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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Journal of Medicinal and Chemical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: Kinetics,Ultrasound,indole,Benzyl chloride,Interfacial reactions
- چکیده:
- چکیده انگلیسی: The ultrasound assisted preparation of 1-benzyl-1-indole (arylation) from the reaction of benzyl chloride (BC) and indole was carried out successfully using solid sodium hydroxide and catalyzed by multi-site phase-transfer catalyst (MPTC) viz., 1,4-benzyl-1,4-diazoniab-icyclo[2.2.2]octanium dichloride in a solid–liquid reaction condition (SL-PTC). Water was introduced in a trace quantity to the reaction system to avoid a serious hydration of active intermediate. The potentiality of the multi–site phase-transfer catalyst was demonstrated by following the kinetics arylation of indole under pseudo–first order conditions by employing aqueous sodium hydroxide and indole in excess. The reaction was monitored by gas Chromatography. The synthesized MPTC and 1-benzyl-1-indole were characterized by 1H NMR and 13C NMR. The reaction is greatly enhanced in the solid–liquid system, catalyzed by multi-site quaternary ammonium salt (MPTC) and ultrasound irradiation (28 kHz, 300W) in a batch reactor.
- انتشار مقاله: 11-03-1397
- نویسندگان: Manickam Sathiyaraj,PERUMAL VENKATESH
- مشاهده
- جایگاه : پژوهشی
- مجله: Asian Journal of Green Chemistry
- نوع مقاله: Journal Article
- کلمات کلیدی: Sonocatalysis Interfacial Reaction Kinetics MPTC 1,3-dibromo propane
- چکیده:
- چکیده انگلیسی: In the present study, kinetics of synthesis of spiro[cyclobutane-1,2’-indene]-1’,3’-dione was successfully carried out by spirolation of indene-1,3-dione with 1,3-dibromo propane using aqueous potassium hydroxide and catalyzed by a newly synthesized multi-site phase-transfer catalyst viz., 1,3,5-tribenzyl-1,3,5-triethyl-1,3,5-triazinane-1,3,5-triiu tribromide (MPTC), under ultrasonic (40 kHZ, 300 W) assisted organic solvent condition. The pseudo first-order under the ultrasound irradiation (40 kHz, 300 W) in a batch reactor, the overall reaction was greater than that of without ultrasound.
- انتشار مقاله: 24-02-1397
- نویسندگان: Manickam Sathiyaraj,Perumal Venkatesh
- مشاهده
- جایگاه : پژوهشی
- مجله: Asian Journal of Green Chemistry
- نوع مقاله: Journal Article
- کلمات کلیدی: Antimicrobial activity,Antioxidant,Ocimum basilicum,Ag-NPs
- چکیده:
- چکیده انگلیسی: To resolve the efficacies of antibacterial, antifungal, and antioxidant activities of aqueous leaf extract of Ocimum basilicum mediated biosynthesis of silver nanoparticles (Ag-NPs). Aqueous and synthesized Ag-NPs were tested by disc diffusion method against the bacterial and fungal pathogens. Antioxidant activity of synthesized Ag-NPs and aqueous plant extract were determined. The scavenging radicals were estimated by DPPH method. The synthesized Ag-NPs were characterized by XRD, FT-IR, FESEM and EDX. XRD peaks at 2θ values of 27.6°, 32.2°, 38.16°, and 46.04° representing the (110), (111), (121), and (200). FT-IR absorption peak located at 2910 cm-1 are due to C–H stretch of alkenes and a peak at 1669 cm-1 due to -C=C- band of alkenes and a peak at 1614 cm-1 is assigned to N-H bend of 1° amines and a peak at 1092 cm-1 due to C–N stretch of aliphatic amines and a peak at 875 cm-1 are due to C–H stretch of aromatics. TEM study reveals that most of the nanocrystals formed were spherical and polyphedral in shape antibiotics inhibition zones against the bacteria Staphylococcus aureus, Escherichia coli, Klebselia pneumonia, Proteus mirabilis, Proteus valgar is using the nanoparticles 8.9, 9.2, 7.8, 8.1, and 7.4 mm. Ag-NPs exhibited strong antibacterial activity antifungal activity versus Asfergillus flavus, Asfergillus terreus, Asfergillus niger, Asfergillus fumigates exhibited a 7.8, 7.5, 6.9, and 7.1 mm inhibition zone using the Ag-NPs. Green synthesized Ag-NPs provides a promising approach can satisfy the requirement of large-scale industrial production bearing the advantage of low-cost, eco-friendly and reproducible.
- انتشار مقاله: 14-03-1397
- نویسندگان: Devan Elumalai,Manickam Sathiyaraj,Elangovan Vimalkumar,Patheri Kunyl Kaleena,Maduraiveeran Hemavathi,Perumal Venkatesh
- مشاهده