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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: International Journal of Horticultural Science and Technology
- نوع مقاله: Journal Article
- کلمات کلیدی: Free radicals,Asteraceae,Alpine area,endemic species,Officinal plants,terpenes,Yarrow
- چکیده:
- چکیده انگلیسی: Achillea moschata Wulfen (Asteraceae) is an endemic species growing on the Alps and traditionally used in several medicinal remedies. For its aromatic properties, it is also collected for food purposes. Chemical content and biological activity of A. moschata oil are not extensively studied. We investigated whether the different lithological and geomorphological features of two alpine areas including Vallone dello Scerscen and Valle dei Ratti, located in the Sondrio Province (Northern Italy), can influence the essential oil (EO) composition and the related antioxidant activity of the respective A. moschata populations. The essential oils obtained by steam distillation from the dried aerial parts were investigated by GC/FID and GC/MS. Several compounds were identified belonging to different chemical classes, including monoterpenes and sesquiterpenes as the most abundant constituents, together with ketones, alcohols, phenols, acids and esters. A variation in the quantitative composition of several constituents was recorded in the two oils. The main constituents were camphor (23.4-34.2%), 1,8-cineole (9.8-16.4%), trans-tujone (3.6-13.4%), sesquicineole (3.5-5.8%), borneol (1.1-4.8%), -caryophyllene (2.7-4.4%) and myrcene (1.3-4.2%). Their antioxidant activity was measured in vitro by the 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS⋅+) and 2,2-diphenyl-picryl hydrazyl (DPPH⋅) stable radical assays. The essential oils showed similar and significant scavenger effects, possibly due to the synergistic action of all components including compounds present in small quantities.
- انتشار مقاله: 19-01-1399
- نویسندگان: Aldo Tava,Marcello Iriti,Sara Vitalini
- مشاهده
- جایگاه : پژوهشی
- مجله: Asian Pacific Journal of Cancer Prevention
- نوع مقاله: Journal Article
- کلمات کلیدی: Diagnosis,treatment,Thyroid cancer,lncRNA,genetic alterations
- چکیده:
- چکیده انگلیسی: Thyroid cancer (TC) is the most common cancer of endocrine system. TC can be subdivided into 4 different entities, papillary, follicular, medullary and anaplastic thyroid cancer. Among them, anaplastic thyroid cancer has the poorest prognosis. Exploring new therapeutic approach may entail favorable prediction as well as increasing overall survival rate of patients. Long non-coding RNAs (lncRNAs), have vast implications in different cancer types. Although they are not transcribed into proteins, they can act as a harness in regulating a plethora of biological functions. They have been implicated in a decisive role in gene expression via modulation of both coding and non-coding RNAs. This article discuss the multi-facet role of lncRNA in thyroid cancer biology.
- انتشار مقاله: 28-10-1397
- نویسندگان: Zeeshan Javed,Faiez Ahmed Shah,Sadegh Rajabi,Qamar Raza,Zaheer Iqbal,Mukhtar Ullah,Touqeer Ahmad,Bahare Salehi,Mehdi Sharifi-Rad,Raffaele Pezzani,Farooq Yaqoob,Haleema Sadia,Marcello Iriti,Javad Sharifi-Rad,William C Cho
- مشاهده