pain relief,
seems to be necessary. Materials and Methods: This study was a clinical trial randomizing 70 patients undergoing
breast reconstruction. Two main protocols of systematic post-operative analgesia, one using thiocochlicoside (group
A) and the other without them (group B), were used. Both groups received paracetamol X3 and lornoxicam X2 I.V.
systematically. The pain measurement scale (NPS) used to measure post-operative pain. Likert scales were used to
evaluate patient’s satisfaction and the difficulty from the side effects . An anonymous questionnaire was used for the
data collection. Results: Statistically significant difference was found between pain on the day of surgery (p = 0.017)
as well as the three subsequent days (p = 0.000). In group A , pain was reduced directly to half (Χ2 surgery pain =
93.888, p = 0.000) especially on the first post-operative day. In group A the satisfaction with analgesic treatment was
higher than in group B (p = 0.002). Conclusion: The use of thiocochlicoside in post-operative analgesia in breast
reconstruction after mastectomy contributes to reduce the pain intensity experienced by patients and to reduce the side
effects of opioid analgesics as a result of reduced demand for opioid analgesics. Patients who received the analgesia
using muscle relaxants-spasmolytic reported greater satisfaction.- انتشار مقاله: 01-03-1397
- نویسندگان: Maria Bourazani,Effie Papageorgiou,Georgios Zarkadas,Theodora Petrakopoulou,Evridiki Kaba,Georgia Fasoi,Martha Kelesi
- مشاهده
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: anxiety,depression,Breast cancer,Psychological distress,Predictors
- چکیده:
- چکیده انگلیسی: Introduction: Having breast cancer or receiving treatment has been seen as a traumatic experience for women due
to its impacts on their self-image and sexual relationship, and may lead to an psychological reactions such as denial,
anger, or intense fear toward their disease and treatment process. Also many of breast cancer patients have psychiatric
morbidities such as depression and anxiety. Purpose: The purpose of this study was to assess the prevalence and
associated factors of depression and anxiety in breast cancer patients, in order to identify independent predictors of mental
health disorders risk. Material and Methods: A cohort of 152 breast cancer patients who were attending an outpatient
oncology department was recruited. Data were collected with a structured questionnaire consisted by social, clinical
and demographic information and PHQ-2 and GAD-2 scales. Results: The mean age of the patients was 53.25 years
(SD=12.10), 69.7% of the patients underwent mastectomy and 30.3% ongectomy. Chemotherapy received 46.1% of
patients as adjuvant therapy, 15.8% radiotherapy and 38.2% received both chemotherapy and radiotherapy. A large
percentage found to be classified as depressed (38.2%) and anxious (32.2%) and factors that found to be associated
were age, marital status, educational level, stage of cancer from univariate analyses and place of residence, religion,
symptoms burden from multivariate analysis (for depression and anxiety). Conclusions: Breast cancer patients are
in high risk for developing psychiatric disorders such as depression and anxiety. Being rural resident, non-Orthodox
Christian and experiencing extend symptom burden can be predicting factors associated with depression and anxiety
in breast cancer patients.- انتشار مقاله: 16-10-1396
- نویسندگان: Konstantinos Tsaras,Ioanna V Papathanasiou,Dimitroula Mitsi,Aikaterini Veneti,Martha Kelesi,Sofia Zyga,Evangelos C Fradelos
- مشاهده