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کاربرد نوع شرط:
- جایگاه : پژوهشی
- مجله: Reviews in Clinical Medicine
- نوع مقاله: Journal Article
- کلمات کلیدی: Ultrasonography,Infant,Newborn
- چکیده:
- چکیده انگلیسی: Introduction: Ultrasonographic assessment of the kidney size in newborns is essential to the diagnosis of renal diseases during the neonatal period. According to the literature, altered renal dimensions may lead to changes in the kidney echotexture in certain renal pathologies. This systematic review aimed to evaluate the renal dimensions in premature and term neonates.
Methods: This systematic review was conducted to identify the English articles on the renal dimensions of children and premature/term neonates via searching in databases such as PubMed, Google Scholar, and Scopus. In total, 74 studies were retrieved from the electronic databases. After reviewing the titles and abstracts, 10 articles that were in line with the study objectives were selected in full text and evaluated.
Result: The studies on the renal dimensions of newborns had been performed on various populations. Some studies had compared kidney diameters with the body weight and length of the neonates within the first days of birth, while some others had compared the gestational age of neonates with their kidney size. However, no conclusive results were proposed. In addition, several studies were found on kidney size during the fetal period and childhood, while limited investigation was available regarding the neonatal period. In the present study, we analyzed the correlations between the renal dimensions of neonates and their gestational age, length, weight, and body surface area by reviewing the current literature.
Conclusion: Although renal volume is considered to be the most precise index of the kidney size, renal length is evidently the most practical indicator of renal dimensions, which is correlated with the anthropometric indices and gestational age of neonates.- انتشار مقاله: 24-08-1394
- نویسندگان: Mandana Kashaki,Ladan Younesi,Marjan Esmaeili,Hasan Otoukesh,Mohammad Esmaeili
- مشاهده
- جایگاه : پژوهشی
- مجله: Reviews in Clinical Medicine
- نوع مقاله: Journal Article
- کلمات کلیدی: Ultrasonography,Infant,Newborn
- چکیده:
- چکیده انگلیسی: Introduction: Ultrasonographic assessment of the kidney size in newborns is essential to the diagnosis of renal diseases during the neonatal period. According to the literature, altered renal dimensions may lead to changes in the kidney echotexture in certain renal pathologies. This systematic review aimed to evaluate the renal dimensions in premature and term neonates.
Methods: This systematic review was conducted to identify the English articles on the renal dimensions of children and premature/term neonates via searching in databases such as PubMed, Google Scholar, and Scopus. In total, 74 studies were retrieved from the electronic databases. After reviewing the titles and abstracts, 10 articles that were in line with the study objectives were selected in full text and evaluated.
Result: The studies on the renal dimensions of newborns had been performed on various populations. Some studies had compared kidney diameters with the body weight and length of the neonates within the first days of birth, while some others had compared the gestational age of neonates with their kidney size. However, no conclusive results were proposed. In addition, several studies were found on kidney size during the fetal period and childhood, while limited investigation was available regarding the neonatal period. In the present study, we analyzed the correlations between the renal dimensions of neonates and their gestational age, length, weight, and body surface area by reviewing the current literature.
Conclusion: Although renal volume is considered to be the most precise index of the kidney size, renal length is evidently the most practical indicator of renal dimensions, which is correlated with the anthropometric indices and gestational age of neonates.- انتشار مقاله: 24-08-1394
- نویسندگان: Mandana Kashaki,Ladan Younesi,Marjan Esmaeili,Hasan Otoukesh,Mohammad Esmaeili
- مشاهده
- جایگاه : پژوهشی
- مجله: Journal of Kerman University of Medical Sciences
- نوع مقاله: Journal Article
- کلمات کلیدی: Newborn Meningitis Cerebrospinal fluid C,reactive protein Sepsis
- چکیده:
- چکیده انگلیسی: Background: Meningitis is a common life threatening infection in neonatal period. Diagnostic value of CSF-CRP level in bacterial meningitis in children and adults has been studied worldwide, but there are limited studies on CSF-CRP in neonatal meningitis. This study conducted to assess any relation between CSF-CRP and plasma CRP levels and abnormal CSF findings in neonates suspected to meningitis. Methods: Seventy five hospitalized neonates suspected to meningitis were enrolled in this cross sectional study. All infants were gone through a complete sepsis workup including blood and CSF CRP. Results: CSF-CRP level had statistically significant correlation with serum WBC (p= 0.048) and also poor correlation with CSF protein level (p= 0.054). Serum CRP level had statistically significant correlation with CSF WBC (p= 0.008). Conclusion: No correlation found between CSF and serum CRP levels of patients in this study. Although, CSF-CRP is a rapid and easy to interpret test, it can be performed alongside CSF cytology and biochemical analysis, smear and culture as a confirmatory test for definite diagnosis of neonatal meningitis.
- انتشار مقاله: 23-02-1399
- نویسندگان: Mandana Kashaki,Elahe Norouzi,Saeideh Heidarali,Parisa Mohagheghi,Mahmoud Soltani,Hamid Karbalaei Hasani Karbalaei Hasani
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Neonatology
- نوع مقاله: Journal Article
- کلمات کلیدی: Infant,blood pressure,Newborn,Nomograms,Gestational Age
- چکیده:
- چکیده انگلیسی: Background: Blood pressure (BP) is an important vital sign and indicator of clinical stability. Therefore, the accurate measurement and interpretation of this physiological signal is essential for the optimal management of ill newborns. In this regard, the present study aimed to determine BP values and percentiles in stable newborns in the first weeks of life and evaluate the relevant factors.
Methods: This prospective observational study was conducted on 320 term and preterm newborns between 26 and 42 weeks gestational age (GA) within 2015-2017. The exclusion criteria entailed: 1) birth asphyxia,2) preeclampsia, 3) gestational diabetes mellitus (GDM) type I, 4) illicit substance use, and 5) major congenital anomaly. The oscillometric technique was used for BP measurement and systolic and diastolic BPs were analyzed by regression analysis for various percentiles (5th to 95th).
Results: The neonates in the current study consisted of 185 (57.8%) males and 135 (42.2%) females with mean (SD) birth weight of 2058.3±582.5grams. Mean (SD) gestational age was reported as 32.95(3.97) weeks. 69.1 % of neonates were delivered via cesarean section. Percentile charts (5th- 95th values) which were developed for systolic (SBP) and diastolic (DBP) demonstrated a steady rise on the respective days that were comparable between different groups. Term neonates were found to have higher BPs, compared to their preterm counterparts on the respective days. Moreover, the neonates who were delivered vaginally had higher mean BP values than neonates delivered via cesarean section.
Conclusion: The current study provided normative BP values among neonates, especially in the first two weeks of life. Data presented in this study which include delivery-mode-specific BP percentile curves using an oscillometric method serve as a valuable reference for physicians in the management of newborns in the neonatal unit.- انتشار مقاله: 26-05-1398
- نویسندگان: Nasrin Khalesi,Nakysa Hooman,Mandana Kashaki,Reyhane Bayat,Asma Javid,Soraya Shojaee,Afshin Safaeiasl,Soheila Mahdavynia
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Neonatology
- نوع مقاله: Journal Article
- کلمات کلیدی: urinary tract infection,neonates,Meningitis
- چکیده:
- چکیده انگلیسی: Background: Bacteremia is relatively common in children with urinary tract infection (UTI). The aim of the present study was to determine the frequency of bacterial meningitis among neonates with laboratory-confirmed UTI.
Methods: This retrospective cross-sectional study was performed on 163 hospitalized neonates in Ali Asghar and Shahid Akbarabadi hospitals affiliated to Iran University of Medical Sciences in Tehran, Iran. The demographic and clinical data of hospitalized neonates due to UTI during the recent 6 years (2010-2016) who were aged < 28 days and had cerebrospinal fluid (CSF) culture via lumbar puncture were extracted from medical records and recorded in some checklists.
Results: A total of 163 neonates with laboratory-confirmed UTI with the mean age of 18.25±5.41 days were included. In this study, 54% of the neonates were male. Out of all neonates, 23 (14.1%) cases had positive blood culture. The positive CSF culture was observed in only two (1.2%) neonates. Positive voiding cystourethrogram (VCUG) test was reported in 50% of the neonates with positive CSF culture (P=0.047). Although abnormal ultrasound findings related to the urinary tract in positive CSF neonates were higher by approximately twofold, compared to those reported for negative CSF neonates, this difference was not statistically significant (50% and 24.2%, respectively; P=0.432).
Conclusion: The frequency of the concurrent occurrence of UTI and meningitis in our neonates was 1.2%. Out of all indicators associated with meningitis occurrence, positive VCUG may be a risk factor. Further prospective studies are needed to approve these results.- انتشار مقاله: 29-03-1398
- نویسندگان: Maryam Saboute,Mandana Kashaki,Rahman Yavar,Arash Bodbar,Nasrin Khalessi,Leila Allahqoli
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Neonatology
- نوع مقاله: Journal Article
- کلمات کلیدی: Growth,Protein,ELBW infants
- چکیده:
- چکیده انگلیسی: Background: Breast milk provides adequate protein to facilitate growth for term infants. Appropriate nutrition is necessary for the growth of preterm infants. Extremely-low-birth-weight (ELBW) infants require higher protein intakes to achieve adequate growth.
The present study aimed to evaluate the effect of protein supplements on the physical growth of infants weighing less than 1,000 grams through the serial measurement of their anthropometric indices (weight, height, and head circumference) during admission at the neonatal intensive care unit (NICU).
Methods: This triple-blind, randomized clinical trial was conducted on 64 infants weighing less than 1,000 grams, who were admitted to the NICU of Akbar Abadi Hospital in Tehran, Iran during 2015-2016. Data on the daily nutritional intake of the subjects were recorded until discharge from the hospital. Data analysis was performed in SPSS version 24.
Results: In total, 63 infants were enrolled in the study. Mean daily weight gain of the infants was 55.92±36.90 and 30.80±13.91 grams in the case and control groups, respectively (P=0.001). Mean weekly linear growth in the case and control groups was 0.77±0.67 and 0.76±0.29 centimeter, respectively (P=0.939). Mean weekly head circumference growth in the case and control groups was 0.51±0.10 and 0.34±0.16 centimeter, respectively (P<0.001).
Conclusion: According to the results, protein therapy in the premature, extremely-low-birth-weight (ELBW) infants could improve the rate of weight gain and head circumference growth. Given the importance of weight gain in premature ELBW infants, it is recommended that protein therapy be employed in these newborns. Various studies have denoted the few side-effects of protein therapy, which indicates the safety of this method to resolve the lack of weight gain in these infants.- انتشار مقاله: 22-06-1397
- نویسندگان: Mandana Kashaki,Ali Mazouri,Arash Bordbar,Maryam Saboute,Zahra Behnamfar,Atefeh Talebi
- مشاهده
- جایگاه : پژوهشی
- مجله: Iranian Journal of Neonatology
- نوع مقاله: Journal Article
- کلمات کلیدی: Nephrotoxicity,Prematurity,Sepsis,Amikacin,Drug regimen
- چکیده:
- چکیده انگلیسی: Background: Bacterial sepsis is highly prevalent among premature infants. Amikacin is an antibiotic widely recommended for the treatment of neonatal sepsis, one of the consequences of which might be nephrotoxicity. The present study aimed to compare the efficacy and nephrotoxicity of multiple daily dosing (MDD) and once-daily dosing (ODD) of amikacin in preterm infants suspected of sepsis.
Methods: This triple-blind, randomized, controlled clinical trial was conducted on 40 premature infants suspected of sepsis, who were randomly divided into two groups. In addition to ampicillin, one group was administered with the standard daily dose, and the other group received an ODD of intravenous amikacin. Maximum and minimum serum levels of amikacin and urine neutrophil gelatinase-associated lipocalin (NGAL) were measured in both groups. Data were extracted and analyzed based on the research hypothesis and literature review.
Results: No significant differences were observed between the study groups in terms of gender, gestational age, mode of delivery, birth weight, and Apgar score. After the intervention, mean plasma creatinine reduced in both groups, while the mean reduction was significantly higher in the group administered with the ODD of amikacin (P=0.0001). However, mean changes in the urine NGAL had no significant difference between the groups (P=0.635). Minimum and maximum serum levels of amikacin in the study groups indicated a more significant reduction in mean level of the infants administered with the ODD of amikacin compared to the MDD group (P=0.0001).
Conclusion: Considering the higher maximum and lower minimum levels of amikacin in the neonates receiving the daily dosage regimen, it seems that this regimen is more effective in the treatment of sepsis in preterm infants. Moreover, no significant difference was observed in the efficacy and nephrotoxicity of the daily amikacin dosing in the premature infants suspected of sepsis compared to those treated by multiple doses of amikacin.- انتشار مقاله: 29-09-1396
- نویسندگان: Arash Bordbar,Ali Mazouri,Mandana Kashaki,Majid Kalani,Maryam Saboute,Rozita Hosseini,Somayeh Farhadi,Ali Ghassemian
- مشاهده
- جایگاه : پژوهشی
- مجله: International Journal of Pediatrics
- نوع مقاله: Journal Article
- کلمات کلیدی: Knowledge,Practice,Educational intervention,Neonatal Jaundice
- چکیده:
- چکیده انگلیسی: Background: Raising awareness of mothers has an important role to preventing neonatal severe hyperbilirubinemia. We aimed to investigate the role of educational intervention on the knowledge and practice of the mothers with icteric newborns. Materials and Methods: This study was interventional study with interventional and control group. Study population consisted of 384 consecutive parents of newborns with jaundice, who were admitted to Mahdieh and Mofid hospitals in Tehran- Iran, during 2013 to 2014. The participants were randomly assigned to the trained group (n = 192), who receiving educational programs in three sessions that each sessions was about 45 minutes and the control group (n = 192), without any educational intervention Two months after completing the educational program, the level of knowledge and practice of women in both groups was assessed by using the same questionnaire. The data were analyzed by using SPSS software. Results: The mean score for the level of knowledge toward neonatal jaundice was higher in educational group compared to the control group (7.5 ± 2.5, ranged 2 to 15 versus 4.7 ± 1.3 ranged 1 to 7, P < 0.001). The level of knowledge toward neonatal jaundice reached 72% in educational group that remained 39% in control mothers. The mean score for practice of mothers to neonatal jaundice was significantly higher in trained mothers than in untrained ones (13.7 ± 3.8 ranged 7 to 19 versus 5.9 ± 2.1 ranged 3 to 7, P < 0.001). Also, high score for practice in trained and untrained women was 84% and 67%, respectively that was significantly higher in former group (P<0.05).
Conclusion: Despite low level of knowledge and practice of mothers with jaundiced neonates, training programs in our experience led to significantly improving the level of knowledge and practice in this population.- انتشار مقاله: 04-05-1395
- نویسندگان: Mandana Kashaki,Mohammad Kazemian,Abolfazl Afjeh,Mostafa Qorbani,Omid Safari,Babak Rastegari Mehr,Tahereh Pashaei,Hossein Ansari,Hamid Asayesh,Zahra Shafieyan,Morteza Mansourian
- مشاهده